메뉴 건너뛰기




Volumn 33, Issue 4, 2003, Pages 970-979

The CD4-related molecule, LAG-3 (CD223), regulates the expansion of activated T cells

Author keywords

Activation; CD223; LAG 3; Mouse; T cell

Indexed keywords

ANTIGEN; CD4 ANTIGEN DERIVATIVE; ENTEROTOXIN; GAMMA INTERFERON; GLUTAMIC ACID; INTERLEUKIN 2; ISOLEUCINE; LEUCINE; LYMPHOCYTE ACTIVATION PROTEIN; LYSINE; RETROVIRUS VECTOR; STAPHYLOCOCCUS TOXIN; UNCLASSIFIED DRUG;

EID: 0038068048     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/eji.200323382     Document Type: Review
Times cited : (250)

References (48)
  • 2
    • 0035102242 scopus 로고    scopus 로고
    • Contrasting roles of IL-2 and IL-15 in the life and death of lymphocytes: Implications for immunotherapy
    • Waldmann, T. A., Dubois, S. and Tagaya, Y., Contrasting roles of IL-2 and IL-15 in the life and death of lymphocytes: implications for immunotherapy. Immunity 2001. 14: 105-110.
    • (2001) Immunity , vol.14 , pp. 105-110
    • Waldmann, T.A.1    Dubois, S.2    Tagaya, Y.3
  • 6
    • 0033018101 scopus 로고    scopus 로고
    • T cell co-stimulatory molecules other than CD28
    • Watts, T. H. and DeBenedette, M. A., T cell co-stimulatory molecules other than CD28. Curr. Opin. Immunol. 1999. 11: 286-293.
    • (1999) Curr. Opin. Immunol. , vol.11 , pp. 286-293
    • Watts, T.H.1    DeBenedette, M.A.2
  • 9
    • 0028867420 scopus 로고
    • Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4
    • Tivol, E. A., Borriello, F., Schweitzer, A. N., Lynch, W. P., Bluestone, J. A. and Sharpe, A. H., Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4. Immunity 1995. 3: 541-547.
    • (1995) Immunity , vol.3 , pp. 541-547
    • Tivol, E.A.1    Borriello, F.2    Schweitzer, A.N.3    Lynch, W.P.4    Bluestone, J.A.5    Sharpe, A.H.6
  • 13
    • 0032532284 scopus 로고    scopus 로고
    • CD3/TCR complex-associated lymphocyte activation gene-3 molecules inhibit CD3/TCR signaling
    • Hannier, S., Tournier, M., Bismuth, G. and Triebel, F., CD3/TCR complex-associated lymphocyte activation gene-3 molecules inhibit CD3/TCR signaling. J. Immunol. 1998. 161: 4058-4065.
    • (1998) J. Immunol. , vol.161 , pp. 4058-4065
    • Hannier, S.1    Tournier, M.2    Bismuth, G.3    Triebel, F.4
  • 14
    • 0031446563 scopus 로고    scopus 로고
    • Genomic organization of the human LAG-3/CD4 locus
    • Bruniquel, D., Borie, N. and Triebel, F., Genomic organization of the human LAG-3/CD4 locus. Immunogenetics 1997. 47: 96-98.
    • (1997) Immunogenetics , vol.47 , pp. 96-98
    • Bruniquel, D.1    Borie, N.2    Triebel, F.3
  • 15
    • 0030271397 scopus 로고    scopus 로고
    • Cloning of murine LAG-3 by magnetic bead-bound homologous probes and PCR (gene-capture PCR)
    • Mastrangeli, R., Micangeli, E. and Donini, S., Cloning of murine LAG-3 by magnetic bead-bound homologous probes and PCR (gene-capture PCR). Anal. Biochem. 1996. 241: 93-102.
    • (1996) Anal. Biochem. , vol.241 , pp. 93-102
    • Mastrangeli, R.1    Micangeli, E.2    Donini, S.3
  • 17
    • 0027979962 scopus 로고
    • Cellular expression and tissue distribution of the human LAG-3-encoded protein, an MHC class II ligand
    • Huard, B., Gaulard, P., Faure, F., Hercend, T. and Triebel, F., Cellular expression and tissue distribution of the human LAG-3-encoded protein, an MHC class II ligand. Immunogenetics 1994. 39: 213-217.
    • (1994) Immunogenetics , vol.39 , pp. 213-217
    • Huard, B.1    Gaulard, P.2    Faure, F.3    Hercend, T.4    Triebel, F.5
  • 18
  • 19
    • 0029129218 scopus 로고
    • CD4/major histocompatibility complex class II interaction analyzed with CD4- and lymphocyte activation gene-3 (LAG-3)-Ig fusion proteins
    • Huard, B., Prigent, P., Tournier, M., Bruniquel, D. and Triebel, F., CD4/major histocompatibility complex class II interaction analyzed with CD4- and lymphocyte activation gene-3 (LAG-3)-Ig fusion proteins. Eur. J. Immunol. 1995. 25: 2718-2721.
