-
1
-
-
0028227203
-
Analysis of somatic mutation in five B cell subsets of human tonsil
-
Pascual V, Liu YL, Magalski A, de Bouteiller O, Banchereau J, Copra JD: Analysis of somatic mutation in five B cell subsets of human tonsil. J Exp Med 180:329-339, 1994
-
(1994)
J Exp Med
, vol.180
, pp. 329-339
-
-
Pascual, V.1
Liu, Y.L.2
Magalski, A.3
De Bouteiller, O.4
Banchereau, J.5
Copra, J.D.6
-
2
-
-
0029059370
-
Soluble antigen can cause enhanced apoptosis of germinal-centre B cells
-
Pulendran B, Kannourakis G, Nouri S, Smith KG, Nossal GJ: Soluble antigen can cause enhanced apoptosis of germinal-centre B cells. Nature 375:331-334, 1995
-
(1995)
Nature
, vol.375
, pp. 331-334
-
-
Pulendran, B.1
Kannourakis, G.2
Nouri, S.3
Smith, K.G.4
Nossal, G.J.5
-
4
-
-
0031956666
-
Receptor editing and commitment in B lymphocytes
-
Hertz M, Nemazee D: Receptor editing and commitment in B lymphocytes. Curr Opin Immunol 10:208-213, 1998
-
(1998)
Curr Opin Immunol
, vol.10
, pp. 208-213
-
-
Hertz, M.1
Nemazee, D.2
-
6
-
-
0031252393
-
In vitro triggering of somatic mutation in human naive B cells
-
Razanajaona D, Denepoux S, Blanchard D, de Bouteiller O, Liu YJ, Banchereau J, Lebecque S: In vitro triggering of somatic mutation in human naive B cells. J Immunol 159:3347-3353, 1997
-
(1997)
J Immunol
, vol.159
, pp. 3347-3353
-
-
Razanajaona, D.1
Denepoux, S.2
Blanchard, D.3
De Bouteiller, O.4
Liu, Y.J.5
Banchereau, J.6
Lebecque, S.7
-
7
-
-
0343417077
-
Induction of somatic mutation in a human B cell line in vitro
-
Denepoux S, Razanajaona D, Blanchard D, Meffre G, Capra JD, Banchereau J, Lebecque S: Induction of somatic mutation in a human B cell line in vitro. Immunity 6:35-46, 1997
-
(1997)
Immunity
, vol.6
, pp. 35-46
-
-
Denepoux, S.1
Razanajaona, D.2
Blanchard, D.3
Meffre, G.4
Capra, J.D.5
Banchereau, J.6
Lebecque, S.7
-
9
-
-
0028961269
-
Defining subsets of naive and memory B cells based on the ability of their progeny to somatically mutate in vitro
-
Decker DJ, Linton PJ, Zaharevitz S, Biery M, Gingeras TR, Klinman NR: Defining subsets of naive and memory B cells based on the ability of their progeny to somatically mutate in vitro. Immunity 2:195-203, 1995
-
(1995)
Immunity
, vol.2
, pp. 195-203
-
-
Decker, D.J.1
Linton, P.J.2
Zaharevitz, S.3
Biery, M.4
Gingeras, T.R.5
Klinman, N.R.6
-
10
-
-
0032032241
-
+B cell line
-
+B cell line. J Immunol 160:2145-2157, 1998
-
(1998)
J Immunol
, vol.160
, pp. 2145-2157
-
-
Cerutti, A.1
Zan, H.2
Schaffer, A.3
Bergsagel, L.4
Harindranath, N.5
Max, E.E.6
Casali, P.7
-
11
-
-
0032534070
-
CD40 engagement triggers switching to IgA1 and IgA2 in human B cells through induction of endogenous TGF-β: Evidence for TGF-β but not IL-10-dependent direct S μ→S α and sequential S μ→S γ, S γ→ S α DNA recombination
-
Zan H. Cerutti A, Dramitinos P, Schaffer A, Casali P: CD40 engagement triggers switching to IgA1 and IgA2 in human B cells through induction of endogenous TGF-β: Evidence for TGF-β but not IL-10-dependent direct S μ→S α and sequential S μ→S γ, S γ→ S α DNA recombination. J Immunol 161:5217-5225, 1998
-
(1998)
J Immunol
, vol.161
, pp. 5217-5225
-
-
Zan, H.1
Cerutti, A.2
Dramitinos, P.3
Schaffer, A.4
Casali, P.5
-
12
-
-
0032142893
-
CD30 is a CD40-inducible molecule that negatively regulates CD40-mediated immunoglobulin class switching in non-antigen-selected human B cells
-
Cerutti A, Schaffer A, Shah S, Zan H, Liou HC, Goodwin RG, Casali P: CD30 is a CD40-inducible molecule that negatively regulates CD40-mediated immunoglobulin class switching in non-antigen-selected human B cells. Immunity 9:247-256, 1998
-
(1998)
Immunity
, vol.9
, pp. 247-256
-
-
Cerutti, A.1
Schaffer, A.2
Shah, S.3
Zan, H.4
Liou, H.C.5
Goodwin, R.G.6
Casali, P.7
-
13
-
-
0033136276
-
The evolutionarily conserved sequence upstream of the human Ig heavy chain S γ 3 region is an inducible promoter: Synergistic activation by CD40 ligand and IL-4 via cooperative NF-κ B and STAT- 6 binding sites
-
Schaffer A, Cerutti A, Shah S, Zan H, Casali P: The evolutionarily conserved sequence upstream of the human Ig heavy chain S γ 3 region is an inducible promoter: Synergistic activation by CD40 ligand and IL-4 via cooperative NF-κ B and STAT-6 binding sites. J Immunol 162:5327-5336, 1999
-
(1999)
J Immunol
, vol.162
, pp. 5327-5336
-
-
Schaffer, A.1
Cerutti, A.2
Shah, S.3
Zan, H.4
