메뉴 건너뛰기




Volumn 22, Issue 9, 2004, Pages 1572-1582

Prognostic value of proliferation, apoptosis, defective DNA mismatch repair, and p53 overexpression in patients with resected Dukes' B2 or C colon cancer: A North Central Cancer Treatment Group study

Author keywords

[No Author keywords available]

Indexed keywords

DNA NUCLEOTIDYLEXOTRANSFERASE; FLUOROURACIL; KI 67 ANTIGEN; PROTEIN BCL 2; PROTEIN P53; TUMOR MARKER;

EID: 2442659386     PISSN: 0732183X     EISSN: None     Source Type: Journal    
DOI: 10.1200/JCO.2004.10.042     Document Type: Article
Times cited : (129)

References (70)
  • 1
    • 0029560117 scopus 로고
    • Adjuvant therapy of colon cancer
    • Shulman K, Schilsky RL: Adjuvant therapy of colon cancer. Semin Oncol 22:600-610, 1995
    • (1995) Semin Oncol , vol.22 , pp. 600-610
    • Shulman, K.1    Schilsky, R.L.2
  • 2
    • 0028376462 scopus 로고
    • Relationship of nuclear DNA content to clinicopathologic features in colorectal cancer
    • Lanza G, Maestri I, Ballotta MR, et al: Relationship of nuclear DNA content to clinicopathologic features in colorectal cancer. Mod Pathol 7:161-165, 1994
    • (1994) Mod Pathol , vol.7 , pp. 161-165
    • Lanza, G.1    Maestri, I.2    Ballotta, M.R.3
  • 4
    • 0035912144 scopus 로고    scopus 로고
    • Molecular predictors of survival after adjuvant chemotherapy for colon cancer
    • Watanabe T, Wu T-T, Catalano PJ, et al: Molecular predictors of survival after adjuvant chemotherapy for colon cancer. N Engl J Med 344:1196-1206, 2001
    • (2001) N Engl J Med , vol.344 , pp. 1196-1206
    • Watanabe, T.1    Wu, T.-T.2    Catalano, P.J.3
  • 5
    • 0345580321 scopus 로고    scopus 로고
    • Assessment of biomarkers in paired primary and recurrent colorectal adenocarcinomas
    • Seong J, Chung EJ, Kim H, et al: Assessment of biomarkers in paired primary and recurrent colorectal adenocarcinomas. Int J Radiat Oncol Biol Phys 45:1167-1173, 1999
    • (1999) Int J Radiat Oncol Biol Phys , vol.45 , pp. 1167-1173
    • Seong, J.1    Chung, E.J.2    Kim, H.3
  • 6
    • 0028941441 scopus 로고
    • Inhibition of apoptosis during development of colorectal cancer
    • Bedi A, Pasricha PJ, Akhtar AJ, et al: Inhibition of apoptosis during development of colorectal cancer. Cancer Res 55:1811-1816, 1995
    • (1995) Cancer Res , vol.55 , pp. 1811-1816
    • Bedi, A.1    Pasricha, P.J.2    Akhtar, A.J.3
  • 7
    • 0029922310 scopus 로고    scopus 로고
    • Apoptosis of colon cancer: Comparison with Ki-67 proliferative activity and expression of p53
    • Takano Y, Saegusa M, Ikenaga M, et al: Apoptosis of colon cancer: Comparison with Ki-67 proliferative activity and expression of p53. J Cancer Res Clin Oncol 122:166-170, 1996
    • (1996) J Cancer Res Clin Oncol , vol.122 , pp. 166-170
    • Takano, Y.1    Saegusa, M.2    Ikenaga, M.3
  • 8
    • 0030950349 scopus 로고    scopus 로고
    • Growth inhibition and apoptotic cell death in uterine cervical carcinoma cells induced by 5-fluorouracil
    • Ueda M, Kumagai K, Ueki K, et al: Growth inhibition and apoptotic cell death in uterine cervical carcinoma cells induced by 5-fluorouracil. Int J Cancer 71:668-674, 1997
    • (1997) Int J Cancer , vol.71 , pp. 668-674
    • Ueda, M.1    Kumagai, K.2    Ueki, K.3
  • 9
    • 0032781795 scopus 로고    scopus 로고
    • Apoptotic and mitotic indices predict survival rates in lymph node-negative colon carcinomas
    • Sinicrope FA, Hart J, Hsu H-A, et al: Apoptotic and mitotic indices predict survival rates in lymph node-negative colon carcinomas. Clin Cancer Res 5:1793-1804, 1999
    • (1999) Clin Cancer Res , vol.5 , pp. 1793-1804
    • Sinicrope, F.A.1    Hart, J.2    Hsu, H.-A.3
  • 10
    • 0029925825 scopus 로고    scopus 로고
