Acetylation: A regulatory modification to rival phosphorylation

EMBO Journal

Volumn 19, Issue 6, 2000, Pages 1176-1179

  Kouzarides, Tony ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Acetylase; Acetylation; Deacetylase; Histones; Phosphorylation

Indexed keywords

ACYLTRANSFERASE; ALPHA TUBULIN; ENZYME; HISTONE; PHOSPHOTRANSFERASE; TRANSCRIPTION FACTOR;

ACETYLATION; ENZYME SPECIFICITY; MOLECULAR RECOGNITION; PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN MODIFICATION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; SHORT SURVEY; SIGNAL TRANSDUCTION;

GOES;

EID: 0034654011     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/19.6.1176     Document Type: Short Survey

References (38)

1. Ait-Si-Ali, A. et al. (1998) Histone acetyltransferase activity of CBP is controlled by cycle-dependent kinases and oncoprotein E1A. Nature, 396, 184-186.
2. Allfrey, V.G., Faulkner, R. and Mirsky, A.E. (1964) Acetylation and methylation of histones and their possible role in the regulation of RNA synthesis. Proc. Natl Acad. Sci. USA, 61, 786-794.
3. Bannister, A.J. and Kouzarides, T. (1996) The CBP co-activator is a histone acetyltransferase. Nature, 384, 641-643.
4. Bannister, A.J., Miska, E., Gorlich, D. and Kouzarides, T. (2000) Nuclear import factors acetylated by CBP/p300. Curr. Biol., in press.
5. Barlev, N.A., Poltoratsky, V., Owen-Hughes, T., Ying, C., Liu, L., Workman, J.L. and Berger, S.L. (1998) Repression of GCN5 histone acetyltransferase activity via bromodomain-mediated binding and phosphorylation by the Ku-DNA-dependent protein kinase complex. Mol. Cell. Biol., 18, 1349-1358.
6. Boyes, J., Byfield, P., Nakatani, Y. and Ogryzko, V. (1998) Regulation of activity of the transcription factor GATA-1 by acetylation. Nature, 396, 594-598.
7. Brownell, J.E., Zhou, J., Ranalli, T., Kobayashi, R., Edmondson, D.G., Roth, S.Y. and Allis, C.D. (1996) Tetrahymena histone acetyltransferase A: a homolog to yeast Gcn5p linking histone acetylation to gene activation. Cell, 84, 843-851.
8. Chakravarti, D., Ogryzko, V., Kao, H.Y. Nash, A., Chen, H., Nakatani, Y. and Evans, R.M. (1999) A viral mechanism for inhibition of p300 and PCAF acetyltransferase activity. Cell, 96, 393-403.
9. Chen, H., Lin, J.R., Xie, W., Wilpitz, D. and Evans, M.R. (1999) Regulation of hormone-induced histone hyperacetylation and gene activation via acetylation of an acetylase. Cell, 98, 675-686.
10. Dhalluin, C., Carlson, J.E., Zeng, L., He, C., Aggarwal, A. and Zhou, M. (1999) Structure and ligand of a histone acetyltransferase bromodomain. Nature, 399, 491-496.
11. Fischle, W., Emiliani, S., Hendzel, M.J., Nagase, T., Nomura, N., Voelter, W. and Verdin, E. (1999) A new family of human histone deacetylases related to Saccharomyces cerevisiae HDA1p. J. Biol. Chem., 274, 11713-11720.
12. Fuks, F., Milner, J. and Kouzarides, T. (1998) BRCA2 associates with acetyltransferase activity when bound to P/CAF. Oncogene, 17, 2531-2534.
13. Grozinger, C.M., Hassig, C.A. and Schreiber, S.L. (1999) Three proteins define a class of human histone deacetylases related to yeast Hdalp. Proc. Natl Acad. Sci. USA, 96, 4868-4873.
14. Grunstein, M. (1997) Histone acetylation in chromatin structure and transcription. Nature, 389, 349-352.
15. Gu, W. and Roeder, R.G. (1997) Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain. Cell, 90, 595-606.
16. Hamamori, Y., Sartorelli, V., Ogryzko, V., Puri, P.L., Wu, H.Y., Wang, J.Y.J., Nakatani, Y. and Kedes, L. (1999) Regulation of histone acetyltransferases p300 and PCAF by the bHLH protein twist and adenoviral oncoprotein E1A. Cell, 96, 405-413.
17. HerreraJ.E., Bergel, M., Yang, X.J., Nakatani, Y. and Bustin, M. (1997) The histone acetyltransferase activity of human GCN5 and PCAF is stabilized by coenzymes. J. Biol. Chem., 262, 27253-27258.
