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Volumn 86, Issue 4, 1996, Pages 531-542

TGFβ1 inhibits the formation of benign skin tumors, but enhances progression to invasive spindle carcinomas in transgenic mice

Author keywords

[No Author keywords available]

Indexed keywords

TRANSFORMING GROWTH FACTOR BETA1; INTEGRIN; KERATIN; TRANSFORMING GROWTH FACTOR BETA;

EID: 0030598681     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(00)80127-0     Document Type: Article
Times cited : (555)

References (93)
  • 1
    • 0023874730 scopus 로고
    • Localized production of TGF-β mRNA in tumour promoter-stimulated mouse epidermis
    • Akhurst, R.J., Fee, F., and Balmain, A. (1988). Localized production of TGF-β mRNA in tumour promoter-stimulated mouse epidermis. Nature 331, 363-365.
    • (1988) Nature , vol.331 , pp. 363-365
    • Akhurst, R.J.1    Fee, F.2    Balmain, A.3
  • 2
    • 0025270339 scopus 로고
    • TGF β in murine morphogenetic processes: The early embryo and cardiogenesis
    • Akhurst, R.J., Lehnert, S.A., Faissner, A.J., and Duffie, E. (1990). TGF β in murine morphogenetic processes: the early embryo and cardiogenesis. Development 108, 645-656.
    • (1990) Development , vol.108 , pp. 645-656
    • Akhurst, R.J.1    Lehnert, S.A.2    Faissner, A.J.3    Duffie, E.4
  • 3
    • 0028953810 scopus 로고
    • Transforming growth factor β and cell cycle regulation
    • Alexandrow, M.G., and Moses, H.L (1995). Transforming growth factor β and cell cycle regulation. Cancer Res. 55, 1452-1457.
    • (1995) Cancer Res. , vol.55 , pp. 1452-1457
    • Alexandrow, M.G.1    Moses, H.L.2
  • 4
    • 0027191429 scopus 로고
    • In situ end-labeling detects DNA strand breaks in apoptosis and other physiological and pathological states
    • Ansari, B., Coates, P.J., Greenstein, B.D., and Hall, P.A. (1993). In situ end-labeling detects DNA strand breaks in apoptosis and other physiological and pathological states. J. Pathol. 170, 1-8.
    • (1993) J. Pathol. , vol.170 , pp. 1-8
    • Ansari, B.1    Coates, P.J.2    Greenstein, B.D.3    Hall, P.A.4
  • 5
    • 0020465034 scopus 로고
    • Synergistic interaction of two classes of transforming growth factors from murine sarcoma cells
    • Anzano, M.A., Roberts, A.B., Meyers, C.A., Komoriya, A., Lamb, L.C., Smith, J.M., and Sporn, M.B. (1982). Synergistic interaction of two classes of transforming growth factors from murine sarcoma cells. Cancer Res. 42, 4776-4778.
    • (1982) Cancer Res. , vol.42 , pp. 4776-4778
    • Anzano, M.A.1    Roberts, A.B.2    Meyers, C.A.3    Komoriya, A.4    Lamb, L.C.5    Smith, J.M.6    Sporn, M.B.7
  • 6
    • 0026656525 scopus 로고
    • Altered metabolic and adhesive properties and increased tumorigenesis associated with increased expression of transforming growth factor β1
    • Arrick, B.A., Lopez, A.R., Elfman, F., Ebner, R., Damsky, C.H., and Derynck, R. (1992). Altered metabolic and adhesive properties and increased tumorigenesis associated with increased expression of transforming growth factor β1. J. Cell Biol. 118, 715-726.
    • (1992) J. Cell Biol. , vol.118 , pp. 715-726
    • Arrick, B.A.1    Lopez, A.R.2    Elfman, F.3    Ebner, R.4    Damsky, C.H.5    Derynck, R.6
  • 7
    • 0025477164 scopus 로고
    • Growth stimulation of human breast cancer cells with anti-transforming growth factor β antibodies: Evidence for negative autocrine regulation by transforming growth factor β
    • Arteaga, C.L., Coffey, R.J., Jr., Dugger, T.C., McCutchen, C.M., Moses, H.L., and Lyons, R.M. (1990). Growth stimulation of human breast cancer cells with anti-transforming growth factor β antibodies: evidence for negative autocrine regulation by transforming growth factor β. Cell Growth Differ. 1, 367-374.
