-
1
-
-
0030805622
-
A generalised increase in protein carbonyls in the brain in Parkinson's but not incidental Lewy body disease
-
Alam, Z.I., Daniel, S.E., Lees, A.J., Marsden, D.C., Jenner, P. & Halliwell, B. (1997) A generalised increase in protein carbonyls in the brain in Parkinson's but not incidental Lewy body disease. J. Neurochem., 69, 1326-1329.
-
(1997)
J. Neurochem.
, vol.69
, pp. 1326-1329
-
-
Alam, Z.I.1
Daniel, S.E.2
Lees, A.J.3
Marsden, D.C.4
Jenner, P.5
Halliwell, B.6
-
2
-
-
0036468432
-
Chaperone suppression of alpha-synuclein toxicity in a drosophila model of Parkinson's disease
-
Auluck, P.K., Chan, E., Trojanowski, J.Q., Lee, V. & Bonini, N.M. (2002) Chaperone suppression of alpha-synuclein toxicity in a drosophila model of Parkinson's disease. Science, 295, 865-868.
-
(2002)
Science
, vol.295
, pp. 865-868
-
-
Auluck, P.K.1
Chan, E.2
Trojanowski, J.Q.3
Lee, V.4
Bonini, N.M.5
-
3
-
-
0032930953
-
Microtubules and neuronal polarity: Lessons from mitosis
-
Baas, P.W. (1999) Microtubules and neuronal polarity: Lessons from mitosis. Neuron, 22, 23-31.
-
(1999)
Neuron
, vol.22
, pp. 23-31
-
-
Baas, P.W.1
-
4
-
-
0035947372
-
Impairment of the ubiquitin-proteasome system by protein aggregation
-
Bence, N.F., Sampat, R.M. & Kopito, R.R. (2001) Impairment of the ubiquitin-proteasome system by protein aggregation. Science, 292, 1552-1555.
-
(2001)
Science
, vol.292
, pp. 1552-1555
-
-
Bence, N.F.1
Sampat, R.M.2
Kopito, R.R.3
-
5
-
-
0034776095
-
Parkin ubiquitinates the alpha-synuclein-interacting protein, synphilin-1: Implications for Lewy-body formation in Parkinson disease
-
Chung, K.K., Zhang, Y., Lim, K.L., Tanaka, Y., Huang, H., Gao, J., Ross, C.A., Dawson, V.L. & Dawson, T.M. (2001) Parkin ubiquitinates the alpha-synuclein-interacting protein, synphilin-1: Implications for Lewy-body formation in Parkinson disease. Nature Med., 7, 1144-1150.
-
(2001)
Nature Med.
, vol.7
, pp. 1144-1150
-
-
Chung, K.K.1
Zhang, Y.2
Lim, K.L.3
Tanaka, Y.4
Huang, H.5
Gao, J.6
Ross, C.A.7
Dawson, V.L.8
Dawson, T.M.9
-
6
-
-
0028218025
-
Pericentrin, a highly conserved centrosome protein involved in microtubule organization
-
Doxsey, S.J., Stein, P., Evans, L., Calarco, P.D. & Kirschner, M. (1994) Pericentrin, a highly conserved centrosome protein involved in microtubule organization. Cell, 76, 639-650.
-
(1994)
Cell
, vol.76
, pp. 639-650
-
-
Doxsey, S.J.1
Stein, P.2
Evans, L.3
Calarco, P.D.4
Kirschner, M.5
-
7
-
-
0032915723
-
Numerous and widespread alpha-synuclein-negative Lewy bodies in an asymptomatic patient
-
van Duinen, S.G., Lammers, G.J., Maat-Schieman, M.L. & Roos, R.A. (1999) Numerous and widespread alpha-synuclein-negative Lewy bodies in an asymptomatic patient. Acta Neuropathol. (Berl.), 97, 533-539.
-
(1999)
Acta Neuropathol. (Berl.)
, vol.97
, pp. 533-539
-
-
Van Duinen, S.G.1
Lammers, G.J.2
Maat-Schieman, M.L.3
Roos, R.A.4
-
8
-
-
0035939105
-
The expression of mRNAs for the proteasome complex is developmentally regulated in the rat mesencephalon
-
El-Khodor, B.F., Kholodilov, N.G., Yarygina, O. & Burke, R.E. (2001) The expression of mRNAs for the proteasome complex is developmentally regulated in the rat mesencephalon. Brain Res. Dev. Brain Res., 129, 47-56.
-
(2001)
Brain Res. Dev. Brain Res.
