CD30 is a CD40-inducible molecule that negatively regulates CD40- mediated immunoglobulin class switching in non-antigen-selected human B cells

Immunity

Volumn 9, Issue 2, 1998, Pages 247-256

  Cerutti, Andrea ^a   Schaffer, Andrés ^a,b   Shah, Shefali ^a   Zan, Hong ^a   Liou, Hsiou Chi ^a   Goodwin, Raymond G ^c   Casali, Paolo ^a,b  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b Weill Cornell Medical Center   (United States)

^c AMGEN INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD30 ANTIGEN; CD40 ANTIGEN; IMMUNOGLOBULIN CLASS;

ANTIGEN EXPRESSION; ARTICLE; B LYMPHOCYTE DIFFERENTIATION; FLOW CYTOMETRY; GENE REARRANGEMENT; GERMINAL CENTER; HUMAN; HUMAN CELL; LYMPHOCYTE PROLIFERATION; PRIORITY JOURNAL; TRANSCRIPTION REGULATION;

EID: 0032142893     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-7613(00)80607-X     Document Type: Article

References (47)

1. Ansieau, S., Scheffrahn, I., Mosialos, G., Brand, H., Duyster, J., Kaye, K., Harada, J., Dougall, B., Hubinger, G., Kieff, E., et al. (1996). Tumor necrosis factor receptor associated (TRAF)-1, TRAF-2, and TRAF-3 interact in vivo with the CD30 cytoplasmic domain; TRAF-2 mediates CD30-induced nuclear factor K B activation. Proc. Natl. Acad. Sci. USA 93, 14053-14058.
2. Armitage, R.J., Sato, AT., Macduff, B.M., Clifford, K.N., Alpert, A.R., Smith, A., and Fanslow, W.C. (1992). Identification of a source of biologically active CD40 ligand. Eur. J. Immunol. 22, 2071-2076.
3. Aruffo, A., Farrington, M., Hollenbaugh, D., Li, X., Milatovich, A., Nonoyama, S., Bajorath, J., Grosmaire, L.S., Stenkamp, R., Nebauer, M., Roberts, R.L., et al. (1993). The CD40 ligand, gp39, is defective in activated T cells from patients with X-linked hyper IgM syndrome. Cell 72, 291-300.
4. + B cell line. J. Immunol. 160, 2145-2157.
5. Choe, J., Kim, H.S., Zhang, X., Armitage, R.J., and Choi, Y.S. (1996). Cellular and molecular factors that regulate the differentiation and apoptosis of germinal center B cells. Anti-lg down-regulates Fas expression on CD40 ligand-stimulated germinal center B cells and inhibits Fas-mediated apoptosis. J. Immunol. 157, 1006-1016.
6. Clark, E.A., and Ledbetter, J.A. (1994). How B and T cells talk to each other. Nature 367, 425-429.
7. Del Prete, G., De Carli, M., D' Elios, M.M., Daniel, K.C., Almerigogna, F., Alderson, M., Smith, C.A., Thomas, E., and Romagnani, S. (1995). CD30-mediated signaling promotes the development of human T helper type 2-like T cells. J. Exp. Med. 182, 1655-1661.
8. Duckett, C.S., and Thompson, C.B. (1997). CD30-dependent degradation of TRAF-2: implications for negative regulation of TRAF signaling and the control of cell survival. Genes Dev. 11, 2810-2821.
9. Dürkop, H., Latza, U., Hummel, M., Eitelbach, F., Seed, B., and Stein, H. (1992). Molecular cloning and expression of a new member of the nerve growth factor receptor family that is characteristic for Hodgkin's disease. Cell 68, 421-427.
10. Endo, T.A, Masuhara, M., Yokkouchi, M., Suzuki, R., Sakamoto, H., Mitsui, K., Matsumoto, A., Tanimura, S., Ohtsubo, M., Misawa, H., et al. (1997). A new protein containing a SH2 domain that inhibits Jak kinases. Nature 387, 921-924.
11. + T cell responses. Immunol. Today 17, 410-414.
12. Gruss, H.-J., Ulrich, D., Braddy, S., Armitage, R.J., and Dower, S.K. (1995). Recombinant CD30 ligand and CD40 ligand share common biological activities on Hodgkin and Reed-Sterberg cells. Eur. J. Ilmmunol. 25, 2083-2089.
13. Hanissian, S.H., and Geha, R. (1997). Jak3 is associated with CD40 and is critical for CD40 induction of gene expression in B cells. Immunity 6, 379-387.
14. Hodgkin, P.D., Lee, J.H., and Lyons, A.B. (1996). B cell differentiation and isotype switching is related to division cycle number. J. Exp. Med. 184, 277-281.
15. Jacquot, S., Kobata, T., Iwata, S., Morimoto, C., and Schlossman, S.F. (1997). CD154/CD40 and CD70/CD27 interactions have different and sequential functions in T cell-dependent B cell responses: enhancement of plasma cell differentiation by CD27 signaling. J. Immunol. 159, 2652-2657.
16. Jumper, M.D., Splawski, J.B., Lipsky, P.E., and Meek, K. (1993). Ligation of CD40 induces sterile transcripts of multiple Ig H chain isotypes in human B cells. J. Immunol. 152, 438-445.
17. Jumper, M.D., Nishioka, Y., Davies, L.S., Lipsky, P.E., and Meek, K. (1995). Regulation of human B cell function by recombinant CD40 ligand and other TNF-related ligands. J. Immunol. 155, 2369-2378.
18. Jumper, M.D., Fujita, K., Lipsky, P.L., and Meek, K. (1996). A CD30 responsive element in the germline e promoter that is distinct from and inhibitory to the CD40 responsive element. Mol. Immunol. 33, 965-972.
19. Kehry, M.R. (1996). CD40-mediated signaling in B cells. Balancing cell survival, growth, and death. J. Immunol. 156, 2345-2348.
20. Kuhné, M.R., Robbins, M., Hambor, J.E., Mackey, M.F., Kosaka, Y., Nishimura, T., Gigley, J.P., Noelle, R.J., and Calderhead, D.M. (1997).
21. Assembly and regulation of the CD40 receptor complex in human B cells. J. Exp. Med. 186, 337-342.
22. KB activation. J. Exp. Med. 185, 1275-1285.
23. INK4c and IL-6. Immunity 6, 47-56.
24. Mueller, C.G.F., Rissoan, M.F., Salinas, B., Ait-Yahia, S., Ravel, O., Bridon, J.M., Brière, F., Lebecque, S., and Liu, Y.J. (1997). Polymerase chain reaction selects a novel disintegrin proteinasefrom CD40-activated germinal center dendritic cells. J. Exp. Med. 29, 655-663.
25. Naka, T., Narazaki, M., Hirata, M., Matsumoto, T., Minamoto, S., Aono, A., Nishimoto, N., Kajita, T., Taga, T., Yoshizaki, K., et al. (1997). Structure and function of a new STAT-induced STAT inhibitor. Nature 387, 924-929.
26. O'Rourke, L., Tooze, R., and Fearon, D. (1997). Co-receptors of B lymphocytes. Curr. Opin. Immunol. 9, 324-329.
27. Ranheim, E.A., and Kipps, T.J. (1993). Activated T cells induce expression of B7/BB1 on normal or leukemic B cells through a CD40-dependent signal. J. Exp. Med. 177, 925-935.
28. KB kinase. Cell 90, 373-383.
29. KB by TNF receptor 2 and CD40. Science 269, 1424-1427.
30. Rothe, M., Xiong, J, Shu, H.-B., Williamson, K., Goddard, A., and Goeddel D.V. (1996). I-TRAF is a novel TRAF-interacting protein that regulates TRAF-mediated signal transduction. Proc. Natl. Acad. Sci. USA 93, 8241-8246.
31. Schaffer, A., Cerutti, A., Zan, H., Max, E.E., and Casali, P. (1998). The ECS-lγ3 sequence upstream of the human immunoglobulin heavy chain Sγ3 region is a functional promoter. Synergistic activation by CD40 ligand and IL-4 via distinct cis regulatory elements. FASEB J. 12, A1058.
32. Schattner, E.J., Elkon, K.B., Yoo, D.H., Tumang, J., Krammer, P.M., Crow, M.K., and Friedman, S.M. (1995). CD40 ligation induces Apo-1/Fas expression on human B lymphocytes and facilitatesapoptosis through the Apo-1/Fas pathway. J. Exp. Med. 182, 1557-1565.
