-
1
-
-
0028103819
-
Inflammatory mechanisms in Alzheimer's disease: Implications for therapy
-
Aisen PS, Davis KL. 1994. Inflammatory mechanisms in Alzheimer's disease: implications for therapy. Am J Psychiatry 151:1105-1113.
-
(1994)
Am J Psychiatry
, vol.151
, pp. 1105-1113
-
-
Aisen, P.S.1
Davis, K.L.2
-
2
-
-
0030998896
-
The search for disease-modifying treatment for Alzheimer's disease
-
Aisen PS, Davis KL. 1997. The search for disease-modifying treatment for Alzheimer's disease. Neurology 48(Suppl 6):S35-S41.
-
(1997)
Neurology
, vol.48
, Issue.SUPPL. 6
-
-
Aisen, P.S.1
Davis, K.L.2
-
3
-
-
0031973405
-
Glucocorticoid in Alzheimer's disease: The story so far
-
Aisen PS, Pasinetti GM. 1998. Glucocorticoid in Alzheimer's disease: the story so far. Drugs Aging 12:1-6.
-
(1998)
Drugs Aging
, vol.12
, pp. 1-6
-
-
Aisen, P.S.1
Pasinetti, G.M.2
-
4
-
-
0029145084
-
Are reactive oxygen species involved in Alzheimer's disease?
-
Benzi G, Moretti A. 1995. Are reactive oxygen species involved in Alzheimer's disease? Neurobiol Aging 16:661-674.
-
(1995)
Neurobiol Aging
, vol.16
, pp. 661-674
-
-
Benzi, G.1
Moretti, A.2
-
5
-
-
0029866991
-
β-Amyloid toxicity in organotypic hippocampal cultures: Protection by EUK-8, a synthetic catalytic free radical scavenger
-
Bruce AJ, Malfroy B, Baudry M. 1996. β-Amyloid toxicity in organotypic hippocampal cultures: protection by EUK-8, a synthetic catalytic free radical scavenger. Proc Natl Acad Sci USA 93:2312-2316.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 2312-2316
-
-
Bruce, A.J.1
Malfroy, B.2
Baudry, M.3
-
7
-
-
0029762276
-
Reactive oxygen species as causal agents in the neurotoxicity of the Alzheimer's disease-associated amyloid beta peptide
-
Henley K, Butterfield DA, Hall N, Cole P, Subramaniam R, Mark R, Mattson MP, Markesbery WR, Harris ME, Aksenov M, Aksenova M, Wu JF, Carney JM. 1996. Reactive oxygen species as causal agents in the neurotoxicity of the Alzheimer's disease-associated amyloid beta peptide. Ann NY Acad Sci 786:120-134.
-
(1996)
Ann NY Acad Sci
, vol.786
, pp. 120-134
-
-
Henley, K.1
Butterfield, D.A.2
Hall, N.3
Cole, P.4
Subramaniam, R.5
Mark, R.6
Mattson, M.P.7
Markesbery, W.R.8
Harris, M.E.9
Aksenov, M.10
Aksenova, M.11
Wu, J.F.12
Carney, J.M.13
-
8
-
-
0000582873
-
COX-2 contributes to NMDA-induced neuronal death in cortical cell cultures
-
Hewett SJ, Hewett JA. 1997. COX-2 contributes to NMDA-induced neuronal death in cortical cell cultures. Soc Neurosci Abstr 23:1666.
-
(1997)
Soc Neurosci Abstr
, vol.23
, pp. 1666
-
-
Hewett, S.J.1
Hewett, J.A.2
-
9
-
-
0344468649
-
Transgenic mice with neuronal overexpression of human cyclooxygenase-2: A model of Alzheimer's disease neurodegeneration
-
Ho L, Kelley K, Blanco C, Aisen PS, Pasinetti GM. 1998a. Transgenic mice with neuronal overexpression of human cyclooxygenase-2: a model of Alzheimer's disease neurodegeneration [abstract]. Soc Neurosci Abstr 24:727.
-
(1998)
Soc Neurosci Abstr
, vol.24
, pp. 727
-
-
Ho, L.1
Kelley, K.2
Blanco, C.3
Aisen, P.S.4
Pasinetti, G.M.5
-
10
-
-
0032516792
-
Induction of cyclooxygenase (COX)-2 but not COX-1 gene expression in apoptotic cell death
-
Ho L, Osaka H, Aisen PS, Pasinetti GM. 1998b. Induction of cyclooxygenase (COX)-2 but not COX-1 gene expression in apoptotic cell death. J Neuroimmunol 89:142-149.
