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Volumn 283, Issue 5410, 1999, Pages 2080-2082

Requirement of type III TGF-β receptor for endocardial cell transformation in the heart

Author keywords

[No Author keywords available]

Indexed keywords

TRANSFORMING GROWTH FACTOR BETA RECEPTOR;

EID: 0033605704     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.283.5410.2080     Document Type: Article
Times cited : (342)

References (36)
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    • 125I-TGF-β1 (NEN-DuPont) as described previously (17) after incubation with PI or I antisera (5 to 60 μg/ml). Specific binding was determined by the addition of 500 pM TGF-β1 or TGF-β2. Equal volumes of cell lysates were added per gel lane for cross-linking experiments or per sample for immunoprecipitation studies. For cross-linking experiments, the resultant banding patterns were examined by autoradiography and quantified by Phosphorimage analysis. Preimmune antisera had no effect on ligand binding.
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    • note
    • We thank R. Emeson, A. George, L. Limbird, B. Hogan, C. Wright, and members of the Barnett laboratory for critical reading of the manuscript, M. Cleggett for technical assistance, C. Cepko for RCASBP containing alkaline phosphatase, and H. Moses for thoughtful discussion. Supported by grants HL52922 (J.V.B.), 38649 (R.B.R.), 42266 (R.B.R.), and FY98-0446 from the March of Dimes Birth Defects Foundation (J.V.B.), C.B.B. was supported by an institutional training grant from the NIH General Medical Sciences number GM07628. J.V.B. and R.B.R. are Established Investigators of the American Heart Association. J.V.B. wishes to acknowledge the support of the Vanderbilt Cancer Center, NCI CA68485.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.