Casali, P.5
-
14
-
-
0038157392
-
Selective inhibition of class switching to IgG and IgE by recruitment of the HoxC4 and Oct-1 homeodomain proteins and Ku70/Ku86 to newly identified ATTT cis-elements
-
in press
-
Schaffer A, Kim EC, Wu X, Zan H, Testoni L, Salamon S, Cerutti A, Casali P: Selective inhibition of class switching to IgG and IgE by recruitment of the HoxC4 and Oct-1 homeodomain proteins and Ku70/Ku86 to newly identified ATTT cis-elements. J Biol Chem in press
-
J Biol Chem
-
-
Schaffer, A.1
Kim, E.C.2
Wu, X.3
Zan, H.4
Testoni, L.5
Salamon, S.6
Cerutti, A.7
Casali, P.8
-
15
-
-
0034661695
-
+B cells
-
+B cells. J Immunol 165:786-794, 2000
-
(2000)
J Immunol
, vol.165
, pp. 786-794
-
-
Cerutti, A.1
Schaffer, A.2
Goodwin, R.G.3
Shah, S.4
Zan, H.5
Ely, S.6
Casali, P.7
-
16
-
-
0034662044
-
B cell receptor engagement and T cell contact induce Bcl-6 somatic hypermutation in human B cells: Identity with Ig hypermutation
-
Zan H, Li Z, Yamaji K, Dramitinos P, Cerutti A, Casali P: B cell receptor engagement and T cell contact induce Bcl-6 somatic hypermutation in human B cells: Identity with Ig hypermutation. J Immunol 165:830-839, 2000
-
(2000)
J Immunol
, vol.165
, pp. 830-839
-
-
Zan, H.1
Li, Z.2
Yamaji, K.3
Dramitinos, P.4
Cerutti, A.5
Casali, P.6
-
17
-
-
2642623612
-
Mutation of BCL-6 gene in normal B cells by the process of somatic hypermutation of Ig genes
-
Shen HM, Peters A, Baron B, Zhu X, Storb U: Mutation of BCL-6 gene in normal B cells by the process of somatic hypermutation of Ig genes. Science 280:1750-1752, 1998
-
(1998)
Science
, vol.280
, pp. 1750-1752
-
-
Shen, H.M.1
Peters, A.2
Baron, B.3
Zhu, X.4
Storb, U.5
-
18
-
-
0029614378
-
Frequent somatic hypermutation of the 5′ noncoding region of the BCL-6 gene in B-cell lymphoma
-
Migliazza A, Martinotti S, Chen W, Fusco C, Ye BH, Knowles DM, Offit K, Chaganti RS, Dalla-Favera R: Frequent somatic hypermutation of the 5′ noncoding region of the BCL-6 gene in B-cell lymphoma. Proc Natl Acad Sci USA 92:12520-12524, 1995
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 12520-12524
-
-
Migliazza, A.1
Martinotti, S.2
Chen, W.3
Fusco, C.4
Ye, B.H.5
Knowles, D.M.6
Offit, K.7
Chaganti, R.S.8
Dalla-Favera, R.9
-
19
-
-
0029087972
-
IL-4 plus CD40 monoclonal antibody induces human B cells γ subclass-specific isotype switch: Switching to γ 1, γ 3, and γ 4, but not gamma 2
-
Fujieda S, Zhang K, Saxon A: IL-4 plus CD40 monoclonal antibody induces human B cells γ subclass-specific isotype switch: Switching to γ 1, γ 3, and γ 4, but not gamma 2. J Immunol 155:2318-2328, 1995
-
(1995)
J Immunol
, vol.155
, pp. 2318-2328
-
-
Fujieda, S.1
Zhang, K.2
Saxon, A.3
-
20
-
-
0029917122
-
Interleukin-10 induces immunoglobulin G isotype switch recombination in human CD40-activated naive B lymphocytes
-
Malisan F, Briere F, Bridon JM, Harindranath N, Mills FC, Max EE, Banchereau J, Martinez-Valdez H: Interleukin-10 induces immunoglobulin G isotype switch recombination in human CD40-activated naive B lymphocytes. J. Exp Med 183:937-947, 1996
-
(1996)
J. Exp Med
, vol.183
, pp. 937-947
-
-
Malisan, F.1
Briere, F.2
Bridon, J.M.3
Harindranath, N.4
Mills, F.C.5
Max, E.E.6
Banchereau, J.7
Martinez-Valdez, H.8
-
21
-
-
0034268780
-
Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme
-
Muramatsu M, Kinoshita K, Fagarasan S, Yamada S, Shinkai Y, Honjo T: Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme. Cell 102:553-563, 2000
-
(2000)
Cell
, vol.102
, pp. 553-563
-
-
Muramatsu, M.1
Kinoshita, K.2
Fagarasan, S.3
Yamada, S.4
Shinkai, Y.5
Honjo, T.6
-
22
-
-
0034264851
-
Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper IgM syndrome (HIGM2)
-
Revy P, Muto T, Levy Y, Geissmann F, Plebani A, Sanal O, Catalan N, Forveille M, Dufourcq-Labelouse R, Gennery A, Tezcan I, Ersoy F, Kayserili H, Ugazio AG, Brousse N, Muramatsu M, Notarangelo LD, Kinoshita K, Honjo T, Fischer A, Durandy A: Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper IgM syndrome (HIGM2). Cell 102:565-575, 2000
-
(2000)
Cell
, vol.102
, pp. 565-575
-
-
Revy, P.1
Muto, T.2
Levy, Y.3
Geissmann, F.4
Plebani, A.5
Sanal, O.6
Catalan, N.7
Forveille, M.8
Dufourcq-Labelouse, R.9
Gennery, A.10
Tezcan, I.11
Ersoy, F.12
Kayserili, H.13
Ugazio, A.G.14
Brousse, N.15
Muramatsu, M.16
Notarangelo, L.D.17
Kinoshita, K.18
Honjo, T.19
Fischer, A.20
Durandy, A.21
more..
