VEGF and therapeutic opportunities in cardiovascular diseases

Current Opinion in Biotechnology

Volumn 10, Issue 6, 1999, Pages 541-543

  Schaper, Wolfgang ^a   Buschmann, Ivo ^a  

^a MAX PLANCK INSTITUTE FOR HEART AND LUNG RESEARCH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOGENESIS INHIBITOR; VASCULOTROPIN;

ANGIOGENESIS; ATHEROSCLEROSIS; CARDIOVASCULAR DISEASE; HYPOXIA; PRIORITY JOURNAL; REVASCULARIZATION; SHORT SURVEY; TUMOR VASCULARIZATION; VASCULAR ENDOTHELIUM;

EID: 0032712252     PISSN: 09581669     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0958-1669(99)00032-4     Document Type: Review

References (24)

1. Carmeliet P., Collen D. Molecular analysis of blood vessel formation and disease. Am J Physiol. 42:1997;H2091-H2104.
2. Rosengart T.K., Patel S.R., Crystal R.G. Therapeutic angiogenesis: protein and gene therapy delivery strategies. J Cardiovas Risk. 6:1999;29-40.
3. Task Force website at http://www.chd-taskforce.com.
4. Bussolino F., Mantovani A., Persico G. Molecular mechanisms of blood vessel formation. Trends Biotechnol. 22:1997;251-256.
5. Carmeliet P., Collen D. Vascular development and disorders - molecular analysis and pathogenic insights. Kid Int. 53:1998;1519-1549.
6. Hertig A.T. Angiogenesis in the early human chorion and in the primary placenta of the macaque monkey. Contrib Embryol Carnegie Inst. 25:1935;37-43.
7. Folkman J. Tumor angiogenesis: therapeutic implications (review). New Engl J Med. 285:1971;1182-1186.
8. Risau W. Mechanisms of angiogenesis. Nature. 386:1997;671-674.
9. Battegay E.J. Angiogenesis - mechanistic insights, neovascular diseases, and therapeutic prospects. J Mol Med. 73:1995;333-346.
10. Clauss M. Functions of the VEGF receptor-1 (FLT-1) in the vasculature. Trends Cardiovas Med. 8:1998;241-245. This review focuses on the role of vascular endothelial growth factor in the vasculature and the role of the VEGF receptors in this scenario.
11. Clauss M., Weich H., Breier G., Knies U., Rockl W., Waltenberger J., Risau W. The vascular endothelial growth factor receptor FLT-1 mediates biological activities - implications for a functional role of placenta growth factor in monocyte activation and chemotaxis. J Biol Chem. 271:1996;17629-17634.
12. Ferrara N. Role of vascular endothelial growth factor in the regulation of angiogenesis. Kid Int. 56:1999;794-814.
13. Ferrara N., Carvermoore K., Chen H., Dowd M., Lu L., Oshea K.S., Powellbraxton L., Hillan K.J., Moore M.W. Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene. Nature. 380:1996;439-442.
14. Arras M., Ito W.D., Scholz D., Winkler B., Schaper J., Schaper W. Monocyte activation in angiogenesis and collateral growth in the rabbit hindlimb. J Clin Invest. 101:1998;40-50.
15. Ito W.D., Arras M., Scholz D., Winkler B., Htun P., Schaper W. Angiogenesis but not collateral growth is associated with ischemia after femoral artery occlusion. Am J Physiol. 42:1997;H1255-H1265.
16. Ito W.D., Arras M., Winkler B., Scholz D., Schaper J., Schaper W. Monocyte chemotactic protein-1 increases collateral and peripheral conductance after femoral artery occlusion. Circ Res. 80:1997;829-837.
17. Schaper W., Buschmann I. Arteriogenesis, the good and bad of it. Cardiovas Res. 43:1999;835-837.
18. Buschmann I., Schaper W. Arteriogenesis versus angiogenesis: two mechanisms of vessel growth. News Physiol Sci. 14:1999;121-125.
19. Longland C.J. The collateral circulation of the limb. Ann R Coll Surg Engl. 13:1931;161-164.
20. Schaper W., Buschmann I. Collateral circulation and diabetes. Circulation. 99:1999;2224-2226.
21. Shyy Y.-J, Hsieh H.-J., Usami S., Chien S. Fluid shear stress induces a biphasic response of human monocyte chemotactic protein 1 expression in vascular endothelium. Proc Natl Acad Sci USA. 91:1994;4678-4682.
22. Kosaki K., Ando J., Korenaga R., Kurokawa T., Kamiya A. Fluid shear stress increases the production of granulocyte-macrophage colony-stimulating factor by endothelial cells via mRNA stabilization. Circ Res. 82:1998;794-802.
23. Buschmann IR, Heil M, Hoefer IE, Katzer E, van Royen N, Fischer S, Piek JJ, Schaper W: Role of colony stimulating factors during arteriogenesis (growth of collateral arteries). Circ 1999, (suppl):in press.
24. Kurjak A., Kupesic S. : Three dimensional ultrasound and power Doppler in assessment of uterine and ovarian angiogenesis: prospective study. Croatian Med J. 40:1999;413-420.