Human glutathione S-transferase P1 polymorphisms: Relationship to lung tissue enzyme activity and population frequency distribution

Carcinogenesis

Volumn 19, Issue 2, 1998, Pages 275-280

  Watson, Mary A ^a   Stewart, Richard K ^b   Smith, Graeme B J ^b   Massey, Thomas E ^b   Bell, Douglas A ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^b QUEEN S UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

1 CHLORO 2,4 DINITROBENZENE; ALANINE; GLUTATHIONE TRANSFERASE; ISOLEUCINE; LUNG ENZYME; VALINE;

ARTICLE; CANCER SUSCEPTIBILITY; CODON; CONJUGATION; CYTOSOL; ENZYME ACTIVITY; ETHNIC DIFFERENCE; EXON; GENETIC POLYMORPHISM; GENOTYPE; HAPLOTYPE; HUMAN; HUMAN TISSUE; NORMAL HUMAN; POLYMERASE CHAIN REACTION; POPULATION GENETICS; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SMOKING;

AFRICAN CONTINENTAL ANCESTRY GROUP; ASIAN CONTINENTAL ANCESTRY GROUP; CONTINENTAL POPULATION GROUPS; EUROPEAN CONTINENTAL ANCESTRY GROUP; GENE FREQUENCY; GENOTYPE; GLUTATHIONE TRANSFERASE; HUMANS; LUNG; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; TAIWAN; UNITED STATES;

EID: 0031878594     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/19.2.275     Document Type: Article

References (44)

