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Volumn 36, Issue 1, 2003, Pages 120-127

Hypoxia-induced angiogenesis during carcinogenesis

Author keywords

Angiogenesis; HIF 1 ; Hypoxia

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1; HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 1BETA; OXYGEN; PROTEIN; PROTEIN JAB1; PROTEIN P300; PROTEIN P53; PROTEIN PVHL; PROTEIN SUBUNIT; TRANSCRIPTION FACTOR AP 1; UNCLASSIFIED DRUG; VASCULOTROPIN; DNA BINDING PROTEIN; ENDOTHELIAL CELL GROWTH FACTOR; HIF1A PROTEIN, HUMAN; LYMPHOKINE; NUCLEAR PROTEIN; SIGNAL PEPTIDE; TRANSCRIPTION FACTOR; VASCULOTROPIN A;

EID: 0037530130     PISSN: 12258687     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (156)

References (99)
  • 1
    • 0012270024 scopus 로고    scopus 로고
    • Regulation of placental vascular endothelial growth factor (VEGF) and placenta growth factor (PIGF) and soluble Flt-1 by oxygen-a review
    • Ahmed, A., Dunk, C., Ahmad, S. and Khaliq, A. (2000) Regulation of placental vascular endothelial growth factor (VEGF) and placenta growth factor (PIGF) and soluble Flt-1 by oxygen-a review. Placenta 21 Suppl. A, S16-S24.
    • (2000) Placenta , vol.21 , Issue.SUPPL. A
    • Ahmed, A.1    Dunk, C.2    Ahmad, S.3    Khaliq, A.4
  • 2
    • 0034011580 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factor in surgical specimens of hepatocellular carcinoma
    • An, F. Q., Matsuda, M., Fujii, H. and Matsumoto, Y. (2000) Expression of vascular endothelial growth factor in surgical specimens of hepatocellular carcinoma. J. Cancer Res. Clin. Oncol. 126, 153-160.
    • (2000) J. Cancer Res. Clin. Oncol. , vol.126 , pp. 153-160
    • An, F.Q.1    Matsuda, M.2    Fujii, H.3    Matsumoto, Y.4
  • 7
    • 0035794541 scopus 로고    scopus 로고
    • COP9 signalosome-specific phosphorylation targets p53 to degradation by the ubiquitin system
    • Bech-Otschir, D., Kraft, R., Huang, X., Henklein, P., Kapelari, B., Pollmann, C. and Dubiel, W. (2001) COP9 signalosome-specific phosphorylation targets p53 to degradation by the ubiquitin system. EMBO J. 20, 1630-1639.
    • (2001) EMBO J. , vol.20 , pp. 1630-1639
    • Bech-Otschir, D.1    Kraft, R.2    Huang, X.3    Henklein, P.4    Kapelari, B.5    Pollmann, C.6    Dubiel, W.7
  • 8
    • 0034531952 scopus 로고    scopus 로고
    • MAP kinases and hypoxia in the control of VEGF expression
    • Berra, E., Pages, G. and Pouyssegur, J. (2000) MAP kinases and hypoxia in the control of VEGF expression. Cancer Metastasis Rev. 19, 139-145.
    • (2000) Cancer Metastasis Rev. , vol.19 , pp. 139-145
    • Berra, E.1    Pages, G.2    Pouyssegur, J.3
  • 9
    • 0034904751 scopus 로고    scopus 로고
    • Hypoxia-inducible factor-1 alpha (HIF-1 alpha) escapes O(2)-driven proteasomal degradation irrespective of its subcellular localization: Nucleus or cytoplasm
    • Berra, E., Roux, D., Richard, D. E. and Pouyssegur, J. (2001) Hypoxia-inducible factor-1 alpha (HIF-1 alpha) escapes O(2)-driven proteasomal degradation irrespective of its subcellular localization: nucleus or cytoplasm. EMBO Rep. 2, 615-620.
    • (2001) EMBO Rep. , vol.2 , pp. 615-620
    • Berra, E.1    Roux, D.2    Richard, D.E.3    Pouyssegur, J.4
  • 10
    • 0032900610 scopus 로고    scopus 로고
    • Functional role of p35srj, a novel p300/CBP binding protein, during transactivation by HIF-1
    • Bhattacharya, S., Michels, C. L., Leung, M. K., Arany, Z. P., Kung, A. L. and Livingston, D. M. (1999) Functional role of p35srj, a novel p300/CBP binding protein, during transactivation by HIF-1. Genes Dev. 13, 64-75.
    • (1999) Genes Dev. , vol.13 , pp. 64-75
    • Bhattacharya, S.1    Michels, C.L.2    Leung, M.K.3    Arany, Z.P.4    Kung, A.L.5    Livingston, D.M.6
  • 11
    • 0032506542 scopus 로고    scopus 로고
    • Regulation of activity of the transcription factor GATA-1 by acetylation
    • Boyes, J., Byfield, P., Nakatani, Y. and Ogryzko, V. (1998) Regulation of activity of the transcription factor GATA-1 by acetylation. Nature 396, 594-598.
    • (1998) Nature , vol.396 , pp. 594-598
    • Boyes, J.1    Byfield, P.2    Nakatani, Y.3    Ogryzko, V.4
  • 12
    • 0035834409 scopus 로고    scopus 로고
    • A conserved family of prolyl-4-hydroxylases that modify HIF
    • Bruick, R. K. and McKnight, S. L. (2001) A conserved family of prolyl-4-hydroxylases that modify HIF. Science 294, 1337-1340.
    • (2001) Science , vol.294 , pp. 1337-1340
    • Bruick, R.K.1    McKnight, S.L.2
  • 13
    • 0029842459 scopus 로고    scopus 로고
    • Oxygen sensing and molecular adaptation to hypoxia
    • Bunn, H. F. and Poyton, R. O. (1996) Oxygen sensing and molecular adaptation to hypoxia. Physiol Rev. 76, 839-885.
