Presence of multiple incontiguous deleted regions at the long arm of chromosome 18 in head and neck cancer

Clinical Cancer Research

Volumn 4, Issue 3, 1998, Pages 539-544

  Papadimitrakopoulou, Vali A ^a   Oh, Yun ^a   El Naggar, Adel ^a   Izzo, Julie ^a   Clayman, Gary ^a   Mao, Li ^a  

^a UNIVERSITY OF TEXAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CARCINOGENESIS; CHROMOSOME 18Q; CONTROLLED STUDY; GENE DELETION; HEAD AND NECK CANCER; HUMAN; HUMAN CELL; HUMAN TISSUE; PRIORITY JOURNAL; TUMOR SUPPRESSOR GENE;

EID: 0031946721     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (37)

1. Cavenee, W. K., and White, R. L. The genetic basis of cancer. Sci. Am., 272; 72-79, 1995.
2. Knudson, A. G. Antioncogenes and human cancer. Proc. Natl. Acad. Sci. USA, 90: 10914-10921, 1993.
3. Califano, J., van der Riet, P., Westra, W., Nawroz, H., Clayman, G., Piantadosi, S., Corio, R., Lee, D., Greenberg, B., Koch, W., and Sidransky, D. Genetic progression model for head and neck cancer: implications for field cancerization. Cancer Res., 56: 2488-2492, 1996.
4. Ah-See, K. W., Cooke, T. G., Pickford, I. R., Soutar, D., and Balmain, A. An allelotype of squamous carcinoma of the head and neck using microsatellite markers. Cancer Res., 54: 1617-1621, 1994.
5. Nawroz, H., van der Riet, P., Hruban, R. H., Koch, W., Ruppert, J. M., and Sidransky, D. Allelotype of head and neck squamous cell carcinoma. Cancer Res., 54: 1152-1155, 1994.
6. Worsham, M. J., Van Dyke, D. L., Grenman, S. E., Grenman, R., Hopkins, M. P., Roberts, J. A., Gasser, K. M., Schwanz, D. R., and Carey, T. E. Consistent chromosome abnormalities in squamous cell carcinoma of the vulva. Genes Chromosomes Cancer, 3: 420-432, 1991.
7. Carey, T. E., Worsham, M. J., and Van Dyke, D. L. Nonrandom chromosome aberrations and clonal populations in head and neck cancers. Anticancer Res., 13: 2561-2568, 1993.
8. Van Dyke, D. L., Worsham, M. J., Benninger, M. S., Krause, C. J., Baker, S. R., Wolf, G. T., Drumhekker, T., Tilley, B. C., and Carey, T. Recurrent cytogenetic abnormalities in squamous cell carcinomas of the head and neck region. Genes Chromosomes Cancer, 9: 192-206, 1994.
9. Rowley, H., Jones, A. S., and Field, J. K. Chromosome 18: a possible site for a tumor suppressor gene deletion in squamous cell carcinoma of the head and neck. Clin. Otolaryngol. (Oxf.), 20: 266-271, 1995.
10. Kelker, W., Van Dyke, D. L., Worsham, M. J., Christopherson, P. L., James, C. D., Conlon, M. R., and Carey, T. E. Loss of 18q and homozygosity for the DCC locus: possible markers for clinically aggressive squamous cell carcinoma. Anticancer Res., 16: 2365-2372, 1996.
11. Jen, J., Kim, H., Piantadosi, S., Liu, Z-F., Levitt, R. C., Sistonen, P., Kinzler, K. W., Vogelstein, B., and Hamilton, S. R. Allelic loss of chromosome 18q and prognosis in colorectal cancer. N. Engl. J. Med., 331: 213-221, 1994.
12. Kim, S. K., Fan, Y., Papadimitrakopoulou, V., Clayman, G., Hittelman, W. N., and Hong, W. K. DPC4, a candidate tumor suppressor gene, is altered infrequently in head and neck squamous cell carcinoma. Cancer Res., 56: 2519-2521, 1996.
13. Massagué, J., Hata, A., and Liu, F. TGF-β signaling through the Smad pathway. Trends Cell Biol., 7: 187-192, 1997.
14. Eppert, K., Scherer, S. W., Ozcelic, H., Pirone, R., Hoodless, P., Kim, H., Tsui, L-C., Babat, B., Gallinger, S., Andrulis, I. L., Thomsen, G. H., Wrana, J. L., and Attisano, L. MADR2 maps to 18q21 and encodes a TGFβ-regulated MAD-related protein that is functionally mutated in colorectal carcinoma. Cell, 86: 543-552, 1996.
15. Carey, T. E. Establishment of epidermoid carcinoma cell lines. In: R. E. Wittes (ed.), Head and Neck Cancer, pp. 287-314. New York: John Wiley & Sons, 1985.
16. Mao, L., Lee, J. S., Fan, Y. H., Ro, J. Y., Batsakis, J. G., Lippman, S. M., Hittelman. W. N., and Hong, W. K. Frequent microsatellite alterations at chromosomes 9p21 and 3p14 in oral premalignant lesions and their value in cancer risk assessment. Nat. Med., 2: 682-685, 1996.
17. Giacalone, J., Li, X., Lehrach, H., and Francke, U. High density radiation hybrid map of human chromosome 18 and contig of 18p. Genomics, 37: 9-18, 1996.
18. Dib, C., Faure, S., Fizames, C., Samson, D., Drouot, N., Vignal, A., Millasseau, P., Marc, S., Hazan, J., Seboun, E., Lathrop, M., Gyapay, G., Morissette, J., and Weissenbach, J. A comprehensive genetic map of the human genome based on 5,264 microsatellites. Nature (Lond.), 380: 152-154, 1996.
