Multidrug resistance mediated by the breast cancer resistance protein BCRP (ABCG2)

Oncogene

Volumn 22, Issue 47 REV. ISS. 6, 2003, Pages 7340-7358

  Doyle, L Austin ^a,b   Ross, Douglas D ^a,b,c  

^a UNIVERSITY OF MARYLAND   (United States)

^b UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^c BALTIMORE VA MEDICAL CENTER   (United States)

Author keywords

ABC transporter; ABCG2; BCRP; Cancer; Drug resistance

Indexed keywords

6 FORMYLAMINO 12,13 DIHYDRO 1,11 DIHYDROXY 5H INDOLO[2,3 A]PYRROLO[3,4 C]CARBAZOLE 5,7(6H) DIONE 13 GLUCOSIDE; 7 ETHYL 10 HYDROXYCAMPTOTHECIN; 9 AMINOCAMPTOTHECIN; ANTHRACYCLINE DERIVATIVE; BBR 3390; BREAST CANCER RESISTANT PROTEIN; CANERTINIB; CARBAZOLE DERIVATIVE; CISPLATIN; DACTINOMYCIN; DAUNORUBICIN; DOXORUBICIN; ELACRIDAR; EPIRUBICIN; FLAVOPIRIDOL; GEFITINIB; GIMATECAN; IDARUBICINOL; IRINOTECAN; LAMIVUDINE; MELPHALAN; METHOTREXATE; MITOXANTRONE; PACLITAXEL; PRAZOSIN; PROTEIN; TARIQUIDAR; TENIPOSIDE; TOPOTECAN; UNCLASSIFIED DRUG; UNINDEXED DRUG; VALSPODAR; VINCA ALKALOID; ZIDOVUDINE; ZORUBICIN;

BRAIN; BREAST CANCER; CANCER RESISTANCE; CHROMOSOMAL LOCALIZATION; CHROMOSOME 4Q; CODON; COLON; DIMERIZATION; DOWNSTREAM PROCESSING; DRUG CONJUGATION; DRUG SENSITIVITY; DRUG TRANSPORT; EFFUSION; ENZYME SPECIFICITY; GENE CASSETTE; GENE FUNCTION; GENE IDENTIFICATION; GENE OVEREXPRESSION; GENE THERAPY; GENETIC TRANSFECTION; HUMAN; INTRAHEPATIC BILE DUCT; MICROVASCULATURE; MULTIDRUG RESISTANCE; NONHUMAN; PHENOTYPE; PLACENTA; PRIORITY JOURNAL; PROMOTER REGION; REVIEW; SMALL INTESTINE; STEM CELL; TISSUE DISTRIBUTION; XENOBIOTIC METABOLISM;

ANIMALS; ANTINEOPLASTIC AGENTS; ATP-BINDING CASSETTE TRANSPORTERS; BREAST NEOPLASMS; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; NEOPLASM PROTEINS; SUBSTRATE SPECIFICITY;

MINK CELL FOCUS-FORMING VIRUS; VINCA;

EID: 0345688604     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1206938     Document Type: Review

References (130)