    • Apoptotic cell death and its relationship to carcinogenesis in colorectal carcinoma
    • Tsujitani S, Shirai H, Tatebe S, et al: Apoptotic cell death and its relationship to carcinogenesis in colorectal carcinoma. Cancer 77:1711-1716, 1996
    • (1996) Cancer , vol.77 , pp. 1711-1716
    • Tsujitani, S.1    Shirai, H.2    Tatebe, S.3
  • 11
    • 0029868847 scopus 로고    scopus 로고
    • Expression of bcl-2 protein in hyperplastic polyps, adenomas, and carcinomas of the colon
    • Flohil CC, Janssen PA, Bosman FT: Expression of bcl-2 protein in hyperplastic polyps, adenomas, and carcinomas of the colon. J Pathol 178:393-397, 1996
    • (1996) J Pathol , vol.178 , pp. 393-397
    • Flohil, C.C.1    Janssen, P.A.2    Bosman, F.T.3
  • 12
    • 0030458010 scopus 로고    scopus 로고
    • Increased apoptosis accompanies neoplastic development in the human colorectum
    • Sinicrope FA, Roddey G, McDonnell TJ, et al: Increased apoptosis accompanies neoplastic development in the human colorectum. Clin Cancer Res 2:1999-2006, 1996
    • (1996) Clin Cancer Res , vol.2 , pp. 1999-2006
    • Sinicrope, F.A.1    Roddey, G.2    McDonnell, T.J.3
  • 13
    • 0034126738 scopus 로고    scopus 로고
    • The incidence of apoptosis during colorectal tumorigenesis
    • Sugao Y, Koji T, Yao T, et al: The incidence of apoptosis during colorectal tumorigenesis. Int J Surg Pathol 8:123-132, 2000
    • (2000) Int J Surg Pathol , vol.8 , pp. 123-132
    • Sugao, Y.1    Koji, T.2    Yao, T.3
  • 14
    • 0032928815 scopus 로고    scopus 로고
    • The role of bcl-2 in the progression of the colorectal adenoma-carcinoma sequence
    • Yang H-B, Chow N-H, Sheu B-S, et al: The role of bcl-2 in the progression of the colorectal adenoma-carcinoma sequence. Anticancer Res 19:727-730, 1999
    • (1999) Anticancer Res , vol.19 , pp. 727-730
    • Yang, H.-B.1    Chow, N.-H.2    Sheu, B.-S.3
  • 15
    • 0030746171 scopus 로고    scopus 로고
    • Expression of bcl-2 and p53 in the colorectal adenoma-carcinoma sequence
    • Hao XP, Ilyas M, Talbot IC: Expression of bcl-2 and p53 in the colorectal adenoma-carcinoma sequence. Pathobiology 65:140-145, 1997
    • (1997) Pathobiology , vol.65 , pp. 140-145
    • Hao, X.P.1    Ilyas, M.2    Talbot, I.C.3
  • 16
    • 0028335717 scopus 로고
    • Tumor suppressor p53 is a regulator of bcl-2 and bax gene expression in vitro and in vivo
    • Miyashita T, Krajewski S, Krajewska M, et al: Tumor suppressor p53 is a regulator of bcl-2 and bax gene expression in vitro and in vivo. Oncogene 9:1799-1805, 1994
    • (1994) Oncogene , vol.9 , pp. 1799-1805
    • Miyashita, T.1    Krajewski, S.2    Krajewska, M.3
  • 17
    • 0028068167 scopus 로고
    • Paradoxical inhibition of solid tumor cell growth by bcl-2
    • Pietenpol JA, Papadopoulos N, Markowitz S, et al: Paradoxical inhibition of solid tumor cell growth by bcl-2. Cancer Res 54:3714-3717, 1994
    • (1994) Cancer Res , vol.54 , pp. 3714-3717
    • Pietenpol, J.A.1    Papadopoulos, N.2    Markowitz, S.3
  • 18
    • 0029937032 scopus 로고    scopus 로고
    • Early expression of bcl-2 protein in the adenoma-carcinoma sequence of colorectal neoplasia
    • Kaklamanis L, Savage A, Mortensen N, et al: Early expression of bcl-2 protein in the adenoma-carcinoma sequence of colorectal neoplasia. J Pathol 179:10-14, 1996
    • (1996) J Pathol , vol.179 , pp. 10-14
    • Kaklamanis, L.1    Savage, A.2    Mortensen, N.3
  • 19
    • 0031802007 scopus 로고    scopus 로고
    • Bcl-2 protein expression: Association with p53 and prognosis in colorectal cancer
    • Kaklamanis L, Savage A, Whitehouse R, et al: Bcl-2 protein expression: Association with p53 and prognosis in colorectal cancer. Br J Cancer 77:1864-1869, 1998
    • (1998) Br J Cancer , vol.77 , pp. 1864-1869
    • Kaklamanis, L.1    Savage, A.2    Whitehouse, R.3
