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Volumn 4, Issue 10, 1998, Pages 2371-2376

High basal level gene expression of thymidine phosphorylase (platelet- derived endothelial cell growth factor) in colorectal tumors is associated with nonresponse to 5-fluorouracil

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; COMPLEMENTARY DNA; FLUOROURACIL; IRINOTECAN; LEVULINIC ACID; MESSENGER RNA; PLATELET DERIVED ENDOTHELIAL CELL GROWTH FACTOR; THYMIDINE PHOSPHORYLASE;

EID: 0031722179     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (248)

References (46)
  • 1
    • 77049164570 scopus 로고
    • The enzymatic synthesis of nucleosides
    • Friedkin, D., and Roberts, D. The enzymatic synthesis of nucleosides. J. Biol. Chem., 207: 245-256, 1954.
    • (1954) J. Biol. Chem. , vol.207 , pp. 245-256
    • Friedkin, D.1    Roberts, D.2
  • 2
    • 0022345955 scopus 로고
    • Kinetic studies of thymidine phosphorylase
    • Iltzsch, M. H., el Kouni, M. H., and Cha, S. Kinetic studies of thymidine phosphorylase. Biochemistry, 24: 6799-6807, 1985.
    • (1985) Biochemistry , vol.24 , pp. 6799-6807
    • Iltzsch, M.H.1    El Kouni, M.H.2    Cha, S.3
  • 3
    • 78651153400 scopus 로고
    • Deoxyribosyl transfer. I. Thymidine phosphorylase and nucleoside deoxyribosyltransferase in normal and malignant tissues
    • Zimmerman, M., and Seidenberg, J. Deoxyribosyl transfer. I. Thymidine phosphorylase and nucleoside deoxyribosyltransferase in normal and malignant tissues. J. Biol. Chem., 230: 2618-2621, 1964.
    • (1964) J. Biol. Chem. , vol.230 , pp. 2618-2621
    • Zimmerman, M.1    Seidenberg, J.2
  • 4
    • 0029821907 scopus 로고    scopus 로고
    • Expression of the angiogenic factor thymidine phosphorylase/platelet-derived endothelial cell growth factor in primary bladder cancers
    • O'Brien, T. S., Fox, S. B., Dickinson, A. J., Turley, H., Westwood, M., Moghaddam, A., Gatter, K. C., Bicknell, R., and Harris, A. L. Expression of the angiogenic factor thymidine phosphorylase/platelet-derived endothelial cell growth factor in primary bladder cancers. Cancer Res., 56: 4799-4804, 1996.
    • (1996) Cancer Res. , vol.56 , pp. 4799-4804
    • O'Brien, T.S.1    Fox, S.B.2    Dickinson, A.J.3    Turley, H.4    Westwood, M.5    Moghaddam, A.6    Gatter, K.C.7    Bicknell, R.8    Harris, A.L.9
  • 5
    • 0027053205 scopus 로고
    • Human platelet-derived endothelial cell growth factor is homologous to Escherichia coli thymidine phosphorylase
    • Barton, G. J., Ponting, C. P., Spraggon, C., Finnis, C., and Sleep, D. Human platelet-derived endothelial cell growth factor is homologous to Escherichia coli thymidine phosphorylase. Prot. Sci., 1: 688-690, 1992.
    • (1992) Prot. Sci. , vol.1 , pp. 688-690
    • Barton, G.J.1    Ponting, C.P.2    Spraggon, C.3    Finnis, C.4    Sleep, D.5
  • 7
    • 0026690144 scopus 로고
    • Expression of platelet-derived endothelial cell growth factor in Escherichia coli and confirmation of its thymidine phosphorylase activity
    • Moghaddam, M. H., and Bicknell, R. Expression of platelet-derived endothelial cell growth factor in Escherichia coli and confirmation of its thymidine phosphorylase activity. Biochemistry, 31: 12141-12146, 1992.
