PAC1 phosphatase is a transcription target of p53 in signalling apoptosis and growth suppression

Nature

Volumn 422, Issue 6931, 2003, Pages 527-531

  Yin, Yuxin ^a   Llu, Yu Xin ^a   Jin, Yan J ^a   Hall, Eric J ^a   Barrett, J Carl ^b  

^a Columbia University ^*  (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GENES; OXIDATION; PROTEINS; TUMORS;

OXIDATIVE STRESS;

CONSERVATION;

MITOGEN ACTIVATED PROTEIN KINASE; PAC1 PHOSPHATASE; PALINDROMIC DNA; PHOSPHATASE; PROTEIN DUSP2; PROTEIN P53; PROTEIN THREONINE TYROSINE PHOSPHATASE; PROTEIN TYROSINE PHOSPHATASE; RNA; UNCLASSIFIED DRUG;

BIOLOGY;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BINDING SITE; CANCER INHIBITION; CELL CYCLE; CONTROLLED STUDY; ENZYME ANALYSIS; ENZYME PHOSPHORYLATION; ENZYME SPECIFICITY; GAMMA IRRADIATION; GENE OVEREXPRESSION; GENE TARGETING; GROWTH INHIBITION; GROWTH REGULATION; HUMAN; HUMAN CELL; MITOSIS INHIBITION; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN MOTIF; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION;

NON-PROGRAMMATIC;

ANIMALS; APOPTOSIS; BASE SEQUENCE; BINDING SITES; CELL DIVISION; DNA; DNA FOOTPRINTING; ELECTROPHORETIC MOBILITY SHIFT ASSAY; MICE; MOLECULAR SEQUENCE DATA; PROMOTER REGIONS (GENETICS); PROTEIN BINDING; PROTEIN-TYROSINE-PHOSPHATASE; SIGNAL TRANSDUCTION; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION, GENETIC; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEIN P53;

ANIMALIA;

EID: 0037417281     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/nature01519     Document Type: Article

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