1. Abbott BL, Colapietro AM, Barnes Y, Marini F, Andreeff M and Sorrentino BP. (2002). Blood, 100, 4594-4601.
2. Abele R and Tampe R. (1999). Biochim. Biophys. Acta, 1461, 405-419.
3. Allen JD, Brinkhuis RF, Wijnholds J and Schinkel AH. (1999). Cancer Res., 59, 4237-4241.
4. Allen JD, Jackson SC and Schinkel AH. (2002a). Cancer Res., 62, 2294-2299.
5. Allen JD, van Loevezijn A, Lakhai JM, van der Valk M, van Tellingen O, Reid G, Schellens JH, Koomen GJ and Schinkel AH. (2002b). Mol. Cancer Ther., 1, 417-425.
6. Allikmets R, Gerrard B, Hutchinson A and Dean M. (1996). Hum. Mol. Genet., 5, 1649-1655.
7. Allikmets R, Schriml LM, Hutchinson A, Romano-Spica V and Dean M. (1998). Cancer Res., 58, 5337-5339.
8. Baer MR, Suvannasankha A, O'Loughlin KL, Greco WR and Minderman H. (2002). Blood (Suppl.), 100, 67a (abstract 245).
9. Bailey-Dell KJ, Hassel B, Doyle LA and Ross DD. (2001). Biochim. Biophys. Acta, 1520, 234-241.
10. Bates SE, Robey R, Miyake K, Rao K, Ross DD and Litman T. (2001). J. Bioenerg. Biomembr., 33, 503-511.
11. Borst P, Evers R, Kool M and Wijnholds J. (1999). Biochim. Biophys. Acta, 1461, 347-357.
12. Brangi M, Litman T, Ciotti M, Nishiyama K, Kohlhagen G, Takimoto C, Robey R, Pommier Y, Fojo T and Bates SE. (1999). Cancer Res., 59, 5938-5946.
13. Bunting KD. (2002). Stem Cells, 20, 11-20.
14. Chen WS, Luker KE, Dahlheimer JL, Pica CM, Luker GD and Piwnica-Worms D. (2000). Biochem. Pharmacol., 60, 413-426.
15. Chen YN, Mickley LA, Schwartz AM, Acton EM, Hwang JL and Fojo AT. (1990). J. Biol. Chem., 265, 10073-10080.
16. Chen YN, Rossierickley c, Lalioti MD, Lynn A, Chakravarti A, Perrin G and Antonarakis SE. (1996). Am. J. Hum. Genet., 59, 66-75.
17. Cole SP, Bhardwaj G, Gerlach JH, Mackie JE, Grant CE, Almquist KC, Stewart AJ, Kurz EU, Duncan AM and Deeley RG. (1992). Science, 258, 1650-1654.
18. Cole RJ and Cox RH. (1981). In Handbook of Toxic Fungal Metabolites. New York, Academic Press. Tremorgen Group, 355-509.
19. Cooray HC, Blackmore CG, Maskell L and Barrand MA. (2002). Neuroreport, 13, 2059-2063.
20. Croop JM, Tiller GE, Fletcher JA, Lux ML, Raab E, Goldenson D, Son D, Arciniegas S and Wu RL. (1997). Gene, 185, 77-85.
21. de Bruin M, Miyake K, Litman T, Robey R and Bates SE. (1999). Cancer Lett., 146, 117-126.
22. Diestra JE, Scheffer GL, Catala II, Maliepaard M, Schellens JH, Scheper RJ, Germa-Lluch JR and Izquierdo MA. (2002). J Pathol., 198, 213-219.
23. Dietel M, Arps H, Lage H and Niendorf A. (1990). Cancer Res., 50, 6100-6106.
24. Doyle LA, Ross DD, Südhara R, Fojo AT, Kaufmann SH, Lee EJ and Scheffer CA. (1995). Br. J. Cancer, 71, 52-58.
25. Doyle LA, Yang W, Abruzzo LV, Krogmann T, Gao Y, Rishi AK and Ross DD. (1998). Proc. Natl. Acad. Sci. USA, 95, 15665-15670.
