-
1
-
-
0033407456
-
Von hippel-lindau syndrome: A pleomorphic condition
-
Friedrich CA. Von Hippel-Lindau syndrome: a pleomorphic condition. Cancer 1999;86:1658-1662.
-
(1999)
Cancer
, vol.86
, pp. 1658-1662
-
-
Friedrich, C.A.1
-
2
-
-
0025076389
-
Von Hippel-Lindau disease: Clinical review and molecular genetics
-
Glenn GM, Choyke PL, Zbar B et al. Von Hippel-Lindau disease: clinical review and molecular genetics. Problems in Urology 1990;4:312-330.
-
(1990)
Problems in Urology
, vol.4
, pp. 312-330
-
-
Glenn, G.M.1
Choyke, P.L.2
Zbar, B.3
-
3
-
-
0345164318
-
The VHL tumour-suppressor gene paradigm
-
Kaelin WG Jr, Maher ER. The VHL tumour-suppressor gene paradigm. Trends Genet 1998;14:423-426.
-
(1998)
Trends Genet
, vol.14
, pp. 423-426
-
-
Kaelin W.G., Jr.1
Maher, E.R.2
-
4
-
-
0033051828
-
The von Hippel-Lindau tumour suppressor protein: New perspectives
-
Ohh M, Kaelin WG Jr. The von Hippel-Lindau tumour suppressor protein: new perspectives. Mol Med Today 1999;5:257-263.
-
(1999)
Mol Med Today
, vol.5
, pp. 257-263
-
-
Ohh, M.1
Kaelin W.G., Jr.2
-
5
-
-
0025000210
-
Clinical features and natural history of von Hippel-Lindau disease
-
Maher ER, Yates JR, Harries R et al. Clinical features and natural history of von Hippel-Lindau disease. QJM 1990;77:1151-1163.
-
(1990)
QJM
, vol.77
, pp. 1151-1163
-
-
Maher, E.R.1
Yates, J.R.2
Harries, R.3
-
6
-
-
0027240519
-
Identification of the von Hippel-Lindau disease tumor suppressor gene
-
Latif F, Tory K, Gnarra J et al. Identification of the von Hippel-Lindau disease tumor suppressor gene. Science 1993;260:1317-1320.
-
(1993)
Science
, vol.260
, pp. 1317-1320
-
-
Latif, F.1
Tory, K.2
Gnarra, J.3
-
7
-
-
0028981766
-
Germline mutations in the von Hippel-Lindau disease tumor suppressor gene: Correlations with phenotype
-
Chen F, Kishida T, Yao M et al. Germline mutations in the von Hippel-Lindau disease tumor suppressor gene: correlations with phenotype. Hum Mutat 1995;5:66-75.
-
(1995)
Hum Mutat
, vol.5
, pp. 66-75
-
-
Chen, F.1
Kishida, T.2
Yao, M.3
-
8
-
-
0032970571
-
Mutations of the VHL gene in sporadic renal cell carcinoma: Definition of a risk factor for VHL patients to develop an RCC
-
Gallou C, Joly D, Mejean A et al. Mutations of the VHL gene in sporadic renal cell carcinoma: definition of a risk factor for VHL patients to develop an RCC. Hum Mutat 1999;13:464-475.
-
(1999)
Hum Mutat
, vol.13
, pp. 464-475
-
-
Gallou, C.1
Joly, D.2
Mejean, A.3
-
9
-
-
0031834186
-
Genotype-phenotype correlations in von Hippel-Lindau disease
-
Neumann HP, Bender BU. Genotype-phenotype correlations in von Hippel-Lindau disease. J Intern Med 1998;243:541-545.
-
(1998)
J Intern Med
, vol.243
, pp. 541-545
-
-
Neumann, H.P.1
Bender, B.U.2
-
10
-
-
0032729680
-
Two distinct phenotypes caused by two different missense mutations in the same codon of the VHL gene
-
Bradley JF, Collins DL, Schimke RN et al. Two distinct phenotypes caused by two different missense mutations in the same codon of the VHL gene. Am J Med Genet 1999;87:163-167.
-
(1999)
Am J Med Genet
, vol.87
, pp. 163-167
-
-
Bradley, J.F.1
Collins, D.L.2
Schimke, R.N.3
-
11
-
-
2642668463
-
Germline mutations in the vhl gene in patients presenting with phaeochromocytomas
-
van der Harst E, de Krijger RR, Dinjens WN et al. Germline mutations in the vhl gene in patients presenting with phaeochromocytomas. Int J Cancer 1998;77:337-340.
-
(1998)
Int J Cancer
, vol.77
, pp. 337-340
-
-
Van Der Harst, E.1
De Krijger, R.R.2
Dinjens, W.N.3
-
12
-
-
0032231366
-
An analysis of phenotypic variation in the familial cancer syndrome von Hippel-Lindau disease: Evidence for modifier effects
-
Webster AR, Richards FM, MacRonald FE et al. An analysis of phenotypic variation in the familial cancer syndrome von Hippel-Lindau disease: evidence for modifier effects. Am J Hum Genet 1998;63:1025-1035.
-
(1998)
Am J Hum Genet
, vol.63
, pp. 1025-1035
-
-
Webster, A.R.1
Richards, F.M.2
MacRonald, F.E.3
-
13
-
-
0033037128
-
Clinical characteristics of ocular angiomatosis in von Hippel-Lindau disease and correlation with germline mutation
-
Webster AR, Maher ER, Moore AT. Clinical characteristics of ocular angiomatosis in von Hippel-Lindau disease and correlation with germline mutation. Arch Ophthalmol 1999;117:371-378.
-
(1999)
Arch Ophthalmol
, vol.117
, pp. 371-378
-
-
Webster, A.R.1
Maher, E.R.2
Moore, A.T.3
-
14
-
-
0028938702
-
Von Hippel-Lindau disease: Genetic, clinical, and imaging features
-
published erratum appears in Radiology 1995;196:582
-
Choyke PL, Glenn GM, Walther MM et al. von Hippel-Lindau disease: genetic, clinical, and imaging features [published erratum appears in Radiology 1995;196:582]. Radiology 1995;194:629-642.
-
(1995)
Radiology
, vol.194
, pp. 629-642
-
-
Choyke, P.L.1
Glenn, G.M.2
Walther, M.M.3
-
15
-
-
0032616617
-
Von Hippel-Lindau disease: Strategies in early detection (renal-, adrenal-, pancreatic masses)
-
Hes FJ, Feldberg MA. Von Hippel-Lindau disease: strategies in early detection (renal-, adrenal-, pancreatic masses). Eur Radiol 1999;9:598-610.
-
(1999)
Eur Radiol
, vol.9
, pp. 598-610
-
-
Hes, F.J.1
Feldberg, M.A.2
-
16
-
-
0345086463
-
One ring to rule a superfamily of E3 ubiquitin ligases
-
Tyers M, Willems AR. One ring to rule a superfamily of E3 ubiquitin ligases. Science 1999;284:601-604.
-
(1999)
Science
, vol.284
, pp. 601-604
-
-
Tyers, M.1
Willems, A.R.2
-
17
-
-
0031831274
-
Combinatorial control in ubiquitin-dependent proteolysis: Don't Skp the F-box hypothesis
-
Patton EE, Willems AR, Tyers M. Combinatorial control in ubiquitin-dependent proteolysis: don't Skp the F-box hypothesis. Trends Genet 1998;14:236-243.
-
(1998)
Trends Genet
, vol.14
, pp. 236-243
-
-
Patton, E.E.1
Willems, A.R.2
Tyers, M.3
-
18
-
-
0033574737
-
Structure of the VHL-ElonginC-ElonginB complex: Implications for VHL tumor suppressor function
-
Stebbins CE, Kaelin WG Jr, Pavletich NP. Structure of the VHL-ElonginC-ElonginB complex: implications for VHL tumor suppressor function. Science 1999;284:455-461.
-
(1999)
Science
, vol.284
, pp. 455-461
-
-
Stebbins, C.E.1
Kaelin W.G., Jr.2
Pavletich, N.P.3
-
19
-
-
0033578405
-
Studying interactions of four proteins in the yeast two-hybrid system: Structural resemblance of the pVHL/elongin BC/hCUL-2 complex with the ubiquitin ligase complex SKP1/cullin/F-box protein
-
Pause A, Peterson B, Schaffar G et al. Studying interactions of four proteins in the yeast two-hybrid system: structural resemblance of the pVHL/elongin BC/hCUL-2 complex with the ubiquitin ligase complex SKP1/cullin/F-box protein. Proc Natl Acad Sci USA 1999;96:9533-9538.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 9533-9538
-
-
Pause, A.1
Peterson, B.2
Schaffar, G.3
-
20
-
-
0033545860
-
Conjugation of the ubiquitin-like protein NEDD8 to cullin-2 is linked to von Hippel-Lindau tumor suppressor function
-
Liakopoulos D, Busgen T, Brychzy A et al. Conjugation of the ubiquitin-like protein NEDD8 to cullin-2 is linked to von Hippel-Lindau tumor suppressor function. Proc Natl Acad Sci USA 1999;96:5510-5515.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 5510-5515
-
-
Liakopoulos, D.1
Busgen, T.2
Brychzy, A.3
-
21
-
-
0033565672
-
The von Hippel-Lindau tumor suppressor protein is a component of an E3 ubiquitin-protein ligase activity
-
Lisztwan J, Imbert G, Wirbelauer C et al. The von Hippel-Lindau tumor suppressor protein is a component of an E3 ubiquitin-protein ligase activity. Genes Dev 1999;13:1822-1833.
