A role for REV3 in mutagenesis during double-strand break repair in Saccharomyces cerevisiae

Genetics

Volumn 147, Issue 3, 1997, Pages 1017-1024

  Holbeck, Susan L ^a   Strathern, Jeffrey N ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA POLYMERASE;

ALLELE; ANIMAL CELL; ARTICLE; DATA ANALYSIS; DNA REPAIR; DNA STRAND BREAKAGE; ENZYME ACTIVITY; FRAMESHIFT MUTATION; HAPLOIDY; NONHUMAN; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; SITE DIRECTED MUTAGENESIS;

ALDOSE-KETOSE ISOMERASES; DEOXYRIBONUCLEASES, TYPE II SITE-SPECIFIC; DNA REPAIR; DNA-DIRECTED DNA POLYMERASE; FRAMESHIFT MUTATION; FUNGAL PROTEINS; MUTAGENESIS; POINT MUTATION; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

ANIMALIA; SACCHAROMYCES CEREVISIAE;

EID: 0030700468     PISSN: 00166731     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (45)

1. ABOUSSEKHRA, A., and R.D. WOOD, 1994 Repair of UV-damaged DNA by mammalian cells and Saccharomyces cerevisiae. Curr. Opin. Genet. Dev. 4: 212-220.
2. ALANI, E., L. CAO and N. KLECKNER, 1987 A method for gene disruption that allows repeated use of URA3 selection in the construction of multiply disrupted yeast strains. Genetics 116: 541-545.
3. BEBENEK, K., W. A. BEARD, J. R. CASAS-FINET, H. R. KIM, T. A. DARDEN et al., 1995 Reduced frameshift fidelity and processivity of HIV-1 reverse transcriptase mutants containing alanine substitutions in helix H of the thumb subdomain. J. Biol. Chem. 270: 19516-19523.
4. BOEKE, J., F. LACROUTE and G. FINK, 1984 A positive selection for mutants lacking orotidine-5′ phosphate decarboxylase activity in yeast: 5-fluoro-orotic acid resistance. Mol. Gen. Genet. 197: 345-346.
5. CAO, L., E. ALANI and N. KLECKNER, 1990 A pathway for generation and processing of double-strand breaks during meiotic recombination in S. cerevisiae. Cell 61: 1089-1101.
6. FOSTER, P. L., and J. CAIRNS, 1992 Mechanisms of directed mutation. Genetics 131: 783-789.
7. FOSTER, P. L., G. GUDMUNDSSON, J. M. TRIMARCHI, H. CAI and M. F. GOODMAN, 1995 Proofreading-defective DNA polymerase II increases adaptive mutation in Escherichia coli. Proc. Natl. Acad. Sci. USA 92: 7951-7955.
8. FRANK, E. G., J. HAUSER, A. S. LEVINE and R. WOODGATE, 1993 Targeting of the UmuD, UmuD′, and MucA′ mutagenesis proteins to DNA by RecA protein. Proc. Natl. Acad. Sci. USA 90: 8169-8173.
9. FRIEDBERG, E. C., 1988 Deoxyribonucleic acid repair in the yeast Saccharomyces cerevisiae. Microbiol. Rev. 52: 70-102.
10. GIETZ, D., A. ST. JEAN, R. A. WOODS and R. H. SCHIESTL, 1992 Improved method for high efficiency transformation of intact yeast cells. Nucleic Acids Res. 20: 1425.
11. HALL, B. G., 1992 Selection-induced mutations occur in yeast. Proc. Natl. Acad. Sci. USA 89: 4300-4303.
12. HARRIS, R. S., S. LONGERICH and S. M. ROSENBERG, 1994 Recombination in adaptive mutation. Science 264: 258-260.
13. HAYNES, R. H., and B. A. KUNZ, 1981 DNA repair and mutagenesis in yeast, pp. 371-414 in The Molecular Biology of the Yeast Saccharomyces. Life Cycle and Inheritance, edited by J. N. STRAIHERN, E. W. JONES and J. R. BROACH. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.
14. JENSEN, R., and I. HERSKOWITZ, 1984 Directionality and regulation of cassette substitution in yeast. Cold Spring Harbor Symp. Quant. Biol. 49: 97-104.
15. JOHNSON, L. M., M. SNYDER, L. M. S. CHANG, R. W. DAVIS and J. L. CAMPBELL, 1985 Isolation of the gene encoding yeast DNA polymerase I. Cell 43: 369-377.
16. KEENEY, S., C. N. GIROUX and N. KLECKNER, 1997 Meiosis-specific DNA double-strand breaks are catalyzed by Spoil, a member of a widely conserved protein family. Cell 88: 375-384.
17. KUNKEL, T. S., M. S. RESNICK and D. A. GORDENIN, 1997 Mutator specificity and disease: looking over the FENce. Cell 88: 155-158.
18. LARIMER, F. W., J. R. PERRY and A. A. HARDIGREE, 1989 The REV1 gene of Saccharomyces cerevisiae: isolation, sequence and functional analysis. J. Bacteriol. 171: 230-237.
19. LAWRENCE, C. W., and R. B. CHRISTENSEN, 1979 Ultraviolet-induced reversion of ultraviolet-induced reversion of cyc1 alleles in radiation-sensitive strains of yeast. III. rev 3 mutant strains. Genetics 92: 397-408.
20. LAWRENCE, C. W., T. O'BRIEN and J. BOND, 1984 UV-induced reversion of his4 frameshift mutations in rad6, rev1, and rev3 mutants of yeast. Mol. Gen. Genet. 195: 487-490.
