-
2
-
-
0033624419
-
Mitochondrial dysfunction and oxidative stress in aging and neurodegenerative disease
-
Albers DS, Beal MF (2000) Mitochondrial dysfunction and oxidative stress in aging and neurodegenerative disease. J Neural Transm [Suppl] 59: 133-154
-
(2000)
J Neural Transm [Suppl]
, vol.59
, pp. 133-154
-
-
Albers, D.S.1
Beal, M.F.2
-
3
-
-
0035120203
-
Further evidence for mitochondrial dysfunction in progressive supranuclear palsy
-
Albers DS, Swerdlow RH, Manfredi G, Gajewski C, Yang L, Parker WD Jr, Beal MF (1999) Further evidence for mitochondrial dysfunction in progressive supranuclear palsy. Exp Neurol 168: 196-198
-
(1999)
Exp Neurol
, vol.168
, pp. 196-198
-
-
Albers, D.S.1
Swerdlow, R.H.2
Manfredi, G.3
Gajewski, C.4
Yang, L.5
Parker Jr., W.D.6
Beal, M.F.7
-
4
-
-
0037127216
-
Tubulin seeds α-synuclein fibril formation
-
Alim MA, Hossain MS, Arima K, Takeda K, Izumiyama Y, Nakamura M, Kaji H, Shinoda T, Hisanaga S, Ueda K (2002) Tubulin seeds α-synuclein fibril formation. J Biol Chem 277: 2112-2117
-
(2002)
J Biol Chem
, vol.277
, pp. 2112-2117
-
-
Alim, M.A.1
Hossain, M.S.2
Arima, K.3
Takeda, K.4
Izumiyama, Y.5
Nakamura, M.6
Kaji, H.7
Shinoda, T.8
Hisanaga, S.9
Ueda, K.10
-
5
-
-
1542641974
-
The pathogenesis of amyotrophic lateral sclerosis
-
Mattson MP (ed) Human Press, Totowa
-
Appel SH, Smith RG (2001) The pathogenesis of amyotrophic lateral sclerosis. In: Mattson MP (ed) Pathogenesis of neurodegenerative disorders. Human Press, Totowa, pp 149-171
-
(2001)
Pathogenesis of Neurodegenerative Disorders
, pp. 149-171
-
-
Appel, S.H.1
Smith, R.G.2
-
6
-
-
0035847186
-
α-Synuclein-positive structures in cases with sporadic Alzheimer's disease: Morphology and its relationship to tau aggregation
-
Arai Y, Yamazaki M, Mori O, Muramatsu H, Asano G, Katayama Y (2001) α-Synuclein-positive structures in cases with sporadic Alzheimer's disease: morphology and its relationship to tau aggregation. Brain Res 888: 287-296
-
(2001)
Brain Res
, vol.888
, pp. 287-296
-
-
Arai, Y.1
Yamazaki, M.2
Mori, O.3
Muramatsu, H.4
Asano, G.5
Katayama, Y.6
-
7
-
-
0036468432
-
Chaperone suppression of α-synuclein toxicity in a Drosophila model for Parkinson's disease
-
Auluck PK, Chan HY, Trojanowski JQ, Lee VM, Bonini NM (2002) Chaperone suppression of α-synuclein toxicity in a Drosophila model for Parkinson's disease. Science 295: 865-868
-
(2002)
Science
, vol.295
, pp. 865-868
-
-
Auluck, P.K.1
Chan, H.Y.2
Trojanowski, J.Q.3
Lee, V.M.4
Bonini, N.M.5
-
8
-
-
0034237719
-
Energetics in the pathogenesis of neurodegenerative diseases
-
Beal MF (2000a) Energetics in the pathogenesis of neurodegenerative diseases. TINS 23: 298-304
-
(2000)
TINS
, vol.23
, pp. 298-304
-
-
Beal, M.F.1
-
9
-
-
0033934734
-
Mitochondria and the pathogenesis of ALS
-
Beal MF (2000b) Mitochondria and the pathogenesis of ALS. Brain 123: 1291-1292
-
(2000)
Brain
, vol.123
, pp. 1291-1292
-
-
Beal, M.F.1
-
10
-
-
0002770493
-
Superoxide dismutase and the death of motoneurons in ALS
-
Beckman JS, Estévez AG, Crow JP, Barbeito L (2001) Superoxide dismutase and the death of motoneurons in ALS. TINS 24 [Suppl]: S15-S20
-
(2001)
TINS
, vol.24
, Issue.SUPPL.
-
-
Beckman, J.S.1
Estévez, A.G.2
Crow, J.P.3
Barbeito, L.4
-
11
-
-
0035947372
-
Impairment of the ubiquitin-protease system by protein aggregation
-
Bence N, Roopal M (2001) Impairment of the ubiquitin-protease system by protein aggregation. Science 292: 1552-1554
-
(2001)
Science
, vol.292
, pp. 1552-1554
-
-
Bence, N.1
Roopal, M.2
-
12
-
-
0035947372
-
Impairment of the ubiquitin-proteasome system by protein aggregation
-
Bence NF, Sampat RM, Kopito RR (2001) Impairment of the ubiquitin-proteasome system by protein aggregation. Science 292: 1552-1555
-
(2001)
Science
, vol.292
, pp. 1552-1555
-
-
Bence, N.F.1
Sampat, R.M.2
Kopito, R.R.3
-
13
-
-
0036710567
-
Glutathione, iron and Parkinson's disease
-
Bharath S, Hsu M, Kaur D, Rajagopalan S, Andersen JK (2002) Glutathione, iron and Parkinson's disease. Biochem Pharmacol 64: 1037-1048
-
(2002)
Biochem Pharmacol
, vol.64
, pp. 1037-1048
-
-
Bharath, S.1
Hsu, M.2
Kaur, D.3
Rajagopalan, S.4
Andersen, J.K.5
-
14
-
-
0034993599
-
Molecular pathways involved in the neurotoxicity of 6-OHDA, dopamine and MPTP: Contribution to the apoptotic theory in Parkinson's disease
-
Blum D, Torch S, Lambeng N, Nissou M, Benabid AL, Sadoul R, Verna JM (2001) Molecular pathways involved in the neurotoxicity of 6-OHDA, dopamine and MPTP: contribution to the apoptotic theory in Parkinson's disease. Prog Neurobiol 65: 135-172
-
(2001)
Prog Neurobiol
, vol.65
, pp. 135-172
-
-
Blum, D.1
Torch, S.2
Lambeng, N.3
Nissou, M.4
Benabid, A.L.5
Sadoul, R.6
Verna, J.M.7
-
15
-
-
0035668684
-
Increased oxidative damage to DNA in a transgenic mouse model of Huntington's disease
-
Bogdanov MB, Andreassen OA, Dedeoglu A, Ferrante RJ, Beal MF (2001) Increased oxidative damage to DNA in a transgenic mouse model of Huntington's disease. J Neurochem 79: 1246-1249
-
(2001)
J Neurochem
, vol.79
, pp. 1246-1249
-
-
Bogdanov, M.B.1
Andreassen, O.A.2
Dedeoglu, A.3
Ferrante, R.J.4
Beal, M.F.5
-
16
-
-
0037176843
-
Increase of cdk5 is related to neurofibrillary pathology in progressive supranuclear palsy
-
Borghi R, Giliberto L, Assini A, Delacourte A, Perry G, Smith MA, Strocchi P, Zaccheo D, Tabaton M (2002) Increase of cdk5 is related to neurofibrillary pathology in progressive supranuclear palsy. Neurology 58: 589-592
-
(2002)
Neurology
, vol.58
, pp. 589-592
-
-
Borghi, R.1
Giliberto, L.2
Assini, A.3
Delacourte, A.4
Perry, G.5
Smith, M.A.6
Strocchi, P.7
Zaccheo, D.8
Tabaton, M.9
-
17
-
-
0032745071
-
Mitochondrial enzyme activity in amyotrophic lateral sclerosis: Implications for the role of mitochondria in neuronal cell death
-
Borthwick GM, Johnson MA, Ince PG, Shaw PJ, Turnbull DM (1999) Mitochondrial enzyme activity in amyotrophic lateral sclerosis: implications for the role of mitochondria in neuronal cell death. Ann Neurol 46: 787-790
-
(1999)
Ann Neurol
, vol.46
, pp. 787-790
-
-
Borthwick, G.M.1
Johnson, M.A.2
Ince, P.G.3
Shaw, P.J.4
Turnbull, D.M.5
-
18
-
-
0037126952
-
Increased tau phosphorylation but absence of formation of neurofibrillary tangles in mice double transgenic for human tau and Alzheimer mutant (M146L) presenilin-1
-
Boutajangout A, Leroy K, Touchet N, Authelet M, Blanchard V, Tremp G, Pradier L, Brion JP (2002) Increased tau phosphorylation but absence of formation of neurofibrillary tangles in mice double transgenic for human tau and Alzheimer mutant (M146L) presenilin-1. Neurosci Lett 318: 29-33
-
(2002)
Neurosci Lett
, vol.318
, pp. 29-33
-
-
Boutajangout, A.1
Leroy, K.2
Touchet, N.3
Authelet, M.4
Blanchard, V.5
Tremp, G.6
Pradier, L.7
Brion, J.P.8
-
19
-
-
0025863618
-
Neuropathological stageing of Alzheimer-related changes
-
Braak H, Braak E (1991) Neuropathological stageing of Alzheimer-related changes. Acta Neuropathol 82: 239-259
-
(1991)
Acta Neuropathol
, vol.82
, pp. 239-259
-
-
Braak, H.1
Braak, E.2
-
20
-
-
0035368563
-
Apoptotic death sensor: An organelle's alter ego?
-
Bratton SB, Cohen GM (2001) Apoptotic death sensor: an organelle's alter ego? Trends Pharmacol Sci 22: 306-315
-
(2001)
Trends Pharmacol Sci
, vol.22
, pp. 306-315
-
-
Bratton, S.B.1
Cohen, G.M.2
-
21
-
-
0037041420
-
Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases
-
Bucciantini M, Giannoni E, Chiti F, Baroni F, Formigli L, Zurdo J, Taddei N, Ramponi G, Dobson CM, Stefani M (2002) Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases. Nature 416: 507-511
-
(2002)
Nature
, vol.416
, pp. 507-511
-
-
Bucciantini, M.1
Giannoni, E.2
Chiti, F.3
Baroni, F.4
Formigli, L.5
Zurdo, J.6
Taddei, N.7
Ramponi, G.8
Dobson, C.M.9
Stefani, M.10
-
23
-
-
0036905921
-
Amyloid β-peptide (1-42)-induced oxidative stress and neurotoxicity: Implications for neurodegeneration in Alzheimer disease brain
-
Butterfield D (2002) Amyloid β-peptide (1-42)-induced oxidative stress and neurotoxicity: Implications for neurodegeneration in Alzheimer disease brain. Free Radic Res 36: 1307-1313
-
(2002)
Free Radic Res
, vol.36
, pp. 1307-1313
-
-
Butterfield, D.1
-
24
-
-
0031830710
-
Induction of nitric oxide synthase and microglial responses precede selective cell death induced by chronic impairment of oxidative metabolism
-
Calingasan NY, Park LC, Calo LL, Trifiletti RR, Gandy SE, Gibson GE (1998) Induction of nitric oxide synthase and microglial responses precede selective cell death induced by chronic impairment of oxidative metabolism. Am J Pathol 153: 599-610
-
(1998)
Am J Pathol
, vol.153
, pp. 599-610
-
-
Calingasan, N.Y.1
Park, L.C.2
Calo, L.L.3
Trifiletti, R.R.4
Gandy, S.E.5
Gibson, G.E.6
-
25
-
-
0037039837
-
Hydroxynonenal adducts indicate a role for lipid peroxidation in neocortical and brainstem Lewy bodies in humans
-
Castellani RJ, Perry G, Siedlak SL, Nunomura A, Shimohama S, Zhang J, Montine T, Sayre LM, Smith MA (2002) Hydroxynonenal adducts indicate a role for lipid peroxidation in neocortical and brainstem Lewy bodies in humans. Neurosci Lett 319: 25-8
-
(2002)
Neurosci Lett
, vol.319
, pp. 25-28
-
-
Castellani, R.J.1
Perry, G.2
Siedlak, S.L.3
Nunomura, A.4
Shimohama, S.5
Zhang, J.6
Montine, T.7
Sayre, L.M.8
Smith, M.A.9
-
27
-
-
0035282594
-
Loss of normal huntingtin function: New developments in Huntington's disease research
-
Cattaneo E, Rigamonti D, Goffredo D, Zuccato C, Squitieri F, Sipione S (2001) Loss of normal huntingtin function: new developments in Huntington's disease research. Trends Neurosci 24: 182-188
-
(2001)
Trends Neurosci
, vol.24
, pp. 182-188
-
-
Cattaneo, E.1
Rigamonti, D.2
Goffredo, D.3
Zuccato, C.4
Squitieri, F.5
Sipione, S.6
-
28
-
-
0034703863
-
Mechanisms of chaperone suppression of polyglutamine disease: Selectivity, synergy and modulation of protein solubility in Drosophila
-
Chan HY, Warrick JM, Gray-Board GL, Paulson HL, Bonini NM (2000) Mechanisms of chaperone suppression of polyglutamine disease: selectivity, synergy and modulation of protein solubility in Drosophila. Hum Mol Genet 9: 2811-2820
-
(2000)
Hum Mol Genet
, vol.9
, pp. 2811-2820
-
-
Chan, H.Y.1
Warrick, J.M.2
Gray-Board, G.L.3
Paulson, H.L.4
Bonini, N.M.5
-
29
-
-
0037059069
-
Studies of the aggregation of mutant proteins in vitro provide insights into the genetics of amyloid diseases
-
Chiti F, Calamai M, Taddei N, Stefani M, Ramponi G, Dobson CM (2002) Studies of the aggregation of mutant proteins in vitro provide insights into the genetics of amyloid diseases. Proc Natl Acad Sci USA 99 Suppl 4: 16419-16426
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, Issue.4 SUPPL.