-
(1999)
Genes Dev
, vol.13
, pp. 1822-1833
-
-
Lisztwan, J.1
Imbert, G.2
Wirbelauer, C.3
-
22
-
-
0033529771
-
Binding of elongin A or a von Hippel-Lindau peptide stabilizes the structure of yeast elongin C
-
Botuyan MV, Koth CM, Mer G et al. Binding of elongin A or a von Hippel-Lindau peptide stabilizes the structure of yeast elongin C. Proc Natl Acad Sci USA 1999;96:9033-9038.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 9033-9038
-
-
Botuyan, M.V.1
Koth, C.M.2
Mer, G.3
-
23
-
-
0031869573
-
Subcellular localization of the von Hippel-Lindau disease gene product is cell cycle-dependent
-
Ye Y, Vasavada S, Kuzmin I et al. Subcellular localization of the von Hippel-Lindau disease gene product is cell cycle-dependent. Int J Cancer 1998;78:62-69.
-
(1998)
Int J Cancer
, vol.78
, pp. 62-69
-
-
Ye, Y.1
Vasavada, S.2
Kuzmin, I.3
-
24
-
-
0344026345
-
Transcription-dependent nuclear-cytoplasmic trafficking is required for the function of the von Hippel-Lindau tumor suppressor protein
-
Lee S, Neumann M, Stearman R et al. Transcription-dependent nuclear-cytoplasmic trafficking is required for the function of the von Hippel-Lindau tumor suppressor protein. Mol Cell Biol 1999;19:1486-1497.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 1486-1497
-
-
Lee, S.1
Neumann, M.2
Stearman, R.3
-
25
-
-
0032928890
-
Expression of the von Hippel-Lindau-binding protein-1 (Vbp1) in fetal and adult mouse tissues
-
Hemberger M, Himmelbauer H, Neumann HP et al. Expression of the von Hippel-Lindau-binding protein-1 (Vbp1) in fetal and adult mouse tissues. Hum Mol Genet 1999;8:229-236.
-
(1999)
Hum Mol Genet
, vol.8
, pp. 229-236
-
-
Hemberger, M.1
Himmelbauer, H.2
Neumann, H.P.3
-
26
-
-
0033597443
-
Rbx1, a component of the VHL tumor suppressor complex and SCF ubiquitin ligase
-
Kamura T, Koepp DM, Conrad MN et al. Rbx1, a component of the VHL tumor suppressor complex and SCF ubiquitin ligase. Science 1999;284:657-661.
-
(1999)
Science
, vol.284
, pp. 657-661
-
-
Kamura, T.1
Koepp, D.M.2
Conrad, M.N.3
-
27
-
-
0033600881
-
Direct interaction of the beta-domain of VHL tumor suppressor protein with the regulatory domain of atypical PKC isotypes
-
Okuda H, Hirai S, Takaki Y et al. Direct interaction of the beta-domain of VHL tumor suppressor protein with the regulatory domain of atypical PKC isotypes. Biochem Biophys Res Commun 1999;263:491-497.
