p53 inhibitor pifithrin α can suppress heat shock and glucocorticoid signaling pathways

Journal of Biological Chemistry

Volumn 278, Issue 18, 2003, Pages 15465-15468

  Komarova, Elena A ^a   Neznanov, Nickolay ^a   Komarov, Pavel G ^b   Chernov, Mikhail V ^a   Wang, Kaihua ^b   Gudkov, Andrei V ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

^b Quark Biotech Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMICAL ENGINEERING; CHEMICAL ACTIVATION; MOLECULAR BIOLOGY; THERMAL EFFECTS;

CHEMICAL PATHWAYS;

ANIMAL CELL CULTURE;

DEXAMETHASONE; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; HEAT SHOCK TRANSCRIPTION FACTOR 1; PIFITHRIN ALPHA; PROTEIN INHIBITOR; PROTEIN P53; UNCLASSIFIED DRUG; BENZOTHIAZOLE DERIVATIVE; DNA BINDING PROTEIN; DRUG DERIVATIVE; HEAT SHOCK TRANSCRIPTION FACTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PIFITHRIN; THIAZOLE DERIVATIVE; TOLUENE; TRANSCRIPTION FACTOR;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL FUNCTION; CONTROLLED STUDY; GAMMA RADIATION; HEAT SHOCK; MOLECULAR INTERACTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ISOLATION; SIGNAL TRANSDUCTION; TRANSACTIVATION; ANIMAL; BIOSYNTHESIS; DRUG ANTAGONISM; DRUG EFFECT; HEAT SHOCK RESPONSE; METABOLISM; PHYSIOLOGY;

ANIMALIA;

ANIMALS; BENZOTHIAZOLES; DNA-BINDING PROTEINS; GLUCOCORTICOIDS; HEAT-SHOCK RESPONSE; MICE; NF-KAPPA B; RECEPTORS, GLUCOCORTICOID; SIGNAL TRANSDUCTION; THIAZOLES; TOLUENE; TRANSCRIPTION FACTORS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0037507247     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.C300011200     Document Type: Article

References (27)

1. Komarova, E. A., and Gudkov, A. V. (1998) Semin. Cancer Biol. 8, 389-400
2. Komarov, P. G., Komarova, E. A., Kondratov, R. V., Christov-Tselkov, K., Coon, J. S. Chernov, M. V., and Gudkov, A. V. (1999) Science 285, 1733-1737
3. Komarova, E. A., and Gudkov, A. V. (2001) Biochem. Pharmacol 62, 657-667
4. Culmsee, C., Zhu, X., Yu, Q. S., Chan, S. L., Camandola, S., Guo, Z., Greig, N. H., and Mattson, M. P. (2001) J. Neurochem. 77, 220-228
5. Zhu, X., Yu, Q. S., Cutler, R. G., Culmsee, C. W., Holloway, H. W., Lahiri, D. K., Mattson, M. P., and Greig, N. H. (2002) J. Med. Chem. 45, 5090-5097
6. Duan, W., Zhu, X., Ladenheim, B., Yu, Q. S., Guo, Z., Oyler, J., Cutler, R. G., Cadet, J. L., Greig, N. H., and Mattson, M. P. (2002) Ann. Neurol. 52, 597-606
7. Kelly, K. J., Plotkin, Z., Vulgamott, S. L., and Dagher, P. C. (2003) J. Am. Soc. Nephrol. 14, 128-138
8. Bunz, F., Dutriaux, A., Lengauer, C., Waldman, T., Zhou, S., Brown, J. P., Sedivy, J. M., Kinzler, K. W., and Vogelstein, B. (1998) Science 282, 1497-1501
9. Neznanov, N., Kondratova, A., Chumakov, K. M., Angres, B., Zhumabayeva, B., Agol, V. I., and Gudkov, A. V. (2001) J. Virol. 75, 10409-10420
10. Truss, M., Chalepakis, G., Slater, E. P., Mader, S., and Beato, M. (1991) Mol. Cell. Biol, 11, 3247-3258
11. Galang, C. K., Garcia-Ramirez, J., Solski, P. A., Westwick, J. K., Der, C. J., Neznanov, N. N., Oshima, R. G., and Hauser, C. A. (1996) J. Biol. Chem. 271, 7992-7998
12. Williams, G. T., and Morimoto, R. I. (1990) Mol. Cell. Biol. 10, 3125-3136
13. Kondratov, R. V., Kuznetsov, N. V., Pugacheva, E. N., Almazov, V. P., Prasolov, V. S., Kopnin, B. P., and Chumakov, P. M. (1996) Mol. Biol. (Engl. Transl. Mol. Biol. (Mosc.)) 30, 613-620
14. Pirkkala, L., Nykanen, P., and Sistonen, L. (2001) FASEB J. 15, 1118-1131
15. Morimoto,R. I., Kroeger, P. E., and Cotto, J. J. (1996) EXS (Basel) 77, 139-163
16. Jolly, C., and Morimoto, R. I. (2000) J. Natl. Cancer Inst. 92, 1564-1572
17. Gordon, S. A., Hoffman, R. A., Simmons, R. L., and Ford, H. R. (1997) Arch. Surg. 132, 1277-1282
18. Hache, R. J., Tse, R., Reich, T., Savory, J. G., and Lefebvre, Y. A. (1999) J. Biol. Chem. 274, 1432-1439
19. Winoto, A., and Littman, D. R. (2002) Cell 109, (suppl.) S57-S66
20. Lowe, S. W., Schmitt, E. M., Smith, S. W., Osborne, B. A., and Jacks, T. (1993) Nature 362, 847-849
21. Gerondakis, S., Grumont, R., Rourke, I., and Grossmann, M., (1998) Curr. Opin. Immunol. 10, 353-359
22. Li, X., and Stark, G. R. (2002) Exp. Hematol. 30, 285-296
23. Natoli, G., Costanzo, A., Guido, F., Moretti, F., Bernardo, A., Burgio, V. L., Agresti, C., and Levrero, M. (1998) J. Biol. Chem. 273, 31262-31272
24. Nakanoma, T., Ueno, M., Iida, M., Hirata, R., and Deguchi, N. (2001) Int. J. Urol. 8, 623-630
25. Beere, H. M. (2001) Sci STKE http://stke.sciencemag.org/cgi/content/full/sigtrans;2001/93/RE1
26. Chen, Y. C., Lin-Shiau, S. Y., and Lin, J. K. (1999) Photochem. Photobiol. 70, 78-86
27. Jakubowicz-Gil, J., Rzymowska, J., and Gawron, A. (2002) Biochem. Pharmacol. 64, 1591-1595