26. Doyle LA, Yang W, Gao Y, Ordonez JV and Ross DD. (1996). Proc. Am. Soc. Clin. Oncol., 15, 398.
27. Eisenblatter T and Galla HJ. (2002). Biochem. Biophys. Res. Commun., 293, 1273-1278.
28. Ejendal and Hrycyna CA. (2002). Curr. Protein Pept. Sci., 3, 503-511.
29. Elferink RO and Groen AK. (2002). Biochim. Biophys. Acta, 1586, 129-145.
30. Erlichman C, Boerner SA, Hallgren CG, Spieker R, Wang XY, James CD, Scheffer GL, Maliepaard M, Ross DD, Bible KC and Kaufmann SH. (2001). Cancer Res., 61, 739-748.
31. Ewart GD, Cannell D, Cox GB and Howells AJ. (1994). J. Biol. Chem., 269, 10370-10377.
32. Ewart GD and Howells AJ. (1998). Methods Enzymol., 292, 213-224.
33. Faneyte IF, Kristel PM, Maliepaard M, Scheffer GL, Scheper RJ, Schellens JH and van de Vijver MJ. (2002). Clin. Cancer Res., 8, 1068-1074.
34. Futscher BW, Abbaszadegan MR, Domann F and Dalton WS. (1994). Biochem. Pharmacol., 47, 1601-1606.
35. Goodell MA, Rosenzweig M, Kim H, Marks DF, DeMaria M, Paradis G, Grupp SA, Sieff CA, Mulligan RC and Johnson RP. (1997). Nat. Med., 3, 1337-1345.
36. Guo Y, Lubbert M and Engelhardt M. (2003). Stem Cells, 21, 15-20.
37. Hausner P, Venzon DJ, Grogan L and Kirsch IR. (1999). Neoplasia, 1, 356-367.
38. Hazlehurst LA, Foley NE, Gleason-Guzman MC, Hacker MP, Cress AE, Greenberger LW, De Jong MC and Dalton WS. (1999). Cancer Res., 59, 1021-1028.
39. Higgins CF. (1995). Cell, 82, 693-696.
40. Honjo Y, Hrycyna CA, Yan QW, Medina-Perez WY, Robey RW, van de Laar A, Litman T, Dean M and Bates SE. (2001a). Cancer Res., 61, 6635-6639.
41. Honjo Y, Robey R, Yan QW, Litman T, van de Laar A, Covitz M, Hrycyna C and Bates S. (2001b). Third FEBS Advanced Lecture Course on ATP-Binding Cassette (ABC) Proteins: From Multidrug Resistance to Genetic Diseases Gosau, Austria (abstract).
42. Honjo Y, Robey RW, Dean M, Hrycyna C and Bates SE. (2002). Proc. Am. Assoc. Cancer Res., 43, 778 (abstract 3858).
43. Imai Y, Nakane M, Kage K, Tsukahara S, Ishikawa E, Tsuruo T, Miki Y and Sugimoto Y. (2002a). Mol. Cancer Ther., 1, 611-616.
44. Imai Y, Tsukahara S, Ishikawa E, Tsuruo T and Sugimoto Y. (2002b). Jpn. J. Cancer Res., 93, 231-235.
45. Ishii M, Iwahana M, Mitsui I, Minami M, Imagawa S, Tohgo A and Ejima A. (2000). Anticancer Drugs, 11, 353-362.
46. Izquierdo MA, Diestra JE, Condom E, Scheffer GL and Germa-Lluch JP. (2002). Proc. Am. Assoc. Cancer Res., 43, 77 (abstract 3854).
47. Jonker JW, Buitelaar M, Wagenaar E, Van Der Valk MA, Scheffer GL, Scheper RJ, Plosch T, Kuipers F, Oude Elferink RP, Rosing H, Beijnen JH and Schinkel AH. (2002). Proc. Natl. Acad. Sci. USA, 12, 15649-15654.