-
23
-
-
0031944788
-
Recombination-based mechanisms for somatic hypermutation
-
Kong Q, Harris RS, Maizels N: Recombination-based mechanisms for somatic hypermutation. Immunol Rev 162:67-76, 1998
-
(1998)
Immunol Rev
, vol.162
, pp. 67-76
-
-
Kong, Q.1
Harris, R.S.2
Maizels, N.3
-
24
-
-
0036234455
-
Somatic hypermutation of immunoglobulin genes: Merging mechanisms for genetic diversity
-
Papavasiliou FN, Schatz DG: Somatic hypermutation of immunoglobulin genes: Merging mechanisms for genetic diversity. Cell 109 (Suppl) S35-S44, 2002
-
(2002)
Cell
, vol.109
, Issue.SUPPL.
-
-
Papavasiliou, F.N.1
Schatz, D.G.2
-
25
-
-
0036533341
-
Somatic immunoglobulin hypermutation
-
Diaz M, Casali P: Somatic immunoglobulin hypermutation. Curr Opin Immunol 14:235-240, 2002
-
(2002)
Curr Opin Immunol
, vol.14
, pp. 235-240
-
-
Diaz, M.1
Casali, P.2
-
27
-
-
0025630537
-
Boundaries of somatic mutation in rearranged immunoglobulin genes: 5′ boundary is near the promoter, and 3′ boundary is approximately 1 kb from V(D)J gene
-
Lebecque SG, Gearhart PJ: Boundaries of somatic mutation in rearranged immunoglobulin genes: 5′ boundary is near the promoter, and 3′ boundary is approximately 1 kb from V(D)J gene. J Exp Med 172:1717-1727, 1990
-
(1990)
J Exp Med
, vol.172
, pp. 1717-1727
-
-
Lebecque, S.G.1
Gearhart, P.J.2
-
28
-
-
0028125606
-
Mapping the upstream boundary of somatic mutations in rearranged immunoglobulin transgenes and endogenous genes
-
Rogerson BJ: Mapping the upstream boundary of somatic mutations in rearranged immunoglobulin transgenes and endogenous genes. Mol Immunol 31:83-98, 1994
-
(1994)
Mol Immunol
, vol.31
, pp. 83-98
-
-
Rogerson, B.J.1
-
29
-
-
0028243803
-
The 5′ boundary of somatic hypermutation in a V κ gene is in the leader intron
-
Rada C, Gonzalez-Fernandez A, Jarvis JM, Milstein C: The 5′ boundary of somatic hypermutation in a V κ gene is in the leader intron. Eur J Immunol 24:1453-1457, 1994
-
(1994)
Eur J Immunol
, vol.24
, pp. 1453-1457
-
-
Rada, C.1
Gonzalez-Fernandez, A.2
Jarvis, J.M.3
Milstein, C.4
-
30
-
-
0030063726
-
Somatic hypermutation of immunoglobulin genes is linked to transcription initiation
-
Peters A, Storb U: Somatic hypermutation of immunoglobulin genes is linked to transcription initiation. Immunity 4:57-65, 1996
-
(1996)
Immunity
, vol.4
, pp. 57-65
-
-
Peters, A.1
Storb, U.2
-
31
-
-
0032127810
-
Somatic hypermutation in the heavy chain locus correlates with transcription
-
Fukita Y, Jacobs H, Rajewsky K: Somatic hypermutation in the heavy chain locus correlates with transcription. Immunity 9:105-114, 1998
-
(1998)
Immunity
, vol.9
, pp. 105-114
-
-
Fukita, Y.1
Jacobs, H.2
Rajewsky, K.3
-
32
-
-
0035966393
-
Transcription, β-like DNA polymerases and hypermutation
-
Reynaud CA, Frey S, Aoufouchi S, Faili A, Bertocci B, Dahan A, Flatter E, Delbos F, Storck S, Zober C, Weill JC: Transcription, β-like DNA polymerases and hypermutation. Philos Trans R Soc Lond B Biol Sci 356:91-97, 2001
-
(2001)
Philos Trans R Soc Lond B Biol Sci
, vol.356
, pp. 91-97
-
-
Reynaud, C.A.1
Frey, S.2
Aoufouchi, S.3
Faili, A.4
Bertocci, B.5
Dahan, A.6
Flatter, E.7
Delbos, F.8
Storck, S.9
Zober, C.10
Weill, J.C.11
-
33
-
-
0026443954
-
Somatic hypermutagenesis in immunoglobulin genes. II. Influence of neighbouring base sequences on mutagenesis
-
Rogozin IB, Kolchanov NA: Somatic hypermutagenesis in immunoglobulin genes. II. Influence of neighbouring base sequences on mutagenesis. Biochim Biophys Acta 1171:11-18, 1992
-
(1992)
Biochim Biophys Acta
, vol.1171
, pp. 11-18
-
-
Rogozin, I.B.1
Kolchanov, N.A.2
-
34
-
-
0032585719
-
Somatic hypermutation of VκJκ rearrangements: Targeting of RGYW motifs on both DNA strands and preferential selection of mutated codons within RGYW motifs
-
Foster SJ, Dorner T, Lipsky PE: Somatic hypermutation of VκJκ rearrangements: Targeting of RGYW motifs on both DNA strands and preferential selection of mutated codons within RGYW motifs. Eur J Immunol 29:4011-4021, 1999