1. Boyer, T.D. and Kenney, W.C. (1985) Preparation, characterization and properties of glutathione S-transferases. In Zakim, D. and Vessey, D. (eds) Biochemical Pharmacology and Toxicology. John Wiley and Sons, New York, NY, pp. 297-363.
2. Mannervik, B. (1985) The isozymes of glutathione S-transferase. Adv. Enzymol., 57, 357-417.
3. Dekant, W. and Vamkars, S. (1993) Glutathione-dependent bioactivation of xenobiotics. Xenobiotica, 23, 873-887.
4. Mannervik, B., Alin, P., Guthenberg, C., Jensson, H., Tahir, M.K., Warholm, M. and Jornvall, H. (1985) Identification of three classes of cytosolic glutathione transferase common to several mammalian species, correlation between structural data and enzymatic properties. Proc. Natl Acad. Sci. USA, 82, 7202-7206.
5. Tsuchida, S. and Sato, K. (1992) Glutathione transferases and cancer. Crit. Rev. Biochem. Mol. Biol., 27, 337-384.
6. Seidgard, J., Vorachek, W.R., Pero, R.W. and Pearson, W.R. (1988) Hereditary differences in the expression of the human glutathione transferase active on trans-stilbene oxide are due to a gene deletion. Proc. Natl Acad. Sci. USA, 85, 7293-7297.
7. Pemble, S., Schroeder, K.R., Spencer, S.R. Meyer, D.J., Hallier, E., Bolt, H.M. Ketterer, B. and Taylor, J.B. (1994). Human glutathione S-transferase theta (GSTT1): cDNA cloning and the characterization of a genetic polymorphism. Biochem. J., 300, 271-276.
8. Wiencke, J.K., Pemble, S., Ketterer, B. and Kelsey, K.T. (1995) Gene deletion of glutathione transferase theta 1: correlation with induced genetic damage and potential role in endogenous mutagenesis. Cancer Epidem. Biomark. Prevent., 4, 253-260.
9. Bell, D.A., Taylor, J.A., Paulson, D.F., Robertson, C.N., Mohler, J.L. and Lucier, G.W. (1993) Genetic risk and carcinogen exposure - a common inherited defect of the carcinogen-metabolism gene glutathione S-transferase M1 (GSTM1) that increases susceptibility to bladder cancer. J. Natl Cancer. Inst., 85, 1159-1164.
10. Seidegard, J., Pero, R.W., Markowitz, M.M., Roush, G., Miller D.G. and Beattie, J. (1990) Isoenzyme(s) of glutathione transferase (class Mu) as a marker for the susceptibility to lung cancer. Carcinogenesis, 11, 33-36.
11. Nazar-Stewart, V., Motulsky, A.G., Eaton, D.L., White, E., Hornung, S.K., Leng, Z.T., Stapleton, P. and Weiss, N.S. (1993) The glutathione S-transferase μ polymorphism as a marker for the susceptibility to lung cancer. Cancer Res., 53, 2313-2318.
12. Hirvonen, A., Husgafvel-Pursiainen, K., Anttila, S. and Vainio, H. (1993) The GSTM1 null genotype as a potential risk modifier for squamous cell carcinoma of the lung. Carcinogenesis, 14, 1479-1481.
13. Chen, H.W., Sandler, D.P., Taylor, J.A, Shore D.L., Liu, E., Bloomfield, C.D. and Bell, D.A. (1996) Increased risk for myelodysplastic syndromes in individuals with glutathione-transferase theta 1 (GSTT1) gene defect. Lancet, 347, 295-297.
14. Terrier, P., Townsend, A.J., Coindre, J.M., Triche, T.J. and Cowan, K.H. (1990) An immunohistochemical study of pi class glutathione S-transferase expression in normal human tissue. Am. J. Pathol., 137, 845-853.
15. Moscow, J.A., Fairchild, C.R., Madden, M.J. et al. (1989) Expression of anionic glutathione-S-transferase and P-glycoprotein genes in human tissues and tumors. Cancer Res., 49, 1422-1428.
16. Singh, S.V., Xu, B.H., Tkalcevic, G.T., Gupta, V., Roberts, B. and Ruiz, P. (1994) Glutathione-linked detoxification pathway in normal and malignant human bladder tissue. Cancer Lett., 77, 15-24.
17. Howie, A.F., Forrester, L.M., Glancey, M.J., Schlager, J.J., Powis, G., Beckett, G.J., Hayes, J.D. and Wolf, C.R. (1990) Glutathione S-transferase and glutathione peroxidase expression in normal and tumor human tissues. Carcinogenesis, 11, 451-458.
18. Singh, S.V., Brunnert, S.R., Roberts, B. and Krishan, A. (1990) Differential expression of glutathione S-transferase, glutathione peroxidase and glutathione reductase in normal and malignant human breast tissues. Cancer Lett., 51, 43-48.
19. Mulder, T.J., Manni, J.J., Roelofs, H.J., Peters, W.M. and Wiersma, A. (1995) Glutathione S-transferases and glutathione in human head and neck cancer. Carcinogenesis, 16, 619-624.
20. Mulder, T.J., Verspaget, H.W., Sier, C.M., Roelofs, H.J., Ganesh, S., Griffioen, G. and Peters, W.M. (1995) Glutathione S-transferase π in colorectal tumors is predictive for overall survival. Cancer Res., 55, 2696-2702.
21. Peters, W.M., Boon, C.W., Roelofs, H.J., Wobbes, T., Nagengast, F.M. and Kremers, P.G. (1992) Expression of drug metabolizing enzymes and P-170 glycoprotein in colorectal carcinoma and normal mucosa. Gastroenterology, 103, 448-455.
22. Peters, W.M., Wormskamp, N.M. and Thies, E. (1990) Expression of glutathione S-transferase in normal gastric mucosa and gastric tumors. Carcinogenesis, 11, 1593-1596.
