-
1
-
-
50549121134
-
The distribution of secondary growths in cancer of the breast
-
Paget, S. 1889. The distribution of secondary growths in cancer of the breast. Lancet. 1:571-572.
-
(1889)
Lancet
, vol.1
, pp. 571-572
-
-
Paget, S.1
-
2
-
-
0023137823
-
The clinical course of bone metastases from breast cancer
-
Coleman, R.E., and Rubens, R.D. 1987. The clinical course of bone metastases from breast cancer. Br. J. Cancer. 55:61-66.
-
(1987)
Br. J. Cancer
, vol.55
, pp. 61-66
-
-
Coleman, R.E.1
Rubens, R.D.2
-
3
-
-
0023037767
-
Growth factors in bone matrix
-
Hauschka, P.V., Mavrakos, A.E., Iafrati, M.D., Doleman, S.E., and Klagsbrun, M. 1986. Growth factors in bone matrix. J. Biol. Chem. 261:12665-12674.
-
(1986)
J. Biol. Chem.
, vol.261
, pp. 12665-12674
-
-
Hauschka, P.V.1
Mavrakos, A.E.2
Iafrati, M.D.3
Doleman, S.E.4
Klagsbrun, M.5
-
4
-
-
1542792345
-
Modulation of transforming growth factor β activity in bone cultures by osteotrophic hormones
-
Pfeilschifter, J., and Mundy, G.R. 1987. Modulation of transforming growth factor β activity in bone cultures by osteotrophic hormones. Proc. Natl. Acad. Sci. USA. 84:2024-2028.
-
(1987)
Proc. Natl. Acad. Sci. USA
, vol.84
, pp. 2024-2028
-
-
Pfeilschifter, J.1
Mundy, G.R.2
-
5
-
-
0022928247
-
Scanning electron microscopy in bone pathology: Review of methods. Potential and applications
-
Boyde, A., Maconnachie, E., Reid, S.A., Delling, G., and Mundy, G.R. 1986. Scanning electron microscopy in bone pathology: review of methods. Potential and applications. Scanning Electron Microsc. 4:1537-1554.
-
(1986)
Scanning Electron Microsc.
, vol.4
, pp. 1537-1554
-
-
Boyde, A.1
Maconnachie, E.2
Reid, S.A.3
Delling, G.4
Mundy, G.R.5
-
6
-
-
10544228130
-
Efficacy of pamidronate in reducing skeletal complications in patients with breast cancer and lytic bone metastases
-
Hortobagyi, G.N., et al. 1996. Efficacy of pamidronate in reducing skeletal complications in patients with breast cancer and lytic bone metastases. N. Engl. J. Med. 335:1785-1791.
-
(1996)
N. Engl. J. Med.
, vol.335
, pp. 1785-1791
-
-
Hortobagyi, G.N.1
-
7
-
-
0032491037
-
Reduction in new metastases in breast cancer with adjuvant clodronate treatment
-
Diel, I.J., et al. 1998. Reduction in new metastases in breast cancer with adjuvant clodronate treatment. N. Engl. J. Med. 339:357-363.
-
(1998)
N. Engl. J. Med.
, vol.339
, pp. 357-363
-
-
Diel, I.J.1
-
8
-
-
0023259132
-
Identification of a novel 17,000-dalton parathyroid hormone-like adenylate cyclase-stimulating protein from a tumor associated with humoral hypercalcemia of malignancy
-
Burtis, W.J., et al. 1987. Identification of a novel 17,000-dalton parathyroid hormone-like adenylate cyclase-stimulating protein from a tumor associated with humoral hypercalcemia of malignancy. J. Biol. Chem. 262:7151-7156.
-
(1987)
J. Biol. Chem.
, vol.262
, pp. 7151-7156
-
-
Burtis, W.J.1
-
9
-
-
0345338496
-
Parathyroid hormone-related protein purified from a human lung cancer cell line
-
Moseley, J.M., et al. 1987. Parathyroid hormone-related protein purified from a human lung cancer cell line. Proc. Natl. Acad. Sci. USA. 84:5048-5052.
-
(1987)
Proc. Natl. Acad. Sci. USA
, vol.84
, pp. 5048-5052
-
-
Moseley, J.M.1
-
10
-
-
0023472542
-
Parathyroid hormone-like protein from human renal carcinoma cells structural and functional homology with parathyroid hormone
-
Strewler, G.J., et al. 1987. Parathyroid hormone-like protein from human renal carcinoma cells structural and functional homology with parathyroid hormone. J. Clin. Invest. 80:1803-1807.
