메뉴 건너뛰기




Volumn 59, Issue 16, 1999, Pages 3998-4003

Enhancement of antibody-directed enzyme prodrug therapy in colorectal xenografts by an antivascular agent

Author keywords

[No Author keywords available]

Indexed keywords

5,6 DIMETHYLXANTHENONE 4 ACETIC ACID; CARBOXYPEPTIDASE G2; CARCINOEMBRYONIC ANTIGEN MONOCLONAL ANTIBODY; N [4 [(2 CHLOROETHYL)(2 MESYLOXYETHYL)AMINO]BENZOYL]GLUTAMIC ACID; PRODRUG;

EID: 0033567097     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (68)

References (29)
  • 1
    • 0024505574 scopus 로고
    • Delivery of novel therapeutic agents in tumors: Physiological barriers and strategies
    • Jain, R. K. Delivery of novel therapeutic agents in tumors: physiological barriers and strategies. J. Natl. Cancer Inst., 81: 570-576, 1989.
    • (1989) J. Natl. Cancer Inst. , vol.81 , pp. 570-576
    • Jain, R.K.1
  • 2
    • 0029785102 scopus 로고    scopus 로고
    • Pharmacokinetics of monoclonal antibodies: Implications for their use in cancer therapy
    • Pedley, R. B. Pharmacokinetics of monoclonal antibodies: implications for their use in cancer therapy. Clin. Immunother., 6: 54-67, 1996.
    • (1996) Clin. Immunother. , vol.6 , pp. 54-67
    • Pedley, R.B.1
  • 3
    • 0030020857 scopus 로고    scopus 로고
    • Pharmacokinetic analysis of the microscopic distribution of enzyme-conjugated antibodies and prodrugs: Comparison with experimental data
    • Baxter, L. T., and Jain, R. K. Pharmacokinetic analysis of the microscopic distribution of enzyme-conjugated antibodies and prodrugs: comparison with experimental data. Br. J. Cancer, 73: 447-456, 1996.
    • (1996) Br. J. Cancer , vol.73 , pp. 447-456
    • Baxter, L.T.1    Jain, R.K.2
  • 4
    • 0023619243 scopus 로고
    • Antibody directed enzymes revive anti-cancer prodrugs concept
    • Bagshawe, K. D. Antibody directed enzymes revive anti-cancer prodrugs concept. Br. J. Cancer, 56: 531-532, 1987.
    • (1987) Br. J. Cancer , vol.56 , pp. 531-532
    • Bagshawe, K.D.1
  • 6
    • 0028972656 scopus 로고
    • Antibody-directed enzyme prodrug therapy (ADEPT): A targeting strategy in cancer chemotherapy
    • Niculescu-Duvaz, I., and Springer, C. J. Antibody-directed enzyme prodrug therapy (ADEPT): a targeting strategy in cancer chemotherapy. Curr. Med. Chem., 2: 687-706, 1995.
    • (1995) Curr. Med. Chem. , vol.2 , pp. 687-706
    • Niculescu-Duvaz, I.1    Springer, C.J.2
  • 7
    • 0028122014 scopus 로고
    • Novel prodrugs of alkylating agents derived from 2-fluoro-and 3-fluorobenzoic acids for antibody-directed enzyme prodrug therapy
    • Springer, C. J., Niculescu-Duvaz, I., and Pedley, R. B. Novel prodrugs of alkylating agents derived from 2-fluoro-and 3-fluorobenzoic acids for antibody-directed enzyme prodrug therapy. J. Med. Chem., 37: 2361-2370, 1994.
    • (1994) J. Med. Chem. , vol.37 , pp. 2361-2370
    • Springer, C.J.1    Niculescu-Duvaz, I.2    Pedley, R.B.3
  • 9
    • 0002726158 scopus 로고
    • Antibody directed enzyme prodrug therapy: A pilot-scale clinical trial
    • Bagshawe, K. D. Sharma, S. K., Springer, C. J., and Antoniw, P. Antibody directed enzyme prodrug therapy: a pilot-scale clinical trial. Tumor Targeting, I: 17-29, 1995.
    • (1995) Tumor Targeting , vol.1 , pp. 17-29
    • Bagshawe, K.D.1    Sharma, S.K.2    Springer, C.J.3    Antoniw, P.4
  • 10
    • 0030971014 scopus 로고    scopus 로고
    • Antibody-directed enzyme prodrug therapy: Pharmacokinetics and plasma levels of prodrug and drug in a phase I clinical trial
    • Martin, J., Stribbling, S. M., Poon, G. K., Begent, R. H. J., Napier, M., Sharma, S. K., and Springer, C. J. Antibody-directed enzyme prodrug therapy: pharmacokinetics and plasma levels of prodrug and drug in a Phase I clinical trial. Cancer Chemother. Pharmacol., 40: 189-201, 1997.
    • (1997) Cancer Chemother. Pharmacol. , vol.40 , pp. 189-201
    • Martin, J.1    Stribbling, S.M.2    Poon, G.K.3    Begent, R.H.J.4    Napier, M.5    Sharma, S.K.6    Springer, C.J.7
