메뉴 건너뛰기




Volumn 408, Issue 6809, 2000, Pages 216-221

Cell-cycle-regulated DNA double-strand breaks in somatic hypermutation of immunoglobulin genes

Author keywords

[No Author keywords available]

Indexed keywords

DOUBLE STRANDED DNA; IMMUNOGLOBULIN;

EID: 0034626802     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/35041599     Document Type: Article
Times cited : (232)

References (30)
  • 1
    • 0030006070 scopus 로고    scopus 로고
    • Clonal selection and learning in the antibody system
    • (1996) Nature , vol.381 , pp. 751-758
    • Rajewsky, K.1
  • 3
    • 0031920157 scopus 로고    scopus 로고
    • Monitoring and interpreting the intrinsic features of somatic hypermutation
    • (1998) Immunol. Rev. , vol.162 , pp. 107-116
    • Neuberger, M.S.1
  • 4
    • 0030063726 scopus 로고    scopus 로고
    • Somatic hypermutation of immunoglobulin genes is linked to transcription initiation
    • (1996) Immunity , vol.4 , pp. 57-65
    • Peters, A.1    Storb, U.2
  • 5
    • 0031009483 scopus 로고    scopus 로고
    • Cells strongly expressing Igκ transgenes show clonal recruitment of hypermutation: A role for both MAR and the enhancers
    • (1997) EMBO J. , vol.16 , pp. 3987-3994
    • Goyenechea, B.1
  • 7
    • 0029067875 scopus 로고
    • Targeting of non-Ig sequences in place of the V segment by somatic hypermutation
    • (1995) Nature , vol.376 , pp. 225-229
    • Yelamos, J.1
  • 11
    • 0032435650 scopus 로고    scopus 로고
    • TdT-accessible breaks are scattered over the immunoglobulin variable domain in a constitutively hypermutating B cell line
    • (1998) Immunity , vol.9 , pp. 859-869
    • Sale, J.E.1    Neuberger, M.S.2
  • 13
    • 0023321780 scopus 로고
    • Somatic point mutations in unrearranged immunoglobulin gene segments encoding the variable region of lambda light chains
    • (1987) EMBO J. , vol.6 , pp. 927-932
    • Weiss, S.1    Wu, G.E.2
  • 15
    • 0025368957 scopus 로고
    • Studies on mammalian mutants defective in rejoining double-strand breaks in DNA
    • (1990) Mutat. Res. , vol.239 , pp. 1-16
    • Jeggo, P.A.1
  • 17
    • 0032530658 scopus 로고    scopus 로고
    • Homologous recombination and non-homologous end-joining pathways of DNA double-strand break repair have overlapping roles in the maintenance of chromosomal integrity in vertebrate cells
    • (1998) EMBO J. , vol.17 , pp. 5497-5508
    • Takata, M.1
  • 21
    • 0034596992 scopus 로고    scopus 로고
    • Misinsertion and bypass of thymine-thymine dimers by human DNA polymerase iota
    • (2000) EMBO J. , vol.19 , pp. 5259-5266
    • Tissier, A.1
  • 23
    • 0031983725 scopus 로고    scopus 로고
    • Somatic hypermutation introduces insertions and deletions into immunoglobulin V genes
    • (1998) J. Exp. Med. , vol.187 , pp. 59-70
    • Wilson, P.C.1
  • 24
    • 0031897511 scopus 로고    scopus 로고
    • Somatic hypermutation in normal and transformed human B cells
    • (1998) Immunol. Rev. , vol.162 , pp. 261-280
    • Klein, U.1
  • 25
    • 0033517110 scopus 로고    scopus 로고
    • The liaison of isotype class switch and mismatch repair: An illegitimate affair
    • (1999) J. Exp. Med. , vol.190 , pp. 307-310
    • Kenter, A.L.1
  • 29
    • 0031893762 scopus 로고    scopus 로고
    • The chromosome bias of misincorporations during double-strand break repair is not altered in mismatch repair-defective strains of Saccharomyces cerevisiae
    • (1998) Genetics , vol.148 , pp. 1525-1533
    • McGill, C.B.1    Holbeck, S.L.2    Strathern, J.N.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.