-
(1987)
J. Clin. Invest.
, vol.80
, pp. 1803-1807
-
-
Strewler, G.J.1
-
11
-
-
0026344131
-
AG protein-linked receptor for parathyroid hormone and parathyroid hormone-related peptide
-
Jüppner, H., et al. 1991. AG protein-linked receptor for parathyroid hormone and parathyroid hormone-related peptide. Science. 254:1024-1026.
-
(1991)
Science
, vol.254
, pp. 1024-1026
-
-
Jüppner, H.1
-
12
-
-
0026598246
-
Expression cloning of a common receptor for parathyroid hormone and parathyroid hormone-related peptide from rat osteoblast-like cells: A single receptor stimulates intracellular accumulation of both cAMP and inositol triphosphates and increases intracellular free calcium
-
Abou-Samra, A., et al. 1992. Expression cloning of a common receptor for parathyroid hormone and parathyroid hormone-related peptide from rat osteoblast-like cells: a single receptor stimulates intracellular accumulation of both cAMP and inositol triphosphates and increases intracellular free calcium. Proc. Natl. Acad. Sci. USA. 89:2732-2736.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 2732-2736
-
-
Abou-Samra, A.1
-
13
-
-
0025318826
-
Immunochemical characterization of circulating parathyroid hormone-related protein in patients with humoral hypercalcemia of cancer
-
Burtis, W.J., et al. 1990. Immunochemical characterization of circulating parathyroid hormone-related protein in patients with humoral hypercalcemia of cancer. N. Engl. J. Med. 322:1106-1112.
-
(1990)
N. Engl. J. Med.
, vol.322
, pp. 1106-1112
-
-
Burtis, W.J.1
-
14
-
-
0025746225
-
Parathyroid hormone related protein and hypercalcaemia in breast cancer
-
Hundred, N.J., et al. 1991. Parathyroid hormone related protein and hypercalcaemia in breast cancer. Br. Med. J. 303:1506-1509.
-
(1991)
Br. Med. J.
, vol.303
, pp. 1506-1509
-
-
Hundred, N.J.1
-
15
-
-
0025821071
-
Localization of parathyroid hormone-related protein in breast cancer metastasis: Increased incidence in bone compared with other sites
-
Powell, G.J., et al. 1991. Localization of parathyroid hormone-related protein in breast cancer metastasis: increased incidence in bone compared with other sites. Cancer Res. 51:3059-3061.
-
(1991)
Cancer Res.
, vol.51
, pp. 3059-3061
-
-
Powell, G.J.1
-
16
-
-
0025674602
-
Immunohistochemical localization of parathyroid hormone-related protein in breast cancer
-
Southby, J., et al. 1990. Immunohistochemical localization of parathyroid hormone-related protein in breast cancer. Cancer Res. 50:7710-7716.
-
(1990)
Cancer Res.
, vol.50
, pp. 7710-7716
-
-
Southby, J.1
-
17
-
-
10144241022
-
Evidence for a causal role of parathyroid hormone-related protein in breast cancer-mediated osteolysis
-
Guise, T.A., et al. 1996. Evidence for a causal role of parathyroid hormone-related protein in breast cancer-mediated osteolysis. J. Clin. Invest. 98:1544-1548.
-
(1996)
J. Clin. Invest.
, vol.98
, pp. 1544-1548
-
-
Guise, T.A.1
-
18
-
-
0011713035
-
Transforming growth factor β increases stability of parathyroid hormone-related protein messenger RNA
-
Zakalik, D., Diep, D., Hooks, M.A., Nissenson, R.A., and Strewler, G.J. 1992. Transforming growth factor β increases stability of parathyroid hormone-related protein messenger RNA. J. Bone Miner. Res. 7:104A, S118.
-
(1992)
J. Bone Miner. Res.
, vol.7
, Issue.104 A
-
-
Zakalik, D.1
Diep, D.2
Hooks, M.A.3
Nissenson, R.A.4
Strewler, G.J.5
-
19
-
-
0027410965
-
Transforming growth factor β stimulation of parathyroid hormone-related protein (PTHrP): A paracrine regulator?
-
Kiriyama, T., et al. 1992. Transforming growth factor β stimulation of parathyroid hormone-related protein (PTHrP): a paracrine regulator? Mol. Cell. Endocrinol. 92:55-62.
-
(1992)
Mol. Cell. Endocrinol.
, vol.92
, pp. 55-62
-
-
Kiriyama, T.1
-
20
-
-
0028355732
-
Effects of transforming growth factor-β on parathyroid hormone-related protein production and ribonucleic acid expression by a squamous carcinoma cell line in vitro
-
Merryman, J.I., DeWille, J.W., Werkmeister, J.R., Capen, C.C., and Rosol, T.J. 1994. Effects of transforming growth factor-β on parathyroid hormone-related protein production and ribonucleic acid expression by a squamous carcinoma cell line in vitro. Endocrinology. 134:2424-2430.
-
(1994)
Endocrinology
, vol.134
, pp. 2424-2430
-
-
Merryman, J.I.1
DeWille, J.W.2
Werkmeister, J.R.3
Capen, C.C.4
Rosol, T.J.5
-
21
-
-
0029916853
-
Cell-specific and regulator-induced promoter usage and messenger ribonucleic acid splicing for parathyroid hormone-related protein
-
Southby, J., Murphy, L.M., Martin, T.J., and Gillespie, M.T. 1996. Cell-specific and regulator-induced promoter usage and messenger ribonucleic acid splicing for parathyroid hormone-related protein. Endocrinology. 137:1349-1357.
-
(1996)
Endocrinology
, vol.137
, pp. 1349-1357
-
-
Southby, J.1
Murphy, L.M.2
Martin, T.J.3
Gillespie, M.T.4
-
22
-
-
0016287342
-
Breast tumor cell lines from pleural effusions
-
Cailleau, R., Yong, R., Olive, M., and Reeves, W.J. 1974. Breast tumor cell lines from pleural effusions. J. Natl. Cancer Inst. 53:661-674.
-
(1974)
J. Natl. Cancer Inst.
, vol.53
, pp. 661-674
-
-
Cailleau, R.1
Yong, R.2
Olive, M.3
Reeves, W.J.4
-
23
-
-
0027367937
-
Signaling activity of transforming growth factor β type II receptors lacking specific domains in the cytoplasmic region
-
Wieser, R., Attisano, L., Wrana, J.L., and J. Massagué, 1993. Signaling activity of transforming growth factor β type II receptors lacking specific domains in the cytoplasmic region. Mol. Cell. Biol. 13:7239-7247.
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 7239-7247
-
-
Wieser, R.1
Attisano, L.2
Wrana, J.L.3
Massagué, J.4
-
24
-
-
0029022221
-
GS domain mutations that constitutively activate T beta R-I, the downstream signaling component in the TGF-beta receptor complex
-
Wieser, R., Wrana, J.L., and Massagué, J. 1995. GS domain mutations that constitutively activate T beta R-I, the downstream signaling component in the TGF-beta receptor complex. EMBO J. 14:2199-2208.
-
(1995)
EMBO J.
, vol.14
, pp. 2199-2208
-
-
Wieser, R.1
Wrana, J.L.2
Massagué, J.3
-
25
-
-
0028359376
-
Type I receptors specify growth-inhibitory and transcriptional responses to transforming growth factor β and activin
-
Cárcamo, J., et al. 1994. Type I receptors specify growth-inhibitory and transcriptional responses to transforming growth factor β and activin. Mol. Cell. Biol. 14:3810-3821.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 3810-3821
-
-
Cárcamo, J.1
-
26
-
-
0026474485
-
Chinese hamster ovarian cells transfected with human parathyroid hormone-related protein cDNA cause hypercalcemia in nude mice
-
Guise, T.A., Chirgwin, J.M., Favarato, G., Boyce, B.F., and Mundy, G.R. 1992. Chinese hamster ovarian cells transfected with human parathyroid hormone-related protein cDNA cause hypercalcemia in nude mice. Lab. Invest. 67:477-485.
-
(1992)
Lab. Invest.
, vol.67
, pp. 477-485
-
-
Guise, T.A.1
Chirgwin, J.M.2
Favarato, G.3
Boyce, B.F.4
Mundy, G.R.5
-
27
-
-
0026530396
-
Modified immunoradiometric assay of parathyroid hormone-related protein: Clinical application in the differential diagnosis of hypercalcemia
-
Pandian, M.R., Morgan, C.H., Carlton, E., and Segre, G.V. 1992. Modified immunoradiometric assay of parathyroid hormone-related protein: clinical application in the differential diagnosis of hypercalcemia. Clin. Chem. 38:282-288.
-
(1992)
Clin. Chem.
, vol.38
, pp. 282-288
-
-
Pandian, M.R.1
Morgan, C.H.2
Carlton, E.3
Segre, G.V.4
-
28
-
-
0031685620
-
TGF-β signal transduction
-
Massagué, J. 1998. TGF-β signal transduction. Annu. Rev. Biochem. 67:753-791.
-
(1998)
Annu. Rev. Biochem.
, vol.67
, pp. 753-791
-
-
Massagué, J.1
-
29
-
-
0029101805
-
The bisphosphonate risedronate reduces metastatic human breast cancer burden in bone in nude mice
-
Sasaki, A., et al. 1995. The bisphosphonate risedronate reduces metastatic human breast cancer burden in bone in nude mice. Cancer Res. 55:3551-3557.
-
(1995)
Cancer Res.
, vol.55
, pp. 3551-3557
-
-
Sasaki, A.1
-
30
-
-
0030032788
-
The multifunctional role of transforming growth factor (TGF)-βs on mammary epithelial cell biology
-
Arteaga, C.L., Dugger, T.C., and Hurd, S.D. 1996. The multifunctional role of transforming growth factor (TGF)-βs on mammary epithelial cell biology. Breast Cancer Res. Treat. 38:49-56.
-
(1996)
Breast Cancer Res. Treat.
, vol.38
, pp. 49-56
-
-
Arteaga, C.L.1
Dugger, T.C.2
Hurd, S.D.3
-
31
-
-
0029010734
-
Mammary tumor suppression by transforming growth factor β1 transgene expression
-
Pierce, D.F., Jr., et al. 1995. Mammary tumor suppression by transforming growth factor β1 transgene expression. Proc. Natl. Acad. Sci. USA. 92:4254-4258.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 4254-4258
-
-
Pierce D.F., Jr.1
-
32
-
-
0028075837
-
Expression of transforming growth factor β type II receptor leads to reduced malignancy in human breast cancer MCF-7 cells
-
Sun, L., et al. 1994. Expression of transforming growth factor β type II receptor leads to reduced malignancy in human breast cancer MCF-7 cells. J. Biol. Chem. 269:26449-26455.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 26449-26455
-
-
Sun, L.1
-
33
-
-
0031441041
-
Transgenic mice overexpressing a dominant-negative mutant type II transforming growth factor β receptor show enhanced tumori-genesis in the mammary gland and lung in response to the carcinogen 7,12-dimethylbenz-[a]-anthracene
-
Böttinger, E.P., Jakubczak, J.L., Haines, D.C., Bagnall, K., and Wakefield, L.M. 1997. Transgenic mice overexpressing a dominant-negative mutant type II transforming growth factor β receptor show enhanced tumori-genesis in the mammary gland and lung in response to the carcinogen 7,12-dimethylbenz-[a]-anthracene. Cancer Res. 57:5564-5569.
-
(1997)
Cancer Res.
, vol.57
, pp. 5564-5569
-
-
Böttinger, E.P.1
Jakubczak, J.L.2
Haines, D.C.3
Bagnall, K.4
Wakefield, L.M.5
-
34
-
-
0029066689
-
Inactivation of the type II TGF-β receptor in colon cancer cells with microsatellite instability
-
Markowitz, S., et al. 1995. Inactivation of the type II TGF-β receptor in colon cancer cells with microsatellite instability. Science. 268:1336-1338.
-
(1995)
Science
, vol.268
, pp. 1336-1338
-
-
Markowitz, S.1
-
35
-
-
16044369574
-
MADR2 maps to 18q12 and encodes a TGFβ-regulated MAD-related protein that is functionally mutated in colorectal carcinoma
-
Eppert, K., et al. 1996. MADR2 maps to 18q12 and encodes a TGFβ-regulated MAD-related protein that is functionally mutated in colorectal carcinoma. Cell. 88:543-552.
-
(1996)
Cell
, vol.88
, pp. 543-552
-
-
Eppert, K.1
-
36
-
-
0032544448
-
Smad3 mutant mice develop metastatic colorectal cancer
-
Zhu, Y., Richardson, J.A., Parada, L.F., and Graff, J.M. 1998. Smad3 mutant mice develop metastatic colorectal cancer. Cell. 94:703-714.
-
(1998)
Cell
, vol.94
, pp. 703-714
-
-
Zhu, Y.1
Richardson, J.A.2
Parada, L.F.3
Graff, J.M.4
-
37
-
-
0030593038
-
DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1
-
Hahn, S.A., et al. 1996. DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1. Science. 271:259-253.
-
(1996)
Science
, vol.271
, pp. 259-1253
-
-
Hahn, S.A.1
-
38
-
-
0032489508
-
Intestinal tumorigenesis in compound mutant mice of both Dpc4 (Smad4) and Ape genes
-
Takaku, K., et al. 1998. Intestinal tumorigenesis in compound mutant mice of both Dpc4 (Smad4) and Ape genes. Cell. 92:645-656.
-
(1998)
Cell
, vol.92
, pp. 645-656
-
-
Takaku, K.1
-
39
-
-
0030598681
-
TGFβ1 inhibits the formation of benign skin tumors, but enhances progression to invasive spindle carcinomas in transgenic mice
-
Cui, W.E., et al. 1996. TGFβ1 inhibits the formation of benign skin tumors, but enhances progression to invasive spindle carcinomas in transgenic mice. Cell. 86:531-542.
-
(1996)
Cell
, vol.86
, pp. 531-542
-
-
Cui, W.E.1
-
40
-
-
0029101527
-
Chronic exposure of cultured transfected mouse epidermal cells to TGFβ1 induces an epithelial-mesenchymal transdifferentiation and a spindle tumoral phenotype
-
Caulin, C., Scholl, S.G., Frontelo, P., Gamallo, C., and Quintanilla, M. 1995. Chronic exposure of cultured transfected mouse epidermal cells to TGFβ1 induces an epithelial-mesenchymal transdifferentiation and a spindle tumoral phenotype. Cell Growth Differ. 6:1027-1035.
-
(1995)
Cell Growth Differ
, vol.6
, pp. 1027-1035
-
-
Caulin, C.1
Scholl, S.G.2
Frontelo, P.3
Gamallo, C.4
Quintanilla, M.5
-
41
-
-
0028603343
-
TGF-β induced transdifferentiation of mammary epithelial cells to mesenchymal cells: Involvement of type I receptors
-
Miettinen, P.J., Ebner, R., Lopez, A.R., and Derynck, R. 1994. TGF-β induced transdifferentiation of mammary epithelial cells to mesenchymal cells: involvement of type I receptors. J. Cell Biol. 127:2021-2036.
-
(1994)
J. Cell Biol.
, vol.127
, pp. 2021-2036
-
-
Miettinen, P.J.1
Ebner, R.2
Lopez, A.R.3
Derynck, R.4
-
42
-
-
0029662049
-
TGF-β1 and Ha-Ras collaborate in modulating the phenotypic plasticity and invasiveness of epithelial tumor cells
-
Oft, M., et al. 1996. TGF-β1 and Ha-Ras collaborate in modulating the phenotypic plasticity and invasiveness of epithelial tumor cells. Genes Dev. 10:2462-2477.
-
(1996)
Genes Dev.
, vol.10
, pp. 2462-2477
-
-
Oft, M.1
-
43
-
-
0030773834
-
Opposing BMP and EGF signalling pathways converge on the TGF-β family mediator Smad1
-
Kretzschmar, M., Doody, J., and Massagué, J. 1997. Opposing BMP and EGF signalling pathways converge on the TGF-β family mediator Smad1. Nature. 389:618-622.
-
(1997)
Nature
, vol.389
, pp. 618-622
-
-
Kretzschmar, M.1
Doody, J.2
Massagué, J.3
-
44
-
-
0028835253
-
A peptidomimetic inhibitor of farnesyl:protein transferase blocks the anchorage-dependent and -independent growth of human tumor cell lines
-
Sepp-Lorenzino, L., et al. 1995. A peptidomimetic inhibitor of farnesyl:protein transferase blocks the anchorage-dependent and -independent growth of human tumor cell lines. Cancer Res. 55:5302-5309.
-
(1995)
Cancer Res.
, vol.55
, pp. 5302-5309
-
-
Sepp-Lorenzino, L.1
-
45
-
-
0342460497
-
Expression of a dominant-negative mutant TGF-β type II receptor in transgenic mice reveals essential roles for TGF-β in regulation of growth and differentiation in the exocrine pancreas
-
Böttinger, E.P., et al. 1997. Expression of a dominant-negative mutant TGF-β type II receptor in transgenic mice reveals essential roles for TGF-β in regulation of growth and differentiation in the exocrine pancreas. EMBO J. 16:2621-2633.
-
(1997)
EMBO J.
, vol.16
, pp. 2621-2633
-
-
Böttinger, E.P.1
|