Restoration of the tumor suppressor function to mutant p53 by a low-molecular-weight compound

Nature Medicine

Volumn 8, Issue 3, 2002, Pages 282-288

  Bykov, Vladimir J N ^a   Issaeva, Natalia ^a   Shilov, Alexandre ^a,b   Hultcrantz, Monica ^a   Pugacheva, Elena ^c   Chumakov, Peter ^c   Bergman, Jan ^d   Wiman, Klas G ^a   Selivanova, Galina ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b INSTITUTE OF CYTOLOGY AND GENETICS   (Russian Federation)

^c ENGELHARDT INSTITUTE OF MOLECULAR BIOLOGY   (Russian Federation)

^d KAROLINSKA INSTITUTE   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

GENE PRODUCT; PROTEIN P53; PROTEIN PRIMA 1; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DNA BINDING; DNA LIBRARY; DNA SEQUENCE; DOSE RESPONSE; GENE ACTIVATION; GENE MUTATION; GENE THERAPY; HUMAN; HUMAN CELL; MOLECULAR WEIGHT; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; TRANSCRIPTION REGULATION; TUMOR CELL CULTURE; TUMOR SUPPRESSOR GENE;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; AZA COMPOUNDS; BICYCLO COMPOUNDS, HETEROCYCLIC; CELL SEPARATION; FLOW CYTOMETRY; GENES, REPORTER; HUMANS; IN SITU NICK-END LABELING; MICE; MOLECULAR STRUCTURE; MOLECULAR WEIGHT; MUTATION; NEOPLASMS; ORGANIC CHEMICALS; PROTEIN CONFORMATION; TRANS-ACTIVATION (GENETICS); TRANSPLANTATION, HETEROLOGOUS; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEIN P53;

ANIMALIA;

EID: 0036128899     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/nm0302-282     Document Type: Article

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