Hepatic cytochrome P450 3A drug metabolism is reduced in cancer patients who have an acute-phase response

British Journal of Cancer

Volumn 87, Issue 3, 2002, Pages 277-280

  Rivory, L P ^a,b   Slaviero, K A ^b   Clarke, S J ^a  

^a SYDNEY CANCER CENTRE   (Australia)

^b University of Sydney   (Australia)

Author keywords

Acute phase response; Drug metabolism; Erythromycin breath test (EBT)

Indexed keywords

ANTINEOPLASTIC AGENT; C REACTIVE PROTEIN; CLARITHROMYCIN; CYTOCHROME P450 3A; DILTIAZEM; ERYTHROMYCIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; TUMOR NECROSIS FACTOR ALPHA;

ACUTE PHASE RESPONSE; ADULT; ADVANCED CANCER; AGED; ARTHRITIS; ARTICLE; BREATH ANALYSIS; CANCER PATIENT; CLINICAL ARTICLE; CORRELATION ANALYSIS; DRUG METABOLISM; DRUG OXIDATION; FEMALE; HUMAN; INFECTION; INFLAMMATION; MALE; MALIGNANT NEOPLASTIC DISEASE; PRIORITY JOURNAL;

ACUTE-PHASE PROTEINS; ADULT; AGED; AGED, 80 AND OVER; ARYL HYDROCARBON HYDROXYLASES; C-REACTIVE PROTEIN; CYTOCHROME P-450 CYP3A; CYTOCHROME P-450 ENZYME SYSTEM; CYTOKINES; FEMALE; HUMANS; LIVER; MALE; MIDDLE AGED; NEOPLASMS; OROSOMUCOID; OXIDOREDUCTASES, N-DEMETHYLATING; PROSPECTIVE STUDIES;

EID: 0037194409     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjc.6600448     Document Type: Article

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