    • (1990) Cell Growth Differ. , vol.1 , pp. 367-374
    • Arteaga, C.L.1    Coffey R.J., Jr.2    Dugger, T.C.3    McCutchen, C.M.4    Moses, H.L.5    Lyons, R.M.6
  • 8
    • 0027569092 scopus 로고
    • Transforming growth factor β1 can induce estrogen-independent tumorgenicity of human breast cancer cells in athymic mice
    • Arteaga, C.L., Carty-Dugger, T., Moses, H.L., Hurd, S.D., and Pietenpol, J.A. (1993a). Transforming growth factor β1 can induce estrogen-independent tumorgenicity of human breast cancer cells in athymic mice. Cell Growth Differ. 4, 193-201.
    • (1993) Cell Growth Differ. , vol.4 , pp. 193-201
    • Arteaga, C.L.1    Carty-Dugger, T.2    Moses, H.L.3    Hurd, S.D.4    Pietenpol, J.A.5
  • 9
    • 0027137485 scopus 로고
    • Anti-transforming growth factor (TGF)-β antibodies inhibit breast cancer cell tumorigenicity and increase mouse spleen natural killer activity
    • Arteaga, C., Hurd, S.D., Winnier, A.R., Johnson, M.D., Fendly, B.M., and Forbes, J.T. (1993b). Anti-transforming growth factor (TGF)-β antibodies inhibit breast cancer cell tumorigenicity and increase mouse spleen natural killer activity. J. Clin. Invest. 92, 2569-2576.
    • (1993) J. Clin. Invest. , vol.92 , pp. 2569-2576
    • Arteaga, C.1    Hurd, S.D.2    Winnier, A.R.3    Johnson, M.D.4    Fendly, B.M.5    Forbes, J.T.6
  • 10
    • 0017178366 scopus 로고
    • Spindle cell carcinoma: Ultrastructural evidence of squamous origin and collagen production by tumour cells
    • Battifora, H.B. (1976). Spindle cell carcinoma: ultrastructural evidence of squamous origin and collagen production by tumour cells. Cancer 37, 2275-2282.
    • (1976) Cancer , vol.37 , pp. 2275-2282
    • Battifora, H.B.1
  • 11
    • 0001460034 scopus 로고
    • Carcinosarcoma of the lung: Review of the literature and report of two cases treated by pneumonectomy
    • Bergmann, M., Ackerman, L.V., and Kemler, R.L. (1951). Carcinosarcoma of the lung: review of the literature and report of two cases treated by pneumonectomy. Cancer 4, 919-929.
    • (1951) Cancer , vol.4 , pp. 919-929
    • Bergmann, M.1    Ackerman, L.V.2    Kemler, R.L.3
  • 12
    • 0026385870 scopus 로고
    • Progression of squamous carcinoma cells to spindle carcinoma of the mouse skin is associated with an imbalance of H-ras alleles on chromosome 7
    • Buchmann, A., Ruggeri, B., Klein-Szanto, A.J.P., and Balmain, A. (1991). Progression of squamous carcinoma cells to spindle carcinoma of the mouse skin is associated with an imbalance of H-ras alleles on chromosome 7. Cancer Res. 51, 4097-4101.
    • (1991) Cancer Res. , vol.51 , pp. 4097-4101
    • Buchmann, A.1    Ruggeri, B.2    Klein-Szanto, A.J.P.3    Balmain, A.4
  • 13
    • 0026599985 scopus 로고
    • Cell death by apoptosis and its protective role against disease
    • Bursch, W., Oberhammer, F., and Schulte-Hermann, R. (1992). Cell death by apoptosis and its protective role against disease. Trends Pharmacol. Sci. 13, 245-251.