  • 11
    • 0030951899 scopus 로고    scopus 로고
    • Combretastatin A-4, an agent that displays potent and selective toxicity toward tumor vasculature
    • Dark, G. G., Hill, S. A., Prise, V. E., Tozer, G. M., Pettit, G. R., and Chaplin, D. J. Combretastatin A-4, an agent that displays potent and selective toxicity toward tumor vasculature. Cancer Res., 57: 1829-1834, 1997.
    • (1997) Cancer Res. , vol.57 , pp. 1829-1834
    • Dark, G.G.1    Hill, S.A.2    Prise, V.E.3    Tozer, G.M.4    Pettit, G.R.5    Chaplin, D.J.6
  • 12
    • 0028412770 scopus 로고
    • The morphological effects of the anti-tumour agents flavone acetic acid and 5,6-dimethyl xanthenone acetic acid on colon 38 mouse tumour
    • Zwi, L. J., Baguley, B. C., Gavin, J. B., and Wilson, W. R. The morphological effects of the anti-tumour agents flavone acetic acid and 5,6-dimethyl xanthenone acetic acid on colon 38 mouse tumour. Pathology, 24: 161-169, 1994.
    • (1994) Pathology , vol.24 , pp. 161-169
    • Zwi, L.J.1    Baguley, B.C.2    Gavin, J.B.3    Wilson, W.R.4
  • 13
    • 0028263706 scopus 로고
    • Enhancement of radioimmunotherapy by drugs modifying tumour blood flow in a colonie xenograft model
    • Pedley, R. B., Begent, R. H. J., Boden, J. A., Boxer, G. M., Boden, R., and Keep, P.A. Enhancement of radioimmunotherapy by drugs modifying tumour blood flow in a colonie xenograft model. Int. J. Cancer, 57: 830-835, 1994.
    • (1994) Int. J. Cancer , vol.57 , pp. 830-835
    • Pedley, R.B.1    Begent, R.H.J.2    Boden, J.A.3    Boxer, G.M.4    Boden, R.5    Keep, P.A.6
  • 14
    • 0030002174 scopus 로고    scopus 로고
    • Ablation of colorectal xenografts with combined radioimmunotherapy and tumor blood flow modifying agents
    • Pedley, R. B., Boden, J. A., Boden, R., Boxer, G. M., Flynn, A. A., Keep, P. A., and Begent, R. H. J. Ablation of colorectal xenografts with combined radioimmunotherapy and tumor blood flow modifying agents. Cancer Res., 56: 3293-3300, 1996.
    • (1996) Cancer Res. , vol.56 , pp. 3293-3300
    • Pedley, R.B.1    Boden, J.A.2    Boden, R.3    Boxer, G.M.4    Flynn, A.A.5    Keep, P.A.6    Begent, R.H.J.7
  • 15
    • 0028280239 scopus 로고
    • Induction of tumour necrosis factor-α in human and murine cells by the flavone acetic acid analogue 5,6-dimethyhanthenone-4-acetic acid
    • Ching, L-M., Joseph, W. R., Crosier, K. E., and Baguley, B. C. Induction of tumour necrosis factor-α in human and murine cells by the flavone acetic acid analogue 5,6-dimethyhanthenone-4-acetic acid. Cancer Res., 54: 870-872, 1994.
    • (1994) Cancer Res. , vol.54 , pp. 870-872
    • Ching, L.-M.1    Joseph, W.R.2    Crosier, K.E.3    Baguley, B.C.4
  • 16
    • 0025189891 scopus 로고
    • Novel prodrugs which are activated to cytotoxic alkylating agents by carboxypeptidase G2
    • Springer, C. J., Antoniw, P., Bagshawe, K. D., Searle, F., Bisset, M. F., and Jarman, M. Novel prodrugs which are activated to cytotoxic alkylating agents by carboxypeptidase G2. J. Med. Chem., 33: 677-681, 1990.
    • (1990) J. Med. Chem. , vol.33 , pp. 677-681
    • Springer, C.J.1    Antoniw, P.2    Bagshawe, K.D.3    Searle, F.4    Bisset, M.F.5    Jarman, M.6
  • 17
    • 0027958916 scopus 로고
    • Radioimmunotherapy of metastatic colorectal tumours with iodine-131-labelled antibody to carcinoembryonic antigen: Phase I/II study with comparative biodistribution of intact and F(ab′)2 antibodies
    • Lane, D. M., Eagle, K. F., Begent, R. H. J., Hope-Stone, L. D., Green, A. J., Casey, J. L., Keep, P. A., Kelly, A. M. B., Ledermann, J. A., Glaser, M. G., and Hilson, A. J. W. Radioimmunotherapy of metastatic colorectal tumours with iodine-131-labelled antibody to carcinoembryonic antigen: Phase I/II study with comparative biodistribution of intact and F(ab′)2 antibodies. Br. J. Cancer, 70: 521-525, 1994.
    • (1994) Br. J. Cancer , vol.70 , pp. 521-525