    • (1996) Physiol Rev. , vol.76 , pp. 839-885
    • Bunn, H.F.1    Poyton, R.O.2
  • 14
    • 0034094342 scopus 로고    scopus 로고
    • The pathophysiology of the collateral circulation (arteriogenesis)
    • Buschmann, I. and Schaper, W. (2000) The pathophysiology of the collateral circulation (arteriogenesis). J. Pathol. 190, 338-342.
    • (2000) J. Pathol. , vol.190 , pp. 338-342
    • Buschmann, I.1    Schaper, W.2
  • 15
    • 0034100836 scopus 로고    scopus 로고
    • Hypoxia-inducible factor1 mediates the biological effects of oxygen on human trophoblast differentiation through TGFbeta (3)
    • Caniggia, I., Mostachfi, H., Winter, J., Gassmann, M., Lye, S. J., Kuliszewski, M. and Post, M. (2000) Hypoxia-inducible factor1 mediates the biological effects of oxygen on human trophoblast differentiation through TGFbeta (3). J. Clin. Invest. 105, 577-587.
    • (2000) J. Clin. Invest. , vol.105 , pp. 577-587
    • Caniggia, I.1    Mostachfi, H.2    Winter, J.3    Gassmann, M.4    Lye, S.J.5    Kuliszewski, M.6    Post, M.7
  • 16
    • 0029849637 scopus 로고    scopus 로고
    • In vivo angiogenic activity and hypoxia induction of heterodimers of placenta growth factor/vascular endothelial growth factor
    • Cao, Y., Linden, P., Shima, D., Browne, F. and Folkman, J. (1996) In vivo angiogenic activity and hypoxia induction of heterodimers of placenta growth factor/vascular endothelial growth factor. J. Clin. Invest. 98, 2507-2511.
    • (1996) J. Clin. Invest. , vol.98 , pp. 2507-2511
    • Cao, Y.1    Linden, P.2    Shima, D.3    Browne, F.4    Folkman, J.5
  • 18
    • 0034648765 scopus 로고    scopus 로고
    • Angiogenesis in cancer and other diseases
    • Carmeliet, P. and Jain, R. K. (2000) Angiogenesis in cancer and other diseases. Nature 407, 249-257.
    • (2000) Nature , vol.407 , pp. 249-257
    • Carmeliet, P.1    Jain, R.K.2
  • 19
    • 0033986948 scopus 로고    scopus 로고
    • Redox-regulated recruitment of the transcriptional co-activators CREB-binding protein and SRC-1 to hypoxia-inducible factor 1alpha
    • Carrero, P., Okamoto, K., Coumailleau, P., O'Brien, S., Tanaka, H. and Poellinger, L. (2000) Redox-regulated recruitment of the transcriptional co-activators CREB-binding protein and SRC-1 to hypoxia-inducible factor 1alpha. Mol. Cell Biol. 20, 402-415.
    • (2000) Mol. Cell Biol. , vol.20 , pp. 402-415
    • Carrero, P.1    Okamoto, K.2    Coumailleau, P.3    O'Brien, S.4    Tanaka, H.5    Poellinger, L.6
  • 23
    • 0035895737 scopus 로고    scopus 로고
    • Molecular mechanisms of blood vessel growth
    • Conway, E. M., Collen, D. and Carmeliet, P. (2001) Molecular mechanisms of blood vessel growth. Cardiovasc. Res. 49, 507-521.
    • (2001) Cardiovasc. Res. , vol.49 , pp. 507-521
    • Conway, E.M.1    Collen, D.2    Carmeliet, P.3
  • 24
    • 0032504165 scopus 로고    scopus 로고
    • Adrenomedullin gene expression is developmentally regulated and induced by hypoxia in rat ventricular cardiac myocytes
    • Cormier-Regard, S., Nguyen, S. V. and Claycomb, W. C. (1998) Adrenomedullin gene expression is developmentally regulated and induced by hypoxia in rat ventricular cardiac myocytes. J. Biol. Chem. 273, 17787-17792.
    • (1998) J. Biol. Chem. , vol.273 , pp. 17787-17792
    • Cormier-Regard, S.1    Nguyen, S.V.2    Claycomb, W.C.3
  • 25
    • 0030611360 scopus 로고    scopus 로고
    • Characterization of the alpha1B-adrenergic receptor gene promoter region and hypoxia regulatory elements in vascular smooth muscle
    • Eckhart, A. D., Yang, N., Xin, X. and Faber, J. E. (1997) Characterization of the alpha1B-adrenergic receptor gene promoter region and hypoxia regulatory elements in vascular smooth muscle. Proc. Natl. Acad. Sci. USA 94, 9487-9492.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 9487-9492
    • Eckhart, A.D.1    Yang, N.2    Xin, X.3    Faber, J.E.4
  • 26
    • 0033118983 scopus 로고    scopus 로고
    • Molecular mechanisms of transcription activation by HLF and HIF1alpha in response to hypoxia: Their stabilization and redox signal-induced interaction with CBP/p300
    • Ema, M., Hirota, K., Mimura, J., Abe, H., Yodoi, J., Sogawa, K., Poellinger, L. and Fujii-Kuriyama, Y. (1999) Molecular mechanisms of transcription activation by HLF and HIF1alpha in response to hypoxia: their stabilization and redox signal-induced interaction with CBP/p300. EMBO J. 18, 1905-1914.
    • (1999) EMBO J. , vol.18 , pp. 1905-1914
    • Ema, M.1    Hirota, K.2    Mimura, J.3    Abe, H.4    Yodoi, J.5    Sogawa, K.6    Poellinger, L.7    Fujii-Kuriyama, Y.8
  • 28
    • 0033566693 scopus 로고    scopus 로고
    • Reciprocal positive regulation of hypoxia-inducible factor 1alpha and insulin-like growth factor 2
    • Feldser, D., Agani, F., Iyer, N. V., Pak, B., Ferreira, G. and Semenza, G. L. (1999) Reciprocal positive regulation of hypoxia-inducible factor 1alpha and insulin-like growth factor 2. Cancer Res. 59, 3915-3918.
