Identification of an angiogenic mitogen selective for endocrine gland endothelium

Nature

Volumn 412, Issue 6850, 2001, Pages 877-884

  Lecouter, Jennifer ^a   Kowalski, Joe ^a   Foster, Jessica ^b   Hass, Phil ^b   Zhang, Zemin ^b   Dillard Telm, Lisa ^b   Frantz, Gretchen ^b   Rangell, Linda ^b   Deguzman, Leo ^a   Keller, Gilbert Andre ^b   Peale, Franklin ^b   Gurney, Austin ^b   Hillan, Kenneth J ^b   Ferrara, Napoleone ^a  

^a Department of Molecular Oncology ^*  (United States)

^b GENENTECH INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROLIFERATION;

CAPILLARITY; CELLS; MUSCLE; RNA; TISSUE;

ANGIOGRAPHY;

ENDOCRINE GLAND DERIVED VASCULAR ENDOTHELIAL GROWTH FACTOR; HYPOXIA INDUCIBLE FACTOR 1; MITOGENIC AGENT; UNCLASSIFIED DRUG; VASCULOTROPIN;

BIOCHEMISTRY; BIOLOGY;

ADRENAL GLAND; ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING SITE; CAPILLARY WALL; CELL DIFFERENTIATION; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; CORNEA; ENDOCRINE GLAND; FENESTRATION; GENE EXPRESSION REGULATION; HUMAN; HYPOXIA; MOUSE; NONHUMAN; OVARY; PLACENTA; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN LOCALIZATION; RAT; SKELETAL MUSCLE; TESTIS; TISSUE SPECIFICITY; VASCULAR ENDOTHELIUM;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CATTLE; CELL HYPOXIA; CELLS, CULTURED; DISEASE MODELS, ANIMAL; DNA, COMPLEMENTARY; ENDOCRINE GLANDS; ENDOTHELIAL GROWTH FACTORS; ENDOTHELIUM, VASCULAR; FEMALE; GASTROINTESTINAL HORMONES; GENE EXPRESSION REGULATION; HUMANS; LYMPHOKINES; MICE; MICE, NUDE; MITOGENS; MOLECULAR SEQUENCE DATA; NEOVASCULARIZATION, PHYSIOLOGIC; OVARIAN CYSTS; RATS; RECOMBINANT FUSION PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; TISSUE DISTRIBUTION; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTOR, ENDOCRINE-GLAND-DERIVED; VASCULAR ENDOTHELIAL GROWTH FACTORS;

ANIMALIA;

EID: 0035974803     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/35091000     Document Type: Article

References (46)

1. Angiogenesis in cancer, vascular, rheumatoid and other disease
2. Clinical applications of angiogenic growth factors and their inhibitors
3. Mechanisms of angiogenesis and arteriogenesis
4. Vascular-specific growth factors and blood vessel formation
5. Developing nervous tissue induces formation of blood-brain barrier characteristics in invading endothelial cells: A study using quail-chick transplantation chimeras
6. Vascular bed-specific expression of an endothelial cell gene is programmed by the tissue microenvironment
7. Quantitation and physiological characterization of angiogenic vessels in mice: Effect of basic fibroblast growth factor, vascular endothelial growth factor/vascular permeability factor, and host microenvironment
8. Structural aspects of the permeability of the microvascular endothelium
9. Expression of vascular endothelial growth factor during embryonic angiogenesis and endothelial cell differentiation
10. Expression of vascular permeability factor/vascular endothelial growth factor in normal rat tissues
11. Vascular endothelial growth factor is a secreted angiogenic mitogen
12. Snake venom. The amino acid sequence of protein A from Dendroaspis polylepis polylepis (black mamba) venom
13. A structural homologue of colipase in black mamba venom revealed by NMR floating disulphide bridge analysis
14. The mammalian homologues of frog Bv8 are mainly expressed in spermatocytes
15. Dickkopf-1 is a member of a new family of secreted proteins and functions in head induction
16. A colipase fold in the carboxy-terminal domain of the Wnt antagoniststhe Dickkopfs
17. Mediators of angiogenesis: The biological significance of basic fibroblast growth factor (bFGF)-heparin and heparan sulfate interactions
18. Migration of capillary endothelial cells is stimulated by tumour-derived factors
19. Oncogenic H-ras stimulates tumor angiogenesis by two distinct pathways
20. Neovasculature induced by vascular endothelial growth factor is fenestrated
21. Vascular endothelial growth factor induces endothelial fenestrations in vitro
22. Comparison of the ability of basement membranes produced by corneal endothelial and mouse-derived endodermal PF-HR-9 cells to support the proliferation and differentiation of bovine kidney tubule epithelial cells in vitro
23. HIF-1: Mediator of physiological and pathophysiological response to hypoxia
24. Vascular endothelial growth factor and vascular adjustments to perturbations in oxygen homeostasis
25. Leydig cells secrete factors which increase vascular permeability and endothelial cell proliferation
26. The changes in the vascular pattern of the ovary of the albino rat during the estrous cycle
27. Vascular endothelial growth factor messenger ribonucleic acid expression in the primate ovary
28. The polycistic ovary. I. Clinical and histologic features
29. Vascular endothelial growth factor is expressed in rat corpus luteum
30. Heterogeneity of the angiogenic response induced in different normal adult tissues by vascular permeability factor/vascular endothelial growth factor
31. Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene
32. VEGF is required for growth and survival in neonatal mice
33. Vascular endothelial growth factor is essential for corpus luteum angiogenesis
34. VEGF couples hypertrophic cartilage remodeling, ossification and angiogenesis during endochondral bone formation
35. Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses turnout growth in vivo
36. Vascular endothelial growth factor in ocular fluid of patients with diabetic retinopathy and other retinal disorders
37. VEGF: An update on biological and therapeutic aspects
38. Preclinical safety evaluation of rhuMAbVEGF, an antiangiogenic humanized monoclonal antibody
39. Neuropilin-I mediates collapsin-1/semaphorin III inhibition of endothelial cell motility: Functional competition of collapsin-1 and vascular endothelial growth factor-165
40. MIT(1), a black mamba intestinal toxin with a new and highly potent activity on intestinal contraction
41. Widespread expression of BDNF but not NT 3 by target areas of basal forebrain cholinergic neurons
42. Efficient in vitro synthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter
43. Analysis of biological effects and signaling properties of Flt-1 (VEGFR-1) and KDR (VEGFR-2). A reassessment using novel receptor-specific VEGF mutants
44. Functional and structural diversity of the human Dickkopf gene family
45. Structure of the pancreatic lipase-procolipase complex