  • 20
    • 0034025130 scopus 로고    scopus 로고
    • Protein expression of p53, p21 (waf1/cip1), bcl-2, bax, cyclin D1 and pRb in human colon carcinomas
    • Bukholm IK, Nesland JM: Protein expression of p53, p21 (waf1/cip1), bcl-2, bax, cyclin D1 and pRb in human colon carcinomas. Virchows Arch 436:224-228, 2000
    • (2000) Virchows Arch , vol.436 , pp. 224-228
    • Bukholm, I.K.1    Nesland, J.M.2
  • 21
    • 0032764011 scopus 로고    scopus 로고
    • Evaluation of multiple bio-pathological factors in colorectal adenocarcinomas: Independent prognostic role of p53 and bcl-2
    • Buglioni S, D'Agnano I, Cosimelli M, et al: Evaluation of multiple bio-pathological factors in colorectal adenocarcinomas: Independent prognostic role of p53 and bcl-2. Int J Cancer 84:545-552, 1999
    • (1999) Int J Cancer , vol.84 , pp. 545-552
    • Buglioni, S.1    D'Agnano, I.2    Cosimelli, M.3
  • 22
    • 0032870022 scopus 로고    scopus 로고
    • Genetic and epigenetic contributions to colorectal cancer
    • Dumont N: Genetic and epigenetic contributions to colorectal cancer. APMIS 107:711-722, 1999
    • (1999) APMIS , vol.107 , pp. 711-722
    • Dumont, N.1
  • 23
    • 0032514366 scopus 로고    scopus 로고
    • Chromosome number and structure both are markedly stable in RER colorectal cancers and are not destabilized by mutation of p53
    • Eshleman JR, Casey G, Kochera ME, et al: Chromosome number and structure both are markedly stable in RER colorectal cancers and are not destabilized by mutation of p53. Oncogene 17:719-725, 1998
    • (1998) Oncogene , vol.17 , pp. 719-725
    • Eshleman, J.R.1    Casey, G.2    Kochera, M.E.3
  • 24
    • 0033669763 scopus 로고    scopus 로고
    • Specific patterns of chromosomal abnormalities are associated with RER status in sporadic colorectal cancer
    • Curtis LJ, Georgiades IB, White S, et al: Specific patterns of chromosomal abnormalities are associated with RER status in sporadic colorectal cancer. J Pathol 192:440-445, 2000
    • (2000) J Pathol , vol.192 , pp. 440-445
    • Curtis, L.J.1    Georgiades, I.B.2    White, S.3
  • 25
    • 0037083484 scopus 로고    scopus 로고
    • Immunohistochemistry versus microsatellite instability testing in phenotyping colorectal tumors
    • Lindor NM, Burgart LJ, Leontovich O, et al: Immunohistochemistry versus microsatellite instability testing in phenotyping colorectal tumors. J Clin Oncol 20:1043-1048, 2002
    • (2002) J Clin Oncol , vol.20 , pp. 1043-1048
    • Lindor, N.M.1    Burgart, L.J.2    Leontovich, O.3
  • 26
    • 0038002279 scopus 로고    scopus 로고
    • Tumor microsatellite status as a predictor of benefit from fluorouracil-based adjuvant chemotherapy for colon cancer
    • Ribic CM, Sargent DJ, Moore MJ, et al: Tumor microsatellite status as a predictor of benefit from fluorouracil-based adjuvant chemotherapy for colon cancer. N Engl J Med 349:247-257, 2003
    • (2003) N Engl J Med , vol.349 , pp. 247-257
    • Ribic, C.M.1    Sargent, D.J.2    Moore, M.J.3
  • 27
    • 0034997971 scopus 로고    scopus 로고
    • Microsatellite instability and the clinicopathological features of sporadic colorectal cancer
    • Ward R, Meagher A, Tomlinson I, et al: Microsatellite instability and the clinicopathological features of sporadic colorectal cancer. Gut 48:821-829, 2001
    • (2001) Gut , vol.48 , pp. 821-829
    • Ward, R.1    Meagher, A.2    Tomlinson, I.3
  • 28
    • 0028985062 scopus 로고
    • Mutation of the p53 gene precedes aneuploid clonal divergence in colorectal carcinoma
    • Carder PJ, Cripps KJ, Morris R, et al: Mutation of the p53 gene precedes aneuploid clonal divergence in colorectal carcinoma. Br J Cancer 71:215-218, 1995
    • (1995) Br J Cancer , vol.71 , pp. 215-218
    • Carder, P.J.1    Cripps, K.J.2    Morris, R.3