    • (1999) Cancer Res. , vol.59 , pp. 3915-3918
    • Feldser, D.1    Agani, F.2    Iyer, N.V.3    Pak, B.4    Ferreira, G.5    Semenza, G.L.6
  • 29
    • 0015008620 scopus 로고
    • Isolation of a tumor factor responsible or angiogenesis
    • Folkman, J., Merler, E., Abernathy, C. and Williams, G. (1971) Isolation of a tumor factor responsible or angiogenesis. J. Exp. Med. 133, 275-288.
    • (1971) J. Exp. Med. , vol.133 , pp. 275-288
    • Folkman, J.1    Merler, E.2    Abernathy, C.3    Williams, G.4
  • 30
    • 0030751493 scopus 로고    scopus 로고
    • Differential transcriptional regulation of the two vascular endothelial growth factor receptor genes. Fit-1, but not Flk-1/KDR, is up-regulated by hypoxia
    • Gerber, H. P., Condorelli, F., Park, J. and Ferrara, N. (1997) Differential transcriptional regulation of the two vascular endothelial growth factor receptor genes. Fit-1, but not Flk-1/KDR, is up-regulated by hypoxia. J. Biol. Chem. 272, 23659-23667.
    • (1997) J. Biol. Chem. , vol.272 , pp. 23659-23667
    • Gerber, H.P.1    Condorelli, F.2    Park, J.3    Ferrara, N.4
  • 31
    • 0035253409 scopus 로고    scopus 로고
    • Angiogenesis: The role of the microenvironment in flipping the switch
    • Giordano, F. J. and Johnson, R. S. (2001) Angiogenesis: the role of the microenvironment in flipping the switch. Curr. Opin. Genet. Dev. 11, 35-40.
    • (2001) Curr. Opin. Genet. Dev. , vol.11 , pp. 35-40
    • Giordano, F.J.1    Johnson, R.S.2
  • 32
    • 0028843411 scopus 로고
    • Regulation of angiogenic growth factor expression by hypoxia, transition metals, and chelating agents
    • Gleadle, J. M., Ebert, B. L., Firth, J. D. and Ratcliffe, P. J. (1995) Regulation of angiogenic growth factor expression by hypoxia, transition metals, and chelating agents. Am. J. Physiol 268, C1362-C1368.
    • (1995) Am. J. Physiol. , vol.268
    • Gleadle, J.M.1    Ebert, B.L.2    Firth, J.D.3    Ratcliffe, P.J.4
  • 33
    • 0030512608 scopus 로고    scopus 로고
    • Transgenic mouse models of tumor angiogenesis: The angiogenic switch, its molecular controls, and prospects for preclinical therapeutic models
    • Hanahan, D., Christofori, G., Naik, P. and Arbeit, J. (1996) Transgenic mouse models of tumor angiogenesis: the angiogenic switch, its molecular controls, and prospects for preclinical therapeutic models. Eur. J. Cancer 32A, 2386-2393.
    • (1996) Eur. J. Cancer , vol.32 A , pp. 2386-2393
    • Hanahan, D.1    Christofori, G.2    Naik, P.3    Arbeit, J.4
  • 34
    • 0033996775 scopus 로고    scopus 로고
    • Von Hippel-Lindan syndrome: Target for antivascular endothelial growth factor (VEGF) receptor therapy
    • Harris, A. L. (2000) von Hippel-Lindan syndrome: target for antivascular endothelial growth factor (VEGF) receptor therapy. Oncologist 5 Suppl. 1, 32-36.
    • (2000) Oncologist , vol.5 , Issue.SUPPL. 1 , pp. 32-36
    • Harris, A.L.1
  • 36
    • 0032576971 scopus 로고    scopus 로고
    • Hypoxia regulates expression of the endothelin-1 gene through a proximal hypoxia-inducible factor-1 binding site on the antisense strand
    • Hu, J., Discher, D. J., Bishopric, N. H. and Webster, K. A. (1998) Hypoxia regulates expression of the endothelin-1 gene through a proximal hypoxia-inducible factor-1 binding site on the antisense strand. Biochem. Biophys. Res. Commun. 245, 894-899.
    • (1998) Biochem. Biophys. Res. Commun. , vol.245 , pp. 894-899
    • Hu, J.1    Discher, D.J.2    Bishopric, N.H.3    Webster, K.A.4
  • 37
    • 0032493368 scopus 로고    scopus 로고
    • Regulation of hypoxia-inducible factor 1alpha is mediated by an O2-dependent degradation domain via the ubiquitin-proteasome pathway
    • Huang, L. E., Gu, J., Schau, M. and Bunn, H. F. (1998) Regulation of hypoxia-inducible factor 1alpha is mediated by an O2-dependent degradation domain via the ubiquitin-proteasome pathway. Proc. Natl. Acad. Sci. USA 95, 7987-7992.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 7987-7992
    • Huang, L.E.1    Gu, J.2    Schau, M.3    Bunn, H.F.4
  • 38
    • 0034494265 scopus 로고    scopus 로고
    • Genetic manipulation indicates that ARD1 is an essential N(infinity)-acetyltransferase in Trypanosoma brucei
    • Ingram, A. K., Cross, G. A. and Horn, D. (2000) Genetic manipulation indicates that ARD1 is an essential N(infinity)-acetyltransferase in Trypanosoma brucei. Mol. Biochem. Parasitol. 111, 309-317.
    • (2000) Mol. Biochem. Parasitol. , vol.111 , pp. 309-317
    • Ingram, A.K.1    Cross, G.A.2    Horn, D.3
  • 43
    • 0029944965 scopus 로고    scopus 로고
    • Dimerization, DNA binding, and transactivation properties of hypoxia-inducible factor 1
    • Jiang, B. H., Rue, E., Wang, G. L., Roe, R. and Semenza, G. L. (1996) Dimerization, DNA binding, and transactivation properties of hypoxia-inducible factor 1. J. Biol. Chem. 271, 17771-17778.