, vol.129
, pp. 47-56
-
-
El-Khodor, B.F.1
Kholodilov, N.G.2
Yarygina, O.3
Burke, R.E.4
-
9
-
-
0034614416
-
Activity and regulation of the centrosome-associated proteasome
-
Fabunmi, R.P., Wigley, W.C., Thomas, P.J. & DeMartino, G.N. (2000) Activity and regulation of the centrosome-associated proteasome. J. Biol. Chem., 275, 409-413.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 409-413
-
-
Fabunmi, R.P.1
Wigley, W.C.2
Thomas, P.J.3
DeMartino, G.N.4
-
10
-
-
0032502719
-
Lactacystin, proteasome function, and cell fate
-
Fenteany, G. & Schreiber, S.L. (1998) Lactacystin, proteasome function, and cell fate. J. Biol. Chem., 273, 8545-8548.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 8545-8548
-
-
Fenteany, G.1
Schreiber, S.L.2
-
11
-
-
0030606288
-
Pathological lesions of Alzheimer's disease and dementia with Lewy bodies brains exhibit immunoreactivity to an ATPase that is a regulatory subunit of the 26S proteasome
-
Fergusson, J., Landon, M., Lowe, J., Dawson, S.P., Layfield, R., Hanger, D.P. & Mayer, R.J. (1996) Pathological lesions of Alzheimer's disease and dementia with Lewy bodies brains exhibit immunoreactivity to an ATPase that is a regulatory subunit of the 26S proteasome. Neurosci Lett., 219, 167-170.
-
(1996)
Neurosci Lett.
, vol.219
, pp. 167-170
-
-
Fergusson, J.1
Landon, M.2
Lowe, J.3
Dawson, S.P.4
Layfield, R.5
Hanger, D.P.6
Mayer, R.J.7
-
12
-
-
0031962268
-
Increased protein oxidation in human substantia nigra pars compacta in comparison with basal ganglia and prefrontal cortex measured with an improved dinitrophenylhydrazine assay
-
Floor, E. & Wetzel, M.G. (1998) Increased protein oxidation in human substantia nigra pars compacta in comparison with basal ganglia and prefrontal cortex measured with an improved dinitrophenylhydrazine assay. J. Neurochem., 70, 268-275.
-
(1998)
J. Neurochem.
, vol.70
, pp. 268-275
-
-
Floor, E.1
Wetzel, M.G.2
-
13
-
-
0029981526
-
Neuropathology of Parkinson's disease
-
Forno, L.S. (1996) Neuropathology of Parkinson's disease. J. Neuropathol. Exp. Neurol., 55, 259-272.
-
(1996)
J. Neuropathol. Exp. Neurol.
, vol.55
, pp. 259-272
-
-
Forno, L.S.1
-
14
-
-
0035680611
-
Aggresome formation in liver cells in response to different toxic mechanisms: Role of the ubiquitin-proteasome pathway and the frameshift mutant of ubiquitin
-
French, B.A., van Leeuwen, F., Riley, N.E., Yuan, Q.X., Bardag-Gorce, F., Gaal, K., Lue, Y.H., Marceau, N. & French, S.W. (2001) Aggresome formation in liver cells in response to different toxic mechanisms: Role of the ubiquitin-proteasome pathway and the frameshift mutant of ubiquitin. Exp. Mol. Pathol., 71, 241-246.
-
(2001)
Exp. Mol. Pathol.
, vol.71
, pp. 241-246
-
-
French, B.A.1
Van Leeuwen, F.2
Riley, N.E.3
Yuan, Q.X.4
Bardag-Gorce, F.5
Gaal, K.6
Lue, Y.H.7
Marceau, N.8
French, S.W.9
-
15
-
-
0028070372
-
Production and characterization of monoclonal antibodies specific to multi-ubiquitin chains of polyubiquitinated proteins
-
Fujimuro, M., Sawada, H. & Yokosawa, H. (1994) Production and characterization of monoclonal antibodies specific to multi-ubiquitin chains of polyubiquitinated proteins. FEBS Lett., 349, 173-180.
-
(1994)
FEBS Lett.
, vol.349
, pp. 173-180
-
-
Fujimuro, M.1
Sawada, H.2
Yokosawa, H.3
-
16
-
-
0035050618
-
Caretaker or undertaker? The role of the proteasome in aging
-
Gaczynska, M., Osmulski, P.A. & Ward, W.F. (2001) Caretaker or undertaker? The role of the proteasome in aging. Mech. Ageing Dev., 122, 235-254.
-
(2001)
Mech. Ageing Dev.
, vol.122
, pp. 235-254
-
-
Gaczynska, M.1
Osmulski, P.A.2
Ward, W.F.3
-
17
-
-
0034602442
-
Oxidative damage linked to neurodegeneration by selective alpha-synuclein nitration in synucleinopathy lesions
-
Giasson, B.I., Duda, J.E., Murray, I.V., Chen, Q., Souza, J.M., Hurtig, H.I., Ischiropoulos, H., Trojanowski, J.Q. & Lee, V.M. (2000) Oxidative damage linked to neurodegeneration by selective alpha-synuclein nitration in synucleinopathy lesions. Science, 290, 985-989.