48. Jonker JW, Smit JW, Brinkhuis RF, Maliepaard M, Beijnen JH, Schellens JH and Schinkel AH. (2000). J. Natl. Cancer Inst., 92, 1651-1656.
49. Juliano RL and Ling V. (1976). Biochim. Biophys. Acta, 455, 152-162.
50. Kage K, Tsukahara S, Sugiyama T, Asada S, Ishikawa E, Tsuruo T and Sugimoto Y. (2002). Int. J. Cancer, 97, 626-630.
51. Kanzaki A, Toi M, Nakayama K, Bando H, Mutoh M, Uchida T, Fukumoto M and Takebayashi Y. (2001). Jpn. J. Cancer Res., 92, 452-458.
52. Kawabata S, Oka M, Nakatomi K, Shiozawa K, Kasai T, Fukuda M, Soda H and Kohno S. (2001a). Proc. Am. Assoc. Cancer Res., 42, 930 (abstract 4995).
53. Kawabata S, Oka M, Shiozawa K, Tsukamoto K, Nakatomi K, Soda H, Fukuda M, Ikegami Y, Sugahara K, Yamada Y, Kamihira S, Doyle LA, Ross DD and Kohno S. (2001b). Biochem. Biophys. Res. Commun., 280, 1216-1223.
54. Kim M, Turnquist H, Jackson J, Sgagias M, Yan Y, Gong M, Dean M, Sharp JG and Cowan K. (2002). Clin. Cancer Res., 8, 22-28.
55. Klucken J, Buchler C, Orso E, Kaminski WE, Porsch-Ozcurumez M, Liebisch G, Kapinsky M, Diederich W, Drobnik W, Dean M, Allikmets R and Schmitz G. (2000). Proc. Natl. Acad. Sci. USA, 97, 817-822.
56. Knutsen T, Rao VK, Ried T, Mickley L, Schneider E, Miyake K, Ghadimi BM, Padilla-Nash H, Pack S, Greenberger L, Cowan K, Dean M, Fojo T and Bates S. (2000). Genes Chromosomes Cancer, 27, 110-116.
57. Komatani H, Kotani H, Hara Y, Nakagawa R, Matsumoto M, Arakawa H and Nishimura S. (2001). Cancer Res., 61, 2827-2832.
58. Kowalski P, Stein U, Scheffer GL and Lage H. (2002). Cancer Gene Ther., 9, 579-586.
59. Kowalski P, Wichert A, Holm PS, Dietel M and Lage H. (2001). Cancer Gene Ther., 8, 185-192.
60. Kruijtzer CM, Beijnen JH, Rosing H, ten Bokkel Huinink WW, Schot M, Jewell RC, Paul EM and Schellens JH. (2002). J. Clin. Oncol., 20, 2943-2950.
61. Langmann T, Porsch-Ozcurumez M, Unkelbach U, Klucken J and Schmitz G. (2000). Biochim. Biophys. Acta, 1494, 175-180.
62. Laurand A, Laroche-Clary A, Larrue A, Bonnet J and Robert J. (2001). Proc. Am. Assoc. Cancer Res., 42, 647 (abstract 3483).
63. Lechner A, Leech CA, Abraham EJ, Nolan AL and Habener JF. (2002). Biochem. Biophys. Res. Commun., 293, 670-674.
64. Lee JS, Scala S, Matsumoto Y, Dickstein B, Robey R, Zhan Z, Altenberg G and Bates SE. (1997). J. Cell. Biochem., 65, 513-526.
65. Leith CP, Kopecky KJ, Chen IM, Eijdems L, Slovak ML, McConnell TS, Head DR, Weick J, Grever MR, Appelbaum FR and Willman CL. (1999). Blood, 94, 1086-1099.
66. List AF, Kopecky KJ, Willman CL, Spier C, Dorr R, Appelbaum F and Hynes H. (1999). Blood, 92, 312a.
67. Litman T, Brangi M, Hudson E, Fetsch P, Abati A, Ross DD, Miyake K, Resau JH and Bates SE. (2000). J. Cell. Sci., 113, 2011-2021.