-
(1998)
J Neuroimmunol
, vol.89
, pp. 142-149
-
-
Ho, L.1
Osaka, H.2
Aisen, P.S.3
Pasinetti, G.M.4
-
11
-
-
0029995029
-
COX-2, a synaptically induced enzyme, is expressed by excitatory neurons at postsynaptic sites in rat cerebral cortex
-
Kaufmann WE, Worley PF, Pegg J, Bremer M, Isakson P. 1996. COX-2, a synaptically induced enzyme, is expressed by excitatory neurons at postsynaptic sites in rat cerebral cortex. Proc Natl Acad Sci USA 93:2317-2321.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 2317-2321
-
-
Kaufmann, W.E.1
Worley, P.F.2
Pegg, J.3
Bremer, M.4
Isakson, P.5
-
12
-
-
0345331416
-
-
in press
-
Kelley K, Ho L, Winger D, Freire-Moar J, Aisen PS, Pasinetti GM. 1999. Potentiation of excitotoxicity in transgenic mice overexpressing neuronal cyclooxygenase-2 (in press).
-
(1999)
Potentiation of Excitotoxicity in Transgenic Mice Overexpressing Neuronal Cyclooxygenase-2
-
-
Kelley, K.1
Ho, L.2
Winger, D.3
Freire-Moar, J.4
Aisen, P.S.5
Pasinetti, G.M.6
-
13
-
-
0022414054
-
Diagnosis of Alzheimer's disease
-
Khachaturian ZS. 1985. Diagnosis of Alzheimer's disease. Arch Neurol 42:1097-1105.
-
(1985)
Arch Neurol
, vol.42
, pp. 1097-1105
-
-
Khachaturian, Z.S.1
-
14
-
-
0033608169
-
Increased expression of cyclooxygenases and peroxisome proliferator-activated receptor-γ in Alzheimer's disease brains
-
Kitamura Y, Shimohama S, Koike H, Kakimura J, Matsuoka Y, Nomura Y, Gebicke-Haerter P, Taniguchi T. 1999. Increased expression of cyclooxygenases and peroxisome proliferator-activated receptor-γ in Alzheimer's disease brains. Biochem Biophys Res Commun 254:582-586.
-
(1999)
Biochem Biophys Res Commun
, vol.254
, pp. 582-586
-
-
Kitamura, Y.1
Shimohama, S.2
Koike, H.3
Kakimura, J.4
Matsuoka, Y.5
Nomura, Y.6
Gebicke-Haerter, P.7
Taniguchi, T.8
-
15
-
-
0001273527
-
Regional localization of cells containing complement C1q and C4 mRNAs in the frontal cortex during Alzheimer's disease
-
Lampert-Etchells M, Pasinetti GM, Finch CE, Johnson SA. 1993. Regional localization of cells containing complement C1q and C4 mRNAs in the frontal cortex during Alzheimer's disease. Neurodegeneration 2:111-121.
-
(1993)
Neurodegeneration
, vol.2
, pp. 111-121
-
-
Lampert-Etchells, M.1
Pasinetti, G.M.2
Finch, C.E.3
Johnson, S.A.4
-
16
-
-
0031900411
-
Nonsteroidal anti-inflammatory drug use and Alzheimer-type pathology in aging
-
Mackenzie IRA, Munoz DG. 1998. Nonsteroidal anti-inflammatory drug use and Alzheimer-type pathology in aging. Neurology 50:986-990.
-
(1998)
Neurology
, vol.50
, pp. 986-990
-
-
Mackenzie, I.R.A.1
Munoz, D.G.2
-
17
-
-
0029811901
-
Arthritis and anti-inflammatory agents as possible protective factors for Alzheimer's disease: A review of 17 epidemiologic studies
-
McGeer PL, Schulzer M, McGeer EG. 1996. Arthritis and anti-inflammatory agents as possible protective factors for Alzheimer's disease: a review of 17 epidemiologic studies. Neurology 47:425-432.
-
(1996)
Neurology
, vol.47
, pp. 425-432
-
-
McGeer, P.L.1
Schulzer, M.2
McGeer, E.G.3
-
18
-
-
0022178992
-
Morphometric investigation of nerve cells, neuropil and senile plaques in senile dementia of the Alzheimer type
-
Meier-Ruge W, Ulrich J, Stahelin HB. 1985. Morphometric investigation of nerve cells, neuropil and senile plaques in senile dementia of the Alzheimer type. Arch Gerontol Geriatr 4:219-229.
-
(1985)
Arch Gerontol Geriatr
, vol.4
, pp. 219-229
-
-
Meier-Ruge, W.1
Ulrich, J.2
Stahelin, H.B.3
-
19
-
-
0030700593
-
The CERAD neuropathology protocol and consensus recommendations for the postmortem diagnosis of Alzheimer's disease: A commentary
-
Mirra SS. 1997. The CERAD neuropathology protocol and consensus recommendations for the postmortem diagnosis of Alzheimer's disease: a commentary. Neurobiol Aging 18(Suppl):S91-S94
-
(1997)
Neurobiol Aging
, vol.18
, Issue.SUPPL.
-
-
Mirra, S.S.1
-
20
-
-
0030951257
-
Induction of cyclo-oxygenase 2 in brains of patients with Down's syndrome and dementia of Alzheimer type: Specific localization in affected neurones and axons
-
Oka A, Takashima S. 1997. Induction of cyclo-oxygenase 2 in brains of patients with Down's syndrome and dementia of Alzheimer type: specific localization in affected neurones and axons. NeuroReport 8:1161-1164.