-
(1999)
Eur J Immunol
, vol.29
, pp. 4011-4021
-
-
Foster, S.J.1
Dorner, T.2
Lipsky, P.E.3
-
36
-
-
0027932998
-
H genes are inherently susceptible to amino acid replacement
-
H genes are inherently susceptible to amino acid replacement. Immunol Today 15:367-373, 1994
-
(1994)
Immunol Today
, vol.15
, pp. 367-373
-
-
Chang, B.1
Casali, P.2
-
37
-
-
0031569118
-
Analysis of the frequency and pattern of somatic mutations within nonproductively rearranged human variable heavy chain genes
-
Dorner T, Brezinschek HP, Brezinschek RI, Foster SJ, Domiati-Saad R, Lipsky PE: Analysis of the frequency and pattern of somatic mutations within nonproductively rearranged human variable heavy chain genes. J Immunol 158:2779-2789, 1997
-
(1997)
J Immunol
, vol.158
, pp. 2779-2789
-
-
Dorner, T.1
Brezinschek, H.P.2
Brezinschek, R.I.3
Foster, S.J.4
Domiati-Saad, R.5
Lipsky, P.E.6
-
38
-
-
0036499127
-
Evolution of Ig DNA sequence to target specific base positions within codons for somatic hypermutation
-
Shapiro GS, Aviszus K, Murphy J, Wysocki LJ: Evolution of Ig DNA sequence to target specific base positions within codons for somatic hypermutation. J Immunol 168:2302-2306, 2002
-
(2002)
J Immunol
, vol.168
, pp. 2302-2306
-
-
Shapiro, G.S.1
Aviszus, K.2
Murphy, J.3
Wysocki, L.J.4
-
39
-
-
0028270307
-
Elements regulating somatic hypermutation of an immunoglobulin κ gene: Critical role for the intron enhancer/matrix attachment region
-
Betz AG, Milstein C, Gonzalez-Fernandez A, Pannell R, Larson T, Neuberger MS: Elements regulating somatic hypermutation of an immunoglobulin κ gene: Critical role for the intron enhancer/matrix attachment region. Cell 77:239-248, 1994
-
(1994)
Cell
, vol.77
, pp. 239-248
-
-
Betz, A.G.1
Milstein, C.2
Gonzalez-Fernandez, A.3
Pannell, R.4
Larson, T.5
Neuberger, M.S.6
-
40
-
-
0031009483
-
Cells strongly expressing Ig(κ) transgenes show clonal recruitment of hypermutation: A role for both MAR and the enhancers
-
Goyenechea B, Klix N, Yelamos J, Williams GT, Riddell A, Neuberger MS, Milstein C: Cells strongly expressing Ig(κ) transgenes show clonal recruitment of hypermutation: A role for both MAR and the enhancers. EMBO J 16:3987-3994, 1997
-
(1997)
EMBO J
, vol.16
, pp. 3987-3994
-
-
Goyenechea, B.1
Klix, N.2
Yelamos, J.3
Williams, G.T.4
Riddell, A.5
Neuberger, M.S.6
Milstein, C.7
-
41
-
-
0031975171
-
Multiple sequences from downstream of the J κ cluster can combine to recruit somatic hypermutation to a heterologous, upstream mutation domain
-
Klix N, Jolly CJ, Davies SL, Bruggemann M, Williams GT, Neuberger MS: Multiple sequences from downstream of the J κ cluster can combine to recruit somatic hypermutation to a heterologous, upstream mutation domain. Eur J Immunol 28:317-326, 1998
-
(1998)
Eur J Immunol
, vol.28
, pp. 317-326
-
-
Klix, N.1
Jolly, C.J.2
Davies, S.L.3
Bruggemann, M.4
Williams, G.T.5
Neuberger, M.S.6
-
43
-
-
0014019617
-
Origin of antibody variation
-
Brenner S, Milstein C: Origin of antibody variation. Nature 211:242-243, 1966
-
(1966)
Nature
, vol.211
, pp. 242-243
-
-
Brenner, S.1
Milstein, C.2
-
44
-
-
0037019315
-
AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification
-
Petersen-Mahrt SK, Harris RS, Neuberger MS: AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification. Nature 418:99-103, 2002
-
(2002)
Nature
, vol.418
, pp. 99-103
-
-
Petersen-Mahrt, S.K.1
Harris, R.S.2
Neuberger, M.S.3
-
45
-
-
0037026482
-
Altering the pathway of immunoglobulin hypermutation by inhibiting uracil-DNA glycosylase
-
Di Noia J, Neuberger MS: Altering the pathway of immunoglobulin hypermutation by inhibiting uracil-DNA glycosylase. Nature 419:43-48, 2002
-
(2002)
Nature
, vol.419
, pp. 43-48
-
-
Di Noia, J.1
Neuberger, M.S.2
-
46
-
-
0037108463
-
Immunoglobulin isotype switching is inhibited and somatic hypermutation perturbed in UNG-deficient mice
-