    • (1996) J. Biol. Chem. , vol.271 , pp. 17771-17778
    • Jiang, B.H.1    Rue, E.2    Wang, G.L.3    Roe, R.4    Semenza, G.L.5
  • 44
    • 0033772970 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF) and its effect on angiogenesis
    • Josko, J., Gwozdz, B., Jedrzejowska-Szypulka, H. and Hendryk, S. (2000) Vascular endothelial growth factor (VEGF) and its effect on angiogenesis. Med. Sci. Monit. 6, 1047-1052.
    • (2000) Med. Sci. Monit. , vol.6 , pp. 1047-1052
    • Josko, J.1    Gwozdz, B.2    Jedrzejowska-Szypulka, H.3    Hendryk, S.4
  • 45
    • 0033525830 scopus 로고    scopus 로고
    • Regulation of the hypoxia-inducible transcription factor 1alpha by the ubiquitin-proteasome pathway
    • Kallio, P. J., Wilson, W. J., O'Brien, S., Makino, Y. and Poellinger, L. (1999) Regulation of the hypoxia-inducible transcription factor 1alpha by the ubiquitin-proteasome pathway. J. Biol. Chem. 274, 6519-6525.
    • (1999) J. Biol. Chem. , vol.274 , pp. 6519-6525
    • Kallio, P.J.1    Wilson, W.J.2    O'Brien, S.3    Makino, Y.4    Poellinger, L.5
  • 46
    • 0034641615 scopus 로고    scopus 로고
    • Activation of HIF1alpha ubiquitination by a reconstituted von Hippel-Lindau (VHL) tumor suppressor complex
    • Kamura, T., Sato, S., Iwai, K., Czyzyk-Krzeska, M., Conaway, R.C. and Conaway, J.W. (2000) Activation of HIF1alpha ubiquitination by a reconstituted von Hippel-Lindau (VHL) tumor suppressor complex. Proc. Natl. Acad. Sci. USA 97, 10430-10435.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 10430-10435
    • Kamura, T.1    Sato, S.2    Iwai, K.3    Czyzyk-Krzeska, M.4    Conaway, R.C.5    Conaway, J.W.6
  • 47
    • 0032795850 scopus 로고    scopus 로고
    • Induction of the plasminogen activator inhibitor-1 gene expression by mild hypoxia via a hypoxia response element binding the hypoxia-inducible factor-I in rat hepatocytes
    • Kietzmann, T., Roth, U. and Jungermann, K. (1999) Induction of the plasminogen activator inhibitor-1 gene expression by mild hypoxia via a hypoxia response element binding the hypoxia-inducible factor-I in rat hepatocytes. Blood 94, 4177-4185.
    • (1999) Blood , vol.94 , pp. 4177-4185
    • Kietzmann, T.1    Roth, U.2    Jungermann, K.3
  • 48
    • 0031974197 scopus 로고    scopus 로고
    • Insulin-like growth factor II induced by hypoxia may contribute to angiogenesis of human hepatocellular carcinoma
    • Kim, K. W., Bae, S. K., Lee, O. H., Bae, M. H., Lee, M. J. and Park, B. C. (1998) Insulin-like growth factor II induced by hypoxia may contribute to angiogenesis of human hepatocellular carcinoma. Cancer Res. 58, 348-351.
    • (1998) Cancer Res. , vol.58 , pp. 348-351
    • Kim, K.W.1    Bae, S.K.2    Lee, O.H.3    Bae, M.H.4    Lee, M.J.5    Park, B.C.6
  • 49
    • 0033000990 scopus 로고    scopus 로고
    • Histone acetylases and deacetylases in cell proliferation
    • Kouzarides, T. (1999) Histone acetylases and deacetylases in cell proliferation. Curr. Opin. Genet. Dev. 9, 40-48.
    • (1999) Curr. Opin. Genet. Dev. , vol.9 , pp. 40-48
    • Kouzarides, T.1
  • 50
    • 0034654011 scopus 로고    scopus 로고
    • Acetylation: A regulatory modification to rival phosphorylation?
    • Kouzarides, T. (2000) Acetylation: a regulatory modification to rival phosphorylation? EMBO J. 19, 1176-1179.
    • (2000) EMBO J. , vol.19 , pp. 1176-1179
    • Kouzarides, T.1
  • 51
    • 0037097861 scopus 로고    scopus 로고
    • FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor
    • Lando, D., Peet, D. J., Gorman, J. J., Whelan, D. A., Whitelaw, M. L. and Bruick, R. K. (2002a) FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor. Genes Dev. 16, 1466-1471.
    • (2002) Genes Dev. , vol.16 , pp. 1466-1471
    • Lando, D.1    Peet, D.J.2    Gorman, J.J.3    Whelan, D.A.4    Whitelaw, M.L.5    Bruick, R.K.6
  • 52
    • 0036469038 scopus 로고    scopus 로고
    • Asparagine hydroxylation of the HIF transactivation domain a hypoxic switch
    • Lando, D., Peet, D. J., Whelan, D. A., Gorman, J. J. and Whitelaw, M. L. (2002b) Asparagine hydroxylation of the HIF transactivation domain a hypoxic switch. Science 295, 858-861.
    • (2002) Science , vol.295 , pp. 858-861
    • Lando, D.1    Peet, D.J.2    Whelan, D.A.3    Gorman, J.J.4    Whitelaw, M.L.5
  • 53
    • 0035012605 scopus 로고    scopus 로고
    • HER2 (neu) signaling increases the rate of hypoxia-inducible factor 1alpha (HIF-1alpha) synthesis: Novel mechanism for HIF-1-mediated vascular endothelial growth factor expression
    • Laughner, E., Taghavi, P., Chiles, K., Mahon, P. C. and Semenza, G. L. (2001) HER2 (neu) signaling increases the rate of hypoxia-inducible factor 1alpha (HIF-1alpha) synthesis: novel mechanism for HIF-1-mediated vascular endothelial growth factor expression. Mol. Cell Biol. 21, 3995-4004.
    • (2001) Mol. Cell Biol. , vol.21 , pp. 3995-4004
    • Laughner, E.1    Taghavi, P.2    Chiles, K.3    Mahon, P.C.4    Semenza, G.L.5
  • 55
    • 0031041377 scopus 로고    scopus 로고
    • Hypoxia-inducible factor-1 mediates transcriptional activation of the heine oxygenase-1 gene in response to hypoxia
    • Lee, P. J., Jiang, B. H., Chin, B. Y., Iyer, N. V., Alam, J., Semenza, G. L. and Choi, A. M. (1997) Hypoxia-inducible factor-1 mediates transcriptional activation of the heine oxygenase-1 gene in response to hypoxia. J. Biol. Chem. 272, 5375-5381.
    • (1997) J. Biol. Chem. , vol.272 , pp. 5375-5381
    • Lee, P.J.1    Jiang, B.H.2    Chin, B.Y.3    Iyer, N.V.4    Alam, J.5    Semenza, G.L.6    Choi, A.M.7
  • 56
    • 0035053713 scopus 로고    scopus 로고
    • The Ets family contains transcriptional activators and repressors involved in angiogenesis
    • Lelievre, E., Lionneton, F., Soncin, F. and Vandenbunder, B. (2001) The Ets family contains transcriptional activators and repressors involved in angiogenesis. Int. J. Biochem. Cell Biol. 33, 391-407.
    • (2001) Int. J. Biochem. Cell Biol. , vol.33 , pp. 391-407
    • Lelievre, E.1    Lionneton, F.2    Soncin, F.3    Vandenbunder, B.4
  • 57
    • 0000655498 scopus 로고    scopus 로고
    • Identification of a hypoxia response element in the transferrin receptor gene
    • Lok, C. N. and Ponka, P. (1999) Identification of a hypoxia response element in the transferrin receptor gene. J. Biol. Chem. 274, 24147-24152.
    • (1999) J. Biol. Chem. , vol.274 , pp. 24147-24152
    • Lok, C.N.1    Ponka, P.2
  • 58
    • 0035887011 scopus 로고    scopus 로고
    • FIH-1: A novel protein that interacts with HIF-1alpha and VHL to mediate repression of HIF-1 transcriptional activity
    • Mahon, P. C., Hirota, K. and Semenza, G. L. (2001) FIH-1: a novel protein that interacts with HIF-1alpha and VHL to mediate repression of HIF-1 transcriptional activity. Genes Dev. 15, 2675-2686.
    • (2001) Genes Dev. , vol.15 , pp. 2675-2686
    • Mahon, P.C.1    Hirota, K.2    Semenza, G.L.3
  • 60
    • 0035903468 scopus 로고    scopus 로고
    • Independent function of two destruction domains in hypoxia-inducible factor-alpha chains activated by prolyl hydroxylation
    • Masson, N., Willam, C., Maxwell, P. H., Pugh, C. W. and Ratcliffe, P. J. (2001) Independent function of two destruction domains in hypoxia-inducible factor-alpha chains activated by prolyl hydroxylation. EMBO J. 20, 5197-5206.
    • (2001) EMBO J. , vol.20 , pp. 5197-5206
    • Masson, N.1    Willam, C.2    Maxwell, P.H.3    Pugh, C.W.4    Ratcliffe, P.J.5
  • 62
    • 0028786601 scopus 로고
    • A hypoxia-responsive element mediates a novel pathway of activation of the inducible nitric oxide synthase promoter
    • Melillo, G., Musso, T., Sica, A., Taylor, L. S., Cox, G. W. and Varesio, L. (1995) A hypoxia-responsive element mediates a novel pathway of activation of the inducible nitric oxide synthase promoter. J. Exp. Med. 182, 1683-1693.
    • (1995) J. Exp. Med. , vol.182 , pp. 1683-1693
    • Melillo, G.1    Musso, T.2    Sica, A.3    Taylor, L.S.4    Cox, G.W.5    Varesio, L.6
  • 63
    • 0035478294 scopus 로고    scopus 로고
    • Transduction pathways involved in Hypoxia-Inducible Factor-1 phosphorylation and activation
    • Minet, E., Michel, G., Mottet, D., Raes, M. and Michiels, C. (2001) Transduction pathways involved in Hypoxia-Inducible Factor-1 phosphorylation and activation. Free Radic. Biol. Med. 31, 847-855.
    • (2001) Free Radic. Biol. Med. , vol.31 , pp. 847-855
    • Minet, E.1    Michel, G.2    Mottet, D.3    Raes, M.4    Michiels, C.5
  • 65
    • 0034647742 scopus 로고    scopus 로고
    • Role of hypoxia-inducible factor-1 in transcriptional activation of ceruloplasmin by iron deficiency
    • Mukhopadhyay, C. K., Mazumder, B. and Fox, P. L. (2000) Role of hypoxia-inducible factor-1 in transcriptional activation of ceruloplasmin by iron deficiency. J. Biol. Chem. 275, 21048-21054.
    • (2000) J. Biol. Chem. , vol.275 , pp. 21048-21054
    • Mukhopadhyay, C.K.1    Mazumder, B.2    Fox, P.L.3
  • 66
    • 0032907687 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF) and its receptors
    • Neufeld, G., Cohen, T., Gengrinovitch, S. and Poltorak, Z. (1999) Vascular endothelial growth factor (VEGF) and its receptors. FASEB J. 13, 9-22.
    • (1999) FASEB J. , vol.13 , pp. 9-22
    • Neufeld, G.1    Cohen, T.2    Gengrinovitch, S.3    Poltorak, Z.4
  • 68
    • 0033776536 scopus 로고    scopus 로고
    • Ubiquitination of hypoxia-inducible factor requires direct binding to the beta-domain of the von Hippel-Lindau protein
    • Ohh, M., Park, C. W., Ivan, M., Hoffman, M. A., Kim, T. Y., Huang, L. E., Pavletich, N., Chau, V. and Kaelin, W. G. (2000) Ubiquitination of hypoxia-inducible factor requires direct binding to the beta-domain of the von Hippel-Lindau protein. Nature Cell Biol. 2, 423-427.
    • (2000) Nature Cell Biol. , vol.2 , pp. 423-427
    • Ohh, M.1    Park, C.W.2    Ivan, M.3    Hoffman, M.A.4    Kim, T.Y.5    Huang, L.E.6    Pavletich, N.7    Chau, V.8    Kaelin, W.G.9
  • 69
    • 0035941117 scopus 로고    scopus 로고
    • Hypoxia induces transcription factor ETS-1 via the activity of hypoxia-inducible factor-1
    • Oikawa, M., Abe, M., Kurosawa, H., Hida, W., Shirato, K. and Sato, Y. (2001) Hypoxia induces transcription factor ETS-1 via the activity of hypoxia-inducible factor-1. Biochem. Biophys. Res. Commun. 289, 39-43.
    • (2001) Biochem. Biophys. Res. Commun. , vol.289 , pp. 39-43
    • Oikawa, M.1    Abe, M.2    Kurosawa, H.3    Hida, W.4    Shirato, K.5    Sato, Y.6
  • 70
    • 0031888729 scopus 로고    scopus 로고
    • Hypoxia induces type II NOS gene expression in pulmonary artery endothelial cells via HIF-1
    • Palmer, L. A., Semenza, G. L., Stoler, M. H. and Johns, R. A. (1998) Hypoxia induces type II NOS gene expression in pulmonary artery endothelial cells via HIF-1. Am. J. Physiol 274, L212-L219.
    • (1998) Am. J. Physiol. , vol.274
    • Palmer, L.A.1    Semenza, G.L.2    Stoler, M.H.3    Johns, R.A.4
  • 71
    • 0035621676 scopus 로고    scopus 로고
    • The IGFBP-1 mRNA experession in HepG2 cells is affected by inhibition of heme biosynthesis
    • Park, J. H., Park, T., Kim, H. Y. and Yang, Y. M. (2001) The IGFBP-1 mRNA experession in HepG2 cells is affected by inhibition of heme biosynthesis. J. Biochem. Mol. Biol. 34, 385-389.
    • (2001) J. Biochem. Mol. Biol. , vol.34 , pp. 385-389
    • Park, J.H.1    Park, T.2    Kim, H.Y.3    Yang, Y.M.4
  • 72
    • 0026605888 scopus 로고
    • ARD1 and NAT1 proteins form a complex that has N-terminal acetyltransferase activity
    • Park, E. C. and Szostak, J. W. (1992) ARD1 and NAT1 proteins form a complex that has N-terminal acetyltransferase activity. EMBO J. 11, 2087-2093.
    • (1992) EMBO J. , vol.11 , pp. 2087-2093
    • Park, E.C.1    Szostak, J.W.2
  • 74
    • 0030792094 scopus 로고    scopus 로고
    • Oxygen-regulated transferrin expression is mediated by hypoxia-inducible factor-1
    • Rolfs, A., Kvietikova, I., Gassmann, M. and Wenger, R. H. (1997) Oxygen-regulated transferrin expression is mediated by hypoxia-inducible factor-1. J. Biol. Chem. 272, 20055-20062.
    • (1997) J. Biol. Chem. , vol.272 , pp. 20055-20062
    • Rolfs, A.1    Kvietikova, I.2    Gassmann, M.3    Wenger, R.H.4
  • 75
    • 0036696165 scopus 로고    scopus 로고
    • Integrin-dependent regulation of gene expression in leukocytes
    • Rossetti, G., Collinge, M., Bender, J. R., Molteni, R. and Pardi, R. (2002) Integrin-dependent regulation of gene expression in leukocytes. Immunol. Rev. 186, 189-207.
    • (2002) Immunol. Rev. , vol.186 , pp. 189-207
    • Rossetti, G.1    Collinge, M.2    Bender, J.R.3    Molteni, R.4    Pardi, R.5
  • 76
    • 0037064141 scopus 로고    scopus 로고
    • Functional Analysis of Hypoxia-inducible Factor-1alpha-mediated Transactivation
    • Ruas, J. L., Poellinger, L. and Pereira, T. (2002) Functional Analysis of Hypoxia-inducible Factor-1alpha-mediated Transactivation. J. Biol. Chem. 277, 38723-38730.
    • (2002) J. Biol. Chem. , vol.277 , pp. 38723-38730
    • Ruas, J.L.1    Poellinger, L.2    Pereira, T.3
  • 77
    • 0032100732 scopus 로고    scopus 로고
    • HIF-1 alpha is required for solid tumor formation and embryonic vascularization
    • Ryan, H. E., Lo, J. and Johnson, R. S. (1998) HIF-1 alpha is required for solid tumor formation and embryonic vascularization. EMBO J. 17, 3005-3015.
    • (1998) EMBO J. , vol.17 , pp. 3005-3015
    • Ryan, H.E.1    Lo, J.2    Johnson, R.S.3
  • 78
    • 0031038419 scopus 로고    scopus 로고
    • Complex role of protein phosphorylation in gene activation by hypoxia
    • Salceda, S., Beck, I., Srinivas, V. and Caro, J. (1997) Complex role of protein phosphorylation in gene activation by hypoxia. Kidney Int. 51, 556-559.
    • (1997) Kidney Int. , vol.51 , pp. 556-559
    • Salceda, S.1    Beck, I.2    Srinivas, V.3    Caro, J.4
  • 79
    • 0030961006 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 1alpha (HIF-1alpha) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changes
    • Salceda, S. and Caro, J. (1997) Hypoxia-inducible factor 1alpha (HIF-1alpha) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changes. J. Biol. Chem. 272, 22642-22647.
