COP9 signalosome-specific phosphorylation targets p53 to degradation by the ubiquitin system

EMBO Journal

Volumn 20, Issue 7, 2001, Pages 1630-1639

  Bech Otschir, Dawadschargal ^a   Kraft, Regine ^b   Huang, Xiaohua ^a   Henklein, Peter ^a   Kapelari, Barbara ^c   Pollmann, Christian ^a   Dubiel, Wolfgang ^a  

^a HUMBOLDT UNIVERSITY   (Germany)

^b MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^c MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

Author keywords

COP9 signalosome; Jab1; Mdm2; Proteasome; Ubiquitin

Indexed keywords

COP9 SIGNALOSOME; CURCUMIN; PROTEASOME; PROTEIN MDM2; PROTEIN P21; PROTEIN P53; THREONINE; UBIQUITIN; UNCLASSIFIED DRUG; VALINE;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; ELECTRON MICROSCOPY; HUMAN; HUMAN CELL; INHIBITION KINETICS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; RETICULOCYTE LYSATE;

AMINO ACID SEQUENCE; BINDING SITES; DNA; DNA-BINDING PROTEINS; HELA CELLS; HL-60 CELLS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MOLECULAR SEQUENCE DATA; MULTIPROTEIN COMPLEXES; MUTAGENESIS, SITE-DIRECTED; PEPTIDE HYDROLASES; PHOSPHORYLATION; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEINS; PROTO-ONCOGENE PROTEINS P21(RAS); SIGNAL TRANSDUCTION; THREONINE; TRANSCRIPTION FACTORS; TUMOR SUPPRESSOR PROTEIN P53; UBIQUITINS; VALINE;

EUKARYOTA; HUMAN PAPILLOMA VIRUS; MINK CELL FOCUS-FORMING VIRUS; PAPILLOMAVIRUS;

EID: 0035794541     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/20.7.1630     Document Type: Article

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