Absence of expression of transforming growth factor-β type II receptor is associated with an aggressive growth pattern in a murine renal carcinoma cell line, Renca

Journal of Urology

Volumn 160, Issue 5, 1998, Pages 1883-1888

  Kundu, Shilajit D ^a   Kim, Isaac Y ^a   Zelner, David ^a   Janulis, Lynn ^a   Goodwin, Shannon ^a   Engel, Jason D ^a   Lee, Chung ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

Author keywords

Murine tumor system; Renal cell carcinoma; TGF receptor; TGF 1

Indexed keywords

TRANSFORMING GROWTH FACTOR BETA2;

ANGIOGENESIS; ANIMAL CELL; ARTICLE; CANCER GROWTH; CELL PROLIFERATION; GENETIC TRANSFECTION; GROWTH INHIBITION; IMMUNE RESPONSE; KIDNEY CARCINOMA; MOUSE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROGNOSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

EID: 0141974555     PISSN: 00225347     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-5347(01)62437-6     Document Type: Article

References (26)

1. Vogelstein, B., Fearon, E. R., Hamilton, S. R., Kern, S. E., Presinger, A. C., Leppert, M., Nakamura, Y., White, R., Smits, A. M. M. and Bos, J. L.: Genetic alterations during colorectal-tumor development. N. Engl. J. Med., 319: 525, 1988.
2. Park, K., Kim, S. J., Bang, Y. J., Park, J. G., Kim, N. K., Roberts, A. B. and Sporn, M. B.: Genetic changes in the transforming growth factor β(TGF-β) type II receptor gene in human gastric cancer cells: correlation with sensitivity to growth inhibition by TGF-β. Proc. Natl. Acad. Sci. USA, 91: 8772, 1994.
3. Sun, L. Z., Wu, G., Wilson, J. K. V., Zbrowska, E., Yang, J., Rajkarunanayake, I., Wang, J., Gentry, L. E., Wang, X. F. and Brittain, M. G.: Expression of transforming growth factor β type I receptor leads to reduced malignancy in human breast cancer MCF-7 cells. J. Biol. Chem., 269: 26449, 1994.
4. Markowitz, S., Wang, J., Meyeroff, L., Parsons, R., Sun, L., Lutterbaugh, J., Fan, R. S., Zbrowska, E., Kinzler, K. W., Vogelstein, B., Brattain, M. and Willson, J. K. V.: Inactivation of the type II TGF-β receptor in colon cancer cells with micro-sattelite instability. Science (Washington D. C.), 268: 1336, 1995.
5. Garrigue-Antar, L., Nunoz-Antonia, T., Antonia, S. J., Gesmonde, J., Velluci, V. F. and Reiss, M.: Missense mutations of the transforming growth factor β type II receptor in human head and neck squamos carcinoma cells. Cancer Res., 55: 3982, 1995.
6. Kalkhoven, E., Roelen, B. A. J., de Winter, J. P., Mummerym C. L., van den Eijnden-van Raaij, A. J. M., van der Saag, P. T. and van der Burg, B.: Resistance to transforming growth factor β and activin due to reduced receptor expression in human breast cancer cell lines. Cell Growth Differ., 6: 1151, 1995.
7. Wang, J., Sun, L. Z., Myeroff, L., Wang, X., Gentry, L. E., Yang, J., Liang, J., Zborowska, E., Markowitz, S., Willson, J. K. V. and Brattain, M. G.: Demonstration that mutation of type II TGF-β receptor inactivates its tumor suppressor in replication error-positive colon carcinoma cells. J. Biol. Chem., 220: 22044, 1995.
8. Gregorian, S. K. and Battisto, J. R.: Immunosuppression in murine renal cell carcinoma. Cancer Immunol. Immunother., 31: 325, 1990.
9. Williams, P. D., Pontes, E. J. and Murphy, G. P.: Studies on the growth of a murine renal cell carcinoma and its metastic patterns. Res. Comm. Chem. Path. Pharm., 34: 345, 1981.
10. Yang, E. Y. and Moses, H. L.: Transforming growth factor β1-induced changes on cell migration, proliferation and angiogenesis in chicken chorioallantoic membrane. J. Cell Biol., 111: 731, 1990.