    • (1992) Biochemistry , vol.31 , pp. 12141-12146
    • Moghaddam, M.H.1    Bicknell, R.2
  • 9
    • 0027530691 scopus 로고
    • Thymidine phosphorylase activity of platelet-derived endothelial cell growth factor is responsible for endothelial cell mitogenicity
    • Finnis, C., Dodsworth, N., Pollit, C. E., Carr, G., and Sleep, D. Thymidine phosphorylase activity of platelet-derived endothelial cell growth factor is responsible for endothelial cell mitogenicity. Eur. J. Biochem., 212: 201-210, 1993.
    • (1993) Eur. J. Biochem. , vol.212 , pp. 201-210
    • Finnis, C.1    Dodsworth, N.2    Pollit, C.E.3    Carr, G.4    Sleep, D.5
  • 13
    • 0028951104 scopus 로고
    • Expression of platelet-derived endothelial cell growth factor/thymidine phosphorylase in human breast cancer
    • Toi, M., Hoshina, S., Taniguchi, T., Yamamoto, Y., Ishitsuka, H., and Tominaga, T. Expression of platelet-derived endothelial cell growth factor/thymidine phosphorylase in human breast cancer. Int. J. Cancer, 64: 79-82, 1995.
    • (1995) Int. J. Cancer , vol.64 , pp. 79-82
    • Toi, M.1    Hoshina, S.2    Taniguchi, T.3    Yamamoto, Y.4    Ishitsuka, H.5    Tominaga, T.6
  • 14
    • 0029790296 scopus 로고    scopus 로고
    • Platelet-derived endothelial cell growth factor in human colon carcinogenesis: Role of infiltrating cells
    • Takahashi, Y., Bucana, C. D., Liu, W., Yoneda, J., Clearly, K. R., and Ellis, L. M. Platelet-derived endothelial cell growth factor in human colon carcinogenesis: role of infiltrating cells. J. Natl. Cancer Inst., 88: 1146-1151, 1996.
    • (1996) J. Natl. Cancer Inst. , vol.88 , pp. 1146-1151
    • Takahashi, Y.1    Bucana, C.D.2    Liu, W.3    Yoneda, J.4    Clearly, K.R.5    Ellis, L.M.6
  • 17
    • 0029997353 scopus 로고    scopus 로고
    • Thymidine phosphorylase/platelet-derived endothelial cell growth factor expression associated with hepatic metastasis in gastric carcinoma
    • Maeda, K., Chung, Y. S., Ogawa, Y., Takatsuka, S., Kang, S. M., Ogawa, M., Sawada, T., Onoda, N., Kato, Y., and Sowa, M. Thymidine phosphorylase/platelet-derived endothelial cell growth factor expression associated with hepatic metastasis in gastric carcinoma. Br. J. Cancer, 73: 884-888, 1996.
    • (1996) Br. J. Cancer , vol.73 , pp. 884-888
    • Maeda, K.1    Chung, Y.S.2    Ogawa, Y.3    Takatsuka, S.4    Kang, S.M.5    Ogawa, M.6    Sawada, T.7    Onoda, N.8    Kato, Y.9    Sowa, M.10
  • 20
    • 0028957177 scopus 로고
    • Role of thymidine phosphorylase activity in the angiogenic effect of platelet-derived endothelial cell growth factor/thymidine phosphorylase
    • Miyadera, K., Sumizawa, T., Haraguchi, M., Yoshida, H., Konstanty, W., Yamada, Y., and Akiyama, S. Role of thymidine phosphorylase activity in the angiogenic effect of platelet-derived endothelial cell growth factor/thymidine phosphorylase. Cancer Res., 55: 1687-1690, 1995.
    • (1995) Cancer Res. , vol.55 , pp. 1687-1690
    • Miyadera, K.1    Sumizawa, T.2    Haraguchi, M.3    Yoshida, H.4    Konstanty, W.5    Yamada, Y.6    Akiyama, S.7
  • 21
    • 2042544213 scopus 로고
    • Studies of fluorinated pyrimidines. XVIII. The degradation of 5-fluoro-2′-deoxyuridine and related compounds by nucleoside phosphorylase
    • Birnie, G. D., Kroeger, H., and Heidelberger, C. Studies of fluorinated pyrimidines. XVIII. The degradation of 5-fluoro-2′-deoxyuridine and related compounds by nucleoside phosphorylase. Biochemistry, 2: 566-572, 1963.