21. LAWRENCE, C. W., G. DAS and R. B. CHRISTENSEN, 1985 UV and chemical mutagenesis in rev7 mutants of yeast. Mol. Gen. Genet. 200: 80-85.
22. LEACH, F. S., N. C. NICOLAIDES, N. PAPADOPOULOS, B. LIU, J. JEN et al., 1993 Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer. Cell 75: 1215-1225.
23. LEMONTT, J. F., 1971 Mutations of yeast defective in mutation induced by ultraviolet light. Genetics 195: 487-490.
24. LU, Y., T. HALL, L. S. GAY and J. E. DONELSON, 1993 Point mutations are associated with a gene duplication leading to the bloodstream reexpression of a trypanosome metacyclic VSG. Cell 72: 397-406.
25. LU, Y., C. M. ALARCON, T. HALL, L. V. REDDY and J. E. DONELSON, 1994 A strand bias occurs in point mutations associated with variant surface glycoprotein gene conversion in Trypanosoma rhodesiense. Mol. Cell. Biol. 14: 3971-3980.
26. MAGNI, G. E., and R. C. VON BORSTEL, 1963 Different rates of spontaneous mutation during mitosis and meiosis in yeast. Genetics 47: 1097-1108.
27. MCGILL, C. B., B. K. SHAFER, D. R. HIGGINS and J. N. STRATHERN, 1990 Analysis of interchromosomal mitotic recombination. Curr. Genet. 18: 29-39.
28. MCGILL, C. B., B. K. SHAFER, L. K. DERR and J. N. STRATHERN, 1993 Recombination initiated by double-strand-breaks. Curr. Genet. 23: 305-314.
29. MORRISON, A., H. ARAKI, A. B. CLARK, R. K. HAMATAKE and A. SUGINO, 1990 A third essential DNA polymerase in S. cerevisiae. Cell 62: 1143-1151.
30. MORRISON, A., R. B. CHRISTENSEN, J. ALLEY, A. K. BECK, E. G. BERNSTINE et al., 1989 REV3, a Saccharomyces cerevisiae gene whose function is required for induced mutagenesis, is predicted to encode a nonessential DNA polymerase. J. Bacteriol. 171: 5659-5667.
31. MORRISON, A., and A. SUGINO, 1994 The 3′ → 5′ exonucleases of both DNA polymerases δ and ∈ participate in correcting errors of DNA replication in Saccharomyces cerevisiae. Mol. Gen. Genet. 242: 289-296.
32. NELSON, J. R., C. W. LAWRENCE and D. C. HINKLE, 1996 Thyminethymine dimer bypass by yeast DNA polymerase ζ. Science 272: 1646-1649.
33. NEUBERGER, M. S., and C. MILSTEIN, 1995 Somatic hypermutation. Curr. Opin. Immunol. 7: 248-254.
34. + tumor cells. Cell 75: 1227-1236.
35. QUAH, S-K., R. C. VON BORSTEL and P. J. HASTINGS, 1980 The origin of spontaneous mutation in Saccharomyces cerevisiae. Genetics 96: 819-839.
36. RAJAGOPALAN, M., C. LU, R. WOODGATE, M. O'DONNELL, M .F. GOODMAN et al., 1992 Activity of the purified mutagenesis proteins UmuC, UmuD′, and RecA in replicative bypass of an abasic DNA lesion by DNA polymerase III. Proc. Natl. Acad. Sci. USA 89: 10777-10781.
37. RIPLEY, L. S., and N. B. SHOEMAKER, 1983 A major role for bacteriophage T4 DNA polymerase in frameshift mutagenesis. Genetics 103: 353-366.
38. RIPLEY, L. S., B. W. GLICKMAN and N. B. SHOEMAKER, 1983 Mutator vs. antimutator activity of a T4 DNA polymerase mutant distinguishes two different frameshifting mechanisms. Mol. Gen. Genet. 189: 113-117.
39. ROCHE, H., R. D. GIETZ and B. A. KUNZ, 1994 Specificity of the yeast rev3Δ antimutator and REV3 dependency of the mutator resulting from a defect (rad1Δ) in nucleotide excision repair. Genetics 137: 637-646.
40. SHERMAN, F., G. R. FINK and J. B. HICKS, 1986 Laboratory Course Manual for Methods in Yeast Genetics. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.
41. SINGHAL, R. K., D. C. HINKLE and C. W. LAWRENCE, 1992 The REV3 gene of Saccharomyces cerevisiae is transcriptionally regulated more like a repair gene than one encoding a DNA polymerase. Mol. Gen. Genet. 236: 17-24.
42. STEELE, D. F., and S. JINKS-ROBERTSON, 1992 An examination of adaptive reversion in Saccharomyces cerevisiae. Genetics 132: 9-21.
43. STRATHERN. J. N., B. K. SHAFER and C. B. MCGILL, 1995 DNA synthesis errors associated with double-strand-break repair. Genetics 140: 965-972.
44. SZOSTAK, J. W., T. L. ORR-WEAVER, R. J. ROTHSTEIN and F. W. STAHL, 1983 The double-strand break repair model for recombination. Cell 33: 25-35.
45. WANG, Z., X. Wu and E. C. FRIEDBERG, 1993 DNA repair synthesis during base excision repair in vitro is catalyzed by DNA polymerase ∈ and is influenced by DNA polymerases α and δ in Saccharomyces cerevisiae. Mol. Cell Biol. 13: 1051-1058.