-
(1999)
Biochem Biophys Res Commun
, vol.263
, pp. 491-497
-
-
Okuda, H.1
Hirai, S.2
Takaki, Y.3
-
28
-
-
0032555217
-
A second major native von Hippel-Lindau gene product, initiated from an internal translation start site, functions as a tumor suppressor
-
Schoenfeld A, Davidowitz EJ, Burk RD. A second major native von Hippel-Lindau gene product, initiated from an internal translation start site, functions as a tumor suppressor. Proc Natl Acad Sci USA 1998;95:8817-8822.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 8817-8822
-
-
Schoenfeld, A.1
Davidowitz, E.J.2
Burk, R.D.3
-
29
-
-
0032578357
-
PVHL19 is a biologically active product of the von Hippel-Lindau gene arising from internal translation initiation
-
Iliopoulos O, Ohh M, Kaelin WG Jr. pVHL19 is a biologically active product of the von Hippel-Lindau gene arising from internal translation initiation. Proc Natl Acad Sci USA 1998;95:11661-11666.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 11661-11666
-
-
Iliopoulos, O.1
Ohh, M.2
Kaelin W.G., Jr.3
-
30
-
-
0033602089
-
Alternate choice of initiation codon produces a biologically active product of the von Hippel Lindau gene with tumor suppressor activity
-
Blankenship C, Naglich JG, Whaley JM et al. Alternate choice of initiation codon produces a biologically active product of the von Hippel Lindau gene with tumor suppressor activity. Oncogene 1999;18:1529-1535.
-
(1999)
Oncogene
, vol.18
, pp. 1529-1535
-
-
Blankenship, C.1
Naglich, J.G.2
Whaley, J.M.3
-
31
-
-
0032535364
-
The Elongin BC complex interacts with the conserved SOCS-box motif present in members of the SOCS, ras. Wd-40 repeat, and ankyrin repeat families
-
Kamura T, Sato S, Haque D et al. The Elongin BC complex interacts with the conserved SOCS-box motif present in members of the SOCS, ras. WD-40 repeat, and ankyrin repeat families. Genes Dev 1998;12:3872-3881.
-
(1998)
Genes Dev
, vol.12
, pp. 3872-3881
-
-
Kamura, T.1
Sato, S.2
Haque, D.3
-
32
-
-
0033587146
-
The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis
-
Maxwell PH, Wiesener MS, Chang GW et al. The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis [letter]. Nature 1999;399:271-275.
-
(1999)
Nature
, vol.399
, pp. 271-275
-
-
Maxwell, P.H.1
Wiesener, M.S.2
Chang, G.W.3
-
33
-
-
0029785321
-
Negative regulation of hypoxia-inducible genes by the von Hippel-Lindau protein
-
Iliopoulos O, Levy AP, Jiang C et al. Negative regulation of hypoxia-inducible genes by the von Hippel-Lindau protein. Proc Natl Acad Sci USA 1996;93:10595-10599.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 10595-10599
-
-
Iliopoulos, O.1
Levy, A.P.2
Jiang, C.3
-
34
-
-
0031823016
-
The molecular basis of the hypoxia response pathway: Tumour hypoxia as a therapy target
-
Blancher C, Harris AL. The molecular basis of the hypoxia response pathway: tumour hypoxia as a therapy target. Cancer Metastasis Rev 1998;17:187-194.
-
(1998)
Cancer Metastasis Rev
, vol.17
, pp. 187-194
-
-
Blancher, C.1
Harris, A.L.2
-
35
-
-
0030816109
-
Hypoxia-inducible factor-1 modulates gene expression in solid tumors and influences both angiogenesis and tumor growth
-
Maxwell PH, Dachs GU, Gleadle JM et al. Hypoxia-inducible factor-1 modulates gene expression in solid tumors and influences both angiogenesis and tumor growth. Proc Natl Acad Sci USA 1997;94:8104-8109.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 8104-8109
-
-
Maxwell, P.H.1
Dachs, G.U.2
Gleadle, J.M.3
-
36
-
-
0032189844
-
Induction of endothelial PAS domain protein-1 by hypoxia: Characterization and comparison with hypoxia-inducible factor-1 alpha
-
Wiesener MS, Turley H, Allen WE et al. Induction of endothelial PAS domain protein-1 by hypoxia: characterization and comparison with hypoxia-inducible factor-1 alpha. Blood 1998;92:2260-2268.
-
(1998)
Blood
, vol.92
, pp. 2260-2268
-
-
Wiesener, M.S.1
Turley, H.2
Allen, W.E.3
-
37
-
-
0033135109
-
Transforming growth factor betal is a target for the von Hippel-Lindau tumor suppressor and a critical growth factor for clear cell renal carcinoma
-
Ananth S, Knebelmann B, Grüning W et al. Transforming growth factor betal is a target for the von Hippel-Lindau tumor suppressor and a critical growth factor for clear cell renal carcinoma. Cancer Res 1999;59:2210-2216.