    • (1963) Biochemistry , vol.2 , pp. 566-572
    • Birnie, G.D.1    Kroeger, H.2    Heidelberger, C.3
  • 22
    • 0014783519 scopus 로고
    • Irreversible enzyme inhibitors. CLXXI. Inhibition of FUDR phosphorylase from Walker 256 rat tumor by 6-substituted uracils
    • Baker, B. R., and Kelley, J. L. Irreversible enzyme inhibitors. CLXXI. Inhibition of FUDR phosphorylase from Walker 256 rat tumor by 6-substituted uracils. J. Med. Chem., 13: 461-467, 1970.
    • (1970) J. Med. Chem. , vol.13 , pp. 461-467
    • Baker, B.R.1    Kelley, J.L.2
  • 23
    • 0018916975 scopus 로고
    • In vivo potentiation of 5-fluorouracil toxicity against AKR leukemia by purines, pyrimidines, and their nucleosides and deoxynucleosides
    • Santelli, G., and Birnie, F. In vivo potentiation of 5-fluorouracil toxicity against AKR leukemia by purines, pyrimidines, and their nucleosides and deoxynucleosides. J. Natl. Cancer Inst., 64: 69-72, 1980.
    • (1980) J. Natl. Cancer Inst. , vol.64 , pp. 69-72
    • Santelli, G.1    Birnie, F.2
  • 24
    • 3543101363 scopus 로고
    • Effect of folates and deoxyinosine on the activity and site of action of 5-fluorouracil
    • Evans, R. M., Laskin, J. D., and Hakala, M. T. Effect of folates and deoxyinosine on the activity and site of action of 5-fluorouracil. Cancer Res., 29: 807-811, 1981.
    • (1981) Cancer Res. , vol.29 , pp. 807-811
    • Evans, R.M.1    Laskin, J.D.2    Hakala, M.T.3
  • 25
    • 0029051690 scopus 로고
    • Thymidine phosphorylase mediates the sensitivity of colon carcinoma cells to 5-fluorouracil
    • Schwartz, E. L., Baptiste, N., Wadler, S., and Makower, D. Thymidine phosphorylase mediates the sensitivity of colon carcinoma cells to 5-fluorouracil. J. Biol. Chem., 270: 19073-19077, 1995.
    • (1995) J. Biol. Chem. , vol.270 , pp. 19073-19077
    • Schwartz, E.L.1    Baptiste, N.2    Wadler, S.3    Makower, D.4
  • 26
    • 0031056806 scopus 로고    scopus 로고
    • Enhancement of drug sensitivity and a bystander effect in PC-9 cells transfected with a platelet-derived endothelial cell growth factor thymidine phosphorylase cDNA
    • Kato, Y., Matsukawa, S., Muraoka, R., and Tanigawa, N. Enhancement of drug sensitivity and a bystander effect in PC-9 cells transfected with a platelet-derived endothelial cell growth factor thymidine phosphorylase cDNA. Br. J. Cancer. 75: 506-511, 1997.
    • (1997) Br. J. Cancer , vol.75 , pp. 506-511
    • Kato, Y.1    Matsukawa, S.2    Muraoka, R.3    Tanigawa, N.4
  • 27
    • 0026600296 scopus 로고
    • Stimulation of 5-fluorouracil metabolic activation by interferon-A in human colon carcinoma cells
    • Schwartz, E. L., Hoffman, M., O'Connor, C. J., and Wadler, S. Stimulation of 5-fluorouracil metabolic activation by interferon-A in human colon carcinoma cells. Biochem. Biophys. Res. Commun., 182: 1232-1239, 1992.