, pp. 16419-16426
-
-
Chiti, F.1
Calamai, M.2
Taddei, N.3
Stefani, M.4
Ramponi, G.5
Dobson, C.M.6
-
30
-
-
2942618660
-
The role of the ubiquitin-proteasomal pathway in Parkinson's disease and other neurodegenerative disorders
-
Chung KKK, Dawson VL, Dawson TM (2001) The role of the ubiquitin-proteasomal pathway in Parkinson's disease and other neurodegenerative disorders. TINS 24 [Suppl]: S7-S14
-
(2001)
TINS
, vol.24
, Issue.SUPPL.
-
-
Chung, K.K.K.1
Dawson, V.L.2
Dawson, T.M.3
-
31
-
-
0036135523
-
Protein crosslinking, tissue transglutaminase, alternative splicing and neurodegeneration
-
Citron BA, Suo Z, SantaCruz K, Davies PJ, Qin F, Festoff BW (2001) Protein crosslinking, tissue transglutaminase, alternative splicing and neurodegeneration. Neurochem Int 40: 69-78
-
(2001)
Neurochem Int
, vol.40
, pp. 69-78
-
-
Citron, B.A.1
Suo, Z.2
SantaCruz, K.3
Davies, P.J.4
Qin, F.5
Festoff, B.W.6
-
32
-
-
0034644203
-
A one-hit model of cell death in inherited neuronal degenerations
-
Clarke G, Collins RA, Leavitt BR, Andrews DF, Hayden MR, Lumsden CJ, McInnes RR (2000) A one-hit model of cell death in inherited neuronal degenerations. Nature 406: 195-199
-
(2000)
Nature
, vol.406
, pp. 195-199
-
-
Clarke, G.1
Collins, R.A.2
Leavitt, B.R.3
Andrews, D.F.4
Hayden, M.R.5
Lumsden, C.J.6
McInnes, R.R.7
-
33
-
-
0033215063
-
Synucleins in synaptic plasticity and neurodegenerative disorders
-
Clayton DF, George JM (1999) Synucleins in synaptic plasticity and neurodegenerative disorders. J Neurosci Res 58: 120-129
-
(1999)
J Neurosci Res
, vol.58
, pp. 120-129
-
-
Clayton, D.F.1
George, J.M.2
-
34
-
-
0035666597
-
Mechanisms of neurodegeneration in amyotrophic lateral sclerosis
-
Cluskey S, Ramsden DB (2001) Mechanisms of neurodegeneration in amyotrophic lateral sclerosis. Mol Pathol 54: 386-392
-
(2001)
Mol Pathol
, vol.54
, pp. 386-392
-
-
Cluskey, S.1
Ramsden, D.B.2
-
35
-
-
0000982585
-
Progressive supranuclear palsy and corticobasal degeneration
-
Hof RR, Mobbs LCK (eds) Academic Press, San Diego
-
Dickson DW (2001) Progressive supranuclear palsy and corticobasal degeneration. In: Hof RR, Mobbs LCK (eds) Functional neurobiology of aging. Academic Press, San Diego, pp 155-171
-
(2001)
Functional Neurobiology of Aging
, pp. 155-171
-
-
Dickson, D.W.1
-
36
-
-
0034984011
-
Apoptosis in the in vivo mammalian forebrain
-
Dikranian K, Ishimaru MJ, Tenkova T, Labruyere J, Qin YQ, Ikonomidou C, Olney JW (2001) Apoptosis in the in vivo mammalian forebrain. Neurobiol Dis 8: 359-379
-
(2001)
Neurobiol Dis
, vol.8
, pp. 359-379
-
-
Dikranian, K.1
Ishimaru, M.J.2
Tenkova, T.3
Labruyere, J.4
Qin, Y.Q.5
Ikonomidou, C.6
Olney, J.W.7
-
37
-
-
0036719084
-
Influence of neuromelanin on oxidative pathways within the human substantia nigra
-
Double KL, Ben-Shachar D, Youdim MB, Zecca L, Riederer P, Gerlach M (2002) Influence of neuromelanin on oxidative pathways within the human substantia nigra. Neurotoxicol Teratol 24: 621-628
-
(2002)
Neurotoxicol Teratol
, vol.24
, pp. 621-628
-
-
Double, K.L.1
Ben-Shachar, D.2
Youdim, M.B.3
Zecca, L.4
Riederer, P.5
Gerlach, M.6
-
38
-
-
0034661820
-
Neuropathology of synuclein aggregates. New insights into mechanism of neurodegenerative diseases
-
Duda JE, Lee VMY, Trojanowski JQ (2000) Neuropathology of synuclein aggregates. New insights into mechanism of neurodegenerative diseases. J Neurosci Res 61: 121-127
-
(2000)
J Neurosci Res
, vol.61
, pp. 121-127
-
-
Duda, J.E.1
Lee, V.M.Y.2
Trojanowski, J.Q.3
-
39
-
-
0037357190
-
Iron-induced oxidative stress modify tau phosphorylation patterns in hippocampal cell cultures
-
Egana JT, Zambrano C, Nunez MT, Gonzalez-Billault C, Maccioni RB (2003) Iron-induced oxidative stress modify tau phosphorylation patterns in hippocampal cell cultures. Biometals 16: 215-223
-
(2003)
Biometals
, vol.16
, pp. 215-223
-
-
Egana, J.T.1
Zambrano, C.2
Nunez, M.T.3
Gonzalez-Billault, C.4
Maccioni, R.B.5
-
40
-
-
0036014117
-
Mutant and wild-type α-synuclein interact with mitochondrial cytochrome C oxidase
-
Elkon H, Don J, Melamed E, Ziv I, Shirvan A, Offen D (2002) Mutant and wild-type α-synuclein interact with mitochondrial cytochrome C oxidase. J Mol Neurosci 18: 229-238
-
(2002)
J Mol Neurosci
, vol.18
, pp. 229-238
-
-
Elkon, H.1
Don, J.2
Melamed, E.3
Ziv, I.4
Shirvan, A.5
Offen, D.6
-
41
-
-
0034704752
-
A Drosophila model of Parkinson's disease
-
Feany MB, Bender WW (2000) A Drosophila model of Parkinson's disease. Nature 404: 394-398
-
(2000)
Nature
, vol.404
, pp. 394-398
-
-
Feany, M.B.1
Bender, W.W.2
-
42
-
-
0035827364
-
PABMB Lecture. Protein dynamics, folding and misfolding: From basic physical chemistry to human conformational diseases
-
Ferreira ST, De Felice FG (2001) PABMB Lecture. Protein dynamics, folding and misfolding: from basic physical chemistry to human conformational diseases. FEBS Lett 498: 129-134
-
(2001)
FEBS Lett
, vol.498
, pp. 129-134
-
-
Ferreira, S.T.1
De Felice, F.G.2
-
43
-
-
0035668350
-
Active, phosphorylation-dependent mitogen-activated protein kinase (MAPK/ ERK), stress-activated protein kinase/c-Jun N-terminal kinase (SAPK/JNK), and p38 kinase expression in Parkinson's disease and Dementia with Lewy bodies
-
Ferrer I, Blanco R, Carmona M, Puig B, Barrachina M, Gomez C, Ambrosio S (2001) Active, phosphorylation-dependent mitogen-activated protein kinase (MAPK/ ERK), stress-activated protein kinase/c-Jun N-terminal kinase (SAPK/JNK), and p38 kinase expression in Parkinson's disease and Dementia with Lewy bodies. J Neural Transm 108: 1383-1396
-
(2001)
J Neural Transm
, vol.108
, pp. 1383-1396
-
-
Ferrer, I.1
Blanco, R.2
Carmona, M.3
Puig, B.4
Barrachina, M.5
Gomez, C.6
Ambrosio, S.7
-
44
-
-
0033021002
-
Neuroinflammatory processes are important in neurodegenerative diseases: An hypothesis to explain the increased formation of reactive oxygen and nitrogen species as major factors involved in neurodegenerative disease development
-
Floyd RA (1999) Neuroinflammatory processes are important in neurodegenerative diseases: an hypothesis to explain the increased formation of reactive oxygen and nitrogen species as major factors involved in neurodegenerative disease development. Free Radic Biol Med 26: 1346-1355
-
(1999)
Free Radic Biol Med
, vol.26
, pp. 1346-1355
-
-
Floyd, R.A.1
-
45
-
-
0036752519
-
Protein misfolding in Alzheimer's and Parkinson's disease: Genetics and molecular mechanisms
-
Forloni G, Terreni L, Bertani I, Fogliarino S, Invernizzi R, Assini A, Ribizzi G, Negro A, Calabrese E, Volonte MA, Mariani C, Franceschi M, Tabaton M, Bertoli A (2002) Protein misfolding in Alzheimer's and Parkinson's disease: genetics and molecular mechanisms. Neurobiol Aging 23: 957-976
-
(2002)
Neurobiol Aging
, vol.23
, pp. 957-976
-
-
Forloni, G.1
Terreni, L.2
Bertani, I.3
Fogliarino, S.4
Invernizzi, R.5
Assini, A.6
Ribizzi, G.7
Negro, A.8
Calabrese, E.9
Volonte, M.A.10
Mariani, C.11
Franceschi, M.12
Tabaton, M.13
Bertoli, A.14
-
46
-
-
0036174010
-
α-Synuclein is phosphorylated in synucleinopathy lesions
-
Fujiwara H, Hasegawa M, Dohmae N, Kawashima A, Masliah E, Goldberg MS, Shen J, Takio K, Iwatsubo T (2002) α-Synuclein is phosphorylated in synucleinopathy lesions. Nat Cell Biol 4: 160-164
-
(2002)
Nat Cell Biol
, vol.4
, pp. 160-164
-
-
Fujiwara, H.1
Hasegawa, M.2
Dohmae, N.3
Kawashima, A.4
Masliah, E.5
Goldberg, M.S.6
Shen, J.7
Takio, K.8
Iwatsubo, T.9
-
47
-
-
0036260836
-
Brain proteasomal function in sporadic Parkinson's disease and related disorders
-
Furukawa Y, Vigouroux S, Wong H, Guttman M, Rajput AH, Ang L, Briand M, Kish SJ, Briand Y (2002) Brain proteasomal function in sporadic Parkinson's disease and related disorders. Ann Neurol 51: 779-782
-
(2002)
Ann Neurol
, vol.51
, pp. 779-782
-
-
Furukawa, Y.1
Vigouroux, S.2
Wong, H.3
Guttman, M.4
Rajput, A.H.5
Ang, L.6
Briand, M.7
Kish, S.J.8
Briand, Y.9
-
48
-
-
0033669319
-
In situ and in vitro study of colocalization and segregation of α-synuclein, ubiquitin, and lipids in Lewy bodies
-
Gai WP, Yuan HX, Li XQ, Power JT, Blumbergs PC, Jensen PH (2000) In situ and in vitro study of colocalization and segregation of α-synuclein, ubiquitin, and lipids in Lewy bodies. Exp Neurol 166: 324-333
-
(2000)
Exp Neurol
, vol.166
, pp. 324-333
-
-
Gai, W.P.1
Yuan, H.X.2
Li, X.Q.3
Power, J.T.4
Blumbergs, P.C.5
Jensen, P.H.6
-
49
-
-
0035109738
-
Synucleinopathies: Clinical and pathological implications
-
Galvin JE, Lee VM, Trojanowski JQ (2001) Synucleinopathies: clinical and pathological implications. Arch Neurol 58: 186-190
-
(2001)
Arch Neurol
, vol.58
, pp. 186-190
-
-
Galvin, J.E.1
Lee, V.M.2
Trojanowski, J.Q.3
-
50
-
-
0036316772
-
Microglial activation-mediated delayed and progressive degeneration of rat nigral dopaminergic neurons: Relevance to Parkinson's disease
-
Gao HM, Jiang J, Wilson B, Zhang W, Hong JS, Liu B (2002) Microglial activation-mediated delayed and progressive degeneration of rat nigral dopaminergic neurons: relevance to Parkinson's disease. J Neurochem 81: 1285-1297
-
(2002)
J Neurochem
, vol.81
, pp. 1285-1297
-
-
Gao, H.M.1
Jiang, J.2
Wilson, B.3
Zhang, W.4
Hong, J.S.5
Liu, B.6
-
51
-
-
0033792866
-
Overexpression of neutrophil neuronal nitric oxide synthase in Parkinson's disease
-
Gatto EM, Riobo NA, Carreras MC, Chernavsky A, Rubio A, Satz ML, Poderoso JJ (2000) Overexpression of neutrophil neuronal nitric oxide synthase in Parkinson's disease. Nitric Oxide 4: 534-539
-
(2000)
Nitric Oxide
, vol.4
, pp. 534-539
-
-
Gatto, E.M.1
Riobo, N.A.2
Carreras, M.C.3
Chernavsky, A.4
Rubio, A.5
Satz, M.L.6
Poderoso, J.J.7
-
52
-
-
0034602442
-
Oxidative damage linked to neurodegeneration by selective α-synuclein nitration in synucleinopathy lesions
-
Giasson BI, Duda JE, Murray IV, Chen Q, Souza JM, Hurtig HI, Ischiropoulos H, Trojanowski JQ, Lee VM (2000) Oxidative damage linked to neurodegeneration by selective α-synuclein nitration in synucleinopathy lesions. Science 290: 985-989
-
(2000)
Science
, vol.290
, pp. 985-989
-
-
Giasson, B.I.1
Duda, J.E.2
Murray, I.V.3
Chen, Q.4
Souza, J.M.5
Hurtig, H.I.6
Ischiropoulos, H.7
Trojanowski, J.Q.8
Lee, V.M.9
-
53
-
-
0037096193
-
The relationship between oxidative/nitrative stress and pathological inclusions in Alzheimer's and Parkinson's diseases
-
Giasson BI, Ischiropoulos H, Lee VM, Trojanowski JQ (2002) The relationship between oxidative/nitrative stress and pathological inclusions in Alzheimer's and Parkinson's diseases. Free Radic Biol Med 32: 1264-1275
-
(2002)
Free Radic Biol Med
, vol.32
, pp. 1264-1275
-
-
Giasson, B.I.1
Ischiropoulos, H.2
Lee, V.M.3
Trojanowski, J.Q.4
-
55
-
-
84855224829
-
Parkinson's disease, dementia with Lewy bodies, and multiple system atrophy as α-synucleinopathies
-
Mouradian MM (ed) Humana Press Inc., Totawa
-
Goedert M, Jakes R, Crowther RA, Spillantini MG (2001) Parkinson's disease, dementia with Lewy bodies, and multiple system atrophy as α-synucleinopathies. In: Mouradian MM (ed) Parkinson's disease: methods and protocols. Humana Press Inc., Totawa, pp 33-59
-
(2001)
Parkinson's Disease: Methods and Protocols
, pp. 33-59
-
-
Goedert, M.1
Jakes, R.2
Crowther, R.A.3
Spillantini, M.G.4
-
56
-
-
0037157540
-
Neurodegeneration in the age of molecular biology
-
Golbe LI (2002) Neurodegeneration in the age of molecular biology. BMJ 324: 1467-1468
-
(2002)
BMJ
, vol.324
, pp. 1467-1468
-
-
Golbe, L.I.1
-
57
-
-
0033771793
-
Is there a cause-and-effect relationship between α-synuclein fibrillization and Parkinson's disease?
-
Goldberg MS, Lansbury PT Jr (2000) Is there a cause-and-effect relationship between α-synuclein fibrillization and Parkinson's disease? Nat Cell Biol 2: E115-E119
-
(2000)
Nat Cell Biol
, vol.2
-
-
Goldberg, M.S.1
Lansbury Jr., P.T.2
-
58
-
-
0036943010
-
Patterns of protein nitration in dementia with Lewy bodies and striatonigral degeneration
-
Gómez-Tortosa E, Gonzalo I, Newell K, Yébenes JG, Vonsattel JP, Hyman BT (2002) Patterns of protein nitration in dementia with Lewy bodies and striatonigral degeneration. Acta Neuropathol 103: 495-500
-
(2002)
Acta Neuropathol
, vol.103
, pp. 495-500
-
-
Gómez-Tortosa, E.1
Gonzalo, I.2
Newell, K.3
Yébenes, J.G.4
Vonsattel, J.P.5
Hyman, B.T.6
-
59
-
-
0035943436
-
Formation of neurofibrillary tangles in P3011 tau transgenic mice induced by Aβ 42 fibrils
-
Götz J, Chen F, van Dorpe J, Nitsch RM (2001) Formation of neurofibrillary tangles in P3011 tau transgenic mice induced by Aβ 42 fibrils. Science 293: 1491-1495
-
(2001)
Science
, vol.293
, pp. 1491-1495
-
-
Götz, J.1
Chen, F.2
Van Dorpe, J.3
Nitsch, R.M.4
-
61
-
-
0031983986
-
Glial-neuronal interactions in Alzheimer's disease: The potential role of a "cytokine cycle" in disease progression
-
Griffin WS, Sheng JG, Royston MC, Gentleman SM, McKenzie JE, Graham DI, Roberts GW, Mrak RE (1998) Glial-neuronal interactions in Alzheimer's disease: the potential role of a "cytokine cycle" in disease progression. Brain Pathol 8: 65-72
-
(1998)
Brain Pathol
, vol.8
, pp. 65-72
-
-
Griffin, W.S.1
Sheng, J.G.2
Royston, M.C.3
Gentleman, S.M.4
McKenzie, J.E.5
Graham, D.I.6
Roberts, G.W.7
Mrak, R.E.8
-
62
-
-
17644438751
-
Association of early-onset Alzheimer's disease with an interleukin-1alpha gene polymorphism
-
Grimaldi LM, Casadei VM, Ferri C, Veglia F, Licastro F, Annoni G, Biunno I, De Bellis G, Sorbi S, Mariani C, Canal N, Griffin WS, Franceschi M (2000) Association of early-onset Alzheimer's disease with an interleukin-1alpha gene polymorphism. Ann Neurol 47: 361-365
-
(2000)
Ann Neurol
, vol.47
, pp. 361-365
-
-
Grimaldi, L.M.1
Casadei, V.M.2
Ferri, C.3
Veglia, F.4
Licastro, F.5
Annoni, G.6
Biunno, I.7
De Bellis, G.8
Sorbi, S.9
Mariani, C.10
Canal, N.11
Griffin, W.S.12
Franceschi, M.13
-
63
-
-
0036298182
-
Mitochondrial DNA deletions/rearrangements in parkinson disease and related neurodegenerative disorders
-
Gu G, Reyes PE, Golden GT, Woltjer RL, Hulette C, Montine TJ, Zhang J (2002) Mitochondrial DNA deletions/rearrangements in parkinson disease and related neurodegenerative disorders. J Neuropathol Exp Neurol 61: 634-639
-
(2002)
J Neuropathol Exp Neurol
, vol.61
, pp. 634-639
-
-
Gu, G.1
Reyes, P.E.2
Golden, G.T.3
Woltjer, R.L.4
Hulette, C.5
Montine, T.J.6
Zhang, J.7
-
64
-
-
0033616796
-
Neurotrophic factors [activity-dependent neurotrophic factor (ADNF) and basic fibroblast growth factor (bFGF)] interrupt excitotoxic neurodegenerative cascades promoted by a PS1 mutation
-
Guo Q, Sebastian L, Sopher BL, Miller MW, Glazner GW, Ware CB, Martin GM, Mattson MP (1999) Neurotrophic factors [activity-dependent neurotrophic factor (ADNF) and basic fibroblast growth factor (bFGF)] interrupt excitotoxic neurodegenerative cascades promoted by a PS1 mutation. Proc Natl Acad Sci USA 96: 4125-4130
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 4125-4130
-
-
Guo, Q.1
Sebastian, L.2
Sopher, B.L.3
Miller, M.W.4
Glazner, G.W.5
Ware, C.B.6
Martin, G.M.7
Mattson, M.P.8
-
65
-
-
0034796353
-
Role of free radicals in the neurodegenerative diseases: Therapeutic implications for antioxidant treatment
-
Halliwell B (2001) Role of free radicals in the neurodegenerative diseases: therapeutic implications for antioxidant treatment. Drugs Aging 18: 685-716
-
(2001)
Drugs Aging
, vol.18
, pp. 685-716
-
-
Halliwell, B.1
-
66
-
-
0142234211
-
Neurobiology of disorders with Lewy bodies
-
Hof RR, Mobbs LCK (eds) Academic Press, San Diego
-
Hansen L, Masliah E (2001) Neurobiology of disorders with Lewy bodies. In: Hof RR, Mobbs LCK (eds) Functional neurobiology of aging. Academic Press, San Diego, pp 173-182
-
(2001)
Functional Neurobiology of Aging
, pp. 173-182
-
-
Hansen, L.1
Masliah, E.2
-
67
-
-
0036311251
-
Increased expression and redistribution of the antiapoptotic molecule Bcl-xL in Parkinson's disease
-
Hartmann A, Mouatt-Prigent A, Vila M, Abbas N, Perier C, Faucheux BA, Vyas S, Hirsch EC (2002) Increased expression and redistribution of the antiapoptotic molecule Bcl-xL in Parkinson's disease. Neurobiol Dis 10: 28-32
-
(2002)
Neurobiol Dis
, vol.10
, pp. 28-32
-
-
Hartmann, A.1
Mouatt-Prigent, A.2
Vila, M.3
Abbas, N.4
Perier, C.5
Faucheux, B.A.6
Vyas, S.7
Hirsch, E.C.8
-
68
-
-
0037472654
-
Ubiquitin binding proteins protect ubiquitin conjugates from disassembly
-
Hartmann-Petersen R, Hendil KB, Gordon C (2003) Ubiquitin binding proteins protect ubiquitin conjugates from disassembly. FEBS Lett 535: 77-81
-
(2003)
FEBS Lett
, vol.535
, pp. 77-81
-
-
Hartmann-Petersen, R.1
Hendil, K.B.2
Gordon, C.3
-
69
-
-
2242472974
-
Phosphorylated α-synuclein is ubiquitinated in α- synucleinopathy lesions
-
Hasegawa M, Fujiwara H, Nonaka T, Wakabayashi K, Takahashi H, Lee VM, Trojanowski JQ, Mann D, Iwatsubo T (2002) Phosphorylated α-synuclein is ubiquitinated in α-synucleinopathy lesions. J Biol Chem 277: 49071-49076
-
(2002)
J Biol Chem
, vol.277
, pp. 49071-49076
-
-
Hasegawa, M.1
Fujiwara, H.2
Nonaka, T.3
Wakabayashi, K.4
Takahashi, H.5
Lee, V.M.6
Trojanowski, J.Q.7
Mann, D.8
Iwatsubo, T.9
-
70
-
-
0032888789
-
α-Synuclein in Lewy body disease and Alzheimer's disease
-
Hashimoto M, Masliah E (1999) α-Synuclein in Lewy body disease and Alzheimer's disease. Brain Pathol 9: 707-720
-
(1999)
Brain Pathol
, vol.9
, pp. 707-720
-
-
Hashimoto, M.1
Masliah, E.2
-
71
-
-
1542537128
-
Postencephalitic parkinsonism
-
Dickson DW et al (eds) ISN Neuropathology Press, Los Angeles (in press)
-
Henry JM, Jellinger KA (2003) Postencephalitic parkinsonism. In: Dickson DW et al (eds) Neurodegeneration and dementias. ISN Neuropathology Press, Los Angeles (in press)
-
(2003)
Neurodegeneration and Dementias
-
-
Henry, J.M.1
Jellinger, K.A.2
-
72
-
-
0033178889
-
Regional distribution of cyclooxygenase-2 in the hippocampal formation in Alzheimer's disease
-
Ho L, Pieroni C, Winger D, Purohit DP, Aisen PS, Pasinetti GM (1999) Regional distribution of cyclooxygenase-2 in the hippocampal formation in Alzheimer's disease. J Neurosci Res 57: 295-303
-
(1999)
J Neurosci Res
, vol.57
, pp. 295-303
-
-
Ho, L.1
Pieroni, C.2
Winger, D.3
Purohit, D.P.4
Aisen, P.S.5
Pasinetti, G.M.6
-
73
-
-
0035997016
-
Protein aggregation in Huntington's disease
-
Hoffner G, Djian P (2002) Protein aggregation in Huntington's disease. Biochimie 84: 273-278
-
(2002)
Biochimie
, vol.84
, pp. 273-278
-
-
Hoffner, G.1
Djian, P.2
-
74
-
-
0033890821
-
α-Synuclein promotes mitochondrial deficit and oxidative stress
-
Hsu LJ, Sagara Y, Arroyo A, Rockenstein E, Sisk A, Mallory M, Wong J, Takenoucnik T, Hashimoto M, Masliah E (2000) α-Synuclein promotes mitochondrial deficit and oxidative stress. Am J Pathol 157: 401-440
-
(2000)
Am J Pathol
, vol.157
, pp. 401-440
-
-
Hsu, L.J.1
Sagara, Y.2
Arroyo, A.3
Rockenstein, E.4
Sisk, A.5
Mallory, M.6
Wong, J.7
Takenoucnik, T.8
Hashimoto, M.9
Masliah, E.10
-
75
-
-
0034714346
-
Gluthathione depletion in PC12 results in selective inhibitation of mitochondrial complex I activity: Implications for Parkinson's disease
-
Iha N, Jurma OP, Lalli G, Liu Y, Pettus EH, Greenamyre JT, Liu RM, Forman HJ, Andersen JK (2000) Gluthathione depletion in PC12 results in selective inhibitation of mitochondrial complex I activity: implications for Parkinson's disease. J Biol Chem 275: 26096-26101
-
(2000)
J Biol Chem
, vol.275
, pp. 26096-26101
-
-
Iha, N.1
Jurma, O.P.2
Lalli, G.3
Liu, Y.4
Pettus, E.H.5
Greenamyre, J.T.6
Liu, R.M.7
Forman, H.J.8
Andersen, J.K.9
-
76
-
-
1542432294
-
Dementia with Lewy bodies
-
Dickson DW et al (eds) ISN Neuropathology Press, Los Angeles (in press)
-
Ince PG, McKeith IG (2003) Dementia with Lewy bodies. In: Dickson DW et al (eds) Neurodegeneration and dementias. ISN Neuropathology Press, Los Angeles (in press)
-
(2003)
Neurodegeneration and Dementias
-
-
Ince, P.G.1
McKeith, I.G.2
-
77
-
-
0035976959
-
α-Synuclein affects the MAPK pathway and accelerates cell death
-
Iwata A, Maruyama M, Kanazawa I, Nukina N (2001) α-Synuclein affects the MAPK pathway and accelerates cell death. J Biol Chem 276: 45320-45329
-
(2001)
J Biol Chem
, vol.276
, pp. 45320-45329
-
-
Iwata, A.1
Maruyama, M.2
Kanazawa, I.3
Nukina, N.4
-
78
-
-
85046909683
-
Cell death mechanisms in neurodegeneration
-
Jellinger KA (2001) Cell death mechanisms in neurodegeneration. J Cell Mol Med 5: 1-17
-
(2001)
J Cell Mol Med
, vol.5
, pp. 1-17
-
-
Jellinger, K.A.1
-
79
-
-
1542747255
-
Apoptosis vs. non-apoptotic mechanisms in neurodegeneration
-
Wood PL (ed) Humana Press, Totowa
-
Jellinger KA (2003a) Apoptosis vs. non-apoptotic mechanisms in neurodegeneration. In: Wood PL (ed) Neuroinflammation, 2nd ed. Humana Press, Totowa, pp 29-88
-
(2003)
Neuroinflammation, 2nd Ed.