-
(1999)
Cancer Res
, vol.59
, pp. 2210-2216
-
-
Ananth, S.1
Knebelmann, B.2
Grüning, W.3
-
38
-
-
0032795938
-
The von Hippel-Lindau tumor suppressor gene inhibits hepatocyte growth factor/scatter factor-induced invasion and branching morphogenesis in renal carcinoma cells
-
Koochekpour S. Jeffers M, Wang PH et al. The von Hippel-Lindau tumor suppressor gene inhibits hepatocyte growth factor/scatter factor-induced invasion and branching morphogenesis in renal carcinoma cells. Mol Cell Biol 1999;19:5902-5912.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 5902-5912
-
-
Koochekpour, S.1
Jeffers, M.2
Wang, P.H.3
-
39
-
-
0033199018
-
Regulation of the urokinase-type plasminogen activator system by the von Hippel-Lindau tumor suppressor gene
-
Los M, Zeamari S, Foekens JA et al. Regulation of the urokinase-type plasminogen activator system by the von Hippel-Lindau tumor suppressor gene. Cancer Res 1999;59:4440-4445.
-
(1999)
Cancer Res
, vol.59
, pp. 4440-4445
-
-
Los, M.1
Zeamari, S.2
Foekens, J.A.3
-
40
-
-
0032514685
-
Down-regulation of transmembrane carbonic anhydrases in renal cell carcinoma cell lines by wild-type von Hippel-Lindau transgenes
-
Ivanov SV, Kuzmin I, Wei MH et al. Down-regulation of transmembrane carbonic anhydrases in renal cell carcinoma cell lines by wild-type von Hippel-Lindau transgenes. Proc Natl Acad Sci USA 1998;95:12596-12601.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 12596-12601
-
-
Ivanov, S.V.1
Kuzmin, I.2
Wei, M.H.3
-
41
-
-
0032085240
-
The von Hippel-Lindau tumor suppressor protein is required for proper assembly of an extracellular fibronectin matrix
-
Ohh M, Yauch RL, Lonergan KM et al. The von Hippel-Lindau tumor suppressor protein is required for proper assembly of an extracellular fibronectin matrix. Mol Cell 1998;1:959-968.
-
(1998)
Mol Cell
, vol.1
, pp. 959-968
-
-
Ohh, M.1
Yauch, R.L.2
Lonergan, K.M.3
-
42
-
-
0032211161
-
Coexpression of erythropoietin and vascular endothelial growth factor in nervous system tumors associated with von Hippel-Lindau tumor suppressor gene loss of function
-
Krieg M, Marti HH, Plate KH. Coexpression of erythropoietin and vascular endothelial growth factor in nervous system tumors associated with von Hippel-Lindau tumor suppressor gene loss of function. Blood 1998;92:3388-3393.
-
(1998)
Blood
, vol.92
, pp. 3388-3393
-
-
Krieg, M.1
Marti, H.H.2
Plate, K.H.3
-
43
-
-
0032773625
-
Inverse regulation of vascular endothelial growth factor and VHL tumor suppressor gene in sporadic renal cell carcinomas is correlated with vascular growth: An in vivo study on 29 tumors
-
Brieger J, Weidl EJ, Schirmacher P et al. Inverse regulation of vascular endothelial growth factor and VHL tumor suppressor gene in sporadic renal cell carcinomas is correlated with vascular growth: an in vivo study on 29 tumors. J Mol Med 1999;77:505-510.
-
(1999)
J Mol Med
, vol.77
, pp. 505-510
-
-
Brieger, J.1
Weidl, E.J.2
Schirmacher, P.3
-
44
-
-
0031870653
-
Up-regulation of vascular endothelial growth factor in stromal cells of hemangioblastomas is correlated with up-regulation of the transcription factor HRF/HIF-2alpha
-
Flamme I, Krieg M, Plate KH. Up-regulation of vascular endothelial growth factor in stromal cells of hemangioblastomas is correlated with up-regulation of the transcription factor HRF/HIF-2alpha. Am J Pathol 1998;153:25-29.
-
(1998)
Am J Pathol
, vol.153
, pp. 25-29
-
-
Flamme, I.1
Krieg, M.2
Plate, K.H.3
-
45
-
-
0028929991
-
Up-regulation of vascular endothelial growth factor and its receptors in von Hippel-Lindau disease-associated and sporadic hemangioblastomas
-
Wizigmann-Voos S, Breier G, Risau W et al. Up-regulation of vascular endothelial growth factor and its receptors in von Hippel-Lindau disease-associated and sporadic hemangioblastomas. Cancer Res 1995;55:1358-1364.
-
(1995)
Cancer Res
, vol.55
, pp. 1358-1364
-
-
Wizigmann-Voos, S.1
Breier, G.2
Risau, W.3
|