  • 29
    • 0027155978 scopus 로고
    • Stabilised p53 facilitates aneuploid clonal divergence in colorectal carcinoma
    • Carder PJ, Wyllie AH, Purdie CA, et al: Stabilised p53 facilitates aneuploid clonal divergence in colorectal carcinoma. Oncogene 8:1397-1401, 1993
    • (1993) Oncogene , vol.8 , pp. 1397-1401
    • Carder, P.J.1    Wyllie, A.H.2    Purdie, C.A.3
  • 30
    • 0025060806 scopus 로고
    • Levamisole and fluorouracil for adjuvant therapy of resected colon carcinoma
    • Moertel CG, Fleming TR, Macdonald JS, et al: Levamisole and fluorouracil for adjuvant therapy of resected colon carcinoma. N Engl J Med 322:352-358, 1990
    • (1990) N Engl J Med , vol.322 , pp. 352-358
    • Moertel, C.G.1    Fleming, T.R.2    Macdonald, J.S.3
  • 31
    • 0028136295 scopus 로고
    • Improving adjuvant therapy for rectal cancer by combining protracted-infusion fluorouracil with radiation therapy after curative surgery
    • O'Connell MJ, Martenson JA, Wieand HS, et al: Improving adjuvant therapy for rectal cancer by combining protracted-infusion fluorouracil with radiation therapy after curative surgery. N Engl J Med 331:502-507, 1994
    • (1994) N Engl J Med , vol.331 , pp. 502-507
    • O'Connell, M.J.1    Martenson, J.A.2    Wieand, H.S.3
  • 32
    • 0029129603 scopus 로고
    • Controlled clinical trial of interferon-gamma as postoperative surgical adjuvant therapy for colon cancer
    • Wiesenfeld M, O'Connell MJ, Wieand HS, et al: Controlled clinical trial of interferon-gamma as postoperative surgical adjuvant therapy for colon cancer. J Clin Oncol 13:2324-2329, 1995
    • (1995) J Clin Oncol , vol.13 , pp. 2324-2329
    • Wiesenfeld, M.1    O'Connell, M.J.2    Wieand, H.S.3
  • 33
    • 0031022988 scopus 로고    scopus 로고
    • Controlled trial of fluorouracil and low-dose leucovorin given for 6 months as postoperative adjuvant therapy for colon cancer
    • O'Connell MJ, Mailliard JA, Kahn MJ, et al: Controlled trial of fluorouracil and low-dose leucovorin given for 6 months as postoperative adjuvant therapy for colon cancer. J Clin Oncol 15:246-250, 1997
    • (1997) J Clin Oncol , vol.15 , pp. 246-250
    • O'Connell, M.J.1    Mailliard, J.A.2    Kahn, M.J.3
  • 34
    • 0037391604 scopus 로고    scopus 로고
    • Identifying and quantifying apoptosis: Navigating technical pitfalls
    • Garrity MM, Burgart LJ, Riehle DL, et al: Identifying and quantifying apoptosis: Navigating technical pitfalls. Mod Pathol 16:389-394, 2003
    • (2003) Mod Pathol , vol.16 , pp. 389-394
    • Garrity, M.M.1    Burgart, L.J.2    Riehle, D.L.3
  • 35
    • 0032742243 scopus 로고    scopus 로고
    • Cell proliferation in prostate cancer patients with lymph node metastasis: A marker for progression
    • Cheng L, Pisansky TM, Sebo TJ, et al: Cell proliferation in prostate cancer patients with lymph node metastasis: A marker for progression. Clin Cancer Res 5:2820-2823, 1999
    • (1999) Clin Cancer Res , vol.5 , pp. 2820-2823
    • Cheng, L.1    Pisansky, T.M.2    Sebo, T.J.3
  • 36
    • 0026045053 scopus 로고
    • DNA ploidy and cell kinetic measurements as predictors of recurrence and survival in stages B2 and C colorectal cancer
    • Witzig TE, Loprinzi DC, Gonchoroff NJ, et al: DNA ploidy and cell kinetic measurements as predictors of recurrence and survival in stages B2 and C colorectal cancer. Cancer 68:879-888, 1991
    • (1991) Cancer , vol.68 , pp. 879-888
    • Witzig, T.E.1    Loprinzi, D.C.2    Gonchoroff, N.J.3
  • 37
    • 33845382806 scopus 로고
    • Nonparametric estimation for incomplete observations
    • Kaplan E, Meier P: Nonparametric estimation for incomplete observations. J Am Stat Assoc 53:457-481, 1958
    • (1958) J Am Stat Assoc , vol.53 , pp. 457-481
    • Kaplan, E.1    Meier, P.2
