-
1
-
-
0032575688
-
The Bcl-2 protein family: Arbiters of cell survival
-
Adams J.M., Cory S. The Bcl-2 protein family. arbiters of cell survival Science. 281:1998;1322-1326.
-
(1998)
Science
, vol.281
, pp. 1322-1326
-
-
Adams, J.M.1
Cory, S.2
-
2
-
-
0035146929
-
Life-or-death decisions by the Bcl-2 protein family
-
Adams J.M., Cory S. Life-or-death decisions by the Bcl-2 protein family. Trends Biochem. Sci. 26:2001;61-66.
-
(2001)
Trends Biochem. Sci.
, vol.26
, pp. 61-66
-
-
Adams, J.M.1
Cory, S.2
-
3
-
-
0031587826
-
Bcl-2 rescues T lymphopoiesis in interleukin-7 receptor-deficient mice
-
Akashi K., Kondo M., von Freeden-Jeffry U., Murray R., Weissman I.L. Bcl-2 rescues T lymphopoiesis in interleukin-7 receptor-deficient mice. Cell. 89:1997;1033-1041.
-
(1997)
Cell
, vol.89
, pp. 1033-1041
-
-
Akashi, K.1
Kondo, M.2
Von Freeden-Jeffry, U.3
Murray, R.4
Weissman, I.L.5
-
4
-
-
0035853811
-
Bax is present as a high molecular weight oligomer/complex in the mitochondrial membrane of apoptotic cells
-
Antonsson B., Montessuit S., Sanchez B., Martinou J.C. Bax is present as a high molecular weight oligomer/complex in the mitochondrial membrane of apoptotic cells. J. Biol. Chem. 276:2001;11615-11623.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 11615-11623
-
-
Antonsson, B.1
Montessuit, S.2
Sanchez, B.3
Martinou, J.C.4
-
5
-
-
0033607506
-
Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity
-
Bouillet P., Metcalf D., Huang D.C.S., Tarlinton D.M., Kay T.W.H., Köntgen F., Adams J.M., Strasser A. Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity. Science. 286:1999;1735-1738.
-
(1999)
Science
, vol.286
, pp. 1735-1738
-
-
Bouillet, P.1
Metcalf, D.2
Huang, D.C.S.3
Tarlinton, D.M.4
Kay, T.W.H.5
Köntgen, F.6
Adams, J.M.7
Strasser, A.8
-
6
-
-
0035124927
-
Gene structure alternative splicing, and chromosomal localization of pro-apoptotic Bcl-2 relative Bim
-
Bouillet P., Zhang L.C., Huang D.C., Webb G.C., Bottema C.D., Shore P., Eyre H.J., Sutherland G.R., Adams J.M. Gene structure alternative splicing, and chromosomal localization of pro-apoptotic Bcl-2 relative Bim. Mamm. Genome. 12:2001;163-168.
-
(2001)
Mamm. Genome
, vol.12
, pp. 163-168
-
-
Bouillet, P.1
Zhang, L.C.2
Huang, D.C.3
Webb, G.C.4
Bottema, C.D.5
Shore, P.6
Eyre, H.J.7
Sutherland, G.R.8
Adams, J.M.9
-
7
-
-
0034712042
-
Translocation of C. elegans CED-4 to nuclear membranes during programmed cell death
-
Chen F., Hersh B.M., Conradt B., Zhou Z., Riemer D., Gruenbaum Y., Horvitz H.R. Translocation of C. elegans CED-4 to nuclear membranes during programmed cell death. Science. 287:2000;1485-1489.
-
(2000)
Science
, vol.287
, pp. 1485-1489
-
-
Chen, F.1
Hersh, B.M.2
Conradt, B.3
Zhou, Z.4
Riemer, D.5
Gruenbaum, Y.6
Horvitz, H.R.7
-
8
-
-
0034786019
-
Bcl-2, bcl-x(l) sequester bh3 domain-only molecules preventing bax- And bak-mediated mitochondrial apoptosis
-
Cheng E.H., Wei M.C., Weiler S., Flavell R.A., Mak T.W., Lindsten T., Korsmeyer S.J. Bcl-2, bcl-x(l) sequester bh3 domain-only molecules preventing bax- and bak-mediated mitochondrial apoptosis. Mol. Cell. 8:2001;705-711.
