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Volumn 159, Issue 7, 1997, Pages 3347-3353

In Vitro Triggering of Somatic Mutation in Human Naive B Cells

Author keywords

[No Author keywords available]

Indexed keywords

CD3 ANTIGEN; IMMUNOGLOBULIN CLASS; IMMUNOGLOBULIN D; LYMPHOCYTE ANTIGEN RECEPTOR; MONOCLONAL ANTIBODY;

EID: 0031252393     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (25)

References (48)
  • 2
    • 0026331458 scopus 로고
    • Maturation of the immune response in germinal centers
    • Berek, C., A. Berger, and M. Apel. 1991. Maturation of the immune response in germinal centers. Cell 67:1121.
    • (1991) Cell , vol.67 , pp. 1121
    • Berek, C.1    Berger, A.2    Apel, M.3
  • 3
    • 0027476846 scopus 로고
    • Immunological memory
    • Gray, D. 1993. Immunological memory. Annu. Rev. Immunol. 11:49.
    • (1993) Annu. Rev. Immunol. , vol.11 , pp. 49
    • Gray, D.1
  • 5
    • 0021186174 scopus 로고
    • Asynchronous depression of responses to T- and B-cell mitogens during acute infection with cytomegalovirus in the guinea pig
    • Griffith, B. P., J. T. Lavallee, J. Booss, and G. D. Hsiung. 1984. Asynchronous depression of responses to T- and B-cell mitogens during acute infection with cytomegalovirus in the guinea pig. Cell. Immunol. 87:727.
    • (1984) Cell. Immunol. , vol.87 , pp. 727
    • Griffith, B.P.1    Lavallee, J.T.2    Booss, J.3    Hsiung, G.D.4
  • 6
    • 0027491651 scopus 로고
    • Tracing B cell development in human germinal centres by molecular analysis of single cells picked from histological sections
    • Kuppers, R., M. Zhao, M. L. Hansmann, and K. Rajewsky. 1993. Tracing B cell development in human germinal centres by molecular analysis of single cells picked from histological sections. EMBO J. 12:4955.
    • (1993) EMBO J. , vol.12 , pp. 4955
    • Kuppers, R.1    Zhao, M.2    Hansmann, M.L.3    Rajewsky, K.4
  • 7
    • 0026060620 scopus 로고
    • Intraclonal generation of antibody mutants in germinal centres
    • Jacob, J., G. Kelsoe, K. Rajewsky, and U. Weiss. 1991. Intraclonal generation of antibody mutants in germinal centres. Nature 354:389.
    • (1991) Nature , vol.354 , pp. 389
    • Jacob, J.1    Kelsoe, G.2    Rajewsky, K.3    Weiss, U.4
  • 10
    • 0028005612 scopus 로고
    • Somatic mutation: From the dark zone to the light
    • MacLennan, I. C. M. 1994. Somatic mutation: from the dark zone to the light. Curr. Biol. 4:70.
    • (1994) Curr. Biol. , vol.4 , pp. 70
    • MacLennan, I.C.M.1
  • 12
    • 0029052398 scopus 로고
    • Cellular interaction in germinal centers: Roles of CD40 ligand and B7-2 in established germinal centers
    • Han, S., K. Hathcock, B. Kheng, T. B. Kepler, R. Hodes, and G. Kelsoe. 1995. Cellular interaction in germinal centers: roles of CD40 ligand and B7-2 in established germinal centers. J. Immunol. 155:556.
    • (1995) J. Immunol. , vol.155 , pp. 556
    • Han, S.1    Hathcock, K.2    Kheng, B.3    Kepler, T.B.4    Hodes, R.5    Kelsoe, G.6
  • 13
    • 0028807328 scopus 로고
    • In situ studies of the germinal center reaction
    • Kelsoe, G. 1995. In situ studies of the germinal center reaction. Adv. Immunol. 60:267.
    • (1995) Adv. Immunol. , vol.60 , pp. 267
    • Kelsoe, G.1
  • 14
    • 0028128577 scopus 로고
    • Development of antibody diversity in single germinal centers: Selective expansion of high-affinity variants
    • Ziegner, M., G. Steinhauser, and C. Berek. 1994. Development of antibody diversity in single germinal centers: selective expansion of high-affinity variants. Eur. J. Immunol. 24:2393.