  • 38
    • 0000336139 scopus 로고
    • Regression models and life tables
    • Cox D: Regression models and life tables (with discussion). J R Stat Soc (B) 34:187-220, 1972
    • (1972) J R Stat Soc (B) , vol.34 , pp. 187-220
    • Cox, D.1
  • 39
    • 70449647008 scopus 로고
    • Proportional hazards tests and diagnostics based on weighted residuals
    • Grambash PM, Therneau TM: Proportional hazards tests and diagnostics based on weighted residuals. Biometrika 81:515-526, 1994
    • (1994) Biometrika , vol.81 , pp. 515-526
    • Grambash, P.M.1    Therneau, T.M.2
  • 41
    • 0031947209 scopus 로고    scopus 로고
    • Ki-67 expression as a prognostic marker in patients with hepatocellular carcinoma
    • King K, Hwang J, Chau G, et al: Ki-67 expression as a prognostic marker in patients with hepatocellular carcinoma. J Gastroenterol Hepatol 13:273-279, 1998
    • (1998) J Gastroenterol Hepatol , vol.13 , pp. 273-279
    • King, K.1    Hwang, J.2    Chau, G.3
  • 42
    • 20244374922 scopus 로고    scopus 로고
    • Ki-67 expression in breast carcinoma
    • Trihia H, Murray S, Price K, et al: Ki-67 expression in breast carcinoma. Cancer 97:1321-1331, 2003
    • (2003) Cancer , vol.97 , pp. 1321-1331
    • Trihia, H.1    Murray, S.2    Price, K.3
  • 43
    • 0036875813 scopus 로고    scopus 로고
    • Prognostic significance of p53, bcl-2 and Ki-67 in high risk superficial bladder cancer
    • Stavropoulos NE, Filiadis I, Ioachim E, et al: Prognostic significance of p53, bcl-2 and Ki-67 in high risk superficial bladder cancer. Anticancer Res 22:3759-3764, 2002
    • (2002) Anticancer Res , vol.22 , pp. 3759-3764
    • Stavropoulos, N.E.1    Filiadis, I.2    Ioachim, E.3
  • 44
    • 0036771793 scopus 로고    scopus 로고
    • Elevated (> or =10%) MIB-1 proliferative index correlates with poor outcome in gastric stromal tumor patients: A study of 35 cases
    • Toquet C, Le Neel JC, Guillou L, et al: Elevated (> or =10%) MIB-1 proliferative index correlates with poor outcome in gastric stromal tumor patients: A study of 35 cases. Dig Dis Sci 47:2247-2253, 2002
    • (2002) Dig Dis Sci , vol.47 , pp. 2247-2253
    • Toquet, C.1    Le Neel, J.C.2    Guillou, L.3
  • 45
    • 0035240070 scopus 로고    scopus 로고
    • Low proliferative rate of invasive node-negative breast cancer predicts for a favorable outcome: A prospective evaluation of 669 patients
    • Jones S, Clark G, Koleszar S, et al: Low proliferative rate of invasive node-negative breast cancer predicts for a favorable outcome: A prospective evaluation of 669 patients. Clin Breast Cancer 1:310-314, 2001
    • (2001) Clin Breast Cancer , vol.1 , pp. 310-314
    • Jones, S.1    Clark, G.2    Koleszar, S.3
  • 46
    • 0036338490 scopus 로고    scopus 로고
    • Low proliferation activity may be associated with chemoresistance in clear cell carcinoma of the ovary
    • Itamochi H, Kigawa J, Sugiyama T, et al: Low proliferation activity may be associated with chemoresistance in clear cell carcinoma of the ovary. Obstet Gynecol 100:281-287, 2002
    • (2002) Obstet Gynecol , vol.100 , pp. 281-287
    • Itamochi, H.1    Kigawa, J.2    Sugiyama, T.3
  • 47
    • 0033766876 scopus 로고    scopus 로고
    • Assessment of proliferation index with MIB-1 as a prognostic factor in radiation therapy for cervical cancer
    • Suzuki M, Tsukagoshi S, Saga Y, et al: Assessment of proliferation index with MIB-1 as a prognostic factor in radiation therapy for cervical cancer. Gynecol Oncol 79:300-304, 2000
    • (2000) Gynecol Oncol , vol.79 , pp. 300-304
    • Suzuki, M.1    Tsukagoshi, S.2    Saga, Y.3
  • 48
    • 0033795046 scopus 로고    scopus 로고
    • Is MIB-1 proliferation index a predictor for response to neoadjuvant therapy in patients with esophageal cancer?