-
(2000)
Science
, vol.290
, pp. 985-989
-
-
Giasson, B.I.1
Duda, J.E.2
Murray, I.V.3
Chen, Q.4
Souza, J.M.5
Hurtig, H.I.6
Ischiropoulos, H.7
Trojanowski, J.Q.8
Lee, V.M.9
-
18
-
-
0023898945
-
The relevance of the Lewy body to the pathogenesis of idiopathic Parkinson's disease
-
Gibb, W.R. & Lees, A.J. (1988) The relevance of the Lewy body to the pathogenesis of idiopathic Parkinson's disease. J. Neurol. Neurosurg. Psychiatry, 51, 745-752.
-
(1988)
J. Neurol. Neurosurg. Psychiatry
, vol.51
, pp. 745-752
-
-
Gibb, W.R.1
Lees, A.J.2
-
19
-
-
0343527226
-
alpha-Synuclein immunoreactivity in dementia with Lewy bodies: Morphological staging and comparison with ubiquitin immunostaining
-
Gomez-Tortosa, E., Newell, K., Irizarry, M.C., Sanders, J.L. & Hyman, B.T. (2000) alpha-Synuclein immunoreactivity in dementia with Lewy bodies: Morphological staging and comparison with ubiquitin immunostaining. Acta Neuropathol. (Berl.), 99, 352-357.
-
(2000)
Acta Neuropathol. (Berl.)
, vol.99
, pp. 352-357
-
-
Gomez-Tortosa, E.1
Newell, K.2
Irizarry, M.C.3
Sanders, J.L.4
Hyman, B.T.5
-
20
-
-
0031939204
-
Protein nitration in Parkinson's disease
-
Good, P.F., Hsu, A., Werner, P., Perl, D.P. & Olanow, C.W. (1998) Protein nitration in Parkinson's disease. J. Neuropathol. Exp. Neurol., 57, 338-342.
-
(1998)
J. Neuropathol. Exp. Neurol.
, vol.57
, pp. 338-342
-
-
Good, P.F.1
Hsu, A.2
Werner, P.3
Perl, D.P.4
Olanow, C.W.5
-
21
-
-
0030059868
-
L-DOPA up-regulates glutathione and protects mesencephalic cultures against oxidative stress
-
Han, S.K., Mytilineou, C. & Cohen, G. (1996) L-DOPA up-regulates glutathione and protects mesencephalic cultures against oxidative stress. J. Neurochem., 66, 501-510.
-
(1996)
J. Neurochem.
, vol.66
, pp. 501-510
-
-
Han, S.K.1
Mytilineou, C.2
Cohen, G.3
-
22
-
-
0037040541
-
Molecular chaperones in the cytosol: From nascent chain to folded protein
-
Hartl, F.U. & Hayer-Hartl, M. (2002) Molecular chaperones in the cytosol: From nascent chain to folded protein. Science, 295, 1852-1858.
-
(2002)
Science
, vol.295
, pp. 1852-1858
-
-
Hartl, F.U.1
Hayer-Hartl, M.2
-
23
-
-
0036500862
-
Perinuclear localization of huntingtin as a consequence of its binding to microtubules through an interaction with beta-tubulin: Relevance to Huntington's disease
-
Hoffner, G., Kahlem, P. & Djian, P. (2002) Perinuclear localization of huntingtin as a consequence of its binding to microtubules through an interaction with beta-tubulin: Relevance to Huntington's disease. J. Cell Sci., 115, 941-948.
-
(2002)
J. Cell Sci.
, vol.115
, pp. 941-948
-
-
Hoffner, G.1
Kahlem, P.2
Djian, P.3
-
24
-
-
0030830270
-
Immunocytochemical co-localization of the proteasome in ubiquitinated structures in neurodegenerative diseases and the elderly
-
Ii, K., Ito, H., Tanaka, K. & Hirano, A. (1997) Immunocytochemical co-localization of the proteasome in ubiquitinated structures in neurodegenerative diseases and the elderly. J. Neuropathol. Exp. Neurol., 56, 125-131.
-
(1997)
J. Neuropathol. Exp. Neurol.
, vol.56
, pp. 125-131
-
-
Ii, K.1
Ito, H.2
Tanaka, K.3
Hirano, A.4
-
25
-
-
0031687793
-
Understanding cell death in Parkinson's disease
-
Jenner, P. & Olanow, C.W. (1998) Understanding cell death in Parkinson's disease. Ann. Neurol., 44, S72-S84.