23. Shimizu, K., Toriyama, F., Shang, H. and Yoshida, H. (1995) The expression of placental-type glutathione S-transferase (GST-π) in human cutaneous carcinoma in situ, that is, actinic keratosis and Bowen's disease, compared with normal human skin. Carcinogenesis, 10, 2327-2330.
24. Sato, K. (1989) Glutathione S-transferases as markers of preneoplasia and neoplasia. Adv. Cancer Res., 52, 205-255.
25. Board, P.G., Weber, G.C. and Coggan, M. (1989) Isolation of a cDNA clone and localization of the human glutathione S-transferase 3 genes to chromosome bands 11q13 and 12q13-14. Ann. Hum. Genet., 53, 205-213.
26. Zimniak, P., Nandur, B., Pikula, S., Bandorowics-Pikula, J., Singhal, S., Srivastava, S., Awashthi, S. and Awasthi, Y. (1994) Naturally occurring human glutathione S-transferase GSTP1-1 isoforms with isoleucine and valine in position 105 differ in enzymatic properties. Eur. J. Biochem., 224, 893-899.
27. Ali-Osman, F., Akande, O., Antoun, G., Mao J. and Buolamwin, J. (1997) Molecular cloning, characterization and expression in Escherichia coli of full-length cDNAs of three human glutathione S-transferase Pi gene variants. J. Biol. Chem., 15, 10004-10012.
28. 1 in rabbit lung and liver microsomes. Carcinogenesis, 11, 823-827.
29. Lowry, O.H., Rosebrough, N.J., Farr, A.L. and Randall, R.J. (1951) Protein measurement with the folin phenol reagent. J. Biol. Chem., 193, 265-275.
30. Habig, W.H., Pabst, M.J. and Jakoby, W.B. (1974) Glutathione S-transferases. The first enzymatic step in mercapturic acid formation. J. Biol. Chem., 249, 7130-7139.
31. Devereux, T.R., Belinsky, S.A., Maronpot, R.R., White, C.M., Hegi, M.E., Patel, A.C., Foley, J.F., Greenwell, A. and Anderson, M.W. (1993) Comparison of pulmonary O-6 methylguanine DNA adduct levels and Ki ras activation in lung-tumors from resistant and susceptible mouse strains. Mol. Carcinogenesis, 8, 177-185.
32. Bartsch H., Bartsch, H., Petruzzelli, S. et al. (1991) Carcinogen metabolism and DNA adducts in human lung tissues as affected by tobacco smoking or metabolic phenotype: A case-control study on lung cancer patients. Mutat. Res., 250, 103-114.
33. McLemore, T.L., Adelberg, S., Liu, M.C., McMahon, N.A., Yu, S.J. and Hubbard, W.C. (1990) Expression of CYP1A1 gene in patients with lung cancer: Evidence for cigarette smoke-induced gene expression in normal lung tissue and for altered gene regulation in primary pulmonary carcinomas. J. Natl Cancer Inst., 82, 1333-1339.
34. 1-DNA adducts in human placenta and cord blood. Cancer Res., 53, 1278-1280.
35. Bell, D.A., Taylor, J.A., Butler, M.A., Stephens, E., Wiest, J., Brubaker, L., Kadlubar, F. and Lucier, G.W. (1993) Genotype/phenotype discordance for human arylamine N-acetyl transferase (NAT2) reveals a new slow-acetylator allele common in African-Americans. Carcinogenesis, 14, 1689-1692.
36. Stephens, E.A., Taylor, J.A., Kaplan, N., Yang, C.-H., Hsieh, L.L., Lucier, G.W. and Bell, D.A. (1994) Ethnic variation in the CYP2E1 gene: Polymorphism analysis of 695 African-Americans, European-Americans and Taiwanese. Pharmacogenetics, 4, 185-192.
37. Harries, L.W., Stubbins M.J., Forman D., Howard G. and Wolf, C.R. (1997) Identification of genetic polymorphisms at the glutathione S-transferase Pi locus and association with susceptibility to bladder, testicular and prostate cancer. Carcinogenesis, 18, 641-644.
38. Singhal, S.S. Saxena, J., Ahmad, H., Awasthi, S., Haque, A.K. and Awasthi, Y.C. (1992) Glutathione S-transferases of human lung: Characterization and evaluation of the protective role of the alpha class isozymes against lipid peroxidation. Arch. Biochem. Biophys., 299, 232-241.
39. Mannervik, B., Awasthi, Y.C., Board, P.G. et al. (1992) Nomenclature for human glutathione transferases. Biochem. J., 282, 305-308.
40. Petruzzelli, S., Camus, A.M., Carrozi, L. et al. (1988) Long lasting effects of tobacco smoking on pulmonary drug-metabolizing enzymes: a case control study on lung cancer patients. Cancer Res., 48, 4695-4700.
41. Nakajima, T., Elovaara, E., Anttilla, S., Hirvonen, A., Camus, A., Hayes, J., Ketterer, B. and Vainio, H. (1995) Expression and polymorphism of glutathione S-transferase in human lungs: risk factors in smoking related lung cancer. Carcinogenesis, 16, 707-711.
42. Cole, S.P., Downes, H.F., Mirski, S.E. and Clements, D.J. (1990) Alterations in glutathione and glutathione related enzymes in a multidrug resistant small cell lung cancer cell line. Mol. Pharmacol., 37, 192-197.
43. Bai, F., Nakanishi, Y., Kawasaki, M., Takayama, K., Yataunami, J., Pei, X.H., Tsuruta, N., Wakamatsu, K. and Hara, N. (1996) Immunohistochemical expression of glutathione S-transferase Pi can predict chemotherapy response in patients with non-small cell lung carcinoma. Cancer, 78, 416-421.
44. Ryberg, D., Skaug, V., Hewer, A. et al. (1997) Genotypes of glutathione transferase M1 and P1 and their significance for lung DNA adduct levels and cancer risk. Carcinogenesis, 18, 1285-1289.