, pp. 29-88
-
-
Jellinger, K.A.1
-
80
-
-
1542432300
-
Experimental models of synucleinopathies
-
Dickson DW et al (eds) ISN Neuropathology Press, Los Angeles (in press)
-
Jellinger KA (2003b) Experimental models of synucleinopathies. In: Dickson DW et al (eds) Neurodegeneration and dementias. ISN Neuropathology Press, Los Angeles (in press)
-
(2003)
Neurodegeneration and Dementias
-
-
Jellinger, K.A.1
-
81
-
-
1542641975
-
Neuroaxonal dystrophies
-
Dickson DW et al (eds) ISN Neuropathology Press, Los Angeles (in press)
-
Jellinger KA, Duda J (2003) Neuroaxonal dystrophies. In: Dickson DW et al (eds) Neurodegeneration and dementias. ISN Neuropathology Press, Los Angeles (in press)
-
(2003)
Neurodegeneration and Dementias
-
-
Jellinger, K.A.1
Duda, J.2
-
82
-
-
0042502639
-
Parkinson disease
-
Dickson DW et al (eds) ISN Neuropathology Press, Los Angeles (in press)
-
Jellinger KA, Mizuno Y (2003) Parkinson disease. In: Dickson DW et al (eds) Neurodegeneration and dementias. ISN Neuropathology Press, Los Angeles (in press)
-
(2003)
Neurodegeneration and Dementias
-
-
Jellinger, K.A.1
Mizuno, Y.2
-
83
-
-
0033940437
-
Late-onset neujrodegenerative diseases - The role of protein insolubility
-
Johnson WG (2001) Late-onset neujrodegenerative diseases - the role of protein insolubility. J Anat 196: 609-616
-
(2001)
J Anat
, vol.196
, pp. 609-616
-
-
Johnson, W.G.1
-
84
-
-
0034604341
-
Regulation of transcription by ubiquitination without proteolysis: Cdc34/SCF(Met30)-mediated inactivation of the transcription factor Met4
-
Kaiser P, Flick K, Wittenberg C, Reed SI (2000) Regulation of transcription by ubiquitination without proteolysis: Cdc34/SCF(Met30)-mediated inactivation of the transcription factor Met4. Cell 102: 303-314
-
(2000)
Cell
, vol.102
, pp. 303-314
-
-
Kaiser, P.1
Flick, K.2
Wittenberg, C.3
Reed, S.I.4
-
85
-
-
0033949936
-
Gallyas-positive argyrophilic and ubiquitinated filamentous inclusions in rapidly progressive motor neuron disease: Immunohistochemical and electron microscopic studies
-
Katayama S, Watanabe C, Kohriyama T, Yamamura Y, Mao JJ, Ohishi H, Nishisaka T, Inai K, Tanaka E, Nakamura S (2000) Gallyas-positive argyrophilic and ubiquitinated filamentous inclusions in rapidly progressive motor neuron disease: immunohistochemical and electron microscopic studies. Acta Neuropathol 100: 221-227
-
(2000)
Acta Neuropathol
, vol.100
, pp. 221-227
-
-
Katayama, S.1
Watanabe, C.2
Kohriyama, T.3
Yamamura, Y.4
Mao, J.J.5
Ohishi, H.6
Nishisaka, T.7
Inai, K.8
Tanaka, E.9
Nakamura, S.10
-
86
-
-
0345714885
-
Iron misregulation in the brain: A primary cause of neurodegenerative disorders
-
Ke Y, Qian ZM (2003) Iron misregulation in the brain: a primary cause of neurodegenerative disorders. Lancet Neurol 2: 246-252
-
(2003)
Lancet Neurol
, vol.2
, pp. 246-252
-
-
Ke, Y.1
Qian, Z.M.2
-
87
-
-
0036197296
-
Systemic increase of oxidative nucleic acid damage in Parkinson's disease and multiple system atrophy
-
Kikuchi A, Takeda A, Onodera H, Kimpara T, Hisanaga K, Sato N, Nunomura A, Castellani RJ, Perry G, Smith MA, Itoyama Y (2002) Systemic increase of oxidative nucleic acid damage in Parkinson's disease and multiple system atrophy. Neurobiol Dis 9: 244-248
-
(2002)
Neurobiol Dis
, vol.9
, pp. 244-248
-
-
Kikuchi, A.1
Takeda, A.2
Onodera, H.3
Kimpara, T.4
Hisanaga, K.5
Sato, N.6
Nunomura, A.7
Castellani, R.J.8
Perry, G.9
Smith, M.A.10
Itoyama, Y.11
-
88
-
-
0033743320
-
Protein disulfide isomerase in Alzheimer disease
-
Kim HT, Russell RL, Raina AK, Harris PL, Siedlak SL, Zhu X, Petersen RB, Shimohama S, Smith MA, Perry G (2000) Protein disulfide isomerase in Alzheimer disease. Antioxid Redox Signal 2: 485-489
-
(2000)
Antioxid Redox Signal
, vol.2
, pp. 485-489
-
-
Kim, H.T.1
Russell, R.L.2
Raina, A.K.3
Harris, P.L.4
Siedlak, S.L.5
Zhu, X.6
Petersen, R.B.7
Shimohama, S.8
Smith, M.A.9
Perry, G.10
-
89
-
-
0036661699
-
The ceruloplasmin and hydrogen peroxide system induces alpha-synuclein aggregation in vitro
-
Kim KS, Choi SY, Kwon HY, Won MH, Kang TC, Kang JH (2002) The ceruloplasmin and hydrogen peroxide system induces alpha-synuclein aggregation in vitro. Biochimie 84: 625-631
-
(2002)
Biochimie
, vol.84
, pp. 625-631
-
-
Kim, K.S.1
Choi, S.Y.2
Kwon, H.Y.3
Won, M.H.4
Kang, T.C.5
Kang, J.H.6
-
90
-
-
0037127261
-
Proteolytic processing of familial British dementia-associated BRI variants: Evidence for enhanced intracellular accumulation of amyloidogenic peptides
-
Kim SH, Creemers JW, Chu S, Thinakaran G, Sisodia SS (2002) Proteolytic processing of familial British dementia-associated BRI variants: evidence for enhanced intracellular accumulation of amyloidogenic peptides. J Biol Chem 277: 1872-1877
-
(2002)
J Biol Chem
, vol.277
, pp. 1872-1877
-
-
Kim, S.H.1
Creemers, J.W.2
Chu, S.3
Thinakaran, G.4
Sisodia, S.S.5
-
91
-
-
0032499264
-
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
-
Kitada T, Asakawa S, Hattori N, Matsumine H, Yamamura Y, Minoshima S, Yokochi M, Mizuno Y, Shimizu N (1998) Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism. Nature 392: 605-608
-
(1998)
Nature
, vol.392
, pp. 605-608
-
-
Kitada, T.1
Asakawa, S.2
Hattori, N.3
Matsumine, H.4
Yamamura, Y.5
Minoshima, S.6
Yokochi, M.7
Mizuno, Y.8
Shimizu, N.9
-
92
-
-
0032475941
-
Ataxin-1 nuclear localization and aggregation: Role in polyglutamine-induced disease in SCA1 transgenic mice
-
Klement IA, Skinner PJ, Kaytor MD, Yi H, Hersch SM, Clark HB, Zoghbi HY, Orr HT (1998) Ataxin-1 nuclear localization and aggregation: role in polyglutamine-induced disease in SCA1 transgenic mice. Cell 95: 41-53
-
(1998)
Cell
, vol.95
, pp. 41-53
-
-
Klement, I.A.1
Skinner, P.J.2
Kaytor, M.D.3
Yi, H.4
Hersch, S.M.5
Clark, H.B.6
Zoghbi, H.Y.7
Orr, H.T.8
-
93
-
-
0034578389
-
Aggresomes, inclusion bodies and protein aggregation
-
Kopito RR (2000) Aggresomes, inclusion bodies and protein aggregation. Trends Cell Biol 10: 524-350
-
(2000)
Trends Cell Biol
, vol.10
, pp. 524-1350
-
-
Kopito, R.R.1
-
94
-
-
0037454949
-
Nucleus-specific alteration of raphe neurons in human neurodegenerative disorders
-
Kovacs GG, Kloppel S, Fischer I, Dorner S, Lindeck-Pozza E, Birner P, Botefur IC, Pilz P, Volk B, Budka H (2003) Nucleus-specific alteration of raphe neurons in human neurodegenerative disorders. Neuroreport 14: 73-76
-
(2003)
Neuroreport
, vol.14
, pp. 73-76
-
-
Kovacs, G.G.1
Kloppel, S.2
Fischer, I.3
Dorner, S.4
Lindeck-Pozza, E.5
Birner, P.6
Botefur, I.C.7
Pilz, P.8
Volk, B.9
Budka, H.10
-
95
-
-
0037025256
-
Mitochondria, Ca(2+) and neurodegenerative disease
-
Krieger C, Duchen MR (2002) Mitochondria, Ca(2+) and neurodegenerative disease. Eur J Pharmacol 447: 177-188
-
(2002)
Eur J Pharmacol
, vol.447
, pp. 177-188
-
-
Krieger, C.1
Duchen, M.R.2
-
96
-
-
0035230537
-
Alzheimer's disease: Its diagnosis and pathogenesis
-
Kril JJ, Halliday GM (2001) Alzheimer's disease: its diagnosis and pathogenesis. Int Rev Neurobiol 48: 167-217
-
(2001)
Int Rev Neurobiol
, vol.48
, pp. 167-217
-
-
Kril, J.J.1
Halliday, G.M.2
-
97
-
-
1542432294
-
Dementia with Lewy bodies
-
Dickson DW et al (eds) ISN Neuropathology Press, Los Angeles (in press)
-
Lantos PL, Quinn N (2003) Dementia with Lewy bodies. In: Dickson DW et al (eds) Neurodegeneration and dementias. ISN Neuropathology Press, Los Angeles (in press)
-
(2003)
Neurodegeneration and Dementias
-
-
Lantos, P.L.1
Quinn, N.2
-
98
-
-
0028833215
-
Cell death in Alzheimer's disease evaluated by DNA fragmentation in situ
-
Lassmann H, Bancher C, Breitschopf H, Wegiel J, Bobinski M, Jellinger K, Wisniewski HM (1995) Cell death in Alzheimer's disease evaluated by DNA fragmentation in situ. Acta Neuropathol 89: 35-41
-
(1995)
Acta Neuropathol
, vol.89
, pp. 35-41
-
-
Lassmann, H.1
Bancher, C.2
Breitschopf, H.3
Wegiel, J.4
Bobinski, M.5
Jellinger, K.6
Wisniewski, H.M.7
-
99
-
-
0034682414
-
Neurotoxicity induces cleavage of p35 to p25 by calpain
-
Lee MS, Kwon YT, Li M, Peng J, Friedlander RM, Tsai LH (2000) Neurotoxicity induces cleavage of p35 to p25 by calpain. Nature 405: 360-364
-
(2000)
Nature
, vol.405
, pp. 360-364
-
-
Lee, M.S.1
Kwon, Y.T.2
Li, M.3
Peng, J.4
Friedlander, R.M.5
Tsai, L.H.6
-
101
-
-
0042595320
-
Cell death mechanisms and the role of iron in neurodegeneration
-
Segura-Aquilar J (ed) FP Graham Publishing, Johnson City
-
Linert W, Jellinger KA (2001) Cell death mechanisms and the role of iron in neurodegeneration. In: Segura-Aquilar J (ed) Mechanisms of degeneration and protection of the dopaminergic system. FP Graham Publishing, Johnson City, pp 21-65
-
(2001)
Mechanisms of Degeneration and Protection of the Dopaminergic System
, pp. 21-65
-
-
Linert, W.1
Jellinger, K.A.2
-
102
-
-
1542537129
-
Lewy bodies in conditions other than disorders of α-synuclein
-
Dickson DW et al (eds) ISN Neuropathology Press, Los Angeles (in press)
-
Lippa CF (2003) Lewy bodies in conditions other than disorders of α-synuclein. In: Dickson DW et al (eds) Neurodegeneration and dementias. ISN Neuropathology Press, Los Angeles (in press)
-
(2003)
Neurodegeneration and Dementias
-
-
Lippa, C.F.1
-
103
-
-
0036797552
-
Impaired dopamine storage resulting from α-synuclein mutations may contribute to the pathogenesis of Parkinson's disease
-
Lotharius J, Brundin P (2002) Impaired dopamine storage resulting from α-synuclein mutations may contribute to the pathogenesis of Parkinson's disease. Hum Mol Genet 11: 2395-2407
-
(2002)
Hum Mol Genet
, vol.11
, pp. 2395-2407
-
-
Lotharius, J.1
Brundin, P.2
-
104
-
-
0036157895
-
Protein aggregates and dementia: Is there a common toxicity?