-
(1998)
Ann. Neurol.
, vol.44
-
-
Jenner, P.1
Olanow, C.W.2
-
26
-
-
0032824809
-
Axonal transport of synucleins is mediated by all rate components
-
Jensen, P.H., Li, J.Y., Dahlstrom, A. & Dotti, C.G. (1999) Axonal transport of synucleins is mediated by all rate components. Eur. J. Neurosci., 11, 3369-3376.
-
(1999)
Eur. J. Neurosci.
, vol.11
, pp. 3369-3376
-
-
Jensen, P.H.1
Li, J.Y.2
Dahlstrom, A.3
Dotti, C.G.4
-
27
-
-
0032576605
-
Aggresomes: A cellular response to misfolded proteins
-
Johnston, J.A., Ward, C.L. & Kopito, R.R. (1998) Aggresomes: A cellular response to misfolded proteins. J. Cell Biol., 143, 1883-1898.
-
(1998)
J. Cell Biol.
, vol.143
, pp. 1883-1898
-
-
Johnston, J.A.1
Ward, C.L.2
Kopito, R.R.3
-
28
-
-
0033621398
-
Aberrant protein deposition and neurological disease
-
Kaytor, M.D. & Warren, S.T. (1999) Aberrant protein deposition and neurological disease. J. Biol. Chem., 274, 37507-37510.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 37507-37510
-
-
Kaytor, M.D.1
Warren, S.T.2
-
29
-
-
0034578389
-
Aggresomes, inclusion bodies and protein aggregation
-
Kopito, R.R. (2000) Aggresomes, inclusion bodies and protein aggregation. Trends Cell Biol., 10, 524-530.
-
(2000)
Trends Cell Biol.
, vol.10
, pp. 524-530
-
-
Kopito, R.R.1
-
30
-
-
0030814627
-
Synaptically coupled central nervous system neurons lack centrosomal gamma-tubulin
-
Leask, A., Obrietan, K. & Stearns, T. (1997) Synaptically coupled central nervous system neurons lack centrosomal gamma-tubulin. Neurosci. Lett., 229, 17-20.
-
(1997)
Neurosci. Lett.
, vol.229
, pp. 17-20
-
-
Leask, A.1
Obrietan, K.2
Stearns, T.3
-
31
-
-
0032190090
-
The ubiquitin pathway in Parkinson's disease
-
Leroy, E., Boyer, R., Auburger, G., Leube, B., Ulm, G., Mezey, E., Harta, G., Brownstein, M.J., Jonnalagada, S., Chernova, T., Dehejia, A., Lavedan, C., Gasser, T., Steinbach, P.J., Wilkinson, K.D. et al. (1998) The ubiquitin pathway in Parkinson's disease. Nature, 395, 451-452.
-
(1998)
Nature
, vol.395
, pp. 451-452
-
-
Leroy, E.1
Boyer, R.2
Auburger, G.3
Leube, B.4
Ulm, G.5
Mezey, E.6
Harta, G.7
Brownstein, M.J.8
Jonnalagada, S.9
Chernova, T.10
Dehejia, A.11
Lavedan, C.12
Gasser, T.13
Steinbach, P.J.14
Wilkinson, K.D.15
-
32
-
-
0034309848
-
Nuclear magnetic relaxation dispersion profiles of substantia nigra pars compacta in Parkinson's disease patients are consistent with protein aggregation
-
Lopiano, L., Fasano, M., Giraudo, S., Digilio, G., Koenig, S.H., Torre, E., Bergamasco, B. & Aime, S. (2000) Nuclear magnetic relaxation dispersion profiles of substantia nigra pars compacta in Parkinson's disease patients are consistent with protein aggregation. Neurochem. Int., 37, 331-336.
-
(2000)
Neurochem. Int.
, vol.37
, pp. 331-336
-
-
Lopiano, L.1
Fasano, M.2
Giraudo, S.3
Digilio, G.4
Koenig, S.H.5
Torre, E.6
Bergamasco, B.7
Aime, S.8
-
33
-
-
0025326719
-
Ubiquitin carboxyl-terminal hydrolase (PGP 9.5) is selectively present in ubiquitinated inclusion bodies characteristic of human neurodegenerative diseases
-
Lowe, J., McDermott, H., Landon, M., Mayer, R.J. & Wilkinson, K.D. (1990) Ubiquitin carboxyl-terminal hydrolase (PGP 9.5) is selectively present in ubiquitinated inclusion bodies characteristic of human neurodegenerative diseases. J. Pathol., 161, 153-160.
