MRP8, ATP-binding cassette C11 (ABCC11), is a cyclic nucleotide efflux pump and a resistance factor for fluoropyrimidines 2′,3′-dideoxycytidine and 9′-(2′-phosphonylmethoxyethyl)adenine

Journal of Biological Chemistry

Volumn 278, Issue 32, 2003, Pages 29509-29514

  Guo, Yanping ^a   Kotova, Elena ^a   Chen, Zhe Sheng ^a   Lee, Kun ^a   Hopper Borge, Elizabeth ^a   Belinsky, Martin G ^a   Kruh, Gary D ^a  

^a FOX CHASE CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINETRIPHOSPHATE; CELLS; DNA; DRUG PRODUCTS;

FUNCTIONAL PROPERTIES;

BIOCHEMISTRY;

5' DEOXY 5' FLUOROURIDINE; ABC TRANSPORTER; ADEFOVIR; DOXORUBICIN; ETOPOSIDE; FLOXURIDINE; FLUOROPYRIMIDINE DERIVATIVE; FLUOROURACIL; FORSKOLIN; LAMIVUDINE; N MORPHOLINO N NITROSAMINOACETONITRILE; PACLITAXEL; PENTOSTATIN; PROTEIN MRP8; TIOGUANINE; UNCLASSIFIED DRUG; VINCRISTINE; ZALCITABINE; ZIDOVUDINE;

ANIMAL CELL; ANION TRANSPORT; ARTICLE; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG TRANSPORT; GENE OVEREXPRESSION; MEMBRANE VESICLE; MULTIDRUG RESISTANCE; NONHUMAN; NUCLEOTIDE TRANSPORT; PRIORITY JOURNAL; PROTEIN DETERMINATION; SWINE;

ANIMALIA; HUMAN IMMUNODEFICIENCY VIRUS; SUS SCROFA;

EID: 0042531890     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M304059200     Document Type: Article

References (44)