-
Lovestone S, McLoughlin DM (2002) Protein aggregates and dementia: is there a common toxicity? J Neurol Neurosurg Psychiatry 72: 152-161
-
(2002)
J Neurol Neurosurg Psychiatry
, vol.72
, pp. 152-161
-
-
Lovestone, S.1
McLoughlin, D.M.2
-
105
-
-
0030937952
-
The phosphorylation of tau: A critical stage in neurodevelopment and neurodegenerative processes
-
Lovestone S, Reynolds CH (1997) The phosphorylation of tau: a critical stage in neurodevelopment and neurodegenerative processes. Neuroscience 78: 309-324
-
(1997)
Neuroscience
, vol.78
, pp. 309-324
-
-
Lovestone, S.1
Reynolds, C.H.2
-
106
-
-
0036386073
-
Pathological peptide folding in Alzheimer disease and other conformational disorders
-
Mager P, Penke B, Walter R, Harkany T, Hartig W (2002) Pathological peptide folding in Alzheimer disease and other conformational disorders. Curr Med Chem 9: 1763-1780
-
(2002)
Curr Med Chem
, vol.9
, pp. 1763-1780
-
-
Mager, P.1
Penke, B.2
Walter, R.3
Harkany, T.4
Hartig, W.5
-
107
-
-
0037127197
-
The herbicide paraquat causes up-regulation and aggregation of α-synuclein in mice: Paraquat and α-synuclein
-
Manning-Bog AB, McCormack AL, Li J, Uversky VN, Fink AL, Di Monte DA (2002) The herbicide paraquat causes up-regulation and aggregation of α-synuclein in mice: paraquat and α-synuclein. J Biol Chem 277: 1641-1644
-
(2002)
J Biol Chem
, vol.277
, pp. 1641-1644
-
-
Manning-Bog, A.B.1
McCormack, A.L.2
Li, J.3
Uversky, V.N.4
Fink, A.L.5
Di Monte, D.A.6
-
108
-
-
0002469416
-
Oxidative alterations in neurodegenerative diseases
-
Mattson MP (ed) Humana Press, Totowa
-
Markesbery WR, Montine DJ, Lovell MA (2001) Oxidative alterations in neurodegenerative diseases, In: Mattson MP (ed) Pathogenesis of neurodegenerative disorders. Humana Press, Totowa, pp 21-51
-
(2001)
Pathogenesis of Neurodegenerative Disorders
, pp. 21-51
-
-
Markesbery, W.R.1
Montine, D.J.2
Lovell, M.A.3
-
109
-
-
0035929569
-
New leads on the 'how' of Alzheimer's
-
Marx J (2001) New leads on the 'how' of Alzheimer's. Science 293: 2192-4219
-
(2001)
Science
, vol.293
, pp. 2192-4219
-
-
Marx, J.1
-
110
-
-
0035834076
-
β-amyloid peptides enhance α-synuclein accumulation and neuronal deficits in a transgenic mouse model linking Alzheimer's disease and Parkinson's disease
-
Masliah E, Rockenstein E, Veinbergs I, Sagara Y, Mallory M, Hashimoto M, Mucke L (2001) β-amyloid peptides enhance α-synuclein accumulation and neuronal deficits in a transgenic mouse model linking Alzheimer's disease and Parkinson's disease. Proc Natl Acad Sci USA 98: 12245-12250
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 12245-12250
-
-
Masliah, E.1
Rockenstein, E.2
Veinbergs, I.3
Sagara, Y.4
Mallory, M.5
Hashimoto, M.6
Mucke, L.7
-
111
-
-
1542432293
-
Inflammation, free radicals, glycation, metabolism and apoptosis, heavy metals
-
Hof RR, Mobbs LCK (eds) Academic Press, San Diego
-
Mattson MP (2001) Inflammation, free radicals, glycation, metabolism and apoptosis, heavy metals. In: Hof RR, Mobbs LCK (eds) Functional neurobiology of aging. Academic Press, San Diego, pp 349-371
-
(2001)
Functional Neurobiology of Aging
, pp. 349-371
-
-
Mattson, M.P.1
-
112
-
-
1542432296
-
Mechanisms of neuronal apoptosis and excitotoxicity
-
Mattson MP (ed) Humana Press, Totowa
-
Mattson MP (2001) Mechanisms of neuronal apoptosis and excitotoxicity. In: Mattson MP (ed) Pathogenesis of neurodegenerative disorders. Humana Press, Totowa, pp 1-20
-
(2001)
Pathogenesis of Neurodegenerative Disorders
, pp. 1-20
-
-
Mattson, M.P.1
-
113
-
-
0034084677
-
Autotoxicity and Alzheimer disease
-
McGeer PL, McGeer EG (2000) Autotoxicity and Alzheimer disease. Arch Neurol 57: 789-790
-
(2000)
Arch Neurol
, vol.57
, pp. 789-790
-
-
McGeer, P.L.1
McGeer, E.G.2
-
116
-
-
0038478782
-
Huntington's disease: New hope for therapeutics
-
McMurray CT (2001) Huntington's disease: new hope for therapeutics. TINS 24[Suppl]: S32-S37
-
(2001)
TINS
, vol.24
, Issue.SUPPL.
-
-
McMurray, C.T.1
-
117
-
-
0035430788
-
Failure of the ubiquitin-proteasome system in Parkinson's disease
-
McNaught KS, Olanow CW, Halliwell B, Isacson O, Jenner P (2001) Failure of the ubiquitin-proteasome system in Parkinson's disease. Nat Rev Neurosci 2: 589-594
-
(2001)
Nat Rev Neurosci
, vol.2
, pp. 589-594
-
-
McNaught, K.S.1
Olanow, C.W.2
Halliwell, B.3
Isacson, O.4
Jenner, P.5
-
118
-
-
0037227397
-
Altered proteasomal function in sporadic Parkinson's disease
-
McNaught KS, Belizaire R, Isacson O, Jenner P, Olanow CW (2003) Altered proteasomal function in sporadic Parkinson's disease. Exp Neurol 179: 38-46
-
(2003)
Exp Neurol
, vol.179
, pp. 38-46
-
-
McNaught, K.S.1
Belizaire, R.2
Isacson, O.3
Jenner, P.4
Olanow, C.W.5
-
119
-
-
0036456584
-
Aggresome-related biogenesis of Lewy bodies
-
McNaught KS, Shashidharan P, Perl DP, Jenner P, Olanow CW (2002) Aggresome-related biogenesis of Lewy bodies. Eur J Neurosci 16: 2136-2148
-
(2002)
Eur J Neurosci
, vol.16
, pp. 2136-2148
-
-
McNaught, K.S.1
Shashidharan, P.2
Perl, D.P.3
Jenner, P.4
Olanow, C.W.5
-
120
-
-
0035213152
-
Protein aggregation
-
Merlini G, Bellotti V, Andreola A, Palladini G, Obici L, Casarini S, Perfetti V (2001) Protein aggregation. Clin Chem Lab Med 39: 1065-1075
-
(2001)
Clin Chem Lab Med
, vol.39
, pp. 1065-1075
-
-
Merlini, G.1
Bellotti, V.2
Andreola, A.3
Palladini, G.4
Obici, L.5
Casarini, S.6
Perfetti, V.7
-
121
-
-
0037166267
-
Biochemical characterization of the core structure of α-synuclein filaments
-
Miake H, Mizusawa H, Iwatsubo T, Hasegawa M (2002) Biochemical characterization of the core structure of α-synuclein filaments. J Biol Chem 277: 19213-19219
-
(2002)
J Biol Chem
, vol.277
, pp. 19213-19219
-
-
Miake, H.1
Mizusawa, H.2
Iwatsubo, T.3
Hasegawa, M.4
-
122
-
-
0037215674
-
Neurological disease: UPS stops delivering!
-
Miller RJ, Wilson SM (2003) Neurological disease: UPS stops delivering! Trends Pharmacol Sci 24: 18-23
-
(2003)
Trends Pharmacol Sci
, vol.24
, pp. 18-23
-
-
Miller, R.J.1
Wilson, S.M.2
-
123
-
-
0036191771
-
Sequence analysis of tau in familial and sporadic progressive supranuclear palsy
-
Morris HR, Katzenschlager R, Janssen JC, Brown JM, Ozansoy M, Quinn N, Revesz T, Rossor MN, Daniel SE, Wood NW, Lees AJ (2002) Sequence analysis of tau in familial and sporadic progressive supranuclear palsy. J Neurol Neurosurg Psychiatry 72: 388-390
-
(2002)
J Neurol Neurosurg Psychiatry
, vol.72
, pp. 388-390
-
-
Morris, H.R.1
Katzenschlager, R.2
Janssen, J.C.3
Brown, J.M.4
Ozansoy, M.5
Quinn, N.6
Revesz, T.7
Rossor, M.N.8
Daniel, S.E.9
Wood, N.W.10
Lees, A.J.11
-
125
-
-
0034045148
-
Interleukin-1 and the immunogenetics of Alzheimer disease
-
Mrak RE, Griffin WS (2000) Interleukin-1 and the immunogenetics of Alzheimer disease. J Neuropathol Exp Neurol 59: 471-476
-
(2000)
J Neuropathol Exp Neurol
, vol.59
, pp. 471-476
-
-
Mrak, R.E.1
Griffin, W.S.2
-
126
-
-
0036150827
-
Alzheimer's disease-do tauists and baptists finally shake hands?
-
Mudher A, Lovestone S (2002) Alzheimer's disease-do tauists and baptists finally shake hands? Trends Neurosci 25: 22-26
-
(2002)
Trends Neurosci
, vol.25
, pp. 22-26
-
-
Mudher, A.1
Lovestone, S.2
-
127
-
-
0034468706
-
Crosslinking of α-synuclein by advanced glycation endproducts - An early pathophysiological step in Lewy body formation?
