Prospects for targeting the Bcl-2 family of proteins to develop novel cytotoxic drugs

Biochemical Pharmacology

Volumn 64, Issue 5-6, 2002, Pages 851-863

  Baell, Jonathan B ^a   Huang, David C S ^a  

^a ROYAL MELBOURNE HOSPITAL   (Australia)

Author keywords

Apoptosis; Bcl 2; BH3; Cancer; Drug design

Indexed keywords

ANTINEOPLASTIC AGENT; BH3 PROTEIN; CYTOTOXIC AGENT; PROTEIN BCL 2; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER; CANCER CHEMOTHERAPY; CELL DEATH; HUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; ANIMALS; APOPTOSIS; CELLS, CULTURED; HUMANS; MODELS, MOLECULAR; MOLECULAR MIMICRY; MOLECULAR SEQUENCE DATA; PROTEIN STRUCTURE, TERTIARY; PROTO-ONCOGENE PROTEINS C-BCL-2; SEQUENCE HOMOLOGY, AMINO ACID; SIGNAL TRANSDUCTION;

EID: 0036710477     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(02)01148-6     Document Type: Article

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