1. Goldenbaum, P. E., and Hall, G. A. (1979) J. Bacteriol. 140, 459-467
2. Brunton, L. L., and Heasley, L. E. (1988) Methods Enzymol. 159, 83-93
3. Brunton, L. L., and Mayer, S. E. (1979) J. Biol. Chem. 254, 9714-9720
4. Saier, M. H., Jr., Feucht, B. U., and McCaman, M. T. (1975) J. Biol. Chem. 250, 7593-7601
5. Janssens, P. M., and Van Haastert, P. J. (1987) Microbiol. Rev. 51, 396-418
6. Heasley, L. E., Azari, J., and Brunton, L. L. (1985) Mol Pharmacol. 27, 60-65
7. Steinberg, R. A., Steinberg, M. G., and van Daalen Wetters, T. (1979) J. Cell. Physiol. 100, 579-588
8. Billiar, T. R., Curran, R. D., Harbrecht, B. G., Stadler, J., Williams, D. L., Ochoa, J. B., Di Silvio, M., Simmons, R. L., and Murray, S. A. (1992) Am. J. Physiol. 262, C1077-C1082
9. Patel, M. J., Wypij, D. M., Rose, D. A., Rimele, T. J., and Wiseman, J. S. (1995) J. Pharmacol. Exp. Ther. 273, 16-25
10. Woods, M., and Houslay, M. D. (1991) Biochem. Pharmacol. 41, 385-394
11. Hamet, P., Pang, S. C., and Tremblay, J. (1989) J. Biol. Chem. 264, 12364-12369
12. Podevin, R. A., Boumendil-Podevin, E. F., Bujoli-Roche, J., and Priol, C. (1980) Biochim Biophys Acta 629, 135-142
13. Fehr, T. F., Dickinson, E. S., Goldman, S. J., and Slakey, L. L. (1990) J. Biol. Chem. 265, 10974-10980
14. Strewler, G. J. (1984) Am. J. Physiol. 246, C224-C230
15. Millul, V., Prie, D., Geniteau-Legendre, M., Verpont, M. C., Baudouin, B., and Ronco, P. M. (1996) Am. J. Physiol. 270, C1051-C1060
16. Schultz, C., Vaskinn, S., Kildalsen, H., and Sager, G. (1998) Biochemistry 37, 1161-1166
17. Kruh, G. D., Zeng, H., Rea, P. A., Liu, G., Chen, Z.-S., Lee, K., and Belinsky, M. G. (2001) J. Bioenerg. Biomembr. 33, 493-501
18. Jedlitschky, G., Burchell, B., and Keppler, D. (2000) J. Biol. Chem. 275, 30069-30074
19. Chen, Z.-S., Lee, K., and Kruh, G. D. (2001) J. Biol. Chem. 276, 33747-33754
20. van Aubel, R. A., Smeets, P. H., Peters, J. G., Bindels, R. J., and Russel, F. G. (2002) J. Am. Soc. Nephrol. 13, 595-603
21. Lee, K., Klein-Szanto, A. J., and Kruh, G. D. (2000) J. Natl. Cancer Inst. 92, 1934-1940
22. Chen, Z.-S., Lee, K., Walther, S., Blartchard Raftogianis, R., Kuwano, M., Zeng, H., and Kruh, G. D. (2002) Cancer Res. 62, 3144-3150
23. Zelcer, N., Reid, G., Wielinga, P., Kuil, A., Van Der Heijden, I., Schuetz, J. D., and Borst, P. (2003) Biochem. J. 371, 361-367
24. Schuetz, J. D., Connelly, M. C., Sun, D., Paibir, S. G., Flynn, P. M., Srinivas, R. V., Kumar, A., and Fridland, A. (1999) Nat. Med. 5, 1048-1051
25. Wijnholds, J., Mol, C. A., van Deemter, L., de Haas, M., Scheffer, G. L., Baas, F., Beijnen, J. H., Scheper, R. J., Hatse, S., De Clercq, E., Balzarini, J., and Borst, P. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 7476-7481
26. Bera, T. K., Lee, S., Salvatore, G., Lee, B., and Pastan, I. H. (2001) Mol. Med. 7, 509-516
27. Tammur, J., Prades, C., Arnould, I., Rzhetsky, A., Hutchinson, A., Adachi, M., Schuetz, J. D., Swoboda, K. J., Pracek, L. J., Rosier, M., Dean, M., and Allikmets, R. (2001) Gene 273, 89-96
28. Yabuuchi, H., Shimizu, H., Takayanagi, S., and Ishikawa, T. (2001) Biochem. Biophys. Res. Commun. 288, 933-939
29. Laemmli, U. K. (1970) Nature 227, 680-685
30. Towbin, H., Staehelin, T., and Gordon, J. (1979) Proc. Natl. Acad. Sci. U. S. A. 76, 4350-4354
31. Cornwell, M. M., Gottesman, M. M., and Pastan, I. H. (1986) J. Biol. Chem. 261, 7921-7928
32. Leier, I., Jedlitschky, G., Buchholz, U., Cole, S. P., Deeley, R. G., and Keppler, D. (1994) J. Biol. Chem. 269, 27807-27810
33. Starrett, J. E., Jr., Tortolani, D. R., Russell, J., Hitchcock, M. J., Whiterock, V., Martin, J. C., and Mansuri, M. M. (1994) J. Med. Chem. 37, 1857-1864
34. Lai, L., and Tan, T. M. (2002) Biochem. J. 361, 497-503
35. Wielinga, P. R., Van Der Heijden, I., Reid, G., Beijnen, J. H., Wijnholds, J., and Borst, P. (2003) J. Biol. Chem. 278, 17664-17671
36. Copur, S., Aiba, K., Drake, J. C., Allegra, C. J., and Chu, E. (1995) Biochem. Pharmacol. 49, 1419-1426
37. Johnston, P. G., Lenz, H. J., Leichman, C. G., Danenberg, K. D., Allegra, C. J., Danenberg, P. V., and Leichman, L. (1995) Cancer Res. 55, 1407-1412
38. Lenz, H. J., Leichman, C. G., Danenberg, K. D., Danenberg, P. V., Groshen, S., Cohen, H., Laine, L., Crookes, P., Silberman, H., Baranda, J., Garcia, Y., Li, J., and Leichman, L. (1996) J. Clin. Oncol. 14, 176-182
39. Lenz, H. J., Hayashi, K., Salonga, D., Danenberg, K. D., Danenberg, P. V., Metzger, R., Banerjee, D., Bertino, J. R., Groshen, S., Leichman, L. P., and Leichman, C. G. (1998) Clin. Cancer Res. 4, 1243-1250
40. Leichman, C. G., Lenz, H. J., Leichman, L., Danenberg, K., Baranda, J., Groshen, S., Boswell, W., Metzger, R., Tan, M., and Danenberg, P. V. (1997) J. Clin. Oncol. 15, 3223-3229
41. Ladner, R. D., Lynch, F. J., Groshen, S., Xiong, Y. P., Sherrod, A., Caradonna, S. J., Stoehlmacher, J., and Lenz, H. J. (2000) Cancer Res. 60, 3493-3503
42. Wielinga, P. R., Reid, G., Challa, E. E., van der Heijden, I., van Deemter, L., de Haas, M., Mol, C., Kuil, A. J., Groeneveld, E., Schuetz, J. D., Brouwer, C., De Abreu, R. A., Wijnholds, J., Beijnen, J. H., and Borst, P. (2002) Mol. Pharmacol. 62, 1321-1331
43. Fitzgibbon, J. E., Howell, R. M., Haberzettl, C. A., Sperber, S. J., Gocke, D. J., and Dubin, D. T. (1992) Antimicrob. Agents Chemother. 36, 153-157
44. Wang, X., Furukawa, T., Nitanda, T., Okamoto, M., Sugimoto, Y., Akiyama, S., and Baba, M. (2003) Mol. Pharmacol. 63, 65-72