    • Imdahl A, Jenkner J, Ihling C, et al: Is MIB-1 proliferation index a predictor for response to neoadjuvant therapy in patients with esophageal cancer? Am J Surg 179:514-520, 2000
    • (2000) Am J Surg , vol.179 , pp. 514-520
    • Imdahl, A.1    Jenkner, J.2    Ihling, C.3
  • 49
    • 0037440051 scopus 로고    scopus 로고
    • Prognostic value of thymidylate synthase, Ki-67, and p53 in patients with Dukes' B and C colon cancer: A national cancer institute-national surgical adjuvant breast and bowel project collaborative study
    • Allegra CJ, Paik S, Colangelo LH, et al: Prognostic value of thymidylate synthase, Ki-67, and p53 in patients with Dukes' B and C colon cancer: A national cancer institute-national surgical adjuvant breast and bowel project collaborative study. J Clin Oncol 21:241-250, 2003
    • (2003) J Clin Oncol , vol.21 , pp. 241-250
    • Allegra, C.J.1    Paik, S.2    Colangelo, L.H.3
  • 50
    • 0037051707 scopus 로고    scopus 로고
    • Insulin-like growth factor-I has a biphasic effect on colon carcinoma cells through transient inactivation of the forkhead1, initially mitogenic, then mediating growth arrest and differentiation
    • Ewton DZ, Kansra S, Lim S, et al: Insulin-like growth factor-I has a biphasic effect on colon carcinoma cells through transient inactivation of the forkhead1, initially mitogenic, then mediating growth arrest and differentiation. Int J Cancer 98:665-673, 2002
    • (2002) Int J Cancer , vol.98 , pp. 665-673
    • Ewton, D.Z.1    Kansra, S.2    Lim, S.3
  • 51
    • 0029894216 scopus 로고    scopus 로고
    • Cell cycle analysis of 932 flow cytometric DNA histograms of fresh frozen breast carcinoma material
    • Bergers E, van Diest PJ, Baak JPA: Cell cycle analysis of 932 flow cytometric DNA histograms of fresh frozen breast carcinoma material. Cancer 77:2258-2266, 1996
    • (1996) Cancer , vol.77 , pp. 2258-2266
    • Bergers, E.1    Van Diest, P.J.2    Baak, J.P.A.3
  • 52
    • 0034123054 scopus 로고    scopus 로고
    • Comparison between different cell kinetic variables in human breast cancer
    • Barzanti F, Dal Susino M, Volpi A, et al: Comparison between different cell kinetic variables in human breast cancer. Cell Prolif 33:75-89, 2000
    • (2000) Cell Prolif , vol.33 , pp. 75-89
    • Barzanti, F.1    Dal Susino, M.2    Volpi, A.3
  • 53
    • 0035200978 scopus 로고    scopus 로고
    • Proliferative activity in invasive breast carcinoma: A comprehensive comparison of MIB-1 immunocytochemical staining in aspiration biopsies to image analytic, flow cytometric and histologic parameters
    • Ostrowski ML, Pindur J, Laucirica R, et al: Proliferative activity in invasive breast carcinoma: A comprehensive comparison of MIB-1 immunocytochemical staining in aspiration biopsies to image analytic, flow cytometric and histologic parameters. Acta Cytol 45:965-972, 2001
    • (2001) Acta Cytol , vol.45 , pp. 965-972
    • Ostrowski, M.L.1    Pindur, J.2    Laucirica, R.3
  • 54
    • 0034489526 scopus 로고    scopus 로고
    • Biological characterisation of superficial bladder cancer by bivariate cytokeratin 7/DNA analysis, flow cytometric assessment of MIB-1, and an immunohistochemical study
    • Leonardi E, Dalla Palma P, Reich A, et al: Biological characterisation of superficial bladder cancer by bivariate cytokeratin 7/DNA analysis, flow cytometric assessment of MIB-1, and an immunohistochemical study. Anal Cell Pathol 21:21-33, 2000