68. Litman T, Druley TE, Stein WD and Bates SE. (2001). Cell Mol. Life Sci., 58, 931-959.
69. Litman T, Jensen U, Hansen A, Covitz K, Zhan Z, Fetsch P, Abati A, Hansen P, Horn T, Skovsgaard T and Bates S. (2002). Biochim. Biophys. Acta, 1565, 6-16.
70. Maliepaard M, Scheffer GL, Faneyte IF, van Gastelen MA, Pijnenborg AC, Schinkel AH, van De Vijver MJ, Scheper RJ and Schellens JH. (2001a). Cancer Res., 61, 3458-3464.
71. Maliepaard M, van Gastalen MA, de Jong LA, Pluim D, van Waardenburg RCAM, Ruevekamp-Helmers MC and Schellens JHM. (2000). Proc. Am. Assoc. Cancer Res., 41, 268 (abstract 1705).
72. Maliepaard M, van Gastelen MA, de Jong LA, Pluim D, van Waardenburg RC, Ruevekamp-Helmers MC, Floot BG and Schellens JH. (1999). Cancer Res., 59, 4559-4563.
73. Maliepaard M, van Gastelen MA, Tohgo A, Hausheer FH, van Waardenburg RC, de Jong LA, Pluim D, Beijnen JH and Schellens JH. (2001b). Clin. Cancer Res., 7, 935-941.
74. Minderman H, Suvannasankha A, O'Loughlin KL, Allen J, Schinkel A, Scheper RJ, Scheffer GL, Robey RW, Bates SE and Baer MR. (2002a). Proc. Am. Assoc. Cancer Res., 43, 493 (abstract 2465).
75. Minderman H, Suvannasankha A, O'Loughlin KL, Scheffer GL, Scheper RJ, Robey RW and Baer MR. (2002b). Cytometry, 48, 59-65.
76. Miyake K, Mickley L, Litman T, Zhan Z, Robey R, Cristensen B, Brangi M, Greenberger L, Dean M, Fojo T and Bates SE. (1999). Cancer Res., 59, 8-13.
77. Nakagawa M, Schneider E, Dixon KH, Horton J, Kelley K, Morrow C and Cowan KH. (1992). Cancer Res., 52, 6175-6181.
78. Nakanishi T, Karp JE, Tan M, Doyle LA, Peters T, Yang W, Wei D and Ross DD. (2003). Clin. Cancer Res., 9, 3320-3328.
79. Nakatomi K, Yoshikawa M, Oka M, Ikegami Y, Hayasaka S, Sano K, Shiozawa K, Kawabata S, Soda H, Ishikawa T, Tanabe S and Kohno S. (2001). Biochem. Biophys. Res. Commun., 288, 827-832.
80. Ozvegy C, Litman T, Szakacs G, Nagy Z, Bates S, Varadi A and Sarkadi B. (2001). Biochem. Biophys. Res. Commun., 285, 111-117.
81. Ozvegy C, Varadi A and Sarkadi B. (2002). J. Biol. Chem., 8, 8.
82. Perego P, De Cesare M, De Isabella P, Carenini N, Beggiolin G, Pezzoni G, Palumbo M, Tartaglia L, Pratesi G, Pisano C, Carminati P, Scheffer GL and Zunino F. (2001). Cancer Res., 61, 6034-6037.
83. Rabindran SK, He H, Singh M, Brown E, Collins KI, Annable T and Greenberger LM. (1998). Cancer Res., 58, 5850-5858.
84. Rabindran SK, Ross DD, Doyle LA, Yang W and Greenberger LM. (2000). Cancer Res., 60, 47-50.
85. Rajendra R, Gounder MK, Ahamed S, Schellens JHM, Ross DD, Sinko P and Rubin EH. (2002). Proc. Am. Assoc. Cancer Res., 43, 777 (abstract 3853).
86. Robey RW, Honjo Y, van de Laar A, Miyake K, Regis JT, Litman T and Bates SE. (2001a). Biochim. Biophys. Acta, 1512, 171-182.
