Decreased frequency of somatic hypermutation and impaired affinity maturation but intact germinal center formation in mice expressing antisense RNA to DNA polymerase ζ1

Journal of Immunology

Volumn 167, Issue 1, 2001, Pages 327-335

  Diaz, M ^a   Verkoczy, L K ^a   Flajnik, M F ^a   Klinman, N R ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY RNA; CYCLINE; DNA POLYMERASE; GENE PRODUCT; HAPTEN; IMMUNOGLOBULIN G; PROTEIN REV3; REV PROTEIN; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ANTIBODY AFFINITY; ANTIBODY RESPONSE; ARTICLE; B LYMPHOCYTE; CELL MATURATION; CONTROLLED STUDY; GENE EXPRESSION REGULATION; GENE FREQUENCY; GENE SWITCHING; GERMINAL CENTER; IMMUNOGLOBULIN GENE; IMMUNOGLOBULIN VARIABLE REGION; MEMORY CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR AFFINITY; SOMATIC MUTATION;

EID: 0035399804     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.167.1.327     Document Type: Article

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