Bak BH3 peptides antagonize Bcl-x(L) function and induce apoptosis through cytochrome c-independent activation of caspases

Journal of Biological Chemistry

Volumn 274, Issue 19, 1999, Pages 13298-13304

  Holinger, Eric P ^a   Chittenden, Thomas ^a   Lutz, Robert J ^a  

^a Apoptosis Technology Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE; CYTOCHROME C; PROTEIN BCL 2;

AMINO ACID SEQUENCE; APOPTOSIS; ARTICLE; ENZYME ACTIVATION; ENZYME LOCALIZATION; HELA CELL; HUMAN; HUMAN CELL; MITOCHONDRION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PROTEIN INTERACTION; SEQUENCE HOMOLOGY;

ANTENNAPEDIA HOMEODOMAIN PROTEIN; APOPTOSIS; BCL-2 HOMOLOGOUS ANTAGONIST-KILLER PROTEIN; BCL-X PROTEIN; CASPASES; CYTOCHROME C GROUP; ENZYME ACTIVATION; HELA CELLS; HOMEODOMAIN PROTEINS; HUMANS; MEMBRANE PROTEINS; MITOCHONDRIA; NUCLEAR PROTEINS; PEPTIDE FRAGMENTS; PROTO-ONCOGENE PROTEINS C-BCL-2; RECOMBINANT FUSION PROTEINS; TRANSCRIPTION FACTORS;

EID: 0033531926     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.19.13298     Document Type: Article

References (59)