33. Schwarting, R., Gerdes, J., Dürkop, H., Falini, B., Pileri, S., and Stein, H. (1989). BER-H2: a new anti-Ki-1 (CD30) monoclonal antibody directed at a formol-resistant epitope. Blood 74, 1678-1689.
34. Smith, C.A., Gruss, H.J., Davis, T., Anderson, D., Farrah, T., Baker, E., Sutherland, G.R., Brannan, C.I., Copeland, N.G., Jenkins, N.A., et al. (1993). CD30 antigen, a marker for Hodgkin's lymphoma, is a receptor whose ligand defines an emerging family of cytokines with homology to TNF. Cell 73, 1349-1360.
35. Smith, C.A., Farrah, T., and Goodwin, R.G. (1994). The TNF receptor superfamily of cellular and viral proteins: activation, costimulation, and death. Cell 76, 959-962.
36. Song, H.Y., Rothe, M., and Goeddel, D.V. (1996). The tumor necrosis factor-inducible zinc finger protein A20 interacts with TRAF1/TRAF2 and inhibits NF-KB activation. Proc. Natl. Acad. Sci. USA 93, 6721-6725.
37. Stavnezer, J. (1996). Antibody class switching. Adv. Immunol. 61, 79-146.
38. Stein, H., Gerdes, J., Schwab, U., Lemke, H., Mason, D.Y., Ziegler, A., Schienle, W., and Diehl, W. (1982). Identification of Hodgkin and Sternberg-Reed cells as a unique cell type derived from a newly-detected small-cell population. Int. J. Cancer 30, 445-459.
39. Stein, H., Mason, D.Y., Gerdes, J., O'Connor, N., Wainscoat, J., Pallesen, G., Gatter, K., Falini, B., Delsol, G., Lemke, H., et al. (1985). The expression of the Hodgkin's disease associated antigen Ki-1 in reactive and neoplastic lymphoid tissue: evidence that Reed-Sternberg cells and histiocytic malignancies are derived from activated lymphoid cells. Blood 66, 848-858.
40. Stuber, E., Neurath, M., Calderhead, D., Fell, H.P., and Strober, W. (1995). Cross-linking of OX40 ligand, a member of the TNF/NGF cytokine family, induces proliferation and differentiation in murine splenic B cells. Immunity 2, 507-521.
41. Takai, T., Ono, M., Hikida, M., Ohmori, H., and Ravetch, J.V. (1996). Augmented humoral and anaphylactic responses in FcγRII-deficient mice. Nature 379, 346-349.
42. Tivol, E.A., Borriello, F., Schweitzer, A.N., Lynch, W.P., Bluestone, J.A., and Sharpe, A.H. (1995). Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4. Immunity 3, 541-547.
43. Van Kooten, C., and Banchereau, J. (1996). CD40-CD40 ligand: a multifunctional receptor-ligand pair. Adv. Immunol. 61, 1-77.
44. Walunas, T.L., Baker, C.Y., and Bluestone, J.A. (1996). CTLA-4 ligation blocks CD28-dependent T cell activation. J. Exp. Med. 183, 2541-2550.
45. Yoshimoto, T., Okamura, H., Tagawa, Y.I., Iwakura, Y., and Nakanishi, K. (1997). Interleukin 18 together with interleukin 12 inhibits IgE production by induction of Interferon-γ production from activated B cells. Proc. Natl. Acad. Sci. USA 95, 3948-3953.
46. Zan, H., Cerutti, A., Dramitinos, P., Schaffer, A., and Casali, P. (1998a). CD40 engagement triggers switching to lgA1 and lgA2 in human B cells in the absence of other stimuli and through the induction of endogenous TGFβ. Evidence for TGFβ dependent but not IL-10-dependent direct Sμ-Sα and sequential Sμ-Sγ, Sγ-Sα DNA recombination. J. Immunol., in press.
47. Zan, H., Cerutti, A., Dramitinos, P., Schaffer, A., Li, Z., and Casali, P. (1998b). Induction of coordinated Ig somatic hypermutation and class switching in a human monoclonal model of germinal center B cell differentiation. FASEB J. 12, A1057.