    • (1994) Eur. J. Immunol. , vol.24 , pp. 2393
    • Ziegner, M.1    Steinhauser, G.2    Berek, C.3
  • 15
    • 0024327901 scopus 로고
    • Stable expression and somatic hypermutation of antibody V regions in B-cell developmental pathways
    • Kocks, C., and K. Rajewsky. 1989. Stable expression and somatic hypermutation of antibody V regions in B-cell developmental pathways. Annu. Rev. Immunol. 7:517.
    • (1989) Annu. Rev. Immunol. , vol.7 , pp. 517
    • Kocks, C.1    Rajewsky, K.2
  • 16
    • 0019794854 scopus 로고
    • Differences between germ-line and rearranged immunoglobulin V kappa coding sequences suggest a localized mutation mechanism
    • Pech, M., J. Hochtl, H. Schnell, and H. G. Zachau. 1981. Differences between germ-line and rearranged immunoglobulin V kappa coding sequences suggest a localized mutation mechanism. Nature 291:668.
    • (1981) Nature , vol.291 , pp. 668
    • Pech, M.1    Hochtl, J.2    Schnell, H.3    Zachau, H.G.4
  • 17
    • 0025630537 scopus 로고
    • Boundaries of somatic mutation in rearranged immunoglobulin genes: 5′ boundary is near the promoter, and 3′ boundary is ≈ 1 kb from V(D)J gene
    • Lebecque, S. G., and P. J. Gearhart. 1990. Boundaries of somatic mutation in rearranged immunoglobulin genes: 5′ boundary is near the promoter, and 3′ boundary is ≈ 1 kb from V(D)J gene. J. Exp. Med. 172:1717.
    • (1990) J. Exp. Med. , vol.172 , pp. 1717
    • Lebecque, S.G.1    Gearhart, P.J.2
  • 19
    • 0008476550 scopus 로고
    • Generation of antibody diversity in the immune response of BALB/c mice to influenza virus hemagglutinin
    • McKean, D., K. Huppi, M. Bell, L. Staudt, W. Gerhard, and M. Weigert. 1984. Generation of antibody diversity in the immune response of BALB/c mice to influenza virus hemagglutinin. Proc. Natl. Acad. Sci. USA 81:3180.
    • (1984) Proc. Natl. Acad. Sci. USA , vol.81 , pp. 3180
    • McKean, D.1    Huppi, K.2    Bell, M.3    Staudt, L.4    Gerhard, W.5    Weigert, M.6
  • 20
    • 0023161406 scopus 로고
    • Mutation drift and repertoire shift in the maturation of the immune response
    • Berek, C., and C. Milstein. 1987. Mutation drift and repertoire shift in the maturation of the immune response. Immunol. Rev. 96:23.
    • (1987) Immunol. Rev. , vol.96 , pp. 23
    • Berek, C.1    Milstein, C.2
  • 22
    • 0003575039 scopus 로고
    • Stepwise intraclonal maturation of antibody affinity through somatic hypermutation
    • Kocks, C., and K. Rajewsky. 1988. Stepwise intraclonal maturation of antibody affinity through somatic hypermutation. Proc. Natl. Acad. Sci. USA 85:8206.
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 8206
    • Kocks, C.1    Rajewsky, K.2
  • 23
    • 0027227311 scopus 로고
    • Discriminating intrinsic and antigen-selected tnutational hotspots in immunoglobulin V genes
    • Betz, A. G., M. S. Neuberger, and C. Milstein. 1993. Discriminating intrinsic and antigen-selected tnutational hotspots in immunoglobulin V genes. Immunol. Today 14:405.
    • (1993) Immunol. Today , vol.14 , pp. 405
    • Betz, A.G.1    Neuberger, M.S.2    Milstein, C.3
  • 24
    • 0022018911 scopus 로고
    • Somatic mutation and clonal expansion of B cells in an antigen-driven immune response
    • Sablitzky, F., G. Wildner, and K. Rajewsky. 1985. Somatic mutation and clonal expansion of B cells in an antigen-driven immune response. EMBO J. 4:345.
    • (1985) EMBO J. , vol.4 , pp. 345
    • Sablitzky, F.1    Wildner, G.2    Rajewsky, K.3
  • 25
    • 0030063726 scopus 로고    scopus 로고
    • Somatic hypermutation of immunoglobulin genes is linked to transcription initiation