1. Reed, J. C. (1997) Nature 387, 773-776
2. Yin, X.-M., Oltvai, Z. N., and Korsmeyer, S. J. (1994) Nature 389, 321-323
3. Sattler, M., Liang, H., Nettesheim, D., Meadows, R. P., Harlan, J. E., Eberstadt, M., Yoon, H. S., Shuker, S. B., Chang, B. S., Minn, A. J., Thompson, C. B., and Fesik, S. W. (1997) Science 275, 983-986
4. Huang, D. C., Adams, J. M., and Cory, S. (1998) EMBO J. 17, 1029-1039
5. Hanada, M., Aime-Sempe, C., Sato, T., and Reed, J. C. (1995) J. Biol. Chem. 270, 11962-11969
6. Chittenden, T., Flemington, C., Houghton, A. B., Ebb, R. G., Gallo, G. J., Elangovan, B., Chinnadurai, G., and Lutz, R. J. (1995) EMBO J. 14, 5589-5596
7. Zha, H., and Reed, J. C. (1997) J. Biol. Chem. 272, 31482-31488
8. Boyd, J. M., Gallo, G. J., Elangovan, B., Houghton, A. B., Malstrom, S., Avery, B. J., Subramanian, T., Chittenden, T., Lutz, R. J., and Chinnadurai, G. (1995) Oncogene 11, 1921-1928
9. Zha, J., Harada, H., Osipov, K., Jockel, J., Waksman, G., and Korsmeyer, S. J. (1997) J. Biol. Chem. 272, 24101-24104
10. Cosulich, S. C., Worrall, V., Hedge, P. J., Green, S., and Clarke, P. R. (1997) Curr. Biol. 7, 913-920
11. Diaz, J.-L., Oltersdorf, T., Horne, W., McConnell, M., Wilson, G., Weeks, S., Garcia, T., and Fritz, L. C. (1997) J. Biol. Chem. 272, 11350-11355
12. Ottilie, S., Wang, Y., Banks, S., Chang, J., Vigna, N. J., Weeks, S., Armstrong, R. C., Fritz, L. C., and Osterdorf, T. (1997) Cell Death Differ. 4, 526-633
13. Kelekar, A., Chang, B. S., Harlan, J. E., Fesik, S. W., and Thompson, C. B. (1997) Mol. Cell. Biol. 17, 7040-7046
14. Ottilie, S., Diaz, J. L., Horne, W., Chang, J., Wang, Y., Wilson, G., Chang, S., Weeks, S., Fritz, L. C., and Oltersdorf, T. (1997) J. Biol. Chem. 272, 30866-30872
15. Theodore, L., Derossi, D., Chassaing, G., Llirbat, B., Kubes, M., Jordan, P., Chneiweiss, H., Godement, P., and Prochaintz, A. (1996) J. Neurosci. 15, 7158-7167
16. Ball, K. L., Lain, S., Fahraeus, R., Smythe, C., and Lane, D. P. (1996) Curr. Biol. 7, 71-80
17. Bonfanti, M., Taverna, S., Salmona, M., D'Incalci, M., and Broggini, M. (1997) Cancer Res. 57, 1442-1446
18. Fahraeus, R., Paramio, J. M., Ball, K. L., Lain, S., and Lane, D. P. (1996) Curr. Biol. 6, 84-91
19. Selivanova, G., Iotsova, V., Okan, I., Fritsche, M., Strom, M., Groner, B., Grafstrom, R. C., and Wiman, K. G. (1997) Nat. Med. 3, 632-638
20. Williams, E. J., Dunican, D. J., Green, P. J., Howell, F. V., Derossi, D., Walsh, F. S., and Doherty, P. (1997) J. Biol. Chem. 272, 22349-22354
21. Hall, H., Williams, E. J., Moore, S. E., Walsh, F. S., Prochiantz, A., and Doherty, P. (1996) Curr. Biol. 6, 580-587
22. Salvesen, G. S., and Dixit, V. M. (1997) Cell 91, 443-446
23. Kaufmann, S. H., Desnoyers, S., Ottaviano, Y., Davidson, N. E., and Poirier, G. G. (1993) Cancer Res. 53, 3976-3985
24. Tewari, M., Quan, L. T., O'Rourke, K., Desnoyers, S., Zeng, Z., Beidler, D. R., Poirier, G. G., Salvesen, G. S., and Dixit, V. M. (1995) Cell 81, 801-809
25. Nicholson, D. W., Ambereen, A., Thornberry, N. A., Vaillancourt, J. P., Ding, C. K., Gallant, M., Gareau, Y., Griffin, P. R., Labelle, M., Lazebnik, Y. A., Munday, N. A., Raju, S. M., Smulson, M. E., Yamin, T.-T., Yu, V. L., and Miller, D. K. (1995) Nature 376, 37-43
26. Labeznik, Y. A., Kaufmann, S. H., Desnoyers, S., Poirier, G. G., and Earnshaw, W. C. (1994) Nature 371, 346-347
27. Armstrong, R. C., Aja, T., Xiang, J., Gaur, S., Krebs, J. F., Hoang, K., Bai, X., Korsmeyer, S. J., Karanewsky, D. S., Fritz, L. C., and Tomaselli, K. J. (1996) J. Biol. Chem. 271, 16850-16855
28. Reed, J. C. (1997) Cell 91, 559-562
29. Liu, X., Kim, C. N., Yang, J., Jemmerson, R., and Wang, X. (1996) Cell 86, 147-157
30. Kluck, R. M., Bossy-Wetzel, E., Green, D. R., and Newmeyer, D. D. (1997) Science 275, 1132-1136