-
Munch G, Luth HJ, Wong A, Arendt T, Hirsch E, Ravid R, Riederer P (2000) Crosslinking of α-synuclein by advanced glycation endproducts - an early pathophysiological step in Lewy body formation? J Chem Neuroanat 20: 253-257
-
(2000)
J Chem Neuroanat
, vol.20
, pp. 253-257
-
-
Munch, G.1
Luth, H.J.2
Wong, A.3
Arendt, T.4
Hirsch, E.5
Ravid, R.6
Riederer, P.7
-
128
-
-
0034967925
-
The ubiquitin-proteasome pathway and proteasome inhibitors
-
Myung J, Kim KB, Crews CM (2001) The ubiquitin-proteasome pathway and proteasome inhibitors. Med Res Rev 21: 245-273
-
(2001)
Med Res Rev
, vol.21
, pp. 245-273
-
-
Myung, J.1
Kim, K.B.2
Crews, C.M.3
-
129
-
-
0034053173
-
Association of interleukin-1 gene polymorphisms with Alzheimer's disease
-
Nicoll JA, Mrak RE, Graham DI, Stewart J, Wilcock G, MacGowan S, Esiri MM, Murray LS, Dewar D, Love S, Moss T, Griffin WS (2000) Association of interleukin-1 gene polymorphisms with Alzheimer's disease. Ann Neurol 47: 365-368
-
(2000)
Ann Neurol
, vol.47
, pp. 365-368
-
-
Nicoll, J.A.1
Mrak, R.E.2
Graham, D.I.3
Stewart, J.4
Wilcock, G.5
MacGowan, S.6
Esiri, M.M.7
Murray, L.S.8
Dewar, D.9
Love, S.10
Moss, T.11
Griffin, W.S.12
-
130
-
-
0037186898
-
Apoptosis and age-related disorders: Role of caspase-dependent and caspase-independent pathways
-
Nicotera P (2002) Apoptosis and age-related disorders: role of caspase-dependent and caspase-independent pathways. Toxicol Lett 127: 189-195
-
(2002)
Toxicol Lett
, vol.127
, pp. 189-195
-
-
Nicotera, P.1
-
131
-
-
0034074468
-
Energy requirement for caspase activation and neuronal cell death
-
Nicotera P, Leist M, Fava E, Berliocchi L, Volbracht C (2000) Energy requirement for caspase activation and neuronal cell death. Brain Pathol 10: 276-282
-
(2000)
Brain Pathol
, vol.10
, pp. 276-282
-
-
Nicotera, P.1
Leist, M.2
Fava, E.3
Berliocchi, L.4
Volbracht, C.5
-
132
-
-
0034923434
-
Oxidative damage is the earliest event in Alzheimer disease
-
Nunomura A, Perry G, Aliev G, Hirai K, Takeda A, Balraj EK, Jones PK, Ghanbari H, Wataya T, Shimohama S, Chiba S, Atwood CS, Petersen RB, Smith MA (2001) Oxidative damage is the earliest event in Alzheimer disease. J Neuropathol Exp Neurol 60: 759-767
-
(2001)
J Neuropathol Exp Neurol
, vol.60
, pp. 759-767
-
-
Nunomura, A.1
Perry, G.2
Aliev, G.3
Hirai, K.4
Takeda, A.5
Balraj, E.K.6
Jones, P.K.7
Ghanbari, H.8
Wataya, T.9
Shimohama, S.10
Chiba, S.11
Atwood, C.S.12
Petersen, R.B.13
Smith, M.A.14
-
133
-
-
0034098189
-
Lipoperoxidation is selectively involved in progressive supranuclear palsy
-
Odetti P, Garibaldi S, Norese R, Angelini G, Marinelli L, Valentini S, Menini S, Traverso N, Zaccheo D, Siedlak S, Perry G, Smith MA, Tabaton M (2000) Lipoperoxidation is selectively involved in progressive supranuclear palsy. J Neuropathol Exp Neurol 59: 393-397
-
(2000)
J Neuropathol Exp Neurol
, vol.59
, pp. 393-397
-
-
Odetti, P.1
Garibaldi, S.2
Norese, R.3
Angelini, G.4
Marinelli, L.5
Valentini, S.6
Menini, S.7
Traverso, N.8
Zaccheo, D.9
Siedlak, S.10
Perry, G.11
Smith, M.A.12
Tabaton, M.13
-
134
-
-
0034962860
-
Mitochondria and degenerative disorders
-
Orth M, Schapira AHV (2001) Mitochondria and degenerative disorders. Am J Med Genet 106: 27-36
-
(2001)
Am J Med Genet
, vol.106
, pp. 27-36
-
-
Orth, M.1
Schapira, A.H.V.2
-
136
-
-
0037092442
-
A role for α-synuclein in the regulation of dopamine biosynthesis
-
Perez RG, Waymire JC, Lin E, Liu JJ, Guo F, Zigmond MJ (2002) A role for α-synuclein in the regulation of dopamine biosynthesis. J Neurosci 22: 3090-3099
-
(2002)
J Neurosci
, vol.22
, pp. 3090-3099
-
-
Perez, R.G.1
Waymire, J.C.2
Lin, E.3
Liu, J.J.4
Guo, F.5
Zigmond, M.J.6
-
137
-
-
1542747257
-
Neurofilament proteins are major targets of oxidative damage in the nervous system
-
Perry G, Liu Q, Wataya T, Shimohama S, Nunomura A, Siedlak SL, Sayre LL, Smith MA (2002) Neurofilament proteins are major targets of oxidative damage in the nervous system. J Neuropathol Exp Neurol 61: 456
-
(2002)
J Neuropathol Exp Neurol
, vol.61
, pp. 456
-
-
Perry, G.1
Liu, Q.2
Wataya, T.3
Shimohama, S.4
Nunomura, A.5
Siedlak, S.L.6
Sayre, L.L.7
Smith, M.A.8
-
138
-
-
1542747258
-
Oxidative mechanisms in neurodegenerative diseases
-
Dickson DW et al (eds) ISN Neuropathology Press, Los Angeles (in press)
-
Perry G, Srinivas R, Nunomura A, Smith MA (2003) Oxidative mechanisms in neurodegenerative diseases. In: Dickson DW et al (eds) Neurodegeneration and dementias. ISN Neuropathology Press, Los Angeles (in press)
-
(2003)
Neurodegeneration and Dementias
-
-
Perry, G.1
Srinivas, R.2
Nunomura, A.3
Smith, M.A.4
-
139
-
-
85087240063
-
Oxidative abnormalities as a window to Alzheimer disease
-
July 19-25, 2002, Abstr. # 4235
-
th International Conference on Alzheimer disease and Related Disorders, July 19-25, 2002, Abstr. # 4235
-
(2002)
th International Conference on Alzheimer Disease and Related Disorders
-
-
Perry, G.1
Zhu, X.2
Atwood, C.S.3
Numamura, A.4
Smith, M.A.5
-
140
-
-
0037315747
-
The impact of systemic infection on the progression of neurodegenerative disease
-
Perry VH, Newman TA, Cunningham C (2003) The impact of systemic infection on the progression of neurodegenerative disease. Nat Rev Neurosci 4: 103-112
-
(2003)
Nat Rev Neurosci
, vol.4
, pp. 103-112
-
-
Perry, V.H.1
Newman, T.A.2
Cunningham, C.3
-
141
-
-
0034915764
-
Mechanisms underlying ubiquitination
-
Pickart CM (2001) Mechanisms underlying ubiquitination. Annu Rev Biochem 70: 503-533
-
(2001)
Annu Rev Biochem
, vol.70
, pp. 503-533
-
-
Pickart, C.M.1
-
142
-
-
0033582421
-
The yeast frataxin homologue mediates mitochondrial iron efflux. Evidence for a mitochondrial iron cycle
-
Radisky DC, Babcock MC, Kaplan J (1999) The yeast frataxin homologue mediates mitochondrial iron efflux. Evidence for a mitochondrial iron cycle. J Biol Chem 274: 4497-4499
-
(1999)
J Biol Chem
, vol.274
, pp. 4497-4499
-
-
Radisky, D.C.1
Babcock, M.C.2
Kaplan, J.3
-
143
-
-
0035027964
-
Abortive apoptosis in Alzheimer's disease
-
Raina AK, Hochman A, Zhu X, Rottkamp CA, Nunomura A, Siedlak SL, Boux H, Castellani RJ, Perry G, Smith MA (2001) Abortive apoptosis in Alzheimer's disease. Acta Neuropathol 101: 305-310
-
(2001)
Acta Neuropathol
, vol.101
, pp. 305-310
-
-
Raina, A.K.1
Hochman, A.2
Zhu, X.3
Rottkamp, C.A.4
Nunomura, A.5
Siedlak, S.L.6
Boux, H.7
Castellani, R.J.8
Perry, G.9
Smith, M.A.10
-
144
-
-
12144286915
-
Apoptotic and oxidative indicators in Alzheimer disease
-
LeBlanc AC (ed) Humana Press, Totowa, NJ
-
nd ed. Humana Press, Totowa, NJ, pp. 225-246
-
(2002)
nd Ed.
, pp. 225-246
-
-
Raina, A.K.1
Sayre, L.M.2
Atwood, C.S.3
Rottkamp, C.A.4
Hochman, Y.5
Zhu, X.6
Obrenovic, M.E.7
Shimohama, S.8
Numamura, A.9
Takeda, A.10
Perry, G.11
Smith, M.A.12
-
145
-
-
17344367977
-
Behavioural abnormalities and selective neuronal loss in HD transgenic mice expressing mutated full-length HD cDNA
-
Reddy PH, Williams M, Charles V, Garrett L, Pike-Buchanan L, Whetsell WO Jr, Miller G, Tagle DA (1998) Behavioural abnormalities and selective neuronal loss in HD transgenic mice expressing mutated full-length HD cDNA. Nat Genet 20: 198-202
-
(1998)
Nat Genet
, vol.20
, pp. 198-202
-
-
Reddy, P.H.1
Williams, M.2
Charles, V.3
Garrett, L.4
Pike-Buchanan, L.5
Whetsell Jr., W.O.6
Miller, G.7
Tagle, D.A.8
-
146
-
-
0034320568
-
Mechanisms of apoptosis
-
Reed JC (2000) Mechanisms of apoptosis. Am J Pathol 157: 1415-1430
-
(2000)
Am J Pathol
, vol.157
, pp. 1415-1430
-
-
Reed, J.C.1
-
147
-
-
0035224161
-
Neural degeneration in Parkinson's disease
-
Riederer P, Reichmann H, Janetzky B, Sian J, Lesch KP, Lange KW, Double KL, Nagatsu T, Gerlach M (2001) Neural degeneration in Parkinson's disease. Adv Neurol 86: 125-136
-
(2001)
Adv Neurol
, vol.86
, pp. 125-136
-
-
Riederer, P.1
Reichmann, H.2
Janetzky, B.3
Sian, J.4
Lesch, K.P.5
Lange, K.W.6
Double, K.L.7
Nagatsu, T.8
Gerlach, M.9
-
148
-
-
0035664134
-
Activation of caspase-8 in the Alzheimer's disease brain
-
Rohn TT, Head E, Nesse WH, Cotman CW, Cribbs DH (2001) Activation of caspase-8 in the Alzheimer's disease brain. Neurobiol Dis 8: 1006-1016
-
(2001)
Neurobiol Dis
, vol.8
, pp. 1006-1016
-
-
Rohn, T.T.1
Head, E.2
Nesse, W.H.3
Cotman, C.W.4
Cribbs, D.H.5
-
149
-
-
0034830488
-
Caspases, apoptosis, and Alzheimer disease: Causation, correlation, and confusion
-
Roth KA (2001) Caspases, apoptosis, and Alzheimer disease: causation, correlation, and confusion. J Neuropathol Exp Neurol 60: 829-838
-
(2001)
J Neuropathol Exp Neurol
, vol.60
, pp. 829-838
-
-
Roth, K.A.1
-
150
-
-
0035865905
-
Redox-active iron mediates amyloid-β, toxicity
-
Rottkamp CA, Raina AK, Zhu X, Gaier E, Bush AI, Atwood CS, Chevion M, Perry G, Smith MA (2001) Redox-active iron mediates amyloid-β, toxicity. Free Radic Biol Med 30: 447-450
-
(2001)
Free Radic Biol Med
, vol.30
, pp. 447-450
-
-
Rottkamp, C.A.1
Raina, A.K.2
Zhu, X.3
Gaier, E.4
Bush, A.I.5
Atwood, C.S.6
Chevion, M.7
Perry, G.8
Smith, M.A.9
-
151
-
-
0033821703
-
Induction of neuronal death by α-synuclein
-
Saha AR, Ninkina NN, Hanger DP, Anderton BH, Davies AM, Buchman VL (2000) Induction of neuronal death by α-synuclein. Eur J Neursoci 12: 3073-3077
-
(2000)
Eur J Neursoci
, vol.12
, pp. 3073-3077
-
-
Saha, A.R.1
Ninkina, N.N.2
Hanger, D.P.3
Anderton, B.H.4
Davies, A.M.5
Buchman, V.L.6
-
152
-
-
0036434291
-
Heterogeneity of nigral and cortical Lewy bodies differentiated by amplified triple-labeling for α-synuclein, ubiquitin, and thiazin red
-
Sakamoto M, Uchihara T, Hayashi M, Nakamura A, Kikuchi E, Mizutani T, Mizusawa H, Hirai S (2002) Heterogeneity of nigral and cortical Lewy bodies differentiated by amplified triple-labeling for α-synuclein, ubiquitin, and thiazin red. Exp Neurol 177: 88-94