-
(2001)
Mol. Cell
, vol.8
, pp. 705-711
-
-
Cheng, E.H.1
Wei, M.C.2
Weiler, S.3
Flavell, R.A.4
Mak, T.W.5
Lindsten, T.6
Korsmeyer, S.J.7
-
9
-
-
0027205529
-
Large-scale normal cell death in the developing rat kidney and its reduction by epidermal growth factor
-
Coles H.S., Burne J.F., Raff M.C. Large-scale normal cell death in the developing rat kidney and its reduction by epidermal growth factor. Development. 118:1993;777-784.
-
(1993)
Development
, vol.118
, pp. 777-784
-
-
Coles, H.S.1
Burne, J.F.2
Raff, M.C.3
-
10
-
-
0032524885
-
The C. elegans protein EGL-1 is required for programmed cell death and interacts with the Bcl-2-like protein CED-9
-
Conradt B., Horvitz H.R. The C. elegans protein EGL-1 is required for programmed cell death and interacts with the Bcl-2-like protein CED-9. Cell. 93:1998;519-529.
-
(1998)
Cell
, vol.93
, pp. 519-529
-
-
Conradt, B.1
Horvitz, H.R.2
-
11
-
-
0033179760
-
Bcl-2 family members and the mitochondria in apoptosis
-
Gross A., McDonnell J.M., Korsmeyer S.J. Bcl-2 family members and the mitochondria in apoptosis. Genes Dev. 13:1999;1899-1911.
-
(1999)
Genes Dev.
, vol.13
, pp. 1899-1911
-
-
Gross, A.1
McDonnell, J.M.2
Korsmeyer, S.J.3
-
12
-
-
0033635733
-
BH3-only protein-essential initiators of apoptotic cell death
-
Huang D.C.S., Strasser A. BH3-only protein-essential initiators of apoptotic cell death. Cell. 103:2000;839-842.
-
(2000)
Cell
, vol.103
, pp. 839-842
-
-
Huang, D.C.S.1
Strasser, A.2
-
13
-
-
0028833859
-
Bcl-2 deficiency in mice leads to pleiotropic abnormalities: Accelerated lymphoid cell death in thymus and spleen, polycystic kidney, hair hypopigmentation, and distorted small intestine
-
Kamada S., Shimono A., Shinto Y., Tsujimura T., Takahashi T., Noda T., Kitamura Y., Kondoh H., Tsujimoto Y. bcl-2 deficiency in mice leads to pleiotropic abnormalities. accelerated lymphoid cell death in thymus and spleen, polycystic kidney, hair hypopigmentation, and distorted small intestine Cancer Res. 55:1995;354-359.
-
(1995)
Cancer Res.
, vol.55
, pp. 354-359
-
-
Kamada, S.1
Shimono, A.2
Shinto, Y.3
Tsujimura, T.4
Takahashi, T.5
Noda, T.6
Kitamura, Y.7
Kondoh, H.8
Tsujimoto, Y.9
-
15
-
-
0032922711
-
Bcl-2 overexpression prevents apoptosis-induced Madin-Darby canine kidney simple epithelial cyst formation
-
Lin H.H., Yang T.P., Jiang S.T., Yang H.Y., Tang M.J. Bcl-2 overexpression prevents apoptosis-induced Madin-Darby canine kidney simple epithelial cyst formation. Kidney Int. 55:1999;168-178.
-
(1999)
Kidney Int.
, vol.55
, pp. 168-178
-
-
Lin, H.H.1
Yang, T.P.2
Jiang, S.T.3
Yang, H.Y.4
Tang, M.J.5
-
16
-
-
0034508217
-
The combined functions of proapoptotic Bcl-2 family members Bak and Bax are essential for normal development of multiple tissues
-
Lindsten T., Ross A.J., King A., Zong W., Rathmell J.C., Shiels H.A., Ulrich E., Waymire K.G., Mahar P., Frauwirth K.et al. The combined functions of proapoptotic Bcl-2 family members Bak and Bax are essential for normal development of multiple tissues. Mol. Cell. 6:2000;1389-1399.