    • Peters, A., and U. Storb. 1996. Somatic hypermutation of immunoglobulin genes is linked to transcription initiation. Immunity 4:57.
    • (1996) Immunity , vol.4 , pp. 57
    • Peters, A.1    Storb, U.2
  • 27
    • 0028270307 scopus 로고
    • Elements regulating somatic hypermutation of an immunoglobulin kappa gene: Critical role for the intron enhancer/matrix attachment region
    • Betz, A. G., C. Milstein, A. Gonzalez-Fernandez, R. Pannell, T. Larson, and M. S. Neuberger. 1994. Elements regulating somatic hypermutation of an immunoglobulin kappa gene: critical role for the intron enhancer/matrix attachment region. Cell 77:219.
    • (1994) Cell , vol.77 , pp. 219
    • Betz, A.G.1    Milstein, C.2    Gonzalez-Fernandez, A.3    Pannell, R.4    Larson, T.5    Neuberger, M.S.6
  • 28
    • 0028904644 scopus 로고
    • Anti-CD40 plus interleukin-4-activated human naive B cell lines express unmutated immunoglobulin genes with intraclonal heavy chain isotype variability
    • Galibert, L., J. van Dooren, I. Durand, F. Rousset, R. Jefferis, J. Banchereau, and S. Lebecque. 1995. Anti-CD40 plus interleukin-4-activated human naive B cell lines express unmutated immunoglobulin genes with intraclonal heavy chain isotype variability. Eur. J. Immunol. 25:733.
    • (1995) Eur. J. Immunol. , vol.25 , pp. 733
    • Galibert, L.1    Van Dooren, J.2    Durand, I.3    Rousset, F.4    Jefferis, R.5    Banchereau, J.6    Lebecque, S.7
  • 31
    • 0023013761 scopus 로고
    • T cell clones which share T cell receptor epitopes differ in phenotype, function and specificity
    • Yssel, H., D. Blanchard, A. Boylston, J. E. de Vries, and H. Spits. 1986. T cell clones which share T cell receptor epitopes differ in phenotype, function and specificity. Eur. J. Immunol. 16:1187.
    • (1986) Eur. J. Immunol. , vol.16 , pp. 1187
    • Yssel, H.1    Blanchard, D.2    Boylston, A.3    De Vries, J.E.4    Spits, H.5
  • 32
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidium thiocyanate-phenol-chloroform extraction
    • Chomczynski, P., and N. Sacchi. 1987. Single-step method of RNA isolation by acid guanidium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162: 156.
    • (1987) Anal. Biochem. , vol.162 , pp. 156
    • Chomczynski, P.1    Sacchi, N.2
  • 33
    • 0028568131 scopus 로고
    • Five human mature B cell subsets
    • E. Heinen, M. P. Defresne, J. Boniver, and V. Geenen, eds. Plenum Press, New York
    • Liu, Y. J., O. de Bouteiller, C. Arpin, I. Durand, and J. Banchereau. 1994. Five human mature B cell subsets. In In Vivo Immunology. E. Heinen, M. P. Defresne, J. Boniver, and V. Geenen, eds. Plenum Press, New York, pp. 289-294.
    • (1994) In Vivo Immunology , pp. 289-294
    • Liu, Y.J.1    De Bouteiller, O.2    Arpin, C.3    Durand, I.4    Banchereau, J.5
  • 34
    • 0029903587 scopus 로고    scopus 로고
    • Mutant mice without B lymphocyte follicles
    • Liu, Y. J., and J. Banchereau. 1996. Mutant mice without B lymphocyte follicles. J. Exp. Med. 184:1207.
    • (1996) J. Exp. Med. , vol.184 , pp. 1207
    • Liu, Y.J.1    Banchereau, J.2
  • 35
    • 0028079632 scopus 로고
    • Role of CD40 antigen and interleukin-2 in T cell dependent human B lymphocyte growth
    • Blanchard, D., C. Gaillard, P. Hermann, and J. Banchereau. 1994. Role of CD40 antigen and interleukin-2 in T cell dependent human B lymphocyte growth. Eur. J. Immunol. 24:330.
    • (1994) Eur. J. Immunol. , vol.24 , pp. 330
    • Blanchard, D.1    Gaillard, C.2    Hermann, P.3    Banchereau, J.4
  • 36
    • 0026569476 scopus 로고