19. Cairns, P., Polascik, T. J., Eby, Y., Tokino, K., Califano, J., Merlo, A., Mao, L., Herath, J., Jenkins, R., Westra, W., Rutter, J. L., Buckler, A., Gabrielson, E., Tockman, M., Cho, K. R., Hedrick, L., Bova, G. S., Isaacs, W., Koch, W., Schwab, D., and Sidransky, D. Frequency of homozygous deletion at p16/CDKN2 in primary tumours. Nat. Genet., 11: 210-212, 1995.
20. Thiagalingam, S., Lengauer, C., Leac, F. S., Schutte, M., Hahn, S. A., Overhauser, J., Willson, J. K. V., Markowitz, S., Hamilton, S. R., Kern, S. E., Kinzler, K. W., and Vogelstein, B. Evaluation of candidate tumour suppressor genes on chromosome 18 in colorectal cancers. Nat. Genet., 13: 343-346, 1996.
21. Frank, C. J., McClatchey, K. D., Devaney, K. O., and Carey, T. E. Evidence that loss of 18q is associated with tumor progression. Cancer Res., 57: 824-827, 1997.
22. Jones, J. W., Raval, J. R., Beals, T. F., Worsham, M. J., Van Dyke, D. L., Esclamado, R. M., Wolf, G. T., Bradford, C. R., Miller, T., and Carey, T. E. Frequent loss of heterozygosity on chromosome arm 18q in squamous cell carcinomas. Arch. Otolaryngol. Head Neck Surg., 123: 610-614, 1997.
23. Francke, U., Chang, E., Comeau, K., Geigl, E. M., Giacalone, J., Li, X., Luna, J., Moon, S., Welch, S., and Wilgenbus, P. A radiation hybrid map of chromosome 18. Cytogenet. Cell Genet., 66: 196-213, 1994.
24. Le Beau, M. M., Overhauser, J., Strub, R. E., Silverman, G., Gilliam, T. C., Ott, J., O'Connell, P., Francke, U., and van Kessel, A. G. Report of the first international workshop on human chromosome 18 mapping. Cytogenet. Cell Genet., 63: 78-96, 1993.
25. Croce, C. M. Genetic approaches to the study of the molecular basis of cancer. Cancer Res., 51: 5015s-5018s, 1991.
26. Fearon, E., Cho, K. R., Nigro, J. M., Kern, S. E., Simons, J. W., Ruppert, J. M., Hamilton, S. R., Preisinger, A. C., Thomas, G., Kinzler, K. W., and Vogelstein, B. Identification of a chromosome 18q gene that is altered in colorectal cancers. Science (Washington DC), 247: 49-56, 1990.
27. Hahn, S. A., Schutte, M., Shamsul Hoque, A. T. M., Moskaluk, C. A., da Costa, L. T., Rozenblum, E., Weinstern, C. L., Fischer, A., Yea, C. J., Hruban, R. H., and Kern, S. E. DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1. Science (Washington DC), 271: 350-353, 1996.
28. Derynck, R., and Zhang, Y. Intracellular signaling: the Mad way to do it. Curr. Biol., 6: 1226-1229, 1996.
29. Massagué, J. TGFβ signalling: receptors, transducers, and MAD proteins. Cell, 85: 947-950, 1996.
30. Riggins, G. J., Thiagalingam, S., Rozenblum, E., Weinstein, C. L., Kern, S. E., Hamilton, S. R., Willson, J. V., Markowitz, S. D., Kinzler, K. W., and Vogelstein B. Mad-related genes in the human. Nat. Genet., 13: 347-349, 1996.
31. Markowitz, S. D., and Roberts, A. B. Tumor suppressor activity of the TGFβ pathway in human cancers. Cytokine Growth Factor Rev., 7: 93-102, 1996.
32. Reiss, M., and Stash, E. B. High frequency of resistance of human squamous cells to the anti-proliferative action of transforming growth factor-β. Cancer Commun., 2: 363-369, 1990.
33. Garrigue-Antar, L., Muñoz-Antonia, T., Antonia, S. J., Gesmonde, J., Vellucci, V. F., and Reiss, M. Missense mutations of the transforming growth factor β type II receptor in human head and neck squamous carcinoma cells. Cancer Res., 55: A3982-3987, 1995.
34. Wang, D., Song, H., Lang, J. C., Schuller, D. E., and Weghorst, C. M. Alteration of the transforming growth factor β type II receptor gene in squamous cell carcinoma of the head and neck. Proc. Am. Assoc. Cancer Res., 38: A3800, 1997.
35. Uchida, K., Nagatake, M., Osada, H., Yatabe, Y., Kondo, M., Mitsudomi, T., Masuda, A., Takahashi, T., and Takahashi, T. Somatic in vivo alterations of the JV18-1 gene at 18q21 in human lung cancers. Cancer Res., 56: 5583-5585, 1996.
36. Klingelhultz, A. J., Smith, P. P., Garrett, L. R., and McDougall, J. K. Alteration of the DCC tumor-suppressor gene in tumorigenic HPV-18 immortalized human keratinocytes transformed by nitrosomethylurea. Oncogene, 8: 95-99, 1993.
37. Klingelhultz, A. J., Hedrick, L., Cho, K. R., and McDougall, J. K. The DCC gene suppresses the malignant phenotype of transformed human epithelial cells. Oncogene, 10: 5181-1586, 1995.