-
(2000)
Mol. Cell
, vol.6
, pp. 1389-1399
-
-
Lindsten, T.1
Ross, A.J.2
King, A.3
Zong, W.4
Rathmell, J.C.5
Shiels, H.A.6
Ulrich, E.7
Waymire, K.G.8
Mahar, P.9
Frauwirth, K.10
-
17
-
-
0029031937
-
Bclx regulates the survival of double-positive thymocytes
-
Ma A., Pena J.C., Chang B., Margosian E., Davidson L., Alt F.W., Thompson C.B. Bclx regulates the survival of double-positive thymocytes. Proc. Natl. Acad. Sci. USA. 92:1995;4763-4767.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 4763-4767
-
-
Ma, A.1
Pena, J.C.2
Chang, B.3
Margosian, E.4
Davidson, L.5
Alt, F.W.6
Thompson, C.B.7
-
19
-
-
0030893390
-
Role of bcl-2 in the development of lymphoid cells from the hematopoietic stem cell
-
Matsuzaki Y., Nakayama K.-I., Nakayama K., Tomita T., Isoda M., Loh D.Y., Nakauchi H. Role of bcl-2 in the development of lymphoid cells from the hematopoietic stem cell. Blood. 89:1997;853-862.
-
(1997)
Blood
, vol.89
, pp. 853-862
-
-
Matsuzaki, Y.1
Nakayama, K.-I.2
Nakayama, K.3
Tomita, T.4
Isoda, M.5
Loh, D.Y.6
Nakauchi, H.7
-
20
-
-
0035947596
-
Bcl-2 prevents bax oligomerization in the mitochondrial outer membrane
-
Mikhailov V., Mikhailova M., Pulkrabek D.J., Dong Z., Venkatachalam M.A., Saikumar P. Bcl-2 prevents bax oligomerization in the mitochondrial outer membrane. J. Biol. Chem. 276:2001;18361-18374.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 18361-18374
-
-
Mikhailov, V.1
Mikhailova, M.2
Pulkrabek, D.J.3
Dong, Z.4
Venkatachalam, M.A.5
Saikumar, P.6
-
21
-
-
0034059440
-
Bcl-2 inhibits Bax translocation from cytosol to mitochondria during drug-induced apoptosis of human tumor cells
-
Murphy K.M., Ranganathan V., Farnsworth M.L., Kavallaris M., Lock R.B. Bcl-2 inhibits Bax translocation from cytosol to mitochondria during drug-induced apoptosis of human tumor cells. Cell Death Differ. 7:2000;102-111.
-
(2000)
Cell Death Differ.
, vol.7
, pp. 102-111
-
-
Murphy, K.M.1
Ranganathan, V.2
Farnsworth, M.L.3
Kavallaris, M.4
Lock, R.B.5
-
22
-
-
0029928192
-
Apoptosis during an early stage of nephrogenesis induces renal hypoplasia in bcl-2-deficient mice
-
Nagata M., Nakauchi H., Nakayama K.-I., Nakayama K., Loh D., Watanabe T. Apoptosis during an early stage of nephrogenesis induces renal hypoplasia in bcl-2-deficient mice. Am. J. Pathol. 148:1996;1601-1611.
-
(1996)
Am. J. Pathol.
, vol.148
, pp. 1601-1611
-
-
Nagata, M.1
Nakauchi, H.2
Nakayama, K.-I.3
Nakayama, K.4
Loh, D.5
Watanabe, T.6
-
23
-
-
0028175759
-
Targeted disruption of bcl-2αβ in mice: Occurrence of gray hair, polycystic kidney disease, and lymphocytopenia
-
Nakayama K., Nakayama K.-I., Negishi I., Kuida K., Sawa H., Loh D.Y. Targeted disruption of bcl-2αβ in mice. occurrence of gray hair, polycystic kidney disease, and lymphocytopenia Proc. Natl. Acad. Sci. USA. 91:1994;3700-3704.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 3700-3704
-
-
Nakayama, K.1
Nakayama, K.-I.2
Negishi, I.3
Kuida, K.4
Sawa, H.5
Loh, D.Y.6
-
24
-
-
0032518787
-
Bim: A novel member of the Bcl-2 family that promotes apoptosis
-
O'Connor L., Strasser A., O'Reilly L.A., Hausmann G., Adams J.M., Cory S., Huang D.C.S. Bim. a novel member of the Bcl-2 family that promotes apoptosis EMBO J. 17:1998;384-395.
-
(1998)
EMBO J.
, vol.17
, pp. 384-395
-
-
O'Connor, L.1
Strasser, A.2
O'Reilly, L.A.3
Hausmann, G.4
Adams, J.M.5
Cory, S.6
Huang, D.C.S.7
-
25
-
-
0034710971
-
Demonstration of the in vivo interaction of key cell death regulators by structure-based design of second-site suppressors
-
Parrish J., Metters H., Chen L., Xue D. Demonstration of the in vivo interaction of key cell death regulators by structure-based design of second-site suppressors. Proc. Natl. Acad. Sci. USA. 97:2000;11916-11921.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 11916-11921
-
-
Parrish, J.1
Metters, H.2
Chen, L.3
Xue, D.4
-
26
-
-
0033549754
-
The biology of hair follicles
-
Paus R., Cotsarelis G. The biology of hair follicles. N. Engl. J. Med. 341:1999;491-497.