87. Robey RW, Medina-Perez WY, Nishiyama K, Lahusen T, Miyake K, Litman T, Senderowicz AM, Ross DD and Bates SE. (2001b). Clin. Cancer Res., 7, 145-152.
88. Rocchi E, Khodjakov A, Volk EL, Yang CH, Litman T, Bates SE and Schneider E. (2000). Biochem. Biophys. Res. Commun., 271, 42-46.
89. Ross DD. (2000). Leukemia, 14, 467-473.
90. Ross DD, Doyle LA, Yang W, Tong Y and Cornblatt B. (1995). Biochem. Pharmacol., 50, 1673-1683.
91. Ross DD, Karp JE, Chen TT and Doyle LA. (2000). Blood, 96, 365-368.
92. Ross DD, Yang W, Abruzzo LV, Dalton WS, Schneider E, Lage H, Dietel M, Greenberger L, Cole SP and Doyle LA. (1999). J. Natl. Cancer Inst., 91, 429-433.
93. Sargent JM, Williamson CJ, Maliepaard M, Elgie AW, Scheper RJ and Taylor CG. (2001). Br. J. Haematol., 115, 257-262.
94. Sauerbrey A, Sell W, Steinbach D, Voigt A and Zintl F. (2002). Br. J. Haematol., 118, 147-150.
95. Scharenberg CW, Harkey MA and Torok-Storb B. (2002). Blood, 99, 507-512.
96. Scheffer GL, Maliepaard M, Pijnenborg AC, van Gastelen MA, de Jong MC, Schroeijers AB, van der Kolk DM, Allen JD, Ross DD, van der Valk P, Dalton WS, Scheffer GL, Pijnenborg AC, Smit EF, Muller M, Postma DS, Timens W, van der Valk P, de Vries EG and Scheper RJ. (2000). Cancer Res., 55, 332-339.
97. Scheffer GL, Pijnenborg AC, Smit EF, Muller M, Postma DS, Timens W, van der Valk P, de Vries EG and Scheper RJ. (2002). J. Clin. Pathol., 60, 2589-2593.
98. Schellens JHM, Van Eijndhoven M, van Waardenburg RC, de Jong E, Schinkel AH and Beijnen JH. (2002). Proc. Am. Assoc. Cancer Res., 43, 1154 (abstract 5723).
99. Schlegel S, Klimecki W and List AF. (1999). Proc. Am. Assoc. Cancer Res., 40, 669 (abstract 4415).
100. Schuetz JD, Leggas M, Sampath J, Wall A, Lan L, Cheshire PJ, Peterson J, Stewart CF and Houghton PJ. (2002). Proc. Am. Assoc. Cancer Res., 43, 272 (abstract 1351).
101. Senderowicz AM. (1999). Invest. New Drugs, 17, 313-320.
102. Stein U, Lage H, Jordan A, Walther W, Bates SE, Litman T, Hohenberger P and Dietel M. (2002). Int. J. Cancer, 97, 751-760.
103. Steinbach D, Sell W, Voigt A, Hermann J, Zintl F and Sauerbrey A. (2002). Leukemia, 16, 1443-1447.
104. Sugimoto Y, Tsukahara S, Imai Y, Ueda K and Tsuruo T. (2003). Mol. Cancer Ther., 2, 105-112.
105. Taipalensuu J, Tornblom H, Lindberg G, Einarsson C, Sjoqvist F, Melhus H, Garberg P, Sjostrom B, Lundgren B and Artursson P. (2001). J. Pharmacol. Exp. Ther., 299, 164-170.
106. Takebayashi Y, Nakayama K, Fujioka T, Kanzaki A, Mutho M, Uchida T, Miyazaki K, Ito M and Fukumoto M. (2001). Int. J. Mol. Med., 7, 397-400.
107. Tamaki T, Akatsuka A, Ando K, Nakamura Y, Matsuzawa H, Hotta T, Roy RR and Edgerton VR. (2002). J. Cell Biol., 157, 571-577.