-
(1990)
J. Pathol.
, vol.161
, pp. 153-160
-
-
Lowe, J.1
McDermott, H.2
Landon, M.3
Mayer, R.J.4
Wilkinson, K.D.5
-
34
-
-
0035910069
-
Wild-type PrP and a mutant associated with prion disease are subject to retrograde transport and proteasome degradation
-
Ma, J. & Lindquist, S. (2001) Wild-type PrP and a mutant associated with prion disease are subject to retrograde transport and proteasome degradation. Proc. Natl Acad. Sci. USA, 98, 14955-14960.
-
(2001)
Proc. Natl Acad. Sci. USA
, vol.98
, pp. 14955-14960
-
-
Ma, J.1
Lindquist, S.2
-
35
-
-
0028297514
-
Multicatalytic proteinase is associated with characteristic oval structures in cortical Lewy bodies: An immunocytochemical study with light and electron microscopy
-
Masaki, T., Ishiura, S., Sugita, H. & Kwak, S. (1994) Multicatalytic proteinase is associated with characteristic oval structures in cortical Lewy bodies: An immunocytochemical study with light and electron microscopy. J. Neurol. Sci., 122, 127-134.
-
(1994)
J. Neurol. Sci.
, vol.122
, pp. 127-134
-
-
Masaki, T.1
Ishiura, S.2
Sugita, H.3
Kwak, S.4
-
36
-
-
0037025111
-
Selective loss of 20S proteasome alpha-subunits in the substantia nigra pars compacta in Parkinson's disease
-
McNaught, K.S., Belezaire, R., Jenner, P., Olanow, C.W. & Isacson, O. (2002a) Selective loss of 20S proteasome alpha-subunits in the substantia nigra pars compacta in Parkinson's disease. Neurosci. Lett., 326, 155-158.
-
(2002)
Neurosci. Lett.
, vol.326
, pp. 155-158
-
-
McNaught, K.S.1
Belezaire, R.2
Jenner, P.3
Olanow, C.W.4
Isacson, O.5
-
37
-
-
0012089058
-
Altered proteasomal function in sporadic Parkinson's disease
-
in press
-
McNaught, K.S., Belizaire, R., Isacson, O., Jenner, P. & Olanow, C.W. (2002b) Altered proteasomal function in sporadic Parkinson's disease. Exp. Neurol., in press.
-
(2002)
Exp. Neurol.
-
-
McNaught, K.S.1
Belizaire, R.2
Isacson, O.3
Jenner, P.4
Olanow, C.W.5
-
38
-
-
0035910634
-
Proteasomal function is impaired in substantia nigra in Parkinson's disease
-
McNaught, K.S. & Jenner, P. (2001) Proteasomal function is impaired in substantia nigra in Parkinson's disease. Neurosci. Lett., 297, 191-194.
-
(2001)
Neurosci. Lett.
, vol.297
, pp. 191-194
-
-
McNaught, K.S.1
Jenner, P.2
-
39
-
-
0035430788
-
Failure of the ubiquitin-proteasome system in Parkinson's disease
-
McNaught, K.S., Olanow, C.W., Halliwell, B., Isacson, O. & Jenner, P. (2001) Failure of the ubiquitin-proteasome system in Parkinson's disease. Nature Rev. Neurosci., 2, 589-594.
-
(2001)
Nature Rev. Neurosci.
, vol.2
, pp. 589-594
-
-
McNaught, K.S.1
Olanow, C.W.2
Halliwell, B.3
Isacson, O.4
Jenner, P.5
-
40
-
-
0344758360
-
Glial cells mediate toxicity in glutathione-depleted mesencephalic cultures
-
Mytilineou, C., Kokotos Leonardi, E.T., Kramer, B.C., Jamindar, T. & Olanow, C.W. (1999) Glial cells mediate toxicity in glutathione-depleted mesencephalic cultures. J. Neurochem., 73, 112-119.
-
(1999)
J. Neurochem.
, vol.73
, pp. 112-119
-
-
Mytilineou, C.1
Kokotos Leonardi, E.T.2
Kramer, B.C.3
Jamindar, T.4
Olanow, C.W.5
-
41
-
-
0031886449
-
Deprenyl and desmethylselegiline protect mesencephalic neurons from toxicity induced by glutathione depletion
-
Mytilineou, C., Leonardi, E.K., Radcliffe, P., Heinonen, E.H., Han, S.K., Werner, P., Cohen, G. & Olanow, C.W. (1998) Deprenyl and desmethylselegiline protect mesencephalic neurons from toxicity induced by glutathione depletion. J. Pharmacol. Exp. Ther., 284, 700-706.
-
(1998)
J. Pharmacol. Exp. Ther.
, vol.284
, pp. 700-706
-
-
Mytilineou, C.1
Leonardi, E.K.2
Radcliffe, P.3
Heinonen, E.H.4
Han, S.K.5
Werner, P.6
Cohen, G.7
Olanow, C.W.8
-
42
-
-
0034915764
-
Mechanisms underlying ubiquitination
-
Pickart, C.M. (2001) Mechanisms underlying ubiquitination. Annu. Rev. Biochem., 70, 503-533.