18. Imhof, A., Yang, X.J., Ogryzko, V.V., Nakatani, Y., Wolffe, A.P. and Ge, H. (1997) Acetylation of general transcription factors by histone acetyltransferases. Curr. Biol., 7, 689-692.
19. Kouzarides, T. (1999) Histone acetylases and deacetylases in cell proliferation. Curr. Opin. Genet. Dev., 9, 40-48.
20. L'Hernault, S.W. and Rosenbaum, J.L. (1985) Chlamydomonas α-tubulin is posttranslationally modified by acetylation on the ε-amino group of a lysine. Biochemistry, 24, 473-478.
21. Liu, L., Scolnick, D.M., Trievel, R.C., Zhang, H.B., Marmorstein, R., Halazonetis, T.D. and Berger, S.L. (1999) p53 sites acetylated in vitro by PCAF and p300 are acetylated in vivo in response to DNA damage. Mol. Cell. Biol., 19, 1202-1209.
22. Martínez-Balbás, M., Bauer, U.-M., Nielsen, S.J., Brehm, A. and Kouzarides, T. (2000) Regulation of E2F1 activity by acetylation. EMBO J., 19, 662-671.
23. Marzio, G., Wagener, C., Gutierrez, M.I., Cartwright, P., Helin, K. and Giacca, M. (2000) E2F family members are differentially regulated by reverse acetylation. J. Biol Chem., in press.
24. Miska, E., Karlsson, C., Langley, E., Nielsen, S., Pines, J. and Kouzarides, T. (1999) HDAC4 deacetylase associates with and represses the MEF2 transcription factor. EMBO J., 18, 5099-5107.
25. Munshi, N., Merika, M., Yie, J., Senger, K., Chen, G. and Thanos, D. (1998) Acetylation of HMG1 (Y) by CBP turns off IFNβ expression by disrupting the enhanceosome. Mol. Cell, 2, 457-467.
26. Reid, J.L., Bannister, A.J., Zegerman, P., Martínez-Balbás, M. and Kouzarides, T. (1998) E1A directly binds and regulates the P/CAF acetyltransferase. EMBO J., 17, 4469-4477.
27. Rojas, J.R., Trievel, R.C., Zhou, J., Mo, Y., Li, X., Berger, S.L., Allis, C.D. and Marmorstein, R. (1999) Structure of Tetrahymena GCN5 bound to coenzyme A and a histone H3 peptide. Nature, 401, 93-97.
28. Rundlett, S.E., Carmen, A.A., Suka, N., Turner, B.M. and Grunstein, M. (1998) Transcriptional repression by UME6 involves deacetylation of lysine 5 of histone H4 by RPD3. Nature, 392, 831-835.
29. Sakaguchi, K., Herrera, J.E., Saito, S., Miki, T., Bustin, M., Vassilev, A., Anderson, C.W. and Appella, E. (1998) DNA damage activates p53 through a phosphorylation-acetylation cascade. Genes Dev., 12, 2831-2841.
30. Siddique, H., Zou, J.P., Rao, V.N., Shyam, E. and Reddy, P. (1998) The BRCA2 is a histone acetyltransferase. Oncogene, 16, 2283-2285.
31. Sterner, R., Vidali, G. and Allfrey, V.G. (1979) Studies of acetylation and deacetylation in high mobility group proteins. Identification of the sites of acetylation in HMG-1. J. Biol. Chem., 254, 11577-11583.
32. Takemura, R., Okabe, S., Umeyama, T., Kanai, Y., Cowan, N.J. and Hirokawa, N. (1992) Increased microtubule stability and α tubulin acetylation in cells transfected with microtubule-associated proteins MAP1B, MAP2 or τ. J. Cell Sci., 103, 953-964.
33. Taunton, J., Hassig, C.A. and Schreiber, S.L. (1996) A mammalian histone deacetylase related to the yeast transcriptional regulator Rpd3p. Science, 272, 408-411.
34. Verdel, A. and Khochbin, S. (1999) Identification of a new family of higher eukaryotic histone deacetylases. J. Biol. Chem., 274, 2440-2445.
35. Waltzer, L. and Bienz, M. (1998) Drosophila CBP represses the transcription factor TCF to antagonize Wingless signalling. Nature, 395, 521-525.
36. Wang, A.H., Bertos, N.R., Vezmar, M., Pelletier, N., Crosato, M., Heng, H.H., Th'ng, J., Han, J. and Yang, X.-J. (1999) HDAC4, a human histone deacetylase related to yeast HDA1, is a transcriptional corepressor. Mol. Cell. Biol., 19, 7816-7827.
37. Yamamoto, T. and Horikoshi, M. (1997) Novel substrate specificity of the histone acetyltransferase activity of HIV-1-Tat interactive protein Tip60. J. Biol. Chem., 272, 30595-30598.
38. Zhang, W. and Bieker, J.J. (1998) Acetylation and modulation of erythroid Kruppel-like factor (EKLF) activity by interaction with histone acetyltransferases. Proc. Natl Acad. Sci. USA, 95, 9855-9860.