The codon 72 polymorphic variants of p53 have markedly different apoptotic potential

Nature Genetics

Volumn 33, Issue 3, 2003, Pages 357-365

  Dumont, Patrick ^a   Leu, J I Ju ^b   Della Pietra III, Anthony C ^a   George, Donna L ^b   Murphy, Maureen ^a  

^a FOX CHASE CANCER CENTER   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME C; DACTINOMYCIN; DNA FRAGMENT; HEAT SHOCK PROTEIN 60; LEPTOMYCIN B; LIPOCORTIN 5; PROTEIN MDM2; PROTEIN P53;

AGAR GEL ELECTROPHORESIS; AMINO ACID SEQUENCE; APOPTOSIS; ARTICLE; CANCER; CELL LINE; CELL STRAIN HL 60; CELL STRAIN SAOS 2; CODON; CONTROLLED STUDY; CYTOSOL; DNA POLYMORPHISM; ENZYME RELEASE; GENE REPRESSION; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; MITOCHONDRION; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS; TEMPERATURE SENSITIVE CLONE; TRANSACTIVATION; WESTERN BLOTTING;

APOPTOSIS; ARGININE; CELL LINE; CHAPERONIN 60; CODON; FATTY ACIDS, UNSATURATED; GENES, P53; HSP70 HEAT-SHOCK PROTEINS; HUMANS; MEMBRANE PROTEINS; MITOCHONDRIA; NEOPLASMS; POLYMORPHISM, GENETIC; PROLINE; SUPPRESSION, GENETIC; TRANS-ACTIVATION (GENETICS); TUMOR SUPPRESSOR PROTEIN P53; UBIQUITIN; VARIATION (GENETICS);

EID: 0037372005     PISSN: 10614036     EISSN: None     Source Type: Journal    
DOI: 10.1038/ng1093     Document Type: Article

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