    • (1992) Trends Pharmacol. Sci. , vol.13 , pp. 245-251
    • Bursch, W.1    Oberhammer, F.2    Schulte-Hermann, R.3
  • 15
    • 0030034510 scopus 로고    scopus 로고
    • The expression of the cell adhesion molecules E-cadherin, P-cadherin and α6β4 integrin is altered in premalignant skin tumours of p53-deficient mice
    • Cano, A., Gamalla, C., Kemp, C.J., Benito, N., Palacios, J., Quintanilla, M., and Balmain, A. (1996). The expression of the cell adhesion molecules E-cadherin, P-cadherin and α6β4 integrin is altered in premalignant skin tumours of p53-deficient mice. Int. J. Cancer 65, 254-262.
    • (1996) Int. J. Cancer , vol.65 , pp. 254-262
    • Cano, A.1    Gamalla, C.2    Kemp, C.J.3    Benito, N.4    Palacios, J.5    Quintanilla, M.6    Balmain, A.7
  • 16
    • 0029101527 scopus 로고
    • Chronic exposure of cultured transfected mouse epidermal cells to TGFβ1 induces an epithelial-mesenchymal transdifferentiation and a spindle tumoral phenotype
    • Caulin, C., Scholl, S.G., Frontelo, P., Gamallo, C., and Quintanilla, M. (1995). Chronic exposure of cultured transfected mouse epidermal cells to TGFβ1 induces an epithelial-mesenchymal transdifferentiation and a spindle tumoral phenotype. Cell Growth Differ. 6, 1027-1035.
    • (1995) Cell Growth Differ. , vol.6 , pp. 1027-1035
    • Caulin, C.1    Scholl, S.G.2    Frontelo, P.3    Gamallo, C.4    Quintanilla, M.5
  • 17
    • 0026606959 scopus 로고
    • Regulation of human colon-carcinoma cell adhesion to extracellular matrix by transforming growth factor β1
    • Chakrabarty, S. (1992). Regulation of human colon-carcinoma cell adhesion to extracellular matrix by transforming growth factor β1. Int. J. Cancer 50, 968-973.
    • (1992) Int. J. Cancer , vol.50 , pp. 968-973
    • Chakrabarty, S.1
  • 18
    • 0027848683 scopus 로고
    • Increased transforming growth factor β expression inhibits cell proliferation in vitro yet increases tumorigenicity and tumor growth of Meth A sarcoma cells
    • Chang, H.L., Gillett, N., Figaro, I., Lopez, A.R., Palladino, M.A., and Derynck, R. (1993). Increased transforming growth factor β expression inhibits cell proliferation in vitro yet increases tumorigenicity and tumor growth of Meth A sarcoma cells. Cancer Res. 53, 4391-4398.
    • (1993) Cancer Res. , vol.53 , pp. 4391-4398
    • Chang, H.L.1    Gillett, N.2    Figaro, I.3    Lopez, A.R.4    Palladino, M.A.5    Derynck, R.6
  • 19
    • 0027250810 scopus 로고
    • Inactivation of the type II receptor reveals two receptor pathways for the diverse TGF-β activities
    • Chen, R.-H, Ebner, R., and Derynck, R. (1993). Inactivation of the type II receptor reveals two receptor pathways for the diverse TGF-β activities. Science 260, 1335-1338.
    • (1993) Science , vol.260 , pp. 1335-1338
    • Chen, R.-H.1    Ebner, R.2    Derynck, R.3
  • 20
    • 0027585508 scopus 로고
    • Epidermal growth factor receptor ligands regulate keratin 8 expression in keratinocytes, and transforming growth factor α mediates the induction of keratin 8 by the v-ras-Ha oncogene
    • Cheng, C., Tennenbaum, T., Dempsey, P.J., Coffey, R.J., Yuspa, S.H., and Dlugosz, A.A. (1993). Epidermal growth factor receptor ligands regulate keratin 8 expression in keratinocytes, and transforming growth factor α mediates the induction of keratin 8 by the v-ras-Ha oncogene. Cell Growth Differ. 4, 317-327.