    • (2000) Anal Cell Pathol , vol.21 , pp. 21-33
    • Leonardi, E.1    Dalla Palma, P.2    Reich, A.3
  • 55
    • 0025312728 scopus 로고
    • A genetic model for colorectal tumorigenesis
    • Fearon ER, Vogelstein B: A genetic model for colorectal tumorigenesis. Cell 61:759-767, 1990
    • (1990) Cell , vol.61 , pp. 759-767
    • Fearon, E.R.1    Vogelstein, B.2
  • 56
    • 0033814693 scopus 로고    scopus 로고
    • Colorectal carcinogenesis based on molecular biology of early colorectal cancer, with special reference to nonpolypoid (superficial) lesions
    • Watanabe T, Muto T: Colorectal carcinogenesis based on molecular biology of early colorectal cancer, with special reference to nonpolypoid (superficial) lesions. World J Surg 24: 1091-1097, 2000
    • (2000) World J Surg , vol.24 , pp. 1091-1097
    • Watanabe, T.1    Muto, T.2
  • 57
    • 0028989844 scopus 로고
    • Bcl-2 oncoprotein in colorectal hyperplastic polyps, adenomas, and adenocarcinomas
    • Bosari S, Moneghini L, Graziani D, et al: Bcl-2 oncoprotein in colorectal hyperplastic polyps, adenomas, and adenocarcinomas. Hum Pathol 26:534-540, 1995
    • (1995) Hum Pathol , vol.26 , pp. 534-540
    • Bosari, S.1    Moneghini, L.2    Graziani, D.3
  • 58
    • 0036534002 scopus 로고    scopus 로고
    • Investigation of the prognostic and predictive value of thymidylate synthase, p53, and Ki-67 in patients with locally advanced colon cancer
    • Allegra CJ, Parr AL, Wold LE, et al: Investigation of the prognostic and predictive value of thymidylate synthase, p53, and Ki-67 in patients with locally advanced colon cancer. J Clin Oncol 20:1735-1743, 2002
    • (2002) J Clin Oncol , vol.20 , pp. 1735-1743
    • Allegra, C.J.1    Parr, A.L.2    Wold, L.E.3
  • 59
    • 0030753698 scopus 로고    scopus 로고
    • P53 alterations are associated with improved prognosis in distal colonic carcinomas
    • Soong R, Grieu F, Bobbins P, et al: p53 alterations are associated with improved prognosis in distal colonic carcinomas. Clin Cancer Res 3:1405-1411, 1997
    • (1997) Clin Cancer Res , vol.3 , pp. 1405-1411
    • Soong, R.1    Grieu, F.2    Bobbins, P.3
  • 60
    • 0028978774 scopus 로고
    • P53 gene mutations, p53 protein accumulation and compartmentalization in colorectal adenocarcinoma
    • Bosari S, Viale G, Roncalli M, et al: p53 gene mutations, p53 protein accumulation and compartmentalization in colorectal adenocarcinoma. Am J Pathol 147:790-798, 1995
    • (1995) Am J Pathol , vol.147 , pp. 790-798
    • Bosari, S.1    Viale, G.2    Roncalli, M.3
  • 61
    • 0034812396 scopus 로고    scopus 로고
    • Mechanisms of oncogenesis in colon versus rectal cancer
    • Kapiteijn E, Liefers GJ, Los LC, et al: Mechanisms of oncogenesis in colon versus rectal cancer. J Pathol 195:171-178, 2001
    • (2001) J Pathol , vol.195 , pp. 171-178
    • Kapiteijn, E.1    Liefers, G.J.2    Los, L.C.3
  • 62
    • 0038747299 scopus 로고    scopus 로고
    • Prognostic significance of p53 nuclear and cytoplasmic overexpression in right and left colorectal adenocarcinomas
    • Sun XF, Carstensen JM, Zhang H, et al: Prognostic significance of p53 nuclear and cytoplasmic overexpression in right and left colorectal adenocarcinomas. Eur J Cancer 32A:1963-1967, 1996
    • (1996) Eur J Cancer , vol.32 A , pp. 1963-1967
    • Sun, X.F.1    Carstensen, J.M.2    Zhang, H.3
  • 63
    • 0028286988 scopus 로고
    • Cytoplasmic accumulation of p53 protein: An independent prognostic indictor in colorectal adenocarcinomas
