Identification of small-molecule inhibitors of interaction between the BH3 domain and Bcl-xL

Nature Cell Biology

Volumn 3, Issue 2, 2001, Pages 173-182

  Degterev, Alexei ^a   Lugovskoy, Alexey ^a,b   Cardone, Michael ^c   Mulley, Bradley ^a   Wagner, Gerhard ^b   Mitchison, Timothy ^a   Yuan, Junying ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b HARVARD UNIVERSITY   (United States)

^c MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BH3 PROTEIN; PROTEIN BCL X; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL MEMBRANE PERMEABILITY; DIMERIZATION; MITOCHONDRIAL MEMBRANE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; RECEPTOR BINDING; STRUCTURE ANALYSIS; TARGET CELL;

APOPTOSIS; BCL-2 HOMOLOGOUS ANTAGONIST-KILLER PROTEIN; BCL-X PROTEIN; BH3 INTERACTING DOMAIN DEATH AGONIST PROTEIN; BLOTTING, WESTERN; CARRIER PROTEINS; CASPASES; CELL LINE; CELL SEPARATION; CYTOCHROME C GROUP; DIMERIZATION; FLOW CYTOMETRY; FLUORESCENCE POLARIZATION; GENES, REPORTER; HUMANS; IN SITU NICK-END LABELING; MAGNETIC RESONANCE SPECTROSCOPY; MEMBRANE PROTEINS; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; PROTO-ONCOGENE PROTEINS C-BCL-2; RECOMBINANT FUSION PROTEINS;

ANIMALIA;

EID: 0035150803     PISSN: 14657392     EISSN: None     Source Type: Journal    
DOI: 10.1038/35055085     Document Type: Article

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