Rada C, Williams GT, Nilsen H, Barnes DE, Lindhal T, Neuberger MS: Immunoglobulin isotype switching is inhibited and somatic hypermutation perturbed in UNG-deficient mice. Curr Biol 12:1748-1755, 2002
-
(2002)
Curr Biol
, vol.12
, pp. 1748-1755
-
-
Rada, C.1
Williams, G.T.2
Nilsen, H.3
Barnes, D.E.4
Lindhal, T.5
Neuberger, M.S.6
-
47
-
-
0032478071
-
Frequent occurrence of deletions and duplications during somatic hypermutation: Implications for oncogene translocations and heavy chain disease
-
Goossens T, Klein U, Kuppers R: Frequent occurrence of deletions and duplications during somatic hypermutation: Implications for oncogene translocations and heavy chain disease. Proc Natl Acad Sci USA 95:2463-2468, 1998
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 2463-2468
-
-
Goossens, T.1
Klein, U.2
Kuppers, R.3
-
48
-
-
0031983725
-
Somatic hypermutation introduces insertions and deletions into immunoglobulin V genes
-
Wilson PC, de Bouteiller O, Liu YJ, Potter K, Banchereau J, Capra JD, Pascual V: Somatic hypermutation introduces insertions and deletions into immunoglobulin V genes. J Exp Med 187:59-70, 1998
-
(1998)
J Exp Med
, vol.187
, pp. 59-70
-
-
Wilson, P.C.1
De Bouteiller, O.2
Liu, Y.J.3
Potter, K.4
Banchereau, J.5
Capra, J.D.6
Pascual, V.7
-
49
-
-
0032435650
-
TdT-accessible breaks are scattered over the immunoglobulin V domain in a constitutively hypermutating B cell line
-
Sale JE, Neuberger MS: TdT-accessible breaks are scattered over the immunoglobulin V domain in a constitutively hypermutating B cell line. Immunity 9:859-869, 1998
-
(1998)
Immunity
, vol.9
, pp. 859-869
-
-
Sale, J.E.1
Neuberger, M.S.2
-
50
-
-
0034626802
-
Cell-cycle-regulated DNA double-stranded breaks in somatic hypermutation of immunoglobulin genes
-
Papavasiliou FN, Schatz DG: Cell-cycle-regulated DNA double-stranded breaks in somatic hypermutation of immunoglobulin genes. Nature 408:216-221, 2000
-
(2000)
Nature
, vol.408
, pp. 216-221
-
-
Papavasiliou, F.N.1
Schatz, D.G.2
-
51
-
-
0033637358
-
DNA double-strand breaks in immunoglobulin genes undergoing somatic hypermutation
-
Bross L, Fukita Y, McBlane F, Demolliere C, Rajewsky K, Jacobs H: DNA double-strand breaks in immunoglobulin genes undergoing somatic hypermutation. Immunity 13:589-597, 2000
-
(2000)
Immunity
, vol.13
, pp. 589-597
-
-
Bross, L.1
Fukita, Y.2
McBlane, F.3
Demolliere, C.4
Rajewsky, K.5
Jacobs, H.6
-
52
-
-
0038771252
-
AID-dependent generation of resected double-strand DNA breaks and recruitment of Rad52/Rad51 in somatic hypermutation
-
in press
-
Zan H, Wu X, Komori A, Holloman WK, Casali P: AID-dependent generation of resected double-strand DNA breaks and recruitment of Rad52/Rad51 in somatic hypermutation. Immunity in press
-
Immunity
-
-
Zan, H.1
Wu, X.2
Komori, A.3
Holloman, W.K.4
Casali, P.5
-
53
-
-
0034644134
-
The c-MYC allele that is translocated into the Ig H locus undergoes constitutive hypermutation in a Burkitt's lymphoma line
-
Bemark M, Neuberger MS: The c-MYC allele that is translocated into the Ig H locus undergoes constitutive hypermutation in a Burkitt's lymphoma line. Oncogene 19:3404-3410, 2000
-
(2000)
Oncogene
, vol.19
, pp. 3404-3410
-
-
Bemark, M.1
Neuberger, M.S.2
-
55
-
-
0034694086
-
Somatic hypermutation in the absence of DNA-dependent protein kinase catalytic subunit (DNA-PK(cs)) or recombination-activating gene (RAG) 1 activity
-
Bemark M, Sale J, Kim HJ, Berek C, Cosgrove RA, Neuberger MS: Somatic hypermutation in the absence of DNA-dependent protein kinase catalytic subunit (DNA-PK(cs)) or recombination-activating gene (RAG)1 activity. J Exp Med 192:1509-1514, 2000
-
(2000)
J Exp Med
, vol.192
, pp. 1509-1514
-
-
Bemark, M.1
Sale, J.2
Kim, H.J.3
Berek, C.4
Cosgrove, R.A.5
Neuberger, M.S.6
-
56
-
-
0036178823
-
Mice deficient for the type II topoisomerase-like DNA transesterase Spo11 show normal immunoglobulin somatic hypermutation and class switching
-
