FIH-1: A novel protein that interacts with HIF-1α and VHL to mediate repression of HIF-1 transcriptional activity

Genes and Development

Volumn 15, Issue 20, 2001, Pages 2675-2686

  Mahon, P C ^a   Hirota, K ^a   Semenza, G L ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Corepressor; Histone deacetylase; Hypoxia; Transactivation

Indexed keywords

HISTONE DEACETYLASE; HYPOXIA INDUCIBLE FACTOR 1; PROTEIN FIH1; UNCLASSIFIED DRUG;

ANGIOGENESIS; APOPTOSIS; ARTICLE; ERYTHROPOIESIS; GENE ACTIVATION; GENE REPRESSION; GENE TARGETING; GLYCOLYSIS; HUMAN; HUMAN CELL; HYDROXYLATION; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; TRANSACTIVATION; TRANSCRIPTION REGULATION; VON HIPPEL LINDAU DISEASE;

AMINO ACID SEQUENCE; ANIMALS; CELL HYPOXIA; CELLS, CULTURED; DNA PRIMERS; FUNGAL PROTEINS; GENE EXPRESSION REGULATION; GLUTATHIONE TRANSFERASE; HISTONE DEACETYLASES; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; LIGASES; LUCIFERASES; MOLECULAR SEQUENCE DATA; NUCLEAR PROTEINS; OXYGEN; POLYMERASE CHAIN REACTION; PROTEIN CONFORMATION; RABBITS; REPRESSOR PROTEINS; RETICULOCYTES; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; SIGNAL TRANSDUCTION; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TUMOR SUPPRESSOR PROTEINS; TWO-HYBRID SYSTEM TECHNIQUES; UBIQUITIN-PROTEIN LIGASES; VON HIPPEL-LINDAU TUMOR SUPPRESSOR PROTEIN;

EID: 0035887011     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.924501     Document Type: Article

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