Transcriptional repression by wild-type p53 utilizes histone deacetylases, mediated by interaction with mSin3a

Genes and Development

Volumn 13, Issue 19, 1999, Pages 2490-2501

  Murphy, Maureen ^a   Ahn, Jaimo ^b   Walker, Kristen K ^c   Hoffman, William H ^a   Evans, Ronald M ^c   Levine, Arnold J ^d   George, Donna L ^b  

^a FOX CHASE CANCER CENTER   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^d ROCKEFELLER UNIVERSITY   (United States)

Author keywords

Apoptosis induction; Gene transcription; p53 protein; Transcriptional repression

Indexed keywords

HISTONE DEACETYLASE; PROTEIN P53; STATHMIN; TRICHOSTATIN A;

ANIMAL CELL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; EMBRYO; GENE ACTIVATION; GENE CONTROL; GENE FUNCTION; GENE INDUCTION; GENE REPRESSION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN PROTEIN INTERACTION; TRANSCRIPTION REGULATION;

ANIMALS; APOPTOSIS; BINDING SITES; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLINS; DNA DAMAGE; ENZYME INHIBITORS; GENE EXPRESSION REGULATION; HISTONE DEACETYLASES; HUMANS; HYDROXAMIC ACIDS; MICE; MICROTUBULE PROTEINS; MICROTUBULE-ASSOCIATED PROTEINS; MUTAGENESIS; NUCLEAR PROTEINS; PHOSPHOPROTEINS; PROMOTER REGIONS (GENETICS); PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-MDM2; REPRESSOR PROTEINS; STATHMIN; TRANSCRIPTION, GENETIC; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEIN P53;

ANIMALIA;

EID: 0033215387     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.13.19.2490     Document Type: Article

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