    • (1992) Biochem. Biophys. Res. Commun. , vol.182 , pp. 1232-1239
    • Schwartz, E.L.1    Hoffman, M.2    O'Connor, C.J.3    Wadler, S.4
  • 28
    • 0024414582 scopus 로고
    • Interferon effects upon fluorouracil metabolism by HL-60 cells
    • Elias, S., and Sandoval, J. M. Interferon effects upon fluorouracil metabolism by HL-60 cells. Biophys. Biochem. Res. Commun., 163: 867-874, 1989.
    • (1989) Biophys. Biochem. Res. Commun. , vol.163 , pp. 867-874
    • Elias, S.1    Sandoval, J.M.2
  • 29
    • 0027313603 scopus 로고
    • Cytokines induce thymidine phosphorylase expression in tumor cells and make them more susceptible to 5′-deoxy-5-fluorouridine
    • Eda, H., Fujimoto, K., Watanabe, S., Ura, M., Hino, A., Tanaka, Y., Wada, K., and Ishitsuka, H. Cytokines induce thymidine phosphorylase expression in tumor cells and make them more susceptible to 5′-deoxy-5-fluorouridine. Cancer Chemother. Pharmacol., 32: 333-338, 1993.
    • (1993) Cancer Chemother. Pharmacol. , vol.32 , pp. 333-338
    • Eda, H.1    Fujimoto, K.2    Watanabe, S.3    Ura, M.4    Hino, A.5    Tanaka, Y.6    Wada, K.7    Ishitsuka, H.8
  • 30
    • 0028018118 scopus 로고
    • Pyrimidine nucleotide metabolism in human colon carcinomas: Comparison of normal tissues, primary tumors and xenografts
    • Luccioni, C., Beaumatin, J., Bardot, V., and Lefrancois, D. Pyrimidine nucleotide metabolism in human colon carcinomas: comparison of normal tissues, primary tumors and xenografts. Int. J. Cancer, 58: 517-522, 1994.
    • (1994) Int. J. Cancer , vol.58 , pp. 517-522
    • Luccioni, C.1    Beaumatin, J.2    Bardot, V.3    Lefrancois, D.4
  • 31
    • 0029837638 scopus 로고    scopus 로고
    • What is the role of thymidine phosphorylase in tumor angiogenesis?
    • Folkman, J. What is the role of thymidine phosphorylase in tumor angiogenesis? J. Natl. Cancer Inst., 88: 1091-1092, 1996.
    • (1996) J. Natl. Cancer Inst. , vol.88 , pp. 1091-1092
    • Folkman, J.1
  • 32
    • 0030883708 scopus 로고    scopus 로고
    • Quantitation of intratumoral thymidylate synthase expression predicts for disseminated colorectal cancer response and resistance to protracted infusion 5-fluorouracil and weekly leucovorin
    • Leichman, C. G., Lenz, H-J., Leichman, L., Danenberg, K., Baranda, J., Groshen, S., Boswell, W., Metzger, R., Tan, M., and Danenberg, P. V. Quantitation of intratumoral thymidylate synthase expression predicts for disseminated colorectal cancer response and resistance to protracted infusion 5-fluorouracil and weekly leucovorin. J. Clin. Oncol., 75: 3223-3229, 1997.
    • (1997) J. Clin. Oncol. , vol.75 , pp. 3223-3229
    • Leichman, C.G.1    Lenz, H.-J.2    Leichman, L.3    Danenberg, K.4    Baranda, J.5    Groshen, S.6    Boswell, W.7    Metzger, R.8    Tan, M.9    Danenberg, P.V.10
  • 33
    • 0027408915 scopus 로고
    • Prolonged continuous infusion of fluorouracil with weekly bolus leucovorin: A phase II study in patients with disseminated gastrointestinal cancers
    • Leichman, C. G., Leichman, L., Spears, C. P., Rosen, P. J., Jeffers, S., and Groshen, S. Prolonged continuous infusion of fluorouracil with weekly bolus leucovorin: a phase II study in patients with disseminated gastrointestinal cancers. J. Natl. Cancer Inst., 85: 41-44, 1993.