    • (1997) J. Biol. Chem. , vol.272 , pp. 22642-22647
    • Salceda, S.1    Caro, J.2
  • 80
    • 0032712252 scopus 로고    scopus 로고
    • VEGF and therapeutic opportunities in cardiovascular diseases
    • Schaper, W. and Buschmann, I. (1999) VEGF and therapeutic opportunities in cardiovascular diseases. Curr. Opin. Biotechnol. 10, 541-543.
    • (1999) Curr. Opin. Biotechnol. , vol.10 , pp. 541-543
    • Schaper, W.1    Buschmann, I.2
  • 81
    • 0035745524 scopus 로고    scopus 로고
    • Arteriogenesis, a new concept of vascular adaptation in occlusive disease
    • Scholz, D., Cai, W.J. and Schaper, W. (2001) Arteriogenesis, a new concept of vascular adaptation in occlusive disease. Angiogenesis. 4, 247-257.
    • (2001) Angiogenesis , vol.4 , pp. 247-257
    • Scholz, D.1    Cai, W.J.2    Schaper, W.3
  • 83
    • 0033233243 scopus 로고    scopus 로고
    • Regulation of mammalian O2 homeostasis by hypoxia-inducible factor 1
    • Semenza, G. L. (1999) Regulation of mammalian O2 homeostasis by hypoxia-inducible factor 1. Annu. Rev. Cell Dev. Biol. 15, 551-578.
    • (1999) Annu. Rev. Cell Dev. Biol. , vol.15 , pp. 551-578
    • Semenza, G.L.1
  • 84
    • 0001572828 scopus 로고    scopus 로고
    • Oxygen-regulated transcription factors and their role in pulmonary disease
    • Semenza, G. L. (2000) Oxygen-regulated transcription factors and their role in pulmonary disease. Respir. Res. 1, 159-162.
    • (2000) Respir. Res. , vol.1 , pp. 159-162
    • Semenza, G.L.1
  • 85
    • 0036216692 scopus 로고    scopus 로고
    • HIF-1 and tumor progression: Pathophysiology and therapeutics
    • Semenza, G. L. (2002) HIF-1 and tumor progression: pathophysiology and therapeutics. Trends Mol. Med. 8, S62-S67.
    • (2002) Trends Mol. Med. , vol.8
    • Semenza, G.L.1
  • 86
    • 0034712939 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 1alpha protein expression is controlled by oxygen-regulated ubiquitination that is disrupted by deletions and missense mutations
    • Sutter, C. H., Laughner, E. and Semenza, G. L. (2000) Hypoxia-inducible factor 1alpha protein expression is controlled by oxygen-regulated ubiquitination that is disrupted by deletions and missense mutations. Proc. Natl. Acad. Sci. USA 97, 4748-4753.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 4748-4753
    • Sutter, C.H.1    Laughner, E.2    Semenza, G.L.3
  • 87
    • 0033588021 scopus 로고    scopus 로고
    • Transferrin receptor induction by hypoxia. HIF-1-mediated transcriptional activation and cell-specific posttranscriptional regulation
    • Tacchini, L., Bianchi, L., Bernelli-Zazzera, A. and Cairo, G. (1999) Transferrin receptor induction by hypoxia. HIF-1-mediated transcriptional activation and cell-specific posttranscriptional regulation. J. Biol. Chem. 274, 24142-24146.
    • (1999) J. Biol. Chem. , vol.274 , pp. 24142-24146
    • Tacchini, L.1    Bianchi, L.2    Bernelli-Zazzera, A.3    Cairo, G.4
  • 88
    • 0034816327 scopus 로고    scopus 로고
    • Hepatocyte growth factor signaling stimulates hypoxia inducible factor-1 (HIF-1) activity in HepG2 hepatoma cells
    • Tacchini, L., Dansi, P., Matteucci, E. and Desiderio, M. A. (2001) Hepatocyte growth factor signaling stimulates hypoxia inducible factor-1 (HIF-1) activity in HepG2 hepatoma cells. Carcinogenesis 22, 1363-1371.
    • (2001) Carcinogenesis , vol.22 , pp. 1363-1371
    • Tacchini, L.1    Dansi, P.2    Matteucci, E.3    Desiderio, M.A.4
  • 89
    • 0034640269 scopus 로고    scopus 로고
    • Hypoxic induction of prolyl 4-hydroxylase alpha (I) in cultured cells
    • Takahashi, Y., Takahashi, S., Shiga, Y., Yoshimi, T. and Miura, T. (2000) Hypoxic induction of prolyl 4-hydroxylase alpha (I) in cultured cells. J. Biol. Chem. 275, 14139-14146.
    • (2000) J. Biol. Chem. , vol.275 , pp. 14139-14146
    • Takahashi, Y.1    Takahashi, S.2    Shiga, Y.3    Yoshimi, T.4    Miura, T.5
  • 90
    • 0034663894 scopus 로고    scopus 로고
    • Mechanism of regulation of the hypoxia-inducible factor-1 alpha by the von Hippel-Lindan tumor suppressor protein
    • Tanimoto, K., Makino, Y., Pereira, T. and Poellinger, L. (2000) Mechanism of regulation of the hypoxia-inducible factor-1 alpha by the von Hippel-Lindan tumor suppressor protein. EMBO J. 19, 4298-4309.
