Degradation of the cyclin-dependent-kinase inhibitor p27(Kip1) is instigated by Jab1

Nature

Volumn 398, Issue 6723, 1999, Pages 160-165

  Tomoda, Kiichiro ^a   Kubota, Yukiko ^a   Kato, Jun Ya ^a  

^a NARA INSTITUTE OF SCIENCE AND TECHNOLOGY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR; PROTEIN P27;

AMINO ACID SEQUENCE; ARTICLE; CELL CYCLE; CELL CYCLE G1 PHASE; MITOSIS INHIBITION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN TRANSPORT; SEQUENCE ANALYSIS;

3T3 CELLS; ANIMALS; CELL CYCLE; CELL CYCLE PROTEINS; COS CELLS; CYCLIN-DEPENDENT KINASE INHIBITOR P27; CYCLIN-DEPENDENT KINASES; DNA-BINDING PROTEINS; DOWN-REGULATION; ENZYME INHIBITORS; G1 PHASE; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MICE, INBRED BALB C; MICROTUBULE-ASSOCIATED PROTEINS; MUTAGENESIS; PEPTIDE HYDROLASES; PROTEIN BINDING; RECOMBINANT FUSION PROTEINS; TRANSCRIPTION FACTORS; TUMOR SUPPRESSOR PROTEINS;

MAMMALIA;

EID: 0033545636     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/18230     Document Type: Article

References (30)

1. Sherr, C. J. Cancer cell cycles. Science 274, 1672-1677 (1996).
2. Steeg, P. S. & Abrams, J. S. Cancer prognostics: Past, present and p27. Nature Med. 3, 152-154 (1997).
3. Kip1 accumulation during the cell cycle. Science 271, 1861-1864 (1996).
4. Kip1. Genes Dev. 11, 1464-1478 (1997).
5. Kip1. EMBO J. 16, 5334-5344 (1997).
6. Pagano, M. et al. Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27. Science 269, 682-685 (1995).
7. Kip1 is abrogated by c-Myc. EMBO J. 15, 6595-6604 (1996).
8. Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-β and contact inhibition to cell cycle arrest. Genes Dev. 8, 9-22 (1994).
9. Kip1 by the viral EIA oncoprotein in TGFβ-treated cells. Nature 380, 262-265 (1996).
10. Claret, F. X. et al. A new group of conserved coactivators that increase the specificity of AP-1 transcription factors. Nature 383, 453-457 (1996).
11. Durfee, T. et al. The retinoblastoma protein associates with the protein phosphatase type 1 catalytic subunit. Genes Dev. 7, 555-569 (1993).
12. Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals. Cells 78, 59-66 (1994).
13. Hofmann, K. & Bucher, P. The PCI domain: a common theme in three multiprotein complexes. Trends Biochem. Sci. 23, 204-205 (1998).
14. Asano, K. et al. Structure of cDNAs encoding human eukaryotic initiation factor 3 subunits. Possible roles in RNA binding and macromolecular assembly. J. Biol. Chem. 272, 27042-27052 (1997).
15. Cip1 Cdk inhibitor family, is a candidate tumor suppressor gene. Genes Dev. 9, 650-662 (1995).
16. Ogawa, H., Inouye, S., Tsuji, F. I., Yasuda, K. & Umesono, K. Localization, trafficking, and temperature-dependence of the Acquorea green fluorescent-protein in cultured vertebrate cells. Proc. Natl Acad. Sci. USA 92, 11899-11903 (1995).
17. Rock, K. L. et al. Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules. Cell 78, 761-771 (1994).
18. Nishi, K. et al. Leptomycin B targets a regulatory cascade of crm1, a fission yeast nuclear protein, involved in control of higher order chromosome structure and gene expression. J. Biol. Chem. 269, 6320-6324 (1994).
19. Fukuda, M. et al. CRM1 is responsible for intracellular transport mediated by the nuclear export signal. Nature 390, 308-311 (1997).
20. Fukuda, M., Gotoh, I., Adachi, M., Gotoh, Y. & Nishida, E. A novel regulatory mechanism in the mitogen-activated protein (MAP) kinase cascade. Role of nuclear export signal of MAP kinase kinase. J. Biol. Chem. 272, 32642-32648 (1997).
21. Kip1 for restriction point control of the fibroblast cell cycle. Science 272, 877-880 (1996).
22. Seeger, M. et al. A novel protein complex involved in signal transduction possessing similarities to 26S proteasome subunits. FASEB J. 12, 469-478 (1998).
23. Wei, N. et al. The COP9 complex is conserved between plants and mammals and is related to the 26S proteasome regulatory complex. Curr. Biol. 8, 919-922 (1998).
24. Glickman, M. H. et al. A subcomplex of the proteasome regulatory particle required for ubiquitin-conjugate degradation and related to the COP9-signalosome and eIF3. Cell 94, 615-623 (1998).
25. Harper, J. W., Adami, G., Wei, N., Keyomarsi, K. & Elledge, S. J. The 21 kd Cdk interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases. Cell 75, 805-816 (1993).
26. Hirai, H., Roussel, M. F., Kato, J.-y., Ashmun, R. A. & Sherr, C. J. Novel INK4 proteins, p19 and p18, are specific inhibitors of the cyclin D-dependent kinases CDK4 and CDK6. Mol. Cell. Biol. 15, 2672-2681 (1995).
27. Akamatsu, E., Tanaka, T. & Kato, J.-y. Transcription factor E2E and cyclin E/cdk2 complex cooperate to induce chromosomal DNA replication in Xenopus oocytes. J. Biol. Chem. 273, 16494-16500 (1998).
28. Kato, J.-y., Matsushime, H., Hiebert, S. W., Ewen, M. E. & Sherr, C. J. Direct binding of cyclin D to the retinoblastoma gene product (pRb) and pRb phosphorylation by the cyclin D-dependent kinase, CDK4. Genes Dev. 7, 331-342 (1993).
29. Tanaka, M. & Herr, W. Differential transcriptional activation by Oct-1 and Oct-2: interdependent activation domains induce Oct-2 phosphorylation. Cell 60, 375-386 (1990).
30. Chen, C. & Okayama, H. High-efficiency transformation of mammalian cells by plasmid DNA. Mol. Cell. Biol. 7, 2745-2752 (1987).