11. Roberts, A. B., Sporn, M. B., Assoianm R. K., Smith, J. M., Roche, N. S., Wakefield, L. M., Heine, U. I., Liotta, L. A., Falanga, V., Kehrl, J. H. and Fauci, A. S.: Transforming growth factor type β: rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro. Proc. Natl. Sci. USA, 83: 4167, 1986.
12. Kulkarni, A. B., Huh, C. G., Becker, D., Geiser, A., Lyght, M. Flanders, K. C., Roberts, A. B., Sporn, M. B., Ward, J. M. and Karlsson, S.: Transforming growth factor β1 null mutation in mice causes excessive inflammatory response and early death. Proc. Natl. Acad. Sci. USA, 90: 770, 1993.
13. Arrick, B. A., Lopez., A. R., Elfman, F., Ebner, R., Damsky, C. H. and Derynck, R.: Altered metabolic and adhesive properties and increased tumorigenesis associated with increased expression of transforming growth factor beta 1. J. Cell. Biol., 118: 715, 1992.
14. Steiner, M. and Barrack, E. R.: Transforming growth factor-β1 overexpression in prostate cancer: effects on growth in vivo and in vitro. Mol. Endocrinol., 6: 15, 1992.
15. Chang, H. L., Gillet N., Figari, I., Lopez, A. R., Palladino, M. A. and Derynck, R.: Increased transforming growth factor beta expression inhibits cell proliferation in vitro, yet increases tumorigenicity and tumor growth of Meth A sarcoma cells. Cancer Res., 53: 4391, 1993.
16. Eastham, J. A., Truong, L. D., Rogers, E., Kattan M., Flanders, K. C., Scardino, P. T. and Thompson, T. C.: Transforming growth factor-β1: comparative immunohistochemical localization in human primary and metastatic prostate cancer. Lab. Invest., 73: 628, 1995.
17. Lopez-Cassillas, F., Chiefetz, S., Doody, J., Andres, J. L., Lane, W. S. and Massague, J.: Structure and expression of the membrane proteoglycan betaglycan, a component of the TGF-β receptor. Cell, 67: 785, 1991.
18. Lin, H. Y., Wang, X., Ng-Eaton, E., Weinberg, R. A. and Lodish, H. F.: Expression cloning of the TGF-β type II receptor. A functional transmembrane serine/threonine kinase. Cell, 68: 775, 1992.
19. Franzen, P., ten Dijke, P., Ichijo, H., Yamashita, H., Schulz, P., Heldin, C. and Miyazono, K.: Cloning of a TGF-β type I receptor that forms a heteromeric complex with the TGF-β type II receptor. Cell, 75: 681, 1994.
20. Wrana, J. L., Attisano, L., Weiser, R., Ventura, F. and Massague, J.: Mechanism of activation of the TGF-β receptor. Nature (Lond.), 370: 341, 1994.
21. Chen, F. and Weinberg, R. A.: Biochemical evidence for the autophosphorylation and transphosphorylation of transforming growth factor β receptor kinases. Proc. Natl. Acad. Sci. USA, 92: 1565, 1995.
22. Digna, A. and Holldorf, A. W.: Partial purification and characterization of a growth factor from human hyperplastic prostatic tissues. Urol. Res., 20: 133, 1992.
23. Wrana, J., L., Attisano, L., Carcamo, J., Zentella, A., Doody, J., Laiho, M., Wang, X. and Massague, J.: TGF-β signals through a heteromeric protein kinase receptor complex. Cell, 71: 1003, 1992.
24. Steele, R. E. D. and Torrie, J. H.: Principles and Procedures of Statistics. New York: McGraw-Hill Book Company Inc., pp. 91-131, 1960.
25. Kim, I. Y., Ahn, H., Zelner, D. J., Shaw, J. W., Sensibar, J. A., Kim, J., Kato, M. and Lee, C.: Genetic change in transforming growth factor β (TGF-β) receptor type I gene correlates with insensitivity to TGF-β1 in human prostate cancer cells. Cancer Res., 56: 44, 1996.
26. Kim., I. Y., Kim, J., Zelner, D. J., Ahn, H., Sensibar, J., A. and Lee, C.: Transforming growth factor β-1 is a mediator of androgen-regulated growth arrest in an androgen-responsive prostatic cancer cell line, LNCaP. Endocrinol., 137: 991, 1996.