Klein U, Esposito G, Baudat F, Keeney S, Jasin M: Mice deficient for the type II topoisomerase-like DNA transesterase Spo11 show normal immunoglobulin somatic hypermutation and class switching. Eur J Immunol 32:316-321, 2002
-
(2002)
Eur J Immunol
, vol.32
, pp. 316-321
-
-
Klein, U.1
Esposito, G.2
Baudat, F.3
Keeney, S.4
Jasin, M.5
-
57
-
-
0033603340
-
Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cells
-
Muramatsu M, Sankaranand VS, Anant S, Sugai M, Kinoshita K, Davidson NO, Honjo T: Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cells. J Biol Chem 274:18470-18476, 1999
-
(1999)
J Biol Chem
, vol.274
, pp. 18470-18476
-
-
Muramatsu, M.1
Sankaranand, V.S.2
Anant, S.3
Sugai, M.4
Kinoshita, K.5
Davidson, N.O.6
Honjo, T.7
-
58
-
-
0037029606
-
The activation-induced deaminase functions in a postcleavage step of the somatic hypermutation process
-
Papavasiliou FN, Schatz DG: The activation-induced deaminase functions in a postcleavage step of the somatic hypermutation process. J Exp Med 195:1193-1198, 2002
-
(2002)
J Exp Med
, vol.195
, pp. 1193-1198
-
-
Papavasiliou, F.N.1
Schatz, D.G.2
-
59
-
-
0037029663
-
DNA double-strand breaks: Prior to but not sufficient in targeting hypermutation
-
Bross L, Muramatsu M, Kinoshita K, Honjo T, Jacobs H: DNA double-strand breaks: Prior to but not sufficient in targeting hypermutation. J Exp Med 195:1187-1192, 2002
-
(2002)
J Exp Med
, vol.195
, pp. 1187-1192
-
-
Bross, L.1
Muramatsu, M.2
Kinoshita, K.3
Honjo, T.4
Jacobs, H.5
-
60
-
-
0035313995
-
Towards an understanding of somatic hypermutation
-
Jacobs H, Bross L: Towards an understanding of somatic hypermutation. Curr Opin Immunal 13:208-218, 2001
-
(2001)
Curr Opin Immunal
, vol.13
, pp. 208-218
-
-
Jacobs, H.1
Bross, L.2
-
61
-
-
0037418279
-
Inaugural Article: De novo protein synthesis is required for the activation-induced cytidine deaminase function in class-switch recombination
-
Doi T, Kinoshita K, Ikegawa M, Muramatsu M, Honjo T: Inaugural Article: De novo protein synthesis is required for the activation-induced cytidine deaminase function in class-switch recombination. Proc Natl Acad Sci USA 100:2634-2638, 2003
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 2634-2638
-
-
Doi, T.1
Kinoshita, K.2
Ikegawa, M.3
Muramatsu, M.4
Honjo, T.5
-
62
-
-
0037388165
-
Activation-induced cytidine deaminase deaminates deoxycytidine on single-stranded DNA but requires the action of RNase
-
Bransteitter R, Pham P, Scharff MD, Goodman MF: Activation-induced cytidine deaminase deaminates deoxycytidine on single-stranded DNA but requires the action of RNase. Proc Natl Acad Sci USA 100:4102-4107, 2003
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 4102-4107
-
-
Bransteitter, R.1
Pham, P.2
Scharff, M.D.3
Goodman, M.F.4
-
63
-
-
0032143823
-
Probing immunoglobulin gene hypermutation with microsatellites suggests a nonreplicative short patch DNA synthesis process
-
Bertocci B, Quint L, Delbos F, Garcia C, Reynaud CA, Weill JC: Probing immunoglobulin gene hypermutation with microsatellites suggests a nonreplicative short patch DNA synthesis process. Immunity 9:257-265, 1998
-
(1998)
Immunity
, vol.9
, pp. 257-265
-
-
Bertocci, B.1
Quint, L.2
Delbos, F.3
Garcia, C.4
Reynaud, C.A.5
Weill, J.C.6
-
64
-
-
0035966779
-
Mutagenesis in eukaryotes dependent on DNA polymerase zetaand Rev1p
-
Lawrence CW, Maher VM: Mutagenesis in eukaryotes dependent on DNA polymerase zetaand Rev1p. Philos Trans R Soc London B Biol Sci 356:41-46, 2001
-
(2001)
Philos Trans R Soc London B Biol Sci
, vol.356
, pp. 41-46
-
-
Lawrence, C.W.1
Maher, V.M.2
-
65
-
-
0035860310
-
Error rate and specificity of human and murine DNA polymerase eta
-
Matsuda T, Bebenek K, Masutani C, Rogozin IB, Hanaoka F, Kunkel TA: Error rate and specificity of human and murine DNA polymerase eta. J Mol Biol 312:335-346, 2001
-
(2001)
J Mol Biol
, vol.312
, pp. 335-346
-
-
Matsuda, T.1
Bebenek, K.2
Masutani, C.3
Rogozin, I.B.4
Hanaoka, F.5
Kunkel, T.A.6
-
66
