p53 binds and activates the xeroderma pigmentosum DDB2 gene in humans but not mice

Molecular and Cellular Biology

Volumn 22, Issue 10, 2002, Pages 3247-3254

  Tan, Thomas ^a   Chu, Gilbert ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOBUTANE; PROTEIN P53; PYRIMIDINE DIMER;

ANIMAL CELL; ARTICLE; BIOACCUMULATION; CANCER SUSCEPTIBILITY; DDB2 GENE; DNA DAMAGE; DNA REPAIR; GENE; GENE ACTIVATION; GENE FUNCTION; GENE LOCUS; GENE MUTATION; GENE SEQUENCE; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN FUNCTION; SEQUENCE HOMOLOGY; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION; ULTRAVIOLET RADIATION; XERODERMA PIGMENTOSUM;

ANIMALS; BASE SEQUENCE; CELL LINE; DNA REPAIR; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION; GENES, REPORTER; HUMANS; MICE; MOLECULAR SEQUENCE DATA; RESPONSE ELEMENTS; TRANSCRIPTION, GENETIC; TUMOR SUPPRESSOR PROTEIN P53; ULTRAVIOLET RAYS; XERODERMA PIGMENTOSUM;

ANIMALIA;

EID: 0036234458     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.22.10.3247-3254.2002     Document Type: Article

References (37)

1. A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells
2. Is p53 polymorphism maintained by natural selection?
3. p21-induced cycle arrest in G1 protects cells from apoptosis induced by UV-irradiation or RNA polymerase II blockage
4. DNA repair in an active gene: Removal of pyrimidine dimers from the DHFR gene of CHO cells is much more efficient than in the genome overall
5. Xeroderma pigmentosum group E cells lack a nuclear factor that binds to damaged DNA
6. Xeroderma pigmentosum
7. Targeting rare populations of murine antigen-specific T lymphocytes by retroviral transduction for potential application in gene therapy for autoimmune disease
8. Chromosomal localization and cDNA cloning of the genes (DDB1 and DDB2) for the p127 and p48 subunits of a human damage-specific DNA binding protein
9. Definition of a consensus binding site for p53
10. WAFI, a potential mediator of p53 tumor suppression
11. Li-Fraumeni syndrome fibroblasts homozygous for p53 mutations are deficient in global DNA repair but exhibit normal transcription-coupled repair and enhanced UV resistance
12. Activation of DNA-dependent protein kinase by single-stranded DNA ends
13. Analysis of the mammalian gadd45 gene and its response to DNA damage
14. Regulation of the specific DNA binding function of p53
15. Expression of the p48 xeroderma pigmentosum gene is p53-dependent and is involved in global genomic repair
16. Isolation of a cDNA encoding a UV-damaged-DNA binding factor defective in xeroderma pigmentosum group E cells
17. p48 activates a UV-damaged-DNA binding factor and is defective in xeroderma pigmentosum group E cells that lack binding activity
18. A newly identified patient with clinical xeroderma pigmentosum phenotype has a non-sense mutation in the DDB2 gene and incomplete repair in (6-4) photoproducts
19. Biochemical heterogeneity in xeroderma pigmentosum complementation group E
20. Differential DNA repair in transcriptionally active and inactive proto-oncogenes: c-abl and c-mos
21. UV irradiation stimulates levels of p53 cellular tumor antigen in nontransformed mouse cells
22. Primary structure polymorphism at amino acid residue 72 of human p53
23. Selective removal of transcription-blocking DNA damage from the transcribed strand of the mammalian DHFR gene
24. Mutations specific to the xeroderma pigmentosum group E Ddb-phenotype
25. Hepatitis B x protein inhibits p53-dependent DNA repair in primary mouse hepatocytes
26. Functional interaction of wild-type and mutant p53 transfected into human tumor cell lines carrying activated ras genes
27. Restoration of X-ray resistance and V(D)J recombination in mutant cells by Ku cDNA
28. Interaction of the p53-regulated protein gadd45 with proliferating cell nuclear antigen
29. p53-mediated DNA repair responses to UV radiation: Studies of mouse cells lacking p53, p21, and/or gadd45 genes
30. A 127 kDa component of a UV-damaged DNA-binding complex, which is defective in some xeroderma pigmentosum group E patients, is homologous to a slime mold protein
31. Xeroderma pigmentosum complementation group E and UV-damaged DNA binding protein
32. Xeroderma pigmentosum p48 gene enhances global genomic repair and suppresses UV-induced mutagenesis
33. Two polymorphic variants of wild-type p53 differ biochemically and biologically
34. Defective transcription-coupled repair in Cockayne syndrome B mice is associated with skin cancer predisposition
35. Cyclobutane pyrimidine dimers in UV-DNA induce release of soluble mediators that activate the human immunodeficiency virus promoter
36. Studies of the murine DDB1 and DDB2 genes