31. Yang, J., Liu, X., Bhalla, K., Kim, C. N., Ibrado, A. M., Cai, J., Peng, T. I., Jones, D. P., and Wang, X. (1997) Science 275, 1129-1132
32. Salvioli, S., Ardizzoni, A., Franceschi, C., and Cossarizza, A. (1997) FEBS Lett. 411, 77-82
33. Reers, M., Smiley, S. T., Mottola-Hartshorn, C., Chen, A., Lin, M., and Chen, L. B. (1995) Methods Enzymol. 260, 406-417
34. Broekemeier, K. M., Dempsey, M. E., and Pfeiffer, D. R. (1989) J. Biol. Chem. 264, 7826-7830
35. Li, P., Nijhawan, D., Budihardjo, I., Srinivasula, S. M., Ahmad, M., Alnemri, E. S., and Wang, X. (1997) Cell 91, 479-489
36. Zou, H., Henzel, W. J., Liu, X., Lutschg, A., and Wang, X. (1997) Cell 90, 405-413
37. Hu, Y., Benedict, M. A., Wu, D., Inohara, N., and Nunez, G. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 4386-4391
38. Pan, G., O'Rourke, K., and Dixit, V. M. (1998) J. Biol. Chem. 273, 5841-5845
39. Hegde, R., Srinivasula, S. M., Ahmad, M., Fernandes-Alnemri, T., and Alnemri, E. S. (1998) J. Biol. Chem. 273, 7783-7786
40. O'Connor, L., Strasser, A., O'Reilly, L. A., Hausmann, G., Adams, J. M., Cory, S., and Huang, D. C. (1998) EMBO J. 17, 384-395
41. Inohara, N., Ding, L., Chen, S., and Nunez, G. (1997) EMBO J. 16, 1686-1694
42. Kluck, R. M., Martin, S. J., Hoffman, B. M., Zhou, J. S., Green, D. R., and Newmeyer, D. D. (1997) EMBO J. 16, 4639-4649
43. Chauhan, D., Pandey, P., Ogata, A., Teoh, G., Krett, N., Halgren, R., Rosen, S., Kufe, D., Kharbanda, S., and Anderson, K. (1997) J. Biol. Chem. 272, 29995-29997
44. Adachi, S., Gottlieb, R. A., and Babior, B. M. (1998) J. Biol. Chem. 273, 19892-19894
45. Pastorino, J. G., Chen, S. T., Tafani, M., Snyder, J. W., and Farber, J. L. (1998) J. Biol. Chem. 273, 7770-7775
46. Rosse, T., Olivier, R., Monney, L., Rager, M., Conus, S., Fellay, I., Jansen, B., and Borner, C. (1998) Nature 391, 496-499
47. Xiang, J., Chao, D. T., and Korsmeyer, S. J. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 14559-14653
48. Narita, M., Shimizu, S., Ito, T., Chittenden, T., Lutz, R. J., Matsuda, H., and Tsujimoto, Y. (1999) Proc. Natl. Acad. Sci. U. S. A., 95, 14681-14686
49. Jurgensmeier, J. M., Xie, Z., Deveraux, Q., Ellerby, L., Bredesen, D., and Reed, J. C. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 4997-5002
50. Minn, A. J., Velez, P., Schendel, S. L., Liang, H., Muchmore, S. W., Fesik, S. W., Fill, M., and Thompson, C. B. (1997) Nature 385, 353-357
51. Schendel, S. L., Xie, Z., Montal, M. O., Matsuyama, S., Montal, M., and Reed, J. C. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 5113-5118
52. Schlesinger, P. H., Gross, A., Yin, X. M., Yamamoto, K., Saito, M., Waksman, G., and Korsmeyer, S. J. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 11357-11362
53. Antonsson, B., Conti, F., Ciavatta, A., Montessuit, S., Lewis, S., Martinou, I., Bernasconi, L., Bernard, A., Mermod, J. J., Mazzei, G., Maundrell, K., Gambale, F., Sadoul, R., and Martinou, J. C. (1997) Science 277, 370-372
54. Kitanaka, C., Namiki, T., Noguchi, K., Mochizuki, T., Kagaya, S., Chi, S., Hayashi, A., Asai, A., Taujimoto, Y., and Kuchino, Y. (1997) Oncogene 15, 1763-1772
55. Miller, T. M., Moulder, K. L., Knudson, C. M., Creedon, D. J., Deshmukh, M., Korsmeyer, S. J., and Johnson, E. M., Jr. (1997) J. Cell Biol. 139, 205-217
56. Simonian, P. L., Grillot, D. A., and Nunez, G. (1997) Oncogene 15, 1871-1875
57. Simonian, P. L., Grillot, D. A. M., Merino, R., and Nunez, G. (1996) J. Biol. Chem. 271, 22764-22772
58. Strasser, A., Huang, D. C., and Vaux, D. L. (1997) Biochim. Biophys. Acta 1333, F151-F178
59. Reed, J. C., Miyashita, T., Takayama, S., Wang, H. G., Sato, T., Krajewski, S., Aime-Sempe, C., Bodrug, S., Kitada, S., and Kanada, M. (1996) J. Cell. Biochem. 60, 23-32