-
(2002)
Exp Neurol
, vol.177
, pp. 88-94
-
-
Sakamoto, M.1
Uchihara, T.2
Hayashi, M.3
Nakamura, A.4
Kikuchi, E.5
Mizutani, T.6
Mizusawa, H.7
Hirai, S.8
-
153
-
-
0032475931
-
Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions
-
Saudou F, Finkbeiner S, Devys D, Greenberg ME (1998) Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions. Cell 95: 55-66
-
(1998)
Cell
, vol.95
, pp. 55-66
-
-
Saudou, F.1
Finkbeiner, S.2
Devys, D.3
Greenberg, M.E.4
-
154
-
-
0035003439
-
Chemistry and biochemistry of oxidative stress in neurodegenerative disease
-
Sayre LM, Smith MA, Perry G (2001) Chemistry and biochemistry of oxidative stress in neurodegenerative disease. Curr Med Chem 8: 721-738
-
(2001)
Curr Med Chem
, vol.8
, pp. 721-738
-
-
Sayre, L.M.1
Smith, M.A.2
Perry, G.3
-
155
-
-
0036095285
-
Parkin localizes to the Lewy bodies of Parkinson disease and dementia with Lewy bodies
-
Schlossmacher MG, Frosch MP, Gai WP, Medina M, Sharma N, Forno L, Ochiishi T, Shimura H, Sharon R, Hattori N, Langston JW, Mizuno Y, Hyman BT, Selkoe DJ, Kosik KS (2002) Parkin localizes to the Lewy bodies of Parkinson disease and dementia with Lewy bodies. Am J Pathol 160: 1655-1667
-
(2002)
Am J Pathol
, vol.160
, pp. 1655-1667
-
-
Schlossmacher, M.G.1
Frosch, M.P.2
Gai, W.P.3
Medina, M.4
Sharma, N.5
Forno, L.6
Ochiishi, T.7
Shimura, H.8
Sharon, R.9
Hattori, N.10
Langston, J.W.11
Mizuno, Y.12
Hyman, B.T.13
Selkoe, D.J.14
Kosik, K.S.15
-
156
-
-
0036198110
-
Protein surveillance machinery in brains with spinocerebellar ataxia type 3: Redistribution and differential recruitment of 26S proteasome subunits and chaperones to neuronal intranuclear inclusions
-
Schmidt T, Lindenberg KS, Krebs A, Schöls L, Laccone F, Herms J, Rechsteiner M, Riess O, Landwehrmeyer GB (2002) Protein surveillance machinery in brains with spinocerebellar ataxia type 3: Redistribution and differential recruitment of 26S proteasome subunits and chaperones to neuronal intranuclear inclusions. Ann Neurol 51: 302-310
-
(2002)
Ann Neurol
, vol.51
, pp. 302-310
-
-
Schmidt, T.1
Lindenberg, K.S.2
Krebs, A.3
Schöls, L.4
Laccone, F.5
Herms, J.6
Rechsteiner, M.7
Riess, O.8
Landwehrmeyer, G.B.9
-
157
-
-
0032805805
-
On the survival time of a tangled neuron in the hippocampal CA4 region in parkinsonism dementia complex of Guam
-
Schwab C, Schulzer M, Steele JC, McGeer PL (1999) On the survival time of a tangled neuron in the hippocampal CA4 region in parkinsonism dementia complex of Guam. Neurobiol Aging 20: 57-63
-
(1999)
Neurobiol Aging
, vol.20
, pp. 57-63
-
-
Schwab, C.1
Schulzer, M.2
Steele, J.C.3
McGeer, P.L.4
-
158
-
-
0035404388
-
A close association of torsinA and α-synuclein in Lewy bodies: A fluorescence resonance energy transfer study
-
Sharma N, Hewett J, Ozelius LJ, Ramesh V, McLean PJ, Breakefield XO, Hyman BT (2001) A close association of torsinA and α-synuclein in Lewy bodies: a fluorescence resonance energy transfer study. Am J Pathol 159: 339-344
-
(2001)
Am J Pathol
, vol.159
, pp. 339-344
-
-
Sharma, N.1
Hewett, J.2
Ozelius, L.J.3
Ramesh, V.4
McLean, P.J.5
Breakefield, X.O.6
Hyman, B.T.7
-
159
-
-
0035139109
-
Cellular defenses against unfolded proteins: A cell biologist thinks about neurodegenerative diseases
-
Sherman MY, Goldberg AL (2001) Cellular defenses against unfolded proteins: a cell biologist thinks about neurodegenerative diseases. Neuron 29: 15-32
-
(2001)
Neuron
, vol.29
, pp. 15-32
-
-
Sherman, M.Y.1
Goldberg, A.L.2
-
160
-
-
0035854437
-
Ubiquitination of a new form of α-synuclein by parkin from human brain: Implications for Parkinson's disease
-
Shimura H, Schlossmacher MG, Hattori N, Frosch MP, Trockenbacher A, Schneider R, Mizuno Y, Kosik KS, Selkoe DJ (2001) Ubiquitination of a new form of α-synuclein by parkin from human brain: implications for Parkinson's disease. Science 293: 263-269
-
(2001)
Science
, vol.293
, pp. 263-269
-
-
Shimura, H.1
Schlossmacher, M.G.2
Hattori, N.3
Frosch, M.P.4
Trockenbacher, A.5
Schneider, R.6
Mizuno, Y.7
Kosik, K.S.8
Selkoe, D.J.9
-
161
-
-
0037414834
-
Ubiquitin conjugation is not required for the degradation of oxidized proteins by proteasome
-
Shringarpure R, Grune T, Mehlhase J, Davies KJ (2003) Ubiquitin conjugation is not required for the degradation of oxidized proteins by proteasome. J Biol Chem 278: 311-318
-
(2003)
J Biol Chem
, vol.278
, pp. 311-318
-
-
Shringarpure, R.1
Grune, T.2
Mehlhase, J.3
Davies, K.J.4
-
162
-
-
0033037919
-
Huntington's disease intranuclear inclusions contain truncated, ubiquitinated huntingtin protein
-
Sieradzan KA, Mechan AO, Jones L, Wanker EE, Nukina N, Mann DM (1999) Huntington's disease intranuclear inclusions contain truncated, ubiquitinated huntingtin protein. Exp Neurol 156: 92-99
-
(1999)
Exp Neurol
, vol.156
, pp. 92-99
-
-
Sieradzan, K.A.1
Mechan, A.O.2
Jones, L.3
Wanker, E.E.4
Nukina, N.5
Mann, D.M.6
-
164
-
-
0038788563
-
Pathogenesis: Oxidative stress, mitochondrial dysfunction and excitotoxicity
-
Factor SA, Weiner WJ (eds) Demos, New York
-
Simon DK, Beal MF (2002) Pathogenesis: oxidative stress, mitochondrial dysfunction and excitotoxicity. In: Factor SA, Weiner WJ (eds) Parkinson's disease. Diagnosis and management. Demos, New York, pp 281-290
-
(2002)
Parkinson's Disease. Diagnosis and Management
, pp. 281-290
-
-
Simon, D.K.1
Beal, M.F.2
-
165
-
-
0035704245
-
Endogenous brain cytokine mRNA and inflammatory responses to lipopolysaccharide are elevated in the Tg2576 transgenic mouse model of Alzheimer's disease
-
Sly LM, Krzesicki RF, Brashler JR, Buhl AE, McKinley DD, Carter DB, Chin JE (2001) Endogenous brain cytokine mRNA and inflammatory responses to lipopolysaccharide are elevated in the Tg2576 transgenic mouse model of Alzheimer's disease. Brain Res Bull 56: 581-588
-
(2001)
Brain Res Bull
, vol.56
, pp. 581-588
-
-
Sly, L.M.1
Krzesicki, R.F.2
Brashler, J.R.3
Buhl, A.E.4
McKinley, D.D.5
Carter, D.B.6
Chin, J.E.7
-
166
-
-
0035827318
-
Protein misfolding and disease; protein refolding and therapy
-
Soto C (2001) Protein misfolding and disease; protein refolding and therapy. FEBS Lett 498: 204-207
-
(2001)
FEBS Lett
, vol.498
, pp. 204-207
-
-
Soto, C.1
-
167
-
-
0037264120
-
Unfolding the role of protein misfolding in neurodegenerative diseases
-
Soto C (2003) Unfolding the role of protein misfolding in neurodegenerative diseases. Nat Rev Neurosci 4: 49-60
-
(2003)
Nat Rev Neurosci
, vol.4
, pp. 49-60
-
-
Soto, C.1
-
168
-
-
0032747486
-
Activation of caspase-3 in single neurons and autophagic granules of granulovacuolar degeneration in Alzheimer's disease. Evidence for apoptotic cell death
-
Stadelmann C, Deckwerth TL, Srinivasan A, Bancher C, Bruck W, Jellinger K, Lassmann H (1999) Activation of caspase-3 in single neurons and autophagic granules of granulovacuolar degeneration in Alzheimer's disease. Evidence for apoptotic cell death. Am J Pathol 155: 1459-1466
-
(1999)
Am J Pathol
, vol.155
, pp. 1459-1466
-
-
Stadelmann, C.1
Deckwerth, T.L.2
Srinivasan, A.3
Bancher, C.4
Bruck, W.5
Jellinger, K.6
Lassmann, H.7
-
169
-
-
0037303479
-
Nitric oxide-induced mitochondrial dysfunction: Implications for neurodegeneration
-
Stewart VC, Heales SJ (2003) Nitric oxide-induced mitochondrial dysfunction: implications for neurodegeneration. Free Radic Biol Med 34: 287-303
-
(2003)
Free Radic Biol Med
, vol.34
, pp. 287-303
-
-
Stewart, V.C.1
Heales, S.J.2
-
170
-
-
0036591852
-
Formation of hydrogen peroxide and hydroxyl radicals from Aβ and a-synuclein as a possible mechanism of cell death in Alzheimer's disease and Parkinson's disease
-
Tabner BJ, Turnbull S, El-Agnaf OM, Allsop D (2002) Formation of hydrogen peroxide and hydroxyl radicals from Aβ and a-synuclein as a possible mechanism of cell death in Alzheimer's disease and Parkinson's disease. Free Radic Biol Med 32: 1076-1083
-
(2002)
Free Radic Biol Med
, vol.32
, pp. 1076-1083
-
-
Tabner, B.J.1
Turnbull, S.2
El-Agnaf, O.M.3
Allsop, D.4
-
172
-
-
0036827031
-
Intraneuronal Alzheimer Aβ42 accumulates in multivesicular bodies and is associated with synaptic pathology
-
Takahashi RH, Milner TA, Li F, Nam EE, Edgar MA, Yamaguchi H, Beal MF, Xu H, Greengard P, Gouras GK (2002) Intraneuronal Alzheimer Aβ42 accumulates in multivesicular bodies and is associated with synaptic pathology. Am J Pathol 161: 1869-1879
-
(2002)
Am J Pathol
, vol.161
, pp. 1869-1879
-
-
Takahashi, R.H.1
Milner, T.A.2
Li, F.3
Nam, E.E.4
Edgar, M.A.5
Yamaguchi, H.6
Beal, M.F.7
Xu, H.8
Greengard, P.9
Gouras, G.K.10
-
173
-
-
0033756901
-
Increased caspase-3 and BAX immunoreactivity accompanying nuclear GAPDH translocation and neuronal apoptosis in Parkinson's disease
-
Tatton NA (2000) Increased caspase-3 and BAX immunoreactivity accompanying nuclear GAPDH translocation and neuronal apoptosis in Parkinson's disease. Exp Neurol 166: 29-43
-
(2000)
Exp Neurol
, vol.166
, pp. 29-43
-
-
Tatton, N.A.1
-
174
-
-
0032993576
-
Apoptosis in neurodegenerative disease: The role of mitochondria
-
Tatton WG, Olanow CW (1999) Apoptosis in neurodegenerative disease: The role of mitochondria. Biochem Biophys Acta 1410: 195-214
-
(1999)
Biochem Biophys Acta
, vol.1410
, pp. 195-214
-
-
Tatton, W.G.1
Olanow, C.W.2
-
175
-
-
0037294847
-
Pathogenic role of glial cells in Parkinson's disease
-
Teismann P, Tieu K, Cohen O, Choi DK, Wu du C, Marks D, Vila M, Jackson-Lewis V, Przedborski S (2003) Pathogenic role of glial cells in Parkinson's disease. Mov Disord 18: 121-129
-
(2003)
Mov Disord
, vol.18
, pp. 121-129
-
-
Teismann, P.1
Tieu, K.2
Cohen, O.3
Choi, D.K.4
Wu Du, C.5
Marks, D.6
Vila, M.7
Jackson-Lewis, V.8
