Hypoxia induces transcription factor ETS-1 via the activity of hypoxia-lnducible factor-1

Biochemical and Biophysical Research Communications

Volumn 289, Issue 1, 2001, Pages 39-43

  Oikawa, Manami ^a,b   Abe, Mayumi ^a   Kurosawa, Hajime ^b   Hida, Wataru ^b   Shirato, Kunio ^b   Sato, Yasufumi ^a  

^a TOHOKU UNIVERSITY   (Japan)

^b TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Angiogenesis; ETS 1; HIF 1; Hypoxia; Tumor invasion

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1; TRANSCRIPTION FACTOR;

ANGIOGENESIS; ARTICLE; BLADDER CANCER; CANCER INVASION; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; HYPOXIA; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION;

EID: 0035941117     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.2001.5927     Document Type: Article

References (21)

1. The ETS-domain transcription factor family
2. Ets-1 regulates angiogenesis by inducing the expression of urokinase-type plasminogen activator and matrix metalloproteinase-1 and the migration of vascular endothelial cells
3. Induction of Ets-1 in endothelial cells during re-endothelialization after denuding injury
4. Roles of ERK1/2 and p38 MAP kinase in the signal transduction of bFGF in endothelial cells during angiogenesis
5. Properties of two VEGF receptors, Flt-1 and KDR, in the signal transduction
6. ETS-1 converts endothelial cells to the angiogenic phenotype by inducing the expression of matrix metalloproteinases and integrin β3
7. Angiogenesis inhibition by transdominant mutant Ets-1
8. Expression of the Ets-1 proto-oncogene in human gastric carcinoma: Correlation with tumor invasion
9. Expression of c-ets-1, collagenase 1, and urokinase-type plasminogen activator genes in lung carcinomas
10. The expression of an Ets-1 transcription factor lacking its activation domain decreases uPA proteolytic activity and cell motility, and impairs normal tubulogenesis and cancerous scattering in mammary epithelial cells
11. Ets-1 transcription factor-mediated urokinase-type plasminogen activator expression and invasion in glioma cells stimulated by serum and basic fibroblast growth factors
12. HIF-1 and mechanisms of hypoxia sensing
13. Rapid detection of octamer binding proteins with "mini-extracts" prepared from a small number of cells
14. The human ETS-1 gene: Genomic structure, promoter characterization, and alternative splicing
15. Role of AP-1 complex in angiotensin II-mediated transforming growth factor-beta expression and growth of smooth muscle cells: Using decoy approach against AP-1 binding site
16. Tumor hypoxia: Definitions and current clinical, biologic, and molecular aspects
17. V-SRC induces expression of hypoxia-inducible factor 1 (HIF-1) and transcription of genes encoding vascular endothelial growth factor and enolase 1: Involvement of HIF-1 in tumor progression
18. Targeting gene expression to hypoxic tumor cells
19. Levels of hypoxia-inducible factor-1α during breast carcinogenesis
20. HIF-1α is required for solid tumor formation and embryonic vascularization
21. Role of HIF-1α in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis