Analyses of microsatellite instability and the transforming growth factor-β receptor type II gene mutation in sporadic human gastrointestinal cancer

Cancer Genetics and Cytogenetics

Volumn 115, Issue 1, 1999, Pages 23-27

  Tomita, Shuji ^a   Miyazato, Hiroshi ^a   Tamai, Osamu ^a   Muto, Yoshihiro ^a   Toda, Takayoshi ^a  

^a UNIVERSITY OF THE RYUKYUS   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

TRANSFORMING GROWTH FACTOR BETA RECEPTOR;

ARTICLE; COLORECTAL CANCER; CONTROLLED STUDY; DIGESTIVE SYSTEM CANCER; ESOPHAGUS CANCER; GENE MUTATION; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MICROSATELLITE INSTABILITY; PRIORITY JOURNAL; SINGLE STRAND CONFORMATION POLYMORPHISM; STOMACH CANCER;

BASE SEQUENCE; CHROMOSOME ABERRATIONS; DNA REPAIR; GASTROINTESTINAL NEOPLASMS; HUMANS; MICROSATELLITE REPEATS; MOLECULAR SEQUENCE DATA; MUTATION; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; SEQUENCE ANALYSIS, DNA;

EID: 0033230455     PISSN: 01654608     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-4608(99)00074-6     Document Type: Article

References (25)

1. Thibodeau S.N., Bren G., Schaid D. Microsatellite instability in cancer of the proximal colon. Science. 260:1993;816-819.
2. Aaltonen L.A., Peltomaki P., Leach S.F., Sistonen P., Pylkkanen L., Mecklin J.-P., Jarvinen H., Powell M.S., Jen J., Hamilton R.S., Petersen M.G., Kinzler W.K., Vogelstein B., Chapelle A. Clues to the pathogenesis of familial colorectal cancer. Science. 260:1993;812-816.
3. Risinger J.I., Berchuck A., Kohler M.F., Watson P., Lynch H., Boyd J. Genetic instability of microsatellites in endometrial carcinoma. Cancer Res. 53:1993;5100-5103.
4. Peltomaki P., Lothe R.A., Aaltonen L.A., Pylkkanen L., Lahti N.M., Seruca R., David L., Holm R., Ryberg D., Haugen A., Brogger A., Borresen A.-L., Chapelle A. Microsatellite instability is associated with tumors that characterize the hereditary non-polyposis colorectal carcinoma syndrome. Cancer Res. 53:1993;5853-5855.
5. Markowitz S., Wang J., Myeroff L., Persons R., Sun L., Lutterbaugh J., Fan S.R., Zborowska E., Kinzler W.K., Vogelstein B., Brattain M., Willson K.V.J. Inactivation of the type II TGF-β receptor in colon cancer cells with microsatellite instability. Science. 268:1994;1336-1338.
6. Wrana J.L., Attisano L., Weiser R., Ventura F., Massague J. Mechanism of activation of the TGF-β receptor. Nature. 370:1994;341-347.
7. Alexandrow M.G., Moses H.L. Transforming growth factor-β and cell cycle regulation. Cancer Res. 55:1995;1452-1457.
8. Park K., Kim S.J., Bang Y., Park J.G., Kim N.K., Roberts A.B., Sporn M.B. Genetic changes in the transforming growth factor β (TGF-β) type II receptor gene in human gastric cancer cells. correlation with sensitivity to growth inhibition by TGF-β Proc Natl Acad Sci. 91:1994;8772-8776.
9. MacKay S.L.D., Yaswen L.R., Tarnuzzer R.W., Moldawer L.L., Bland K.I., Copeland E.M., Schultz G.S. Colon cancer cells that are not growth inhibited by TGF-β lack functional type I and type II TGF-β receptors. Ann Surg. 221:1995;767-777.
10. Lu S.L., Akiyama Y., Nagasaki H., Saitoh K., Yuasa Y. Mutations of the transforming growth factor-β type II receptor gene and genomic instability in hereditary nonpolyposis colorectal cancer. Biochem Biophys Res Commun. 216:1995;452-457.
11. Parsons R., Myeroff L.L., Lui B., Willson J.K., Markowitz S.D., Kinzler K.W., Vogelstein B. Microsatellite instability and mutations of the transforming growth factor-β type II receptor gene in colorectal cancer. Cancer Res. 55:1995;5548-5550.
12. Myeroff L.L., Parsons R., Kim S.J., Hedrick L., Cho K.R., Orth K., Mathis M., Kinzler K.W., Lutterbaugh J., Park K. A transforming growth factor β receptor type II gene mutation common in colon and gastric but rare in endometrial cancers with microsatellite instability. Cancer Res. 55:1995;5545-5547.
13. Vincent F., Hagiwara K., Ke Y., Stoner D.G., Demetrick J.D., Bennett P.W. Mutation analysis of the transforming growth factor β type II receptor in sporadic human cancers of the pancreas, liver, and breast. Biochem Biophys Res Commun. 223:1996;561-564.
14. Hori H., Miyake S., Akiyama Y. Clonal heterogeneity in human esophageal squamous cell carcinomas on DNA analysis. Jpn J Cancer Res. 87:1996;923-929.
15. Togo G., Toda N., Kanai F., Kato N., Shiratori Y., Kishi K., Imazeki F., Makuuchi M., Omata M. A transforming growth factor β type II receptor gene mutation common in sporadic cecum cancer with microsatellite instability. Cancer Res. 56:1996;5620-5623.
16. Souza R.F., Lei J., Yin J., Appel R., Zou T.T., Zhou X., Wang S., Rhyu M.G., Cymes K., Chan O., Park W.S., Krasna M.J., Greenwald B.D., Cottrell J., Abraham J.M., Simms L., Leggett B., Young J., Harpaz N., Meltzer S.J. A transforming growth factor beta 1 receptor type II mutation in ulcerative colitis-associated neoplasms. Gastroenterol. 112:1997;297-302.
17. Massague J. The transforming growth factor-β family. Annu Rev Cell Biol. 6:1990;597-641.
18. Filmus J., Kerbel R.K. Development of resistance mechanisms to the growth-inhibitory effects of transforming growth factor-β during tumor progression. Opin Oncol. 5:1993;123-129.
19. Geiser A.G., Burmester J.K., Webbink R., Webbink R., Roberts B.A., Sporn B.M. Inhibition of growth by transforming growth factor-β following fusion of two nonresponsive human carcinoma cell lines. J Biol Chem. 267:1992;2588-2593.
20. Sun L., Wu G., Willson J.K., Zborowska E., Yang J., Rajkarunanayake I., Wang J., Gentry L.E., Wang X.F., Brattain M.G. Expression of transforming growth factor β type II receptor leads to reduced malignancy in human breast cancer MCF-7 cells. J Biol Chem. 269:1994;26449-26455.
21. Horii A., Han H.J., Shimada M., Yanagisawa A., Kato Y., Ohta H., Yasui W., Tahara E., Nakamura Y. Frequent replication errors at microsatellite loci in tumors of patients with multiple primary cancers. Cancer Res. 54:1994;3373-3375.
22. Akiyama Y., Nagasaki H., Nihei Z., Iwama T., Nomizu T., Utsunomiya J., Yuasa Y. Frequent microsatellite instabilities and analyses of the related genes in familial gastric cancers. Jpn J Cancer Res. 87:1996;595-601.
23. Renault B., Calistri D., Buonsanti G., Nanni O., Amadori D., Ranzani N.G. Microsatellite instability and mutations of p53 and TGF-β RII genes in gastric cancer. Hum Genet. 98:1996;601-607.
24. Chung Y.J., Park S.W., Song J.M., Lee K.Y., Seo E.J., Choi S.W., Rhyu M.G. Evidence of genetic progression in human gastric carcinomas with microsatellite instability. Oncogene. 15:1997;1719-1726.
25. Wu M.S., Lee C.W., Shun C.T., Wang H.P., Lee W.J., Sheu J.C., Lin J.T. Clinicopathological significance of altered loci of replication error and microsatellite instability-associated mutations in gastric cancer. Cancer Res. 58:1998;1494-1497.