    • (1993) Cell Growth Differ. , vol.4 , pp. 317-327
    • Cheng, C.1    Tennenbaum, T.2    Dempsey, P.J.3    Coffey, R.J.4    Yuspa, S.H.5    Dlugosz, A.A.6
  • 21
    • 77957048521 scopus 로고    scopus 로고
    • Transforming growth factors β: Biochemistry and biology in vitro and in vivo
    • C. Bondy and D. LeRoith, eds. (Greenwich, Connecticut: JAI Press), in press
    • Cui, W., and Akhurst, R.J. (1996). Transforming growth factors β: biochemistry and biology in vitro and in vivo. In Growth Factors and Cytokines in Health and Disease, C. Bondy and D. LeRoith, eds. (Greenwich, Connecticut: JAI Press), in press.
    • (1996) Growth Factors and Cytokines in Health and Disease
    • Cui, W.1    Akhurst, R.J.2
  • 22
    • 0028051817 scopus 로고
    • Lack of TGFβ1 expression in benign skin tumours of p53 null mice is prognostic for a high risk of malignant conversion
    • Cui, W., Kemp, C.J., Duffie, E., Balmain, A., and Akhurst, R.J. (1994). Lack of TGFβ1 expression in benign skin tumours of p53 null mice is prognostic for a high risk of malignant conversion. Cancer Res. 54, 5831-5836.
    • (1994) Cancer Res. , vol.54 , pp. 5831-5836
    • Cui, W.1    Kemp, C.J.2    Duffie, E.3    Balmain, A.4    Akhurst, R.J.5
  • 23
    • 0028986244 scopus 로고
    • Concerted action of TGFβ1 and its type II receptor in control of epidermal homeostasis in transgenic mice
    • Cui, W., Fowlis, D.J., Cousins, F.M., Duffie, E., Bryson, S., Balmain, A., and Akhurst, R.J. (1995). Concerted action of TGFβ1 and its type II receptor in control of epidermal homeostasis in transgenic mice. Genes Dev. 9, 945-955.
    • (1995) Genes Dev. , vol.9 , pp. 945-955
    • Cui, W.1    Fowlis, D.J.2    Cousins, F.M.3    Duffie, E.4    Bryson, S.5    Balmain, A.6    Akhurst, R.J.7
  • 24
    • 0023100052 scopus 로고
    • Synthesis of messenger RNAs for transforming growth factors α and β and the epidermal growth factor receptor by human tumors
    • Derynck, R., Goeddel, D.V., Ullrich, A., Gutterman, J.U., Williams, R.D., Bringman, T.S., and Berger, W.H. (1987). Synthesis of messenger RNAs for transforming growth factors α and β and the epidermal growth factor receptor by human tumors. Cancer Res. 47, 707-712.
    • (1987) Cancer Res. , vol.47 , pp. 707-712
    • Derynck, R.1    Goeddel, D.V.2    Ullrich, A.3    Gutterman, J.U.4    Williams, R.D.5    Bringman, T.S.6    Berger, W.H.7
  • 26
    • 0025807097 scopus 로고
    • Immunolocalisation of epidermal growth factor (EGF), EGF receptor and transforming growth factor α (TGFα) during mouse palatogenesis in vitro and in vivo
    • Dixon, M.J., Garner, J., and Ferguson, M.W. (1991). Immunolocalisation of epidermal growth factor (EGF), EGF receptor and transforming growth factor α (TGFα) during mouse palatogenesis in vitro and in vivo. Anat. Embryol. 184, 83-91.
    • (1991) Anat. Embryol. , vol.184 , pp. 83-91
    • Dixon, M.J.1    Garner, J.2    Ferguson, M.W.3
  • 27
    • 0028962318 scopus 로고
    • Autocrine transforming growth factor α is dispensible for v-ras-Ha-induced epidermal neoplasia: Potential involvement of alternative EGF receptor ligands
    • Dlugosz, A.A., Cheng, C., William, E.K., Darwiche, N., Dempsey, P.J., Mann, B., Dunn, A.R., Coffey, R.J., and Yuspa, S.H. (1995). Autocrine transforming growth factor α is dispensible for v-ras-Ha-induced epidermal neoplasia: potential involvement of alternative EGF receptor ligands. Cancer Res. 55, 1883-1893.