Przedborski, S.9
-
176
-
-
0033624303
-
Sequence of Aβ-protein deposition in the human medial temporal lobe
-
Thal DR, Rüb U, Schultz C, Sassin I, Ghebremedhin E, Del Tredici K, Braak E, Braak H (2000) Sequence of Aβ-protein deposition in the human
-
(2000)
J Neuropathol Exp Neurol
, vol.59
, pp. 733-748
-
-
Thal, D.R.1
Rüb, U.2
Schultz, C.3
Sassin, I.4
Ghebremedhin, E.5
Del Tredici, K.6
Braak, E.7
Braak, H.8
-
177
-
-
0037172826
-
Phases of Aβ-deposition in the human brain and its relevance for the development of AD
-
Thal DR, Rüb U, Orantes M, Braak H (2002) Phases of Aβ-deposition in the human brain and its relevance for the development of AD. Neurology 58: 1781-1800
-
(2002)
Neurology
, vol.58
, pp. 1781-1800
-
-
Thal, D.R.1
Rüb, U.2
Orantes, M.3
Braak, H.4
-
179
-
-
0032816291
-
Loss-of-function mutations of SURF-1 are specifically associated with Leigh syndrome with cytochrome c oxidase deficiency
-
Tiranti V, Jaksch M, Hofmann S, Galimberti C, Hoertnagel K, Lulli L, Freisinger P, Bindoff L, Gerbitz KD, Comi GP, Uziel G, Zeviani M, Meitinger T (1999) Loss-of-function mutations of SURF-1 are specifically associated with Leigh syndrome with cytochrome c oxidase deficiency. Ann Neurol 46: 161-166
-
(1999)
Ann Neurol
, vol.46
, pp. 161-166
-
-
Tiranti, V.1
Jaksch, M.2
Hofmann, S.3
Galimberti, C.4
Hoertnagel, K.5
Lulli, L.6
Freisinger, P.7
Bindoff, L.8
Gerbitz, K.D.9
Comi, G.P.10
Uziel, G.11
Zeviani, M.12
Meitinger, T.13
-
180
-
-
0031474418
-
Contribution of somal Lewy bodies to neuronal death
-
Tompkins MM, Hill WD (1997) Contribution of somal Lewy bodies to neuronal death. Brain Res 775: 24-29
-
(1997)
Brain Res
, vol.775
, pp. 24-29
-
-
Tompkins, M.M.1
Hill, W.D.2
-
181
-
-
1542747256
-
Protein aggregation
-
Dickson DW et al (eds) ISN Neuropathology Press, Los Angeles (in press)
-
Trojanowski J (2003) Protein aggregation. In: Dickson DW et al (eds) Neurodegeneration and dementias. ISN Neuropathology Press, Los Angeles (in press)
-
(2003)
Neurodegeneration and Dementias
-
-
Trojanowski, J.1
-
182
-
-
0034513218
-
"Fatal attractions" of proteins. A comprehensive hypothetical mechanism underlying Alzheimer's disease and other neurodegenerative disorders
-
Trojanowski JQ, Lee VM (2000) "Fatal attractions" of proteins. A comprehensive hypothetical mechanism underlying Alzheimer's disease and other neurodegenerative disorders. Ann NY Acad Sci 924: 62-67
-
(2000)
Ann NY Acad Sci
, vol.924
, pp. 62-67
-
-
Trojanowski, J.Q.1
Lee, V.M.2
-
183
-
-
0035027982
-
Parkinson's disease and related neurodegenerative synucleinopathies linked to progressive accumulations of synuclein aggregates in brain
-
Trojanowski JQ, Lee VM (2001) Parkinson's disease and related neurodegenerative synucleinopathies linked to progressive accumulations of synuclein aggregates in brain. Parkinsonism Relat Disord 7: 247-251
-
(2001)
Parkinsonism Relat Disord
, vol.7
, pp. 247-251
-
-
Trojanowski, J.Q.1
Lee, V.M.2
-
184
-
-
0031762949
-
Fatal attractions - Abnormal protein aggregation and neuron death in Parkinson's disease and Lewy body-dementia
-
Trojanowski JQ, Goedert M, Iwatsubo T, Lee VMY (1998) Fatal attractions - abnormal protein aggregation and neuron death in Parkinson's disease and Lewy body-dementia. Cell Death Different 5: 832-837
-
(1998)
Cell Death Different
, vol.5
, pp. 832-837
-
-
Trojanowski, J.Q.1
Goedert, M.2
Iwatsubo, T.3
Lee, V.M.Y.4
-
185
-
-
0036153571
-
What does it mean to be natively unfolded?
-
Uversky VN (2002) What does it mean to be natively unfolded? Eur J Biochem 269: 2-12
-
(2002)
Eur J Biochem
, vol.269
, pp. 2-12
-
-
Uversky, V.N.1
-
186
-
-
0035941201
-
Metal-triggered structural transformations, aggregation, and fibrillation of human α-synuclein. A possible molecular NK between Parkinson's disease and heavy metal exposure
-
Uversky VN, Li J, Fink AL (2001) Metal-triggered structural transformations, aggregation, and fibrillation of human α-synuclein. A possible molecular NK between Parkinson's disease and heavy metal exposure. J Biol Chem 276: 44284-44296
-
(2001)
J Biol Chem
, vol.276
, pp. 44284-44296
-
-
Uversky, V.N.1
Li, J.2
Fink, A.L.3
-
187
-
-
0032716335
-
Visualization of defective mitochondrial function in skeletal muscle fibers of patients with sporadic amyotrophic lateral sclerosis
-
Vielhaber S, Winkler K, Kirches E, Kunz D, Buchner M, Feistner H, Elger CE, Ludolph AC, Riepe MW, Kunz WS (1999) Visualization of defective mitochondrial function in skeletal muscle fibers of patients with sporadic amyotrophic lateral sclerosis. J Neurol Sci 169: 133-139
-
(1999)
J Neurol Sci
, vol.169
, pp. 133-139
-
-
Vielhaber, S.1
Winkler, K.2
Kirches, E.3
Kunz, D.4
Buchner, M.5
Feistner, H.6
Elger, C.E.7
Ludolph, A.C.8
Riepe, M.W.9
Kunz, W.S.10
-
188
-
-
0037957556
-
Engineered modeling and the secrets of Parkinson's disease
-
Vila M, Wu DC, Przedborski S (2001) Engineered modeling and the secrets of Parkinson's disease. TINS 24[Suppl]: S49-S55
-
(2001)
TINS
, vol.24
, Issue.SUPPL.
-
-
Vila, M.1
Wu, D.C.2
Przedborski, S.3
-
190
-
-
0033956278
-
Calpain and caspase; can you tell the difference?
-
Wang KKW (2000) Calpain and caspase; can you tell the difference? Trends Neurol Sci 23: 20-26
-
(2000)
Trends Neurol Sci
, vol.23
, pp. 20-26
-
-
Kkw, W.1
-
191
-
-
0035664213
-
Histological evidence of protein aggregation in mutant SOD1 transgenic mice and in amyotrophic lateral sclerosis neural tissues
-
Watanabe M, Dykes-Hoberg M, Culotta VC, Price DL, Wong PC, Rothstein JD (2001) Histological evidence of protein aggregation in mutant SOD1 transgenic mice and in amyotrophic lateral sclerosis neural tissues. Neurobiol Dis 8: 933-941
-
(2001)
Neurobiol Dis
, vol.8
, pp. 933-941
-
-
Watanabe, M.1
Dykes-Hoberg, M.2
Culotta, V.C.3
Price, D.L.4
Wong, P.C.5
Rothstein, J.D.6
-
192
-
-
0037157533
-
Defining neurodegenerative diseases
-
Williams A (2002) Defining neurodegenerative diseases. BMJ 324: 1465-1466
-
(2002)
BMJ
, vol.324
, pp. 1465-1466
-
-
Williams, A.1
-
193
-
-
0032800818
-
Intracellular APP processing and Aβ production in Alzheimer disease
-
Wilson CA, Doms RW, Lee VM (1999) Intracellular APP processing and Aβ production in Alzheimer disease. J Neuropathol Exp Neurol 58: 787-794
-
(1999)
J Neuropathol Exp Neurol
, vol.58
, pp. 787-794
-
-
Wilson, C.A.1
Doms, R.W.2
Lee, V.M.3
-
194
-
-
0034123691
-
Mechanisms of neurodegenerative disorders, part 1. Protein aggregates
-
Wolozin B, Behl C (2000) Mechanisms of neurodegenerative disorders, part 1. Protein aggregates. Arch Neurol 57: 793-796
-
(2000)
Arch Neurol
, vol.57
, pp. 793-796
-
-
Wolozin, B.1
Behl, C.2
-
195
-
-
0035976590
-
Advanced glycation endproducts co-localize with inducible nitric oxide synthase in Alzheimer's disease
-
Wong A, Luth HJ, Deuther-Conrad W, Dukic-Stefanovic S, Gasic-Milenkovic J, Arendt T, Munch G (2001) Advanced glycation endproducts co-localize with inducible nitric oxide synthase in Alzheimer's disease. Brain Res 920: 32-40
-
(2001)
Brain Res
, vol.920
, pp. 32-40
-
-
Wong, A.1
Luth, H.J.2
Deuther-Conrad, W.3
Dukic-Stefanovic, S.4
Gasic-Milenkovic, J.5
Arendt, T.6
Munch, G.7
-
196
-
-
0036724204
-
Iron (III) induces aggregation of hyperphosphorylated tau and its reduction to iron (II) reverses the aggregation: Implications in the formation of neurofibrillary tangles of Alzheimer's disease
-
Yamamoto A, Shin RW, Hasegawa K, Naiki H, Sato H, Yoshimasu F, Kitamoto T (2002) Iron (III) induces aggregation of hyperphosphorylated tau and its reduction to iron (II) reverses the aggregation: implications in the formation of neurofibrillary tangles of Alzheimer's disease. J Neurochem 82: 1137-1147
-
(2002)
J Neurochem
, vol.82
, pp. 1137-1147
-
-
Yamamoto, A.1
Shin, R.W.2
Hasegawa, K.3
Naiki, H.4
Sato, H.5
Yoshimasu, F.6
Kitamoto, T.7
-
198
-
-
0037317988
-
Transglutaminase activity, protein, and mRNA expression are increased in progressive supranuclear palsy
-
Zemaitaitis MO, Kim SY, Halverson RA, Troncoso JC, Lee JM, Muma NA (2003) Transglutaminase activity, protein, and mRNA expression are increased in progressive supranuclear palsy. J Neuropathol Exp Neurol 62: 173-184
-
(2003)
J Neuropathol Exp Neurol
, vol.62
, pp. 173-184
-
-
Zemaitaitis, M.O.1
Kim, S.Y.2
Halverson, R.A.3
Troncoso, J.C.4
Lee, J.M.5
Muma, N.A.6
-
199
-
-
0032911488
-
Parkinson's disease is associated with oxidative damage to cytoplasmic DNA and RNA in substantia nigra neurons
-
Zhang J, Perry G, Smith MA, Robertson D, Olson SJ, Graham DG, Montine TJ (1999) Parkinson's disease is associated with oxidative damage to cytoplasmic DNA and RNA in substantia nigra neurons. Am J Pathol 154: 1423-1429
-
(1999)
Am J Pathol
, vol.154
, pp. 1423-1429
-
-
Zhang, J.1
Perry, G.2
Smith, M.A.3
Robertson, D.4
Olson, S.J.5
Graham, D.G.6
Montine, T.J.7
-
200
-
-
0034935036
-
A novel pantothenate kinase gene (PANK2) is defective in Hallervorden-Spatz syndrome
-
Zhou B, Westaway SK, Levinson B, Johnson MA, Gitschier J, Hayflick SJ (2001) A novel pantothenate kinase gene (PANK2) is defective in Hallervorden-Spatz syndrome. Nat Genet 28: 345-349
-
(2001)
Nat Genet
, vol.28
, pp. 345-349
-
-
Zhou, B.1
Westaway, S.K.2
Levinson, B.3
Johnson, M.A.4
Gitschier, J.5
Hayflick, S.J.6
-
201
-
-
0036468957
-
Overexpression of human α-synuclein causes dopamine neuron death in primary human mesencephalic culture
-
Zhou W, Schaack J, Zawada WM, Freed CR (2002) Overexpression of human α-synuclein causes dopamine neuron death in primary human mesencephalic culture. Brain Res 926: 42-50
-
(2002)
Brain Res
, vol.926
, pp. 42-50
-
-
Zhou, W.1
Schaack, J.2
Zawada, W.M.3
Freed, C.R.4
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