    • (1993) J. Natl. Cancer Inst. , vol.85 , pp. 41-44
    • Leichman, C.G.1    Leichman, L.2    Spears, C.P.3    Rosen, P.J.4    Jeffers, S.5    Groshen, S.6
  • 34
    • 0027076295 scopus 로고
    • Southwest Oncology Group standard response criteria, endpoint definitions, and toxicity criteria
    • Green, S., and Weiss, G. R., Southwest Oncology Group standard response criteria, endpoint definitions, and toxicity criteria. Invest. New Drugs, 10: 239-253, 1992.
    • (1992) Invest. New Drugs , vol.10 , pp. 239-253
    • Green, S.1    Weiss, G.R.2
  • 37
    • 0028940399 scopus 로고
    • Thymidylate synthase gene and protein expression correlate and are associated with response to 5-fluorouracil in human colorectal and gastric tumors
    • Johnston, P. G., Lenz, H-J., Leichman, C. G., Danenberg, K. D., Allegra, C. J., Danenberg, P. V., and Leichman, L. Thymidylate synthase gene and protein expression correlate and are associated with response to 5-fluorouracil in human colorectal and gastric tumors. Cancer Res., 55: 1407-1412, 1995.
    • (1995) Cancer Res. , vol.55 , pp. 1407-1412
    • Johnston, P.G.1    Lenz, H.-J.2    Leichman, C.G.3    Danenberg, K.D.4    Allegra, C.J.5    Danenberg, P.V.6    Leichman, L.7
  • 39
    • 0028060451 scopus 로고
    • The relationship between an objective response to chemotherapy and survival in advanced colorectal cancer
    • Graf, W., Pählman, L., Bergström, R., and Glimelius, B. The relationship between an objective response to chemotherapy and survival in advanced colorectal cancer. Br. J. Cancer. 70: 559-563, 1994.
    • (1994) Br. J. Cancer , vol.70 , pp. 559-563
    • Graf, W.1    Pählman, L.2    Bergström, R.3    Glimelius, B.4
  • 41
    • 0029102247 scopus 로고
    • 5-Ethoxy-2′-deoxyuridine, a novel substrate for thymidine phosphorylase, potentiates the antitumor activity of 5-fluorouracil when used in combination with interferon, an inducer of thymidine phosphorylase expression
    • Schwartz, E. L., Baptiste, N., Megati, S., Wadler, S., and Otter, B. A. 5-Ethoxy-2′-deoxyuridine, a novel substrate for thymidine phosphorylase, potentiates the antitumor activity of 5-fluorouracil when used in combination with interferon, an inducer of thymidine phosphorylase expression. Cancer Res., 55: 3543-3550, 1995.
    • (1995) Cancer Res. , vol.55 , pp. 3543-3550
    • Schwartz, E.L.1    Baptiste, N.2    Megati, S.3    Wadler, S.4    Otter, B.A.5
  • 42
    • 0031023710 scopus 로고    scopus 로고
    • Spontaneous apoptosis is inversely related to intratumoral microvessel density in gastric carcinoma
    • Lu, C., and Tanigawa, N. Spontaneous apoptosis is inversely related to intratumoral microvessel density in gastric carcinoma. Cancer Res., 57: 221-224, 1997.
    • (1997) Cancer Res. , vol.57 , pp. 221-224
    • Lu, C.1    Tanigawa, N.2
  • 43
    • 0030576517 scopus 로고    scopus 로고
    • Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
    • Hanahan, D., and Folkman, J. Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell, 86: 353-364, 1996.
    • (1996) Cell , vol.86 , pp. 353-364
    • Hanahan, D.1    Folkman, J.2
  • 46
    • 0028018118 scopus 로고
    • Pyrimidine nucleoside metabolism in human colon carcinomas: Comparison of normal tissues, primary tumors and xenografts
    • Luccioni, C., Beaumatin, J., Bardot, V., and Lefrancois, D. Pyrimidine nucleoside metabolism in human colon carcinomas: comparison of normal tissues, primary tumors and xenografts. Int. J. Cancer, 58: 517-522, 1994.
    • (1994) Int. J. Cancer , vol.58 , pp. 517-522
    • Luccioni, C.1    Beaumatin, J.2    Bardot, V.3    Lefrancois, D.4


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