-
-
0035966775
-
DNA polymerase iota and related rad30-like enzymes
-
McDonald JP, Tissier A, Frank EG, Iwai S, Hanaoka F, Woodgate R: DNA polymerase iota and related rad30-like enzymes. Philos Trans R Soc Lond B Biol Sci 356:53-60, 2001
-
(2001)
Philos Trans R Soc Lond B Biol Sci
, vol.356
, pp. 53-60
-
-
McDonald, J.P.1
Tissier, A.2
Frank, E.G.3
Iwai, S.4
Hanaoka, F.5
Woodgate, R.6
-
67
-
-
0034720285
-
Low fidelity DNA synthesis by human DNA polymerase-η
-
Matsuda T, Bebenek K, Masutani C, Hanaoka F, Kunkel TA: Low fidelity DNA synthesis by human DNA polymerase-η. Nature 404:1011-1013, 2000
-
(2000)
Nature
, vol.404
, pp. 1011-1013
-
-
Matsuda, T.1
Bebenek, K.2
Masutani, C.3
Hanaoka, F.4
Kunkel, T.A.5
-
68
-
-
0037090311
-
Cutting edge: DNA polymerases μ and λ are dispensable for Ig gene hypermutation
-
Bertocci B, De Smet A, Flatter E, Dahan A, Bories JC, Landreau C, Weill JC, Reynaud CA: Cutting edge: DNA polymerases μ and λ are dispensable for Ig gene hypermutation. J Immunol 168:3702-3706, 2002
-
(2002)
J Immunol
, vol.168
, pp. 3702-3706
-
-
Bertocci, B.1
De Smet, A.2
Flatter, E.3
Dahan, A.4
Bories, J.C.5
Landreau, C.6
Weill, J.C.7
Reynaud, C.A.8
-
69
-
-
0033974775
-
Mice reconstituted with DNA polymerase β-deficient fetal liver cells are able to mount a T cell-dependent immune response and mutate their Ig genes normally
-
Esposito G, Texido G, Betz UA, Gu H, Muller W, Klein U, Rajewsky K: Mice reconstituted with DNA polymerase β-deficient fetal liver cells are able to mount a T cell-dependent immune response and mutate their Ig genes normally. Proc Natl Acad Sci USA 97: 1166-1171, 2000
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 1166-1171
-
-
Esposito, G.1
Texido, G.2
Betz, U.A.3
Gu, H.4
Muller, W.5
Klein, U.6
Rajewsky, K.7
-
70
-
-
0036859318
-
DNA polymerase κ deficiency does not affect somatic hypermutation in mice
-
Schenten D, Gerlach VL, Guo C, Velasco-Miguel S, Hladik CL, White CL, Friedberg EC, Rajewsky K, Esposito G: DNA polymerase κ deficiency does not affect somatic hypermutation in mice. Eur J Immunol 32:3152-3160, 2002
-
(2002)
Eur J Immunol
, vol.32
, pp. 3152-3160
-
-
Schenten, D.1
Gerlach, V.L.2
Guo, C.3
Velasco-Miguel, S.4
Hladik, C.L.5
White, C.L.6
Friedberg, E.C.7
Rajewsky, K.8
Esposito, G.9
-
71
-
-
0037384973
-
Ig gene somatic hypermutation in mice defective for DNA polymerase δ proofreading
-
Longacre A, Sun T, Goldsby RE, Preston BD, Storb U: Ig gene somatic hypermutation in mice defective for DNA polymerase δ proofreading. Int Immunol 15:477-481, 2003
-
(2003)
Int Immunol
, vol.15
, pp. 477-481
-
-
Longacre, A.1
Sun, T.2
Goldsby, R.E.3
Preston, B.D.4
Storb, U.5
-
72
-
-
0034677798
-
Specificity of DNA lesion bypass by the yeast DNA polymerase η
-
Yuan F, Zhang Y, Rajpal DK, Wu X, Guo D, Wang W, Taylor JS, Wang Z: Specificity of DNA lesion bypass by the yeast DNA polymerase η. J Biol Chem 275:8233-8293, 2001
-
(2001)
J Biol Chem
, vol.275
, pp. 8233-8293
-
-
Yuan, F.1
Zhang, Y.2
Rajpal, D.K.3
Wu, X.4
Guo, D.5
Wang, W.6
Taylor, J.S.7
Wang, Z.8
-
73
-
-
0034738983
-
Eukaryotic polymerases ι and ζ act sequentially to bypass DNA lesions
-
Johnson RE, Washington MT, Haracska L, Prakash S, Prakash L: Eukaryotic polymerases ι and ζ act sequentially to bypass DNA lesions. Nature 406:1015-1019, 2000
-
(2000)
Nature
, vol.406
, pp. 1015-1019
-
-
Johnson, R.E.1
Washington, M.T.2
Haracska, L.3
Prakash, S.4
Prakash, L.5
-
74
-
-
0030700468
-
A role for REV3 in mutagenesis during double-strand break repair in Saccharomyces cerevisiae
-
Holbeck SL, Strathern JN: A role for REV3 in mutagenesis during double-strand break repair in Saccharomyces cerevisiae. Genetics 147:1017-1024, 1997
-
(1997)
Genetics
, vol.147
, pp. 1017-1024
-
-
Holbeck, S.L.1
Strathern, J.N.2
-
75
-
-
0031894290
-
Evolution of somatic hypermutation and gene conversion in adaptive immunity
-
Diaz M, Flajnik MF: Evolution of somatic hypermutation and gene conversion in adaptive immunity. Immunol Rev 162:13-24, 1998