    • Bosari S, Viale G, Bossi P, et al: Cytoplasmic accumulation of p53 protein: An independent prognostic indictor in colorectal adenocarcinomas. J Natl Cancer Inst 86:681-687, 1994
    • (1994) J Natl Cancer Inst , vol.86 , pp. 681-687
    • Bosari, S.1    Viale, G.2    Bossi, P.3
  • 64
    • 0033192444 scopus 로고    scopus 로고
    • P53 point mutation and survival in colorectal cancer patients: Effect of disease dissemination and tumor location
    • Goh H, Elnatan J, Low CH, et al: p53 point mutation and survival in colorectal cancer patients: Effect of disease dissemination and tumor location. Int J Oncol 15:491-498, 1999
    • (1999) Int J Oncol , vol.15 , pp. 491-498
    • Goh, H.1    Elnatan, J.2    Low, C.H.3
  • 65
    • 0031929626 scopus 로고    scopus 로고
    • TP53 and long term prognosis in colorectal cancer Mutations in the L3 zinc-binding domain predict poor survival
    • Borresen-Dale AL, Lothe RA, Meling GI, et al: TP53 and long term prognosis in colorectal cancer Mutations in the L3 zinc-binding domain predict poor survival. Clin Cancer Res 4:203-210, 1998
    • (1998) Clin Cancer Res , vol.4 , pp. 203-210
    • Borresen-Dale, A.L.1    Lothe, R.A.2    Meling, G.I.3
  • 66
    • 0028093479 scopus 로고
    • A study of stabilisation of p53 protein versus point mutation in colorectal carcinoma
    • Cripps KJ, Purdie CA, Carder PJ, et al: A study of stabilisation of p53 protein versus point mutation in colorectal carcinoma. Oncogene 9:2739-2743, 1994
    • (1994) Oncogene , vol.9 , pp. 2739-2743
    • Cripps, K.J.1    Purdie, C.A.2    Carder, P.J.3
  • 67
    • 0030443473 scopus 로고    scopus 로고
    • Prognostic significance of p53 abnormalities in colorectal carcinoma detected by PCR-SSCP and immunohistochemical analysis
    • Leahy DT, Salman R, Mulcahy H, et al: Prognostic significance of p53 abnormalities in colorectal carcinoma detected by PCR-SSCP and immunohistochemical analysis. J Pathol 180: 364-370, 1996
    • (1996) J Pathol , vol.180 , pp. 364-370
    • Leahy, D.T.1    Salman, R.2    Mulcahy, H.3
  • 68
    • 0034026701 scopus 로고    scopus 로고
    • P53 and Ki-ras as prognostic factors for Dukes' stage B colorectal cancer
    • Bouzourene H, Gervaz P, Cerottini JP, et al: p53 and Ki-ras as prognostic factors for Dukes' stage B colorectal cancer. Eur J Cancer 36:1008-1015, 2000
    • (2000) Eur J Cancer , vol.36 , pp. 1008-1015
    • Bouzourene, H.1    Gervaz, P.2    Cerottini, J.P.3
  • 69
    • 0033570235 scopus 로고    scopus 로고
    • Combined role of tumor angiogenesis, bcl-2, and p53 expression in the prognosis of patients with colorectal carcinoma
    • Giatromanolaki A, Stathopoulos GP, Tsiobanou E, et al: Combined role of tumor angiogenesis, bcl-2, and p53 expression in the prognosis of patients with colorectal carcinoma. Cancer 86:1421-1430, 1999
    • (1999) Cancer , vol.86 , pp. 1421-1430
    • Giatromanolaki, A.1    Stathopoulos, G.P.2    Tsiobanou, E.3
  • 70
    • 0028171960 scopus 로고
    • P53 nuclear overexpression: An independent predictor of survival in lymph node-positive colorectal cancer patients
    • Zeng ZS, Sarkis AS, Zhang ZF, et al: p53 nuclear overexpression: An independent predictor of survival in lymph node-positive colorectal cancer patients. J Clin Oncol 12:2043-2050, 1994
    • (1994) J Clin Oncol , vol.12 , pp. 2043-2050
    • Zeng, Z.S.1    Sarkis, A.S.2    Zhang, Z.F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.