    • (1995) Cancer Res. , vol.55 , pp. 1883-1893
    • Dlugosz, A.A.1    Cheng, C.2    William, E.K.3    Darwiche, N.4    Dempsey, P.J.5    Mann, B.6    Dunn, A.R.7    Coffey, R.J.8    Yuspa, S.H.9
  • 28
    • 0018828154 scopus 로고
    • Spindle cell squamous carcinoma and carcinoma-like tumours of the skin: A comparative study of 38 cases
    • Evans, H.L., and Smith, J.L. (1980). Spindle cell squamous carcinoma and carcinoma-like tumours of the skin: a comparative study of 38 cases. Cancer 45, 2687-2697.
    • (1980) Cancer , vol.45 , pp. 2687-2697
    • Evans, H.L.1    Smith, J.L.2
  • 29
    • 0028178732 scopus 로고
    • Expression of β1, β3, β4 and β5 integrins by human lung carcinoma cells of different histotypes
    • Falcioni, R., Cimino, L., Gentileschi, M.P., D'Agnano, I., Zupi, G., Kennel, S.J., and Sacchi, A. (1994). Expression of β1, β3, β4 and β5 integrins by human lung carcinoma cells of different histotypes. Exp. Cell Res. 210, 113-122.
    • (1994) Exp. Cell Res. , vol.210 , pp. 113-122
    • Falcioni, R.1    Cimino, L.2    Gentileschi, M.P.3    D'Agnano, I.4    Zupi, G.5    Kennel, S.J.6    Sacchi, A.7
  • 30
    • 0025287681 scopus 로고
    • Differential expression of TGF β isoforms in murine palatogenesis
    • Fitzpatrick, D.R., Denhez, F., Kondaiah, P., and Akhurst, R.J. (1990). Differential expression of TGF β isoforms in murine palatogenesis. Development 109, 585-595.
    • (1990) Development , vol.109 , pp. 585-595
    • Fitzpatrick, D.R.1    Denhez, F.2    Kondaiah, P.3    Akhurst, R.J.4
  • 32
    • 0026811858 scopus 로고
    • Discordant TGFβ1 RNA and protein localisations during chemical carcinogenesis of the skin
    • Fowlis, D.J., Flanders, K., Duffie, E., Balmain, A., and Akhurst, R.J. (1992). Discordant TGFβ1 RNA and protein localisations during chemical carcinogenesis of the skin. Cell Growth Differ. 3, 81-91.
    • (1992) Cell Growth Differ. , vol.3 , pp. 81-91
    • Fowlis, D.J.1    Flanders, K.2    Duffie, E.3    Balmain, A.4    Akhurst, R.J.5
  • 33
    • 0029802491 scopus 로고    scopus 로고
    • Altered epidermal growth control in vivo in transgenic mice expressing TGFβ1 from an inducible keratin gene promoter
    • Fowlis, D.J., Cui, W., Johnson, S.A., Balmain, A., and Akhurst, R.J. (1996). Altered epidermal growth control in vivo in transgenic mice expressing TGFβ1 from an inducible keratin gene promoter. Cell Growth Differ. 7, 679-687.
    • (1996) Cell Growth Differ. , vol.7 , pp. 679-687
    • Fowlis, D.J.1    Cui, W.2    Johnson, S.A.3    Balmain, A.4    Akhurst, R.J.5
  • 34
    • 0024334332 scopus 로고
    • Stimulatory role of transforming growth factors in multistage skin carcinogenesis: Possible explanation for the tumor-inducing effect of wounding in initiated NMRI mouse skin
    • Furstenberger, G., Rogers, M., Schnapke, R., Bauer, G., Hofler, P., and Marks, F. (1989). Stimulatory role of transforming growth factors in multistage skin carcinogenesis: possible explanation for the tumor-inducing effect of wounding in initiated NMRI mouse skin. Int J. Cancer 43, 915-921.