    • Anti-CD3-stimulated T cells induce the production of multiple IgH chain isotypes by individual human peripheral B lymphocytes
    • Kelly, P. J., V. Pascual, J. D. Capra, and P. E. Lipsky. 1992. Anti-CD3-stimulated T cells induce the production of multiple IgH chain isotypes by individual human peripheral B lymphocytes. J. Immunol. 148:1294.
    • (1992) J. Immunol. , vol.148 , pp. 1294
    • Kelly, P.J.1    Pascual, V.2    Capra, J.D.3    Lipsky, P.E.4
  • 39
    • 0023107028 scopus 로고
    • Patterns of somatic mutations in immunoglobulin variable genes
    • Golding, G. B., P. J. Gearhart, and B. W. Glickman. 1987. Patterns of somatic mutations in immunoglobulin variable genes. Genetics 115:169.
    • (1987) Genetics , vol.115 , pp. 169
    • Golding, G.B.1    Gearhart, P.J.2    Glickman, B.W.3
  • 40
  • 41
    • 0027932998 scopus 로고
    • H genes are inherently susceptible to amino acid replacement
    • H genes are inherently susceptible to amino acid replacement. Immunol. Today 15:367.
    • (1994) Immunol. Today , vol.15 , pp. 367
    • Chang, B.1    Casali, P.2
  • 42
    • 0024802909 scopus 로고
    • Primary antibody-forming cells and secondary B cells are generated from separate precursor cell subpopulations
    • Linton, P. J., D. J. Decker, and N. R. Klinman. 1989. Primary antibody-forming cells and secondary B cells are generated from separate precursor cell subpopulations. Cell 59:1049.
    • (1989) Cell , vol.59 , pp. 1049
    • Linton, P.J.1    Decker, D.J.2    Klinman, N.R.3
  • 43
    • 0026552673 scopus 로고
    • Among naive precursor cell subpopulations only progenitors of memory B cells originate germinal centers
    • Linton, P. J., D. Lo, L. Lai, G. J. Thorbecke, and N. R. Klinman. 1992. Among naive precursor cell subpopulations only progenitors of memory B cells originate germinal centers. Eur. J. Immunol. 22:1293.
    • (1992) Eur. J. Immunol. , vol.22 , pp. 1293
    • Linton, P.J.1    Lo, D.2    Lai, L.3    Thorbecke, G.J.4    Klinman, N.R.5
  • 44
    • 0028961269 scopus 로고
    • Denning subsets of naive and memory B cells based on the ability of their progeny to somatically mutate in vitro
    • Decker, D. J., P. J. Linton, S. Zaharevitz, M. Biery, T. R. Gingeras, and N. R. Klinman. 1995. Denning subsets of naive and memory B cells based on the ability of their progeny to somatically mutate in vitro. Immunity 2:195.
    • (1995) Immunity , vol.2 , pp. 195
    • Decker, D.J.1    Linton, P.J.2    Zaharevitz, S.3    Biery, M.4    Gingeras, T.R.5    Klinman, N.R.6
  • 46
    • 0025726702 scopus 로고
    • In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl) acetyl. I. The architecture and dynamics of responding cell populations
    • Jacob, J., R. Kassir, and G. Kelsoe. 1991. In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl) acetyl. I. The architecture and dynamics of responding cell populations. J. Exp. Med. 173:1165.
    • (1991) J. Exp. Med. , vol.173 , pp. 1165
    • Jacob, J.1    Kassir, R.2    Kelsoe, G.3
  • 48
    • 0030061131 scopus 로고    scopus 로고
    • CD40 and B cell antigen receptor dual triggering of resting B lymphocytes turns on a partial germinal center phenotype
    • Galibert, L., N. Burdin, B. de Saint-Vis, P. Garrone, C. van Kooten, J. Banchereau, and F. Rousset. 1996. CD40 and B cell antigen receptor dual triggering of resting B lymphocytes turns on a partial germinal center phenotype. J. Exp. Med. 183:77.
    • (1996) J. Exp. Med. , vol.183 , pp. 77
    • Galibert, L.1    Burdin, N.2    De Saint-Vis, B.3    Garrone, P.4    Van Kooten, C.5    Banchereau, J.6    Rousset, F.7


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