-
(2001)
Annu. Rev. Biochem.
, vol.70
, pp. 503-533
-
-
Pickart, C.M.1
-
43
-
-
0027314026
-
Pathology and biology of the Lewy body
-
Pollanen, M.S., Dickson, D.W. & Bergeron, C. (1993) Pathology and biology of the Lewy body. J. Neuropathol. Exp. Neurol., 52, 183-191.
-
(1993)
J. Neuropathol. Exp. Neurol.
, vol.52
, pp. 183-191
-
-
Pollanen, M.S.1
Dickson, D.W.2
Bergeron, C.3
-
44
-
-
0030744876
-
Mutation in the alpha-synuclein gene identified in families with Parkinson's disease
-
Polymeropoulos, M.H., Lavedan, C., Leroy, E., Ide, S.E., Dehejia, A., Dutra, A., Pike, B., Root, H., Rubenstein, J., Boyer, R., Stenroos, E.S., Chandrasekharappa, S., Athanassiadou, A., Papapetropoulos, T., Johnson, W.G. et al. (1997) Mutation in the alpha-synuclein gene identified in families with Parkinson's disease. Science, 276, 2045-2047.
-
(1997)
Science
, vol.276
, pp. 2045-2047
-
-
Polymeropoulos, M.H.1
Lavedan, C.2
Leroy, E.3
Ide, S.E.4
Dehejia, A.5
Dutra, A.6
Pike, B.7
Root, H.8
Rubenstein, J.9
Boyer, R.10
Stenroos, E.S.11
Chandrasekharappa, S.12
Athanassiadou, A.13
Papapetropoulos, T.14
Johnson, W.G.15
-
45
-
-
0036349463
-
The Mallory body as an aggresome: In vitro studies
-
Riley, N.E., Li, J., Worrall, S., Rothnagel, J.A., Swagell, C., van Leeuwen, F.W. & French, S.W. (2002) The Mallory body as an aggresome: In vitro studies. Exp. Mol. Pathol., 72, 17-23.
-
(2002)
Exp. Mol. Pathol.
, vol.72
, pp. 17-23
-
-
Riley, N.E.1
Li, J.2
Worrall, S.3
Rothnagel, J.A.4
Swagell, C.5
Van Leeuwen, F.W.6
French, S.W.7
-
46
-
-
0025640845
-
Anatomic and disease specificity of NADH CoQ1 reductase (complex I) deficiency in Parkinson's disease
-
Schapira, A.H., Mann, V.M., Cooper, J.M., Dexter, D., Daniel, S.E., Jenner, P., Clark, J.B. & Marsden, C.D. (1990) Anatomic and disease specificity of NADH CoQ1 reductase (complex I) deficiency in Parkinson's disease. J. Neurochem., 55, 2142-2145.
-
(1990)
J. Neurochem.
, vol.55
, pp. 2142-2145
-
-
Schapira, A.H.1
Mann, V.M.2
Cooper, J.M.3
Dexter, D.4
Daniel, S.E.5
Jenner, P.6
Clark, J.B.7
Marsden, C.D.8
-
47
-
-
0036095285
-
Parkin localizes to the lewy bodies of Parkinson disease and dementia with lewy bodies
-
Schlossmacher, M.G., Frosch, M.P., Gai, W.P., Medina, M., Sharma, N., Forno, L., Ochiishi, T., Shimura, H., Sharon, R., Hattori, N., Langston, J.W., Mizuno, Y., Hyman, B.T., Selkoe, D.J. & Kosik, K.S. (2002) Parkin localizes to the lewy bodies of Parkinson disease and dementia with lewy bodies. Am. J. Pathol., 160, 1655-1667.
-
(2002)
Am. J. Pathol.
, vol.160
, pp. 1655-1667
-
-
Schlossmacher, M.G.1
Frosch, M.P.2
Gai, W.P.3
Medina, M.4
Sharma, N.5
Forno, L.6
Ochiishi, T.7
Shimura, H.8
Sharon, R.9
Hattori, N.10
Langston, J.W.11
Mizuno, Y.12
Hyman, B.T.13
Selkoe, D.J.14
Kosik, K.S.15
-
48
-
-
0036132046
-
Occurrence of glutamate receptor subunit 1-containing aggresome-like structures during normal development of rat spinal cord interneurons
-
Serrando, M., Casanovas, A. & Esquerda, J.E. (2002) Occurrence of glutamate receptor subunit 1-containing aggresome-like structures during normal development of rat spinal cord interneurons. J. Comp. Neurol., 442, 23-34.