108. Taylor CW, Dalton WS, Parrish PR, Gleason MC, Bellamy WT, Thompson FH, Roe DJ and Trent JM. (1991). Br. J. Cancer, 63, 923-929.
109. Thompson JD, Gibson TJ, Plewniak F, Jeanmougin F and Higgins DG. (1997). Nucleic Acids Res., 25, 4876-4882.
110. Uchida N, Leung FY and Eaves CJ. (2002). Exp. Hematol., 30, 862-869.
111. Ueda K, Pastan I and Gottesman MM. (1987). J. Biol. Chem., 262, 17432-17436.
112. van den Heuvel-Eibrink MM, Sonneveld P and Pieters R. (2000). Int. J. Clin. Pharmacol. Ther., 38, 94-110.
113. van den Heuvel-Eibrink MM, Wiemer EA, Prins A, Meijerink JP, Vossebeld PJ, van der Holt B, Pieters R and Sonneveld P. (2002). Leukemia, 16, 833-839.
114. van der Kolk DM, de Vries EG, Muller M and Vellenga E. (2002a). Leukemia Lymphoma, 43, 685-701.
115. van der Kolk DM, Vellenga E, Scheffer GL, Muller M, Bates SE, Scheper RJ and de Vries EG. (2002b). Blood, 99, 3763-3770.
116. Van Hattum AH, Schluper HM, Hausheer FH, Pinedo HM and Boven E. (2002). Int. J. Cancer, 100, 22-29.
117. Van Hattum AH, Schluper HMM, Pinedo HM and Boven E. (2001). Proc. Am. Assoc. Cancer Res., 42, 815 (abstract 4372).
118. van Loevezijn A, Allen JD, Schinkel AH and Koomen GJ. (2001). Bioorg. Med. Chem. Lett., 11, 29-32.
119. Volk EL, Farley KM and Schneider E. (2002a). Proc. Am. Assoc. Cancer Res., 43, 780 (abstract 3866).
120. Volk EL, Farley KM, Wu Y, Li F, Robey RW and Schneider E. (2002b). Cancer Res., 62, 5035-5040.
121. Volk EL, Rohde K, Rhee M, McGuire JJ, Doyle LA, Ross DD and Schneider E. (2000). Cancer Res., 60, 3514-3521.
122. Wang X, Furukawa T, Nitanda T, Okamoto M, Sugimoto Y, Akiyama S and Baba M. (2003). Mol. Pharmacol., 63, 65-72.
123. Yang CH, Schneider E, Kuo ML, Volk EL, Rocchi E and Chen YC. (2000). Biochem. Pharmacol., 60, 831-837.
124. Yoshikawa M, Hayasaka S, Ikegami Y, Satake K, Ito A, Sano K, Suzuki T, Togawa T, Ishii K, Yoshida H, Oka M, Yabuuchi H, Sawada S, Tanabe S and Ishikawa T. (2002). Proc. Am. Assoc. Cancer Res., 43, 777 (abstract 3852).
125. Young AM, Allen CE and Audus KL. (2003). Adv. Drug Deliv. Rev., 55, 125-132.
126. Zamber CP, Lamba JK, Yasuda K, Farnum J, Thummel K, Schuetz JD and Schuetz EG. (2003). Pharmacogenetics, 13, 19-28.
127. Zhou S, Morris JJ, Barnes Y, Lan L, Schuetz JD and Sorrentino BP. (2002). Proc. Natl. Acad. Sci. USA. 99, 12339-12344.
128. Zhou S, Morris JJ, Bunting KD, Osawa M, Schuetz JD, Nakauchi H and Sorrentino BP. (2000). Blood (Suppl.), 96, 820a (abstract 3545).
129. Zhou S, Schuetz JD, Bunting KD, Colapietro AM, Sampath J, Morris JJ, Lagutina I, Grosveld GC, Osawa M, Nakauchi H and Sorrentino BP. (2001). Nat. Med., 7, 1028-1034.
130. Zhu Q and Center MS. (1994). Cancer Res., 54, 4488-4492.