    • (1995) Eur. J. Immunol. , vol.25 , pp. 2718-2721
    • Huard, B.1    Prigent, P.2    Tournier, M.3    Bruniquel, D.4    Triebel, F.5
  • 20
    • 0034114926 scopus 로고    scopus 로고
    • A soluble lymphocyte activation gene-3 molecule used as a vaccine adjuvant elicits greater humoral and cellular immune responses to both particulate and soluble antigens
    • El Mir, S. and Triebel, F., A soluble lymphocyte activation gene-3 molecule used as a vaccine adjuvant elicits greater humoral and cellular immune responses to both particulate and soluble antigens. J. Immunol. 2000. 164: 5583-5589.
    • (2000) J. Immunol. , vol.164 , pp. 5583-5589
    • El Mir, S.1    Triebel, F.2
  • 21
    • 0030009494 scopus 로고    scopus 로고
    • Independent modes of natural killing distinguished in mice lacking LAG 3
    • Miyazaki, T., Dierich, A., Benoist, C. and Mathis, D., Independent modes of natural killing distinguished in mice lacking LAG 3. Science 1996. 272: 405-408.
    • (1996) Science , vol.272 , pp. 405-408
    • Miyazaki, T.1    Dierich, A.2    Benoist, C.3    Mathis, D.4
  • 23
  • 24
    • 13344270890 scopus 로고
    • Altered T cell receptor signaling and disrupted T cell development in mice lacking ltk
    • Liao, X. C. and Littman, D. R., Altered T cell receptor signaling and disrupted T cell development in mice lacking ltk. Immunity 1995. 3: 757-769.
    • (1995) Immunity , vol.3 , pp. 757-769
    • Liao, X.C.1    Littman, D.R.2
  • 25
    • 0030740572 scopus 로고    scopus 로고
    • Normal thymic selection, normal viability and decreased lymphoproliferation in T cell receptor-transgenic CTLA-4-deficient mice
    • Waterhouse, P., Bachmann, M. F., Penninger, J. M., Ohashi, P. S. and Mak, T. W., Normal thymic selection, normal viability and decreased lymphoproliferation in T cell receptor-transgenic CTLA-4-deficient mice. Eur. J. Immunol. 1997. 27: 1887-1892.
    • (1997) Eur. J. Immunol. , vol.27 , pp. 1887-1892
    • Waterhouse, P.1    Bachmann, M.F.2    Penninger, J.M.3    Ohashi, P.S.4    Mak, T.W.5
  • 27
    • 0024577093 scopus 로고
    • The V beta-specific superantigen staphylococcal enterotoxin B: Stimulation of mature T cells and clonal deletion in neonatal mice
    • White, J., Herman, A., Pullen, A. M., Kubo, R., Kappler, J. W. and Marrack, P., The V beta-specific superantigen staphylococcal enterotoxin B: stimulation of mature T cells and clonal deletion in neonatal mice. Cell 1989. 56: 27-35.
    • (1989) Cell , vol.56 , pp. 27-35
    • White, J.1    Herman, A.2    Pullen, A.M.3    Kubo, R.4    Kappler, J.W.5    Marrack, P.6
  • 28
    • 0027229409 scopus 로고
    • How do T cell receptors, MHC molecules and superantigens get together?
    • Woodland, D. L. and Blackman, M. A., How do T cell receptors, MHC molecules and superantigens get together? Immunol. Today 1993. 14: 208-212.
    • (1993) Immunol. Today , vol.14 , pp. 208-212
    • Woodland, D.L.1    Blackman, M.A.2
  • 29
    • 0028982226 scopus 로고
    • Contribution of the TCRα-chain to the differential recognition of bacterial and retroviral superantigens
    • Daly, K., Nguyen, P., Hankley, D., Zhang, W. J., Woodland, D. L. and Blackman, M. A., Contribution of the TCRα-chain to the differential recognition of bacterial and retroviral superantigens. J. Immunol. 1995. 155: 27-34.
    • (1995) J. Immunol. , vol.155 , pp. 27-34
    • Daly, K.1    Nguyen, P.2    Hankley, D.3    Zhang, W.J.4    Woodland, D.L.5    Blackman, M.A.6
  • 30
    • 0031015219 scopus 로고    scopus 로고
    • Why do super-antigens care about peptides?
    • Woodland, D. L., Wen, R. and Blackman, M. A., Why do super-antigens care about peptides? Immunol. Today 1997. 18: 18-22.
    • (1997) Immunol. Today , vol.18 , pp. 18-22
    • Woodland, D.L.1    Wen, R.2    Blackman, M.A.3
  • 31
    • 0031897801 scopus 로고    scopus 로고
    • Defective TCR expression in transgenic mice constructed using cDNA-based alpha- and beta-chain genes under the control of heterologous regulatory elements