-
(2002)
J. Comp. Neurol.
, vol.442
, pp. 23-34
-
-
Serrando, M.1
Casanovas, A.2
Esquerda, J.E.3
-
49
-
-
0035139109
-
Cellular defenses against unfolded proteins: A cell biologist thinks about neurodegenerative diseases
-
Sherman, M.Y. & Goldberg, A.L. (2001) Cellular defenses against unfolded proteins: A cell biologist thinks about neurodegenerative diseases. Neuron, 29, 15-32.
-
(2001)
Neuron
, vol.29
, pp. 15-32
-
-
Sherman, M.Y.1
Goldberg, A.L.2
-
50
-
-
0033933048
-
Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase
-
Shimura, H., Hattori, N., Kubo, S., Mizuno, Y., Asakawa, S., Minoshima, S., Shimizu, N., Iwai, K., Chiba, T., Tanaka, K. & Suzuki, T. (2000) Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase. Nature Genet., 25, 302-305.
-
(2000)
Nature Genet.
, vol.25
, pp. 302-305
-
-
Shimura, H.1
Hattori, N.2
Kubo, S.3
Mizuno, Y.4
Asakawa, S.5
Minoshima, S.6
Shimizu, N.7
Iwai, K.8
Chiba, T.9
Tanaka, K.10
Suzuki, T.11
-
51
-
-
0032957883
-
Immunohistochemical and subcellular localization of Parkin protein: Absence of protein in autosomal recessive juvenile parkinsonism patients
-
Shimura, H., Hattori, N., Kubo, S., Yoshikawa, M., Kitada, T., Matsumine, H., Asakawa, S., Minoshima, S., Yamamura, Y., Shimizu, N. & Mizuno, Y. (1999) Immunohistochemical and subcellular localization of Parkin protein: Absence of protein in autosomal recessive juvenile parkinsonism patients. Ann. Neurol., 45, 668-672.
-
(1999)
Ann. Neurol.
, vol.45
, pp. 668-672
-
-
Shimura, H.1
Hattori, N.2
Kubo, S.3
Yoshikawa, M.4
Kitada, T.5
Matsumine, H.6
Asakawa, S.7
Minoshima, S.8
Yamamura, Y.9
Shimizu, N.10
Mizuno, Y.11
-
52
-
-
0035854437
-
Ubiquitination of a new form of {alpha}-synuclein by parkin from human brain: Implications for Parkinson's disease
-
Shimura, H., Schlossmacher, M.G., Hattori, N., Frosch, M.P., Trockenbacher, A., Schneider, R., Mizuno, Y., Kosik, K.S. & Selkoe, D.J. (2001) Ubiquitination of a new form of {alpha}-synuclein by parkin from human brain: Implications for Parkinson's disease. Science, 293, 263-269.
-
(2001)
Science
, vol.293
, pp. 263-269
-
-
Shimura, H.1
Schlossmacher, M.G.2
Hattori, N.3
Frosch, M.P.4
Trockenbacher, A.5
Schneider, R.6
Mizuno, Y.7
Kosik, K.S.8
Selkoe, D.J.9
-
53
-
-
0037177250
-
Jr (2002) Molecular crowding accelerates fibrillization of alpha-synuclein: Could an increase in the cytoplasmic protein concentration induce Parkinson's disease?
-
Shtilerman, M.D., Ding, T.T. & Lansbury, P.T. Jr (2002) Molecular crowding accelerates fibrillization of alpha-synuclein: Could an increase in the cytoplasmic protein concentration induce Parkinson's disease? Biochemistry, 41, 3855-3860.
-
Biochemistry
, vol.41
, pp. 3855-3860
-
-
Shtilerman, M.D.1
Ding, T.T.2
Lansbury, P.T.3
-
54
-
-
0032568534
-
alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies
-
Spillantini, M.G., Crowther, R.A., Jakes, R., Hasegawa, M. & Goedert, M. (1998) alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies. Proc. Natl Acad. Sci. USA, 95, 6469-6473.
-
(1998)
Proc. Natl Acad. Sci. USA
, vol.95
, pp. 6469-6473
-
-
Spillantini, M.G.1
Crowther, R.A.2
Jakes, R.3
Hasegawa, M.4
Goedert, M.5
-
55
-
-
0025849047
-
Gamma-tubulin is a highly conserved component of the centrosome
-
Stearns, T., Evans, L. & Kirschner, M. (1991) Gamma-tubulin is a highly conserved component of the centrosome. Cell, 65, 825-836.
