Tissue specific expression of p53 target genes suggests a key role for KILLER/DR5 in p53-dependent apoptosis in vivo

Oncogene

Volumn 20, Issue 34, 2001, Pages 4601-4612

  Burns, Timothy F ^a   Bernhard, Eric J ^a   El Deiry, Wafik S ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

irradiation; Apoptosis; c FLIP s; KILLER DR5; p53; Real time RT PCR

Indexed keywords

ADENOSINE TRIPHOSPHATE PHOSPHORIBOSYLTRANSFERASE; CASPASE 8; CASPASE 9; CASPASE INHIBITOR; CELL PROTEIN; CELL RECEPTOR; DEXAMETHASONE; MESSENGER RNA; PROTEIN BAX; PROTEIN BCL X; PROTEIN P21; PROTEIN P53; TUMOR NECROSIS FACTOR RECEPTOR; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND;

ADOLESCENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; ENZYME INHIBITION; FEMALE; GAMMA IRRADIATION; GENE INDUCTION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; IONIZING RADIATION; MITOCHONDRION; MOUSE; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SMALL INTESTINE; SPLEEN; THYMUS; TISSUE SPECIFICITY; TRANSACTIVATION;

ANIMALS; ANTIGENS, CD95; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CASPASE 8; CASPASE 9; CASPASES; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLINS; HUMANS; INTESTINE, SMALL; MICE; MICE, KNOCKOUT; MITOCHONDRIA; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; RADIATION, IONIZING; RECEPTORS, TNF-RELATED APOPTOSIS-INDUCING LIGAND; RECEPTORS, TUMOR NECROSIS FACTOR; RNA, MESSENGER; SPLEEN; TRANS-ACTIVATION (GENETICS); TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEIN P53;

ANIMALIA;

EID: 0035797473     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1204484     Document Type: Article

References (54)