    • Lane, D.M.1    Eagle, K.F.2    Begent, R.H.J.3    Hope-Stone, L.D.4    Green, A.J.5    Casey, J.L.6    Keep, P.A.7    Kelly, A.M.B.8    Ledermann, J.A.9    Glaser, M.G.10    Hilson, A.J.W.11
  • 19
    • 0021871027 scopus 로고
    • Purification and properties of carboxypeptidase G2 from Pseudomonas sp. strain RS16: Use of a novel triazine dye affinity method
    • Sherwood, R. F., Melton, R. G., Alwan, S. M., and Hughes, P. Purification and properties of carboxypeptidase G2 from Pseudomonas sp. strain RS16: use of a novel triazine dye affinity method. Eur. J. Biochem., 148: 447-453, 1985.
    • (1985) Eur. J. Biochem. , vol.148 , pp. 447-453
    • Sherwood, R.F.1    Melton, R.G.2    Alwan, S.M.3    Hughes, P.4
  • 21
    • 0030971725 scopus 로고    scopus 로고
    • Biodistribution of an antibody-enzyme conjugate for antibody-directed enzyme prodrug therapy in nude mice bearing a human colon adenocarcinoma xenograft. Cancer chemother
    • Stribbling, S. M., Martin, J., Pedley, R. B., Boden, J. A., Sharma, S. K., and Springer, C. J. Biodistribution of an antibody-enzyme conjugate for antibody-directed enzyme prodrug therapy in nude mice bearing a human colon adenocarcinoma xenograft. Cancer Chemother. Pharmacol., 40: 277-284, 1997.
    • (1997) Pharmacol. , vol.40 , pp. 277-284
    • Stribbling, S.M.1    Martin, J.2    Pedley, R.B.3    Boden, J.A.4    Sharma, S.K.5    Springer, C.J.6
  • 22
    • 0015608840 scopus 로고
    • A mathematical evaluation of tumour growth curves in rapid, intermediate and slow growing rat hepatoma
    • Looney, W. B., Mayo, A. A., Allen, P. M., Morrow, J. Y., and Morris, H. P. A mathematical evaluation of tumour growth curves in rapid, intermediate and slow growing rat hepatoma. Br. J. Cancer, 27: 341-344, 1973.
    • (1973) Br. J. Cancer , vol.27 , pp. 341-344
    • Looney, W.B.1    Mayo, A.A.2    Allen, P.M.3    Morrow, J.Y.4    Morris, H.P.5
  • 23
    • 0015432336 scopus 로고
    • A computer program for comparing K samples with right censored data
    • Lee, E., and Desu, M. A computer program for comparing K samples with right censored data. Comput. Prog. Biomed., 2: 315-321, 1972.
    • (1972) Comput. Prog. Biomed. , vol.2 , pp. 315-321
    • Lee, E.1    Desu, M.2
  • 24
    • 0032956678 scopus 로고    scopus 로고
    • A novel technique, using radioluminography, for the measurement of uniformity of radiolabeled antibody distribution on a colorectal cancer xenograft model
    • Flynn, A. A., Green, A. J., Boxer, G. M., Casey, J., Pedley, R. B., and Begent, R. H. J. A novel technique, using radioluminography, for the measurement of uniformity of radiolabeled antibody distribution on a colorectal cancer xenograft model. Int. J. Radiat. Oncol. Biol. Phys., 43: 183-189, 1999.
    • (1999) Int. J. Radiat. Oncol. Biol. Phys. , vol.43 , pp. 183-189
    • Flynn, A.A.1    Green, A.J.2    Boxer, G.M.3    Casey, J.4    Pedley, R.B.5    Begent, R.H.J.6
  • 27
    • 0031016945 scopus 로고    scopus 로고
    • Mechanisms of enhancement of the antitumour activity of melphalan by the tumour-blood-flow inhibitor 5,6-dimethylxanthenone-4-acetic acid
    • Pruijn, F. B., van Dalen, M., Holford, N. H. G., and Wilson, W. R. Mechanisms of enhancement of the antitumour activity of melphalan by the tumour-blood-flow inhibitor 5,6-dimethylxanthenone-4-acetic acid. Cancer Chemother. Pharmacol., 39: 541-546, 1997.
    • (1997) Cancer Chemother. Pharmacol. , vol.39 , pp. 541-546
    • Pruijn, F.B.1    Van Dalen, M.2    Holford, N.H.G.3    Wilson, W.R.4
  • 28
    • 0023676391 scopus 로고
    • Anti-tumour effects of tumour necrosis factor alone or combined with radiotherapy
    • Sersa, G., Willingham, V., and Milas, L. Anti-tumour effects of tumour necrosis factor alone or combined with radiotherapy. Int. J. Cancer, 42: 129-134, 1988.
    • (1988) Int. J. Cancer , vol.42 , pp. 129-134
    • Sersa, G.1    Willingham, V.2    Milas, L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.