    • (2000) EMBO J. , vol.19 , pp. 4298-4309
    • Tanimoto, K.1    Makino, Y.2    Pereira, T.3    Poellinger, L.4
  • 91
    • 0032544113 scopus 로고    scopus 로고
    • Hypoxia stimulates insulin-like growth factor binding protein 1 (IGFBP-1) gene expression in HepG2 cells: A possible model for IGFBP-1 expression in fetal hypoxia
    • Tazuke, S. I., Mazure, N. M., Sugawara, J., Carland, G., Faessen, G. H., Suen, L. F., Irwin, J.C., Powell, D. R., Giaccia, A. J. and Giudice, L. C. (1998) Hypoxia stimulates insulin-like growth factor binding protein 1 (IGFBP-1) gene expression in HepG2 cells: a possible model for IGFBP-1 expression in fetal hypoxia. Proc. Natl. Acad. Sci. USA 95, 10188-10193.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 10188-10193
    • Tazuke, S.I.1    Mazure, N.M.2    Sugawara, J.3    Carland, G.4    Faessen, G.H.5    Suen, L.F.6    Irwin, J.C.7    Powell, D.R.8    Giaccia, A.J.9    Giudice, L.C.10
  • 92
    • 0033545636 scopus 로고    scopus 로고
    • Degradation of the cyclin-dependent-kinase inhibitor p27Kip1 is instigated by Jab1
    • Tomoda, K., Kubota, Y. and Kato, J. (1999) Degradation of the cyclin-dependent-kinase inhibitor p27Kip1 is instigated by Jab1. Nature 398, 160-165.
    • (1999) Nature , vol.398 , pp. 160-165
    • Tomoda, K.1    Kubota, Y.2    Kato, J.3
  • 93
    • 0028222543 scopus 로고
    • Isolation of new genes in distal Xq28: Transcriptional map and identification of a human homologue of the ARD1 N-acetyl transferase of Saccharomyces cerevisiae
    • Tribioli, C., Mancini, M., Plassart, E., Bione, S., Rivella, S., Sala, C., Torri, G. and Toniolo, D. (1994) Isolation of new genes in distal Xq28: transcriptional map and identification of a human homologue of the ARD1 N-acetyl transferase of Saccharomyces cerevisiae. Human Mol. Genet. 3, 1061-1067.
    • (1994) Human Mol. Genet. , vol.3 , pp. 1061-1067
    • Tribioli, C.1    Mancini, M.2    Plassart, E.3    Bione, S.4    Rivella, S.5    Sala, C.6    Torri, G.7    Toniolo, D.8
  • 94
    • 0032979096 scopus 로고    scopus 로고
    • Regulation of angiogenesis in human hepatomas: Possible involvement of p53-inducible inhibitor of vascular endothelial cell proliferation
    • Tsukamoto, A., Kaneko, Y., Yoshida, T., Ichinose, M. and Kimura, S. (1999) Regulation of angiogenesis in human hepatomas: possible involvement of p53-inducible inhibitor of vascular endothelial cell proliferation. Cancer Lett. 141, 79-84.
    • (1999) Cancer Lett. , vol.141 , pp. 79-84
    • Tsukamoto, A.1    Kaneko, Y.2    Yoshida, T.3    Ichinose, M.4    Kimura, S.5
  • 95
    • 0027210562 scopus 로고
    • General involvement of hypoxia-inducible factor 1 in transcriptional response to hypoxia
    • Wang, G. L. and Semenza, G. L. (1993) General involvement of hypoxia-inducible factor 1 in transcriptional response to hypoxia. Proc. Natl. Acad. Sci. USA 90, 4304-4308.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 4304-4308
    • Wang, G.L.1    Semenza, G.L.2
  • 96
    • 0032478823 scopus 로고    scopus 로고
    • Selection and analysis of a mutant cell line defective in the hypoxia-inducible factor-1 alpha-subunit (HIF-1alpha). Characterization of hif-1alpha-dependent and -independent hypoxia-inducible gene expression
    • Wood, S. M., Wiesener, M. S., Yeates, K. M., Okada, N., Pugh, C. W., Maxwell, P. H. and Ratcliffe, P. J. (1998) Selection and analysis of a mutant cell line defective in the hypoxia-inducible factor-1 alpha-subunit (HIF-1alpha). Characterization of hif-1alpha-dependent and -independent hypoxia-inducible gene expression. J. Biol. Chem. 273, 8360-8368.
    • (1998) J. Biol. Chem. , vol.273 , pp. 8360-8368
    • Wood, S.M.1    Wiesener, M.S.2    Yeates, K.M.3    Okada, N.4    Pugh, C.W.5    Maxwell, P.H.6    Ratcliffe, P.J.7
  • 97
    • 0034649507 scopus 로고    scopus 로고
    • Identification of novel hypoxia dependent and independent target genes of the von Hippel-Lindau (VHL) tumor suppressor by mRNA differential expression profiling
    • Wykoff, C. C., Pugh, C. W., Maxwell, P. H., Harris, A. L. and Ratcliffe, P. J. (2000) Identification of novel hypoxia dependent and independent target genes of the von Hippel-Lindau (VHL) tumor suppressor by mRNA differential expression profiling. Oncogene 19, 6297-6305.
    • (2000) Oncogene , vol.19 , pp. 6297-6305
    • Wykoff, C.C.1    Pugh, C.W.2    Maxwell, P.H.3    Harris, A.L.4    Ratcliffe, P.J.5
  • 98
    • 0034849755 scopus 로고    scopus 로고
    • Interleukin-8 and human cancer biology
    • Xie, K. (2001) Interleukin-8 and human cancer biology. Cytokine Growth Factor Rev. 12, 375-391.
    • (2001) Cytokine Growth Factor Rev. , vol.12 , pp. 375-391
    • Xie, K.1
  • 99
    • 0034654174 scopus 로고    scopus 로고
    • Modulation of hypoxia-inducible factor lalpha expression by the epidermal growth factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP pathway in human prostate cancer cells: Implications for tumor angiogenesis and therapeutics
    • Zhong, H., Chiles, K., Feldser, D., Laughner, E., Hanrahan, C., Georgescu, M. M., Simons, J. W. and Semenza, G. L. (2000) Modulation of hypoxia-inducible factor lalpha expression by the epidermal growth factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP pathway in human prostate cancer cells: implications for tumor angiogenesis and therapeutics. Cancer Res. 60, 1541-1545.
    • (2000) Cancer Res. , vol.60 , pp. 1541-1545
    • Zhong, H.1    Chiles, K.2    Feldser, D.3    Laughner, E.4    Hanrahan, C.5    Georgescu, M.M.6    Simons, J.W.7    Semenza, G.L.8


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