ATM-dependent phosphorylation of Mdm2 on serine 395: Role in p53 activation by DNA damage

Genes and Development

Volumn 15, Issue 9, 2001, Pages 1067-1077

  Maya, Ruth ^a   Balass, Moshe ^a   Kim, Seong Tae ^b   Shkedy, Dganit ^c   Martinez Leal, Juan Fernando ^a   Shifman, Ohad ^a   Moas, Miri ^a   Buschmann, Thomas ^d   Ronai, Ze'ev ^d   Shiloh, Yosef ^c   Kastan, Michael B ^b   Katzir, Ephraim ^a   Oren, Moshe ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^b ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^c TEL AVIV UNIVERSITY   (Israel)

^d MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

Nucleo cytoplasmic shuttling; Proteolysis; Radiation; Ubiquitination

Indexed keywords

ATM PROTEIN; EPITOPE; MONOCLONAL ANTIBODY; PROTEIN MDM2; PROTEIN P53; SERINE;

ARTICLE; CARBOXY TERMINAL SEQUENCE; DNA DAMAGE; GENOTOXICITY; HUMAN; HUMAN CELL; IONIZING RADIATION; MOLECULAR RECOGNITION; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION;

AMINO ACID SUBSTITUTION; ANIMALS; ANTIBODIES, MONOCLONAL; ASPARTIC ACID; CELL CYCLE PROTEINS; CELL NUCLEUS; CELLS, CULTURED; DNA DAMAGE; DNA-BINDING PROTEINS; EPITOPE MAPPING; FIBROBLASTS; HUMANS; MICE; MICROINJECTIONS; MUTATION; NUCLEAR PROTEINS; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-MDM2; SERINE; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS;

EID: 0035339357     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.886901     Document Type: Article

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