-
(1998)
Immunol Rev
, vol.162
, pp. 13-24
-
-
Diaz, M.1
Flajnik, M.F.2
-
76
-
-
0035005241
-
The translesion DNA polymerase ζ plays a major role in Ig and bcl- 6 somatic hypermutation
-
Zan H, Komori A, Li Z, Cerutti A, Schaffer A, Flajnik MF, Diaz M, Casali P: The translesion DNA polymerase ζ plays a major role in Ig and bcl-6 somatic hypermutation. Immunity 14:634-653, 2001
-
(2001)
Immunity
, vol.14
, pp. 634-653
-
-
Zan, H.1
Komori, A.2
Li, Z.3
Cerutti, A.4
Schaffer, A.5
Flajnik, M.F.6
Diaz, M.7
Casali, P.8
-
77
-
-
0035399804
-
Decreased frequency of somatic hypermutation and impaired affinity maturation but intact germinal center formation in nice expressing antisense RNA to DNA polymerase ζ
-
Diaz M, Verkoczy LK, Flajnik MF, Kliman NR: Decreased frequency of somatic hypermutation and impaired affinity maturation but intact germinal center formation in nice expressing antisense RNA to DNA polymerase ζ. J Immunol 167:327-335, 2001
-
(2001)
J Immunol
, vol.167
, pp. 327-335
-
-
Diaz, M.1
Verkoczy, L.K.2
Flajnik, M.F.3
Kliman, N.R.4
-
78
-
-
0037206851
-
Induction of sonatic hypermutation in immunoglobulin genes is dependent on DNA polymerase ι
-
Faili A, Aoufouchi S, Flatter E, Gueranger Q, Reynaud CA, Weill JC: Induction of sonatic hypermutation in immunoglobulin genes is dependent on DNA polymerase ι. Nature 419:944-947, 2002
-
(2002)
Nature
, vol.419
, pp. 944-947
-
-
Faili, A.1
Aoufouchi, S.2
Flatter, E.3
Gueranger, Q.4
Reynaud, C.A.5
Weill, J.C.6
-
79
-
-
0035377269
-
DNA polymerase η is an A-T mutator in somatic hypermutation of immunoglobulin variable genes
-
Zeng X, Winter DB, Kasmer C, Kraemer KH, Lehmann AR, Gearhart PJ: DNA polymerase η is an A-T mutator in somatic hypermutation of immunoglobulin variable genes. Nat Immunol 2:537-541, 2001
-
(2001)
Nat Immunol
, vol.2
, pp. 537-541
-
-
Zeng, X.1
Winter, D.B.2
Kasmer, C.3
Kraemer, K.H.4
Lehmann, A.R.5
Gearhart, P.J.6
-
80
-
-
0035379581
-
Somatic mutation hotspots correlate with DNA polymerase η error spectrum
-
Rogozin IB, Pavlov YI, Bebenek K, Matsuda T, Kunkel TA: Somatic mutation hotspots correlate with DNA polymerase η error spectrum. Nat Immunol 2:530-536, 2001
-
(2001)
Nat Immunol
, vol.2
, pp. 530-536
-
-
Rogozin, I.B.1
Pavlov, Y.I.2
Bebenek, K.3
Matsuda, T.4
Kunkel, T.A.5
-
81
-
-
0037162552
-
Correlation of somatic hypermutation specificity and A-T base pair substitution errors by DNA polymerase η during copying of a mouse immunoglobulin κ light chain transgene
-
Pavlov YI, Rogozin IB, Galkin AP, Aksenova AY, Hanaoka F, Rada C, Kunkel TA: Correlation of somatic hypermutation specificity and A-T base pair substitution errors by DNA polymerase η during copying of a mouse immunoglobulin κ light chain transgene. Proc Natl Acad Sci USA 99:9954-9959, 2002
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 9954-9959
-
-
Pavlov, Y.I.1
Rogozin, I.B.2
Galkin, A.P.3
Aksenova, A.Y.4
Hanaoka, F.5
Rada, C.6
Kunkel, T.A.7
-
82
-
-
0036786471
-
The role of polymerase η in somatic hypermutation determined by analysis of mutations in a patient with xeroderma pigmentosum variant
-
Yavuz S, Yavuz AS, Kraemer KH, Lipsky PE: The role of polymerase η in somatic hypermutation determined by analysis of mutations in a patient with xeroderma pigmentosum variant. J Immunol 169:3825-3830, 2002
-
(2002)
J Immunol
, vol.169
, pp. 3825-3830
-
-
Yavuz, S.1
Yavuz, A.S.2
Kraemer, K.H.3
Lipsky, P.E.4
-
83
-
-
0036732772
-
AID-dependent somatic hypermutation occurs as a DNA single-strand event in the BL 2 cell line
-
Faili A, Aoufouchi S, Gueranger Q, Zober C, Leon A, Bertocci B, Weill JC, Reynaud CA: AID-dependent somatic hypermutation occurs as a DNA single-strand event in the BL2 cell line. Nat Immunol 3:815-821, 2002
-
(2002)
Nat Immunol
, vol.3
, pp. 815-821
-
-
Faili, A.1
Aoufouchi, S.2
Gueranger, Q.3
Zober, C.4
Leon, A.5
Bertocci, B.6
Weill, J.C.7
Reynaud, C.A.8
|