Proteolytic processing of familial British dementia-associated BRI variants: Evidence for enhanced intracellular accumulation of amyloidogenic peptides

Journal of Biological Chemistry

Volumn 277, Issue 3, 2002, Pages 1872-1877

  Kim, Seong Hun ^a   Creemers, John W M ^b   Chu, Su ^a   Thinakaran, Gopal ^b   Sisodia, Sangram S ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

GENES; NEUROLOGY;

PROTEOLYTIC PROCESSES;

PROTEINS;

ALPHA 1 ANTITRYPSIN; BRI PROTEIN; FURIN; GENE PRODUCT; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DEGENERATIVE DISEASE; DEMENTIA; DOSE RESPONSE; ENZYME ACTIVITY; FAMILIAL BRITISH DEMENTIA; GENE EXPRESSION; GENE MUTATION; GENETIC CODE; GENETIC VARIABILITY; MOUSE; NERVE CELL LESION; NEUROPATHOLOGY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN PROCESSING;

ALPHA 1-ANTITRYPSIN; AMYLOID; CELL COMPARTMENTATION; DEMENTIA; HUMANS; HYDROLYSIS; KINETICS; MUTATION; PEPTIDE FRAGMENTS; PROTEIN PROCESSING, POST-TRANSLATIONAL;

ANIMALIA;

EID: 0037127261     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M108739200     Document Type: Article

References (31)