Immune dysregulation, polyendocrinopathy, enteropathy, and X-linked inheritance (IPEX), a syndrome of systemic autoimmunity caused by mutations of FOXP3, a critical regulator of T-cell homeostasis

Current Opinion in Rheumatology

Volumn 15, Issue 4, 2003, Pages 430-435

  Gambineri, Eleonora ^a,b   Torgerson, Troy R ^a   Ochs, Hans D ^a,c  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF FLORENCE   (Italy)

^c UNIVERSITY OF WASHINGTON   (United States)

Author keywords

Autoimmunity; CD4+CD25+ regulatory T lymphocytes; Enteropathy; FOXP3; Immune dysfunction; IPEX; Polyendocrinopathy; Scurfy mouse

Indexed keywords

CD4 ANTIGEN; INTERLEUKIN 2 RECEPTOR;

AUTOIMMUNE DISEASE; CHROMOSOME XP; CLINICAL FEATURE; DIARRHEA; DNA BINDING; ENTEROPATHY; GENE EXPRESSION; GENE MAPPING; GENE MUTATION; GENETIC CODE; HOMEOSTASIS; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM; REVIEW; T LYMPHOCYTE; T LYMPHOCYTE SUBPOPULATION; THYROID DISEASE; X CHROMOSOME LINKAGE;

ANIMALS; DNA-BINDING PROTEINS; FORKHEAD TRANSCRIPTION FACTORS; GENETIC DISEASES, X-LINKED; HOMEOSTASIS; HUMANS; IMMUNE SYSTEM; MICE; MUTATION; POLYENDOCRINOPATHIES, AUTOIMMUNE; PROTEIN-LOSING ENTEROPATHIES; SYNDROME; T-LYMPHOCYTES; X CHROMOSOME;

EID: 0038434099     PISSN: 10408711     EISSN: None     Source Type: Journal    
DOI: 10.1097/00002281-200307000-00010     Document Type: Review

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