Cells strongly expressing Igκ transgenes show clonal recruitment of hypermutation: A role for both MAR and the enhancers

EMBO Journal

Volumn 16, Issue 13, 1997, Pages 3987-3994

  Goyenechea, Beatriz ^a   Klix, Norman ^a   Yélamos, José ^a   Williams, Gareth T ^a   Riddell, Andrew ^a   Neuberger, Michael S ^a   Milstein, César ^a  

^a MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

Author keywords

Diversity; Enhancers; Hypermutation; Immunoglobulin; MAR; Somatic mutation

Indexed keywords

IMMUNOGLOBULIN KAPPA CHAIN;

ANIMAL CELL; ARTICLE; B LYMPHOCYTE; CELL NUCLEUS MATRIX; CONTROLLED STUDY; ENHANCER REGION; GENE DELETION; GENE EXPRESSION; GENE MUTATION; IMMUNOGLOBULIN GENE; INTRON; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; TRANSCRIPTION INITIATION; TRANSGENE;

ANIMALS; B-LYMPHOCYTES; BINDING SITES; ENHANCER ELEMENTS (GENETICS); GENE DELETION; GENE EXPRESSION; IMMUNOGLOBULIN KAPPA-CHAINS; MICE; MUTATION; NUCLEAR MATRIX; TRANSGENES;

EID: 0031009483     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/16.13.3987     Document Type: Article

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