    • Barnden, M. J., Allison, J., Heath, W. R. and Carbone, F. R., Defective TCR expression in transgenic mice constructed using cDNA-based alpha- and beta-chain genes under the control of heterologous regulatory elements. Immunol. Cell. Biol. 1998. 76: 34-40.
    • (1998) Immunol. Cell. Biol. , vol.76 , pp. 34-40
    • Barnden, M.J.1    Allison, J.2    Heath, W.R.3    Carbone, F.R.4
  • 32
    • 0037111520 scopus 로고    scopus 로고
    • Cutting Edge: The CD4-related molecule, LAG-3, regulates the expansion of activated T cells
    • Workman, C. J., Dugger, K. J. and Vignali, D. A. A., Cutting Edge: The CD4-related molecule, LAG-3, regulates the expansion of activated T cells. J. Immunol. 2002. 169: 5392-5395.
    • (2002) J. Immunol. , vol.169 , pp. 5392-5395
    • Workman, C.J.1    Dugger, K.J.2    Vignali, D.A.A.3
  • 33
    • 0030921664 scopus 로고    scopus 로고
    • Retroviral-mediated transfer of the green fluorescent protein gene into murine hematopoietic cells facilitates scoring and selection of transduced progenitors in vitro and identification of genetically modified cells in vivo
    • Persons, D. A., Allay, J. A., Allay, E. R., Smeyne, R. J., Ashmun, R. A., Sorrentino, B. P. and Nienhuis, A. W., Retroviral-mediated transfer of the green fluorescent protein gene into murine hematopoietic cells facilitates scoring and selection of transduced progenitors in vitro and identification of genetically modified cells in vivo. Blood 1997. 90: 1777-1786.
    • (1997) Blood , vol.90 , pp. 1777-1786
    • Persons, D.A.1    Allay, J.A.2    Allay, E.R.3    Smeyne, R.J.4    Ashmun, R.A.5    Sorrentino, B.P.6    Nienhuis, A.W.7
  • 36
    • 0029009255 scopus 로고
    • LckBP1, a proline-rich protein expressed in haematopoietic lineage cells, directly associates with the SH3 domain of protein tyrosine kinase p56lck
    • Takemoto, Y., Furuta, M., Li, X. K., Strong-Sparks, W. J. and Hashimoto, Y., LckBP1, a proline-rich protein expressed in haematopoietic lineage cells, directly associates with the SH3 domain of protein tyrosine kinase p56lck. EMBO J. 1995. 14: 3403-3414.
    • (1995) EMBO J. , vol.14 , pp. 3403-3414
    • Takemoto, Y.1    Furuta, M.2    Li, X.K.3    Strong-Sparks, W.J.4    Hashimoto, Y.5
  • 37
    • 0028345096 scopus 로고
    • Identification of a protein, SPY75, with repetitive helix-turn-helix motifs and an SH3 domain as a major substrate for protein tyrosine kinase(s) activated by Fc epsilon RI cross-linking
    • Fukamachi, H., Yamada, N., Miura, T., Kato, T., Ishikawa, M., Gulbins, E., Altman, A., Kawakami, Y. and Kawakami, T., Identification of a protein, SPY75, with repetitive helix-turn-helix motifs and an SH3 domain as a major substrate for protein tyrosine kinase(s) activated by Fc epsilon RI cross-linking. J. Immunol. 1994. 152: 642-652.
    • (1994) J. Immunol. , vol.152 , pp. 642-652
    • Fukamachi, H.1    Yamada, N.2    Miura, T.3    Kato, T.4    Ishikawa, M.5    Gulbins, E.6    Altman, A.7    Kawakami, Y.8    Kawakami, T.9
  • 38
    • 0034771834 scopus 로고    scopus 로고
    • LAP, a lymphocyte activation gene-3 (LAG-3)-associated protein that binds to a repeated EP motif in the intracellular region of LAG-3, may participate in the down-regulation of the CD3/TCR activation pathway
    • Iouzalen, N., Andreae, S., Hannier, S. and Triebel, F., LAP, a lymphocyte activation gene-3 (LAG-3)-associated protein that binds to a repeated EP motif in the intracellular region of LAG-3, may participate in the down-regulation of the CD3/TCR activation pathway. Eur. J. Immunol. 2001. 31: 2885-2891.
    • (2001) Eur. J. Immunol. , vol.31 , pp. 2885-2891
    • Iouzalen, N.1    Andreae, S.2    Hannier, S.3    Triebel, F.4
  • 39
    • 0029953858 scopus 로고    scopus 로고
    • CTLA-4 ligation blocks CD28-dependent T cell activation
    • Walunas, T. L., Bakker, C. Y. and Bluestone, J. A., CTLA-4 ligation blocks CD28-dependent T cell activation. J. Exp. Med. 1996. 183: 2541-2550.