-
(1991)
Cell
, vol.65
, pp. 825-836
-
-
Stearns, T.1
Evans, L.2
Kirschner, M.3
-
56
-
-
0035976835
-
alpha-Synuclein metabolism and aggregation is linged to ubiqutin-independent degradation by the proteasome
-
25504
-
Tofaris, G.K., Layfield, R. & Spillantini, M.G. (2001) alpha-Synuclein metabolism and aggregation is linged to ubiqutin-independent degradation by the proteasome. FEBS Lett., 25504, 1-5.
-
(2001)
FEBS Lett.
, pp. 1-5
-
-
Tofaris, G.K.1
Layfield, R.2
Spillantini, M.G.3
-
57
-
-
0035824651
-
Sensitivity of mammalian cells expressing mutant ubiquitin to protein damaging agents
-
Tsirigotis, M., Zhang, M., Chiu, R.K., Wouters, B.G. & Gray, D.A. (2001) Sensitivity of mammalian cells expressing mutant ubiquitin to protein damaging agents. J. Biol. Chem, 276, 46073-46078.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 46073-46078
-
-
Tsirigotis, M.1
Zhang, M.2
Chiu, R.K.3
Wouters, B.G.4
Gray, D.A.5
-
58
-
-
0037181497
-
Accelerated alpha-synuclein fibrillation in crowded milieu
-
Uversky, V.N.E.M.C., Bower, K.S., Li, J. & Fink, A.L. (2002) Accelerated alpha-synuclein fibrillation in crowded milieu. FEBS Lett., 515, 99-103.
-
(2002)
FEBS Lett.
, vol.515
, pp. 99-103
-
-
Uversky, V.N.E.M.C.1
Bower, K.S.2
Li, J.3
Fink, A.L.4
-
59
-
-
0032867676
-
The 26S proteasome: A molecular machine designed for controlled proteolysis
-
Voges, D., Zwickl, P. & Baumeister, W. (1999) The 26S proteasome: A molecular machine designed for controlled proteolysis. Annu. Rev. Biochem., 68, 1015-1068.
-
(1999)
Annu. Rev. Biochem.
, vol.68
, pp. 1015-1068
-
-
Voges, D.1
Zwickl, P.2
Baumeister, W.3
-
60
-
-
0034754875
-
Accumulation of mutant huntingtin fragments in aggresome-like inclusion bodies as a result of insufficient protein degradation
-
Waelter, S., Boeddrich, A., Lurz, R., Scherzinger, E., Lueder, G., Lehrach, H. & Wanker, E.E. (2001) Accumulation of mutant huntingtin fragments in aggresome-like inclusion bodies as a result of insufficient protein degradation. Mol. Biol. Cell, 12, 1393-1407.
-
(2001)
Mol. Biol. Cell
, vol.12
, pp. 1393-1407
-
-
Waelter, S.1
Boeddrich, A.2
Lurz, R.3
Scherzinger, E.4
Lueder, G.5
Lehrach, H.6
Wanker, E.E.7
-
61
-
-
0345593387
-
Dynamic association of proteasomal machinery with the centrosome
-
Wigley, W.C., Fabunmi, R.P., Lee, M.G., Marino, C.R., Muallem, S., DeMartino, G.N. & Thomas, P.J. (1999) Dynamic association of proteasomal machinery with the centrosome. J. Cell Biol., 145, 481-490.
-
(1999)
J. Cell Biol.
, vol.145
, pp. 481-490
-
-
Wigley, W.C.1
Fabunmi, R.P.2
Lee, M.G.3
Marino, C.R.4
Muallem, S.5
DeMartino, G.N.6
Thomas, P.J.7
-
62
-
-
0029917194
-
Immunohistochemical detection of 4-hydroxynonenal protein adducts in Parkinson disease
-
Yoritaka, A., Hattori, N., Uchida, K., Tanaka, M., Stadtman, E.R. & Mizuno, Y. (1996) Immunohistochemical detection of 4-hydroxynonenal protein adducts in Parkinson disease. Proc. Natl Acad. Sci. USA, 93, 2696-2701.
-
(1996)
Proc. Natl Acad. Sci. USA
, vol.93
, pp. 2696-2701
-
-
Yoritaka, A.1
Hattori, N.2
Uchida, K.3
Tanaka, M.4
Stadtman, E.R.5
Mizuno, Y.6
-
63
-
-
0031662791
-
The Golgi apparatus and the centrosome are localized to the sites of newly emerging axons in cerebellar granule neurons in vitro
-
Zmuda, J.F. & Rivas, R.J. (1998) The Golgi apparatus and the centrosome are localized to the sites of newly emerging axons in cerebellar granule neurons in vitro. Cell Motil. Cytoskeleton, 41, 18-38.
-
(1998)
Cell Motil. Cytoskeleton
, vol.41
, pp. 18-38
-
-
Zmuda, J.F.1
Rivas, R.J.2
|