-
(1999)
N. Engl. J. Med.
, vol.341
, pp. 491-497
-
-
Paus, R.1
Cotsarelis, G.2
-
27
-
-
0035053624
-
Induction of Bim, a proapoptotic BH3-only Bcl-2 family member, is critical for neuronal apoptosis
-
Putcha G.V., Moulder K.L., Golden J.P., Bouillet P., Adams J.M., Strasser A., Johnson E.M.J. Induction of Bim, a proapoptotic BH3-only Bcl-2 family member, is critical for neuronal apoptosis. Neuron. 29:2001;615-628.
-
(2001)
Neuron
, vol.29
, pp. 615-628
-
-
Putcha, G.V.1
Moulder, K.L.2
Golden, J.P.3
Bouillet, P.4
Adams, J.M.5
Strasser, A.6
Johnson, E.M.J.7
-
29
-
-
0029566108
-
A cre-transgenic mouse strain for the ubiquitous deletion of loxP-flanked gene segments including deletion in germ cells
-
Schwenk F., Baron U., Rajewsky K. A cre-transgenic mouse strain for the ubiquitous deletion of loxP-flanked gene segments including deletion in germ cells. Nucleic Acids Res. 23:1995;5080-5081.
-
(1995)
Nucleic Acids Res.
, vol.23
, pp. 5080-5081
-
-
Schwenk, F.1
Baron, U.2
Rajewsky, K.3
-
30
-
-
0028887385
-
Fulminant metanephric apoptosis and abnormal kidney development in bcl-2-deficient mice
-
Sorenson C.M., Rogers S.A., Korsmeyer S.J., Hammerman M.R. Fulminant metanephric apoptosis and abnormal kidney development in bcl-2-deficient mice. Am. J. Physiol. 268:1995;F73-F81.
-
(1995)
Am. J. Physiol.
, vol.268
-
-
Sorenson, C.M.1
Rogers, S.A.2
Korsmeyer, S.J.3
Hammerman, M.R.4
-
31
-
-
0025786164
-
Bcl-2 transgene inhibits T cell death and perturbs thymic self-censorship
-
Strasser A., Harris A.W., Cory S. Bcl-2 transgene inhibits T cell death and perturbs thymic self-censorship. Cell. 67:1991;889-899.
-
(1991)
Cell
, vol.67
, pp. 889-899
-
-
Strasser, A.1
Harris, A.W.2
Cory, S.3
-
33
-
-
0027427492
-
Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair
-
Veis D.J., Sorenson C.M., Shutter J.R., Korsmeyer S.J. Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair. Cell. 75:1993;229-240.
-
(1993)
Cell
, vol.75
, pp. 229-240
-
-
Veis, D.J.1
Sorenson, C.M.2
Shutter, J.R.3
Korsmeyer, S.J.4
-
34
-
-
0029681851
-
Accelerated disappearance of melanocytes in bcl-2-deficient mice
-
Yamamura K., Kamada S., Ito S., Nakagawa K., Ichihashi M., Tsujimoto Y. Accelerated disappearance of melanocytes in bcl-2-deficient mice. Cancer Res. 56:1996;3546-3550.
-
(1996)
Cancer Res.
, vol.56
, pp. 3546-3550
-
-
Yamamura, K.1
Kamada, S.2
Ito, S.3
Nakagawa, K.4
Ichihashi, M.5
Tsujimoto, Y.6
-
35
-
-
0035154832
-
Death by design: The big debut of small molecules
-
Zheng T.S. Death by design. the big debut of small molecules Nat. Cell Biol. 3:2001;E43-E46.
-
(2001)
Nat. Cell Biol.
, vol.3
-
-
Zheng, T.S.1
-
36
-
-
0035876483
-
BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak
-
Zong W.X., Lindsten T., Ross A.J., MacGregor G.R., Thompson C.B. BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak. Genes Dev. 15:2001;1481-1486.
-
(2001)
Genes Dev.
, vol.15
, pp. 1481-1486
-
-
Zong, W.X.1
Lindsten, T.2
Ross, A.J.3
MacGregor, G.R.4
Thompson, C.B.5
|