    • (1996) J. Exp. Med. , vol.183 , pp. 2541-2550
    • Walunas, T.L.1    Bakker, C.Y.2    Bluestone, J.A.3
  • 40
    • 0029899783 scopus 로고    scopus 로고
    • CTLA-4 engagement inhibits IL-2 accumulation and cell cycle progression upon activation of resting T cells
    • Krummel, M. F. and Allison, J. P., CTLA-4 engagement inhibits IL-2 accumulation and cell cycle progression upon activation of resting T cells. J. Exp. Med. 1996. 183: 2533-2540.
    • (1996) J. Exp. Med. , vol.183 , pp. 2533-2540
    • Krummel, M.F.1    Allison, J.P.2
  • 42
    • 0033083414 scopus 로고    scopus 로고
    • Profound enhancement of T cell activation mediated by the interaction between the T cell receptor and the D3 domain of CD4
    • Vignali, D. A. A. and Vignali, K. M., Profound enhancement of T cell activation mediated by the interaction between the T cell receptor and the D3 domain of CD4. J. Immunol. 1999. 162: 1431-1439.
    • (1999) J. Immunol. , vol.162 , pp. 1431-1439
    • Vignali, D.A.A.1    Vignali, K.M.2
  • 43
    • 0032104669 scopus 로고    scopus 로고
    • An improved method for generating retroviral producer clones for vectors lacking a selectable marker gene
    • Persons, D. A., Mehaffey, M. G., Kaleko, M., Nienhuis, A. W. and Vanin, E. F., An improved method for generating retroviral producer clones for vectors lacking a selectable marker gene. Blood Cells Mol. Dis. 1998. 24: 167-182.
    • (1998) Blood Cells Mol. Dis. , vol.24 , pp. 167-182
    • Persons, D.A.1    Mehaffey, M.G.2    Kaleko, M.3    Nienhuis, A.W.4    Vanin, E.F.5
  • 44
    • 0023871422 scopus 로고
    • A safe packaging line for gene transfer: Separating viral genes on two different plasmids
    • Markowitz, D., Goff, S. and Bank, A., A safe packaging line for gene transfer: separating viral genes on two different plasmids. J. Virol. 1988. 62: 1120-1124.
    • (1988) J. Virol. , vol.62 , pp. 1120-1124
    • Markowitz, D.1    Goff, S.2    Bank, A.3
  • 45
    • 0030802693 scopus 로고    scopus 로고
    • T cell receptor recognition of MHC class II-bound peptide flanking residues enhances immunogenicity and results in altered TCR V region usage
    • Carson, R. T., Vignali, K. M., Woodland, D. L. and Vignali, D. A. A., T cell receptor recognition of MHC class II-bound peptide flanking residues enhances immunogenicity and results in altered TCR V region usage. Immunity 1997. 7: 387-399.
    • (1997) Immunity , vol.7 , pp. 387-399
    • Carson, R.T.1    Vignali, K.M.2    Woodland, D.L.3    Vignali, D.A.A.4
  • 46
    • 0032856945 scopus 로고    scopus 로고
    • Simultaneous quantitation of fifteen cytokines using a multiplexed flow cytometric assay
    • Carson, R. T. and Vignali, D. A. A., Simultaneous quantitation of fifteen cytokines using a multiplexed flow cytometric assay. J. Immunol. Methods 1999. 227: 41-52.
    • (1999) J. Immunol. Methods , vol.227 , pp. 41-52
    • Carson, R.T.1    Vignali, D.A.A.2
  • 47
    • 0032506129 scopus 로고    scopus 로고
    • + T cells in the liver during the control and resolution phases of influenza pneumonia
    • + T cells in the liver during the control and resolution phases of influenza pneumonia. Proc. Natl. Acad. Sci. USA 1998. 95: 13812-13817.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 13812-13817
    • Beiz, G.T.1    Altman, J.D.2    Doherty, R.C.3
  • 48
    • 0029056481 scopus 로고
    • Retroviral transduction and expression of the human alkyl-transferase cDNA provides nitrosourea resistance to hematopoietic cells
    • Allay, J. A., Dumenco, L. L., Koc, O. N., Liu, L. and Gerson, S. L., Retroviral transduction and expression of the human alkyl-transferase cDNA provides nitrosourea resistance to hematopoietic cells. Blood 1995. 85: 3342-3351.
    • (1995) Blood , vol.85 , pp. 3342-3351
    • Allay, J.A.1    Dumenco, L.L.2    Koc, O.N.3    Liu, L.4    Gerson, S.L.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.