-
(1997)
NeuroReport
, vol.8
, pp. 1161-1164
-
-
Oka, A.1
Takashima, S.2
-
21
-
-
0032190264
-
Cyclooxygenase and inflammation in Alzheimer's disease: Experimental approaches and clinical interventions
-
Pasinetti GM. 1998. Cyclooxygenase and inflammation in Alzheimer's disease: experimental approaches and clinical interventions. J Neurosci Res 54:1-6.
-
(1998)
J Neurosci Res
, vol.54
, pp. 1-6
-
-
Pasinetti, G.M.1
-
22
-
-
0032551633
-
Cyclooxygenase-2 expression is increased in frontal cortex of Alzheimer's disease brain
-
Pasinetti GM, Aisen PS. 1998. Cyclooxygenase-2 expression is increased in frontal cortex of Alzheimer's disease brain. Neuroscience 87:319-324.
-
(1998)
Neuroscience
, vol.87
, pp. 319-324
-
-
Pasinetti, G.M.1
Aisen, P.S.2
-
23
-
-
0030924506
-
Beta-amyloid neurotoxicity in vitro: Evidence of oxidative stress but not protection by antioxidants
-
Pike CJ, Ramezan-Arab N, Cotman CW. 1997. Beta-amyloid neurotoxicity in vitro: evidence of oxidative stress but not protection by antioxidants. J Neurochem 69:1601-1611.
-
(1997)
J Neurochem
, vol.69
, pp. 1601-1611
-
-
Pike, C.J.1
Ramezan-Arab, N.2
Cotman, C.W.3
-
24
-
-
0022401271
-
Quantitative morphology and regional and laminar distribution of senile plaques in Alzheimer's disease
-
Rogers J, Morrison JH. 1985. Quantitative morphology and regional and laminar distribution of senile plaques in Alzheimer's disease. J Neurosci 5:2801-2808.
-
(1985)
J Neurosci
, vol.5
, pp. 2801-2808
-
-
Rogers, J.1
Morrison, J.H.2
-
25
-
-
0027268393
-
Clinical trial of indomethacin in Alzheimer's disease
-
Rogers J, Kirby LC, Hempelman SR, Berry DL, McGeer PL, Kaszniak AW, Zalinski J, Cofield M, Mansukhani L, Willson P, Kogan F. 1993. Clinical trial of indomethacin in Alzheimer's disease. Neurology 43:1609-1611.
-
(1993)
Neurology
, vol.43
, pp. 1609-1611
-
-
Rogers, J.1
Kirby, L.C.2
Hempelman, S.R.3
Berry, D.L.4
McGeer, P.L.5
Kaszniak, A.W.6
Zalinski, J.7
Cofield, M.8
Mansukhani, L.9
Willson, P.10
Kogan, F.11
-
26
-
-
0028118846
-
Inhibition of PC12 cell redox activity is a specific, early indicator of the mechanism of β-amyloid-mediated cell death
-
Shearman MS, Ragan CI, Iversen LL. 1994. Inhibition of PC12 cell redox activity is a specific, early indicator of the mechanism of β-amyloid-mediated cell death. Proc Natl Acad Sci USA 91:1470-1474.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 1470-1474
-
-
Shearman, M.S.1
Ragan, C.I.2
Iversen, L.L.3
-
27
-
-
0031127741
-
Maturational regulation and regional induction of cyclooxygenase-2 in rat brain: Implications for Alzheimer's disease
-
Tocco G, Freire O, Schreiber SS, Sakhi SH, Aisen PS, Pasinetti GM. 1997. Maturational regulation and regional induction of cyclooxygenase-2 in rat brain: implications for Alzheimer's disease. Exp Neurol 144:339-349.
-
(1997)
Exp Neurol
, vol.144
, pp. 339-349
-
-
Tocco, G.1
Freire, O.2
Schreiber, S.S.3
Sakhi, S.H.4
Aisen, P.S.5
Pasinetti, G.M.6
-
28
-
-
0028926813
-
New insights into the mode of action of anti-inflammatory drugs
-
Vane JR, Botting RM. 1995. New insights into the mode of action of anti-inflammatory drugs. Inflam Res 44:1-10.
-
(1995)
Inflam Res
, vol.44
, pp. 1-10
-
-
Vane, J.R.1
Botting, R.M.2
-
29
-
-
0027290813
-
Expression of a mitogen-inducible cyclooxygenase in brain neurons: Regulation by synaptic activity and glucocorticoids
-
Yamagata K, Andreasson KI, Kaufmann WE, Barnes CA, Worley PF. 1993. Expression of a mitogen-inducible cyclooxygenase in brain neurons: regulation by synaptic activity and glucocorticoids. Neuron 11:371-386.
-
(1993)
Neuron
, vol.11
, pp. 371-386
-
-
Yamagata, K.1
Andreasson, K.I.2
Kaufmann, W.E.3
Barnes, C.A.4
Worley, P.F.5
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