    • (1989) Int J. Cancer , vol.43 , pp. 915-921
    • Furstenberger, G.1    Rogers, M.2    Schnapke, R.3    Bauer, G.4    Hofler, P.5    Marks, F.6
  • 35
    • 0029114477 scopus 로고
    • Missense mutations of the transforming growth factor β type II receptor in human head and neck squamous carcinoma cells
    • Garrigue-Antar, L., Munoz-Antonia, T., Antonia, S.J., Gesmonde, J., Vellucci, V.F., and Reiss, M. (1995). Missense mutations of the transforming growth factor β type II receptor in human head and neck squamous carcinoma cells. Cancer Res. 55, 3982-3987.
    • (1995) Cancer Res. , vol.55 , pp. 3982-3987
    • Garrigue-Antar, L.1    Munoz-Antonia, T.2    Antonia, S.J.3    Gesmonde, J.4    Vellucci, V.F.5    Reiss, M.6
  • 36
  • 37
    • 0028171401 scopus 로고
    • Targeted deletion of the TGF-β1 gene causes rapid progression to squamous cell carcinoma
    • Glick, A.B., Lee, M.M., Darwiche, N., Kulkarni, A.B., Karlsson, S., and Yuspa, S.H. (1994). Targeted deletion of the TGF-β1 gene causes rapid progression to squamous cell carcinoma. Genes Dev. 8, 2429-2440.
    • (1994) Genes Dev. , vol.8 , pp. 2429-2440
    • Glick, A.B.1    Lee, M.M.2    Darwiche, N.3    Kulkarni, A.B.4    Karlsson, S.5    Yuspa, S.H.6
  • 38
    • 0024851629 scopus 로고
    • Expression of transforming growth factor α in normal adult kidney and enhanced expression of transforming growth factors α and β in renal cell carcinoma
    • Gomella, L.G., Sargent, E.R., Wade, T.P., Anglard, P., Linehan, W.M., and Kasid, A. (1989). Expression of transforming growth factor α in normal adult kidney and enhanced expression of transforming growth factors α and β in renal cell carcinoma. Cancer Res. 49, 6972-6975.
    • (1989) Cancer Res. , vol.49 , pp. 6972-6975
    • Gomella, L.G.1    Sargent, E.R.2    Wade, T.P.3    Anglard, P.4    Linehan, W.M.5    Kasid, A.6
  • 39
    • 0026801111 scopus 로고
    • Expression of α6β4 integrin increases during malignant conversion of mouse epidermal keratinocytes: Association of β4 subunit to the cytokeratin subfraction
    • Gomez, M., Navarro, P., Quintanilla, M., and Cano, A. (1992). Expression of α6β4 integrin increases during malignant conversion of mouse epidermal keratinocytes: association of β4 subunit to the cytokeratin subfraction. Exp. Cell Res. 201, 250-261.
    • (1992) Exp. Cell Res. , vol.201 , pp. 250-261
    • Gomez, M.1    Navarro, P.2    Quintanilla, M.3    Cano, A.4
  • 40
    • 0027053058 scopus 로고
    • Immunohistochemical staining for transforming growth factor β1 associates with disease progression in human breast cancer
    • Gorsch, S.M., Memoli, V.A., Stukel, T.A., Gold, L.I., and Arrick, B.A. (1992). Immunohistochemical staining for transforming growth factor β1 associates with disease progression in human breast cancer. Cancer Res. 52, 6949-6952.
    • (1992) Cancer Res. , vol.52 , pp. 6949-6952
    • Gorsch, S.M.1    Memoli, V.A.2    Stukel, T.A.3    Gold, L.I.4    Arrick, B.A.5
  • 41
    • 0025914188 scopus 로고
    • Loss of growth control by TGFβ occurs at a late stage of mouse carcinogenesis and is independent of ras gene activation
    • Haddow, S., Fowlis, D.J., Parkinson, K., Akhurst, R.J., and Balmain, A. (1991). Loss of growth control by TGFβ occurs at a late stage of mouse carcinogenesis and is independent of ras gene activation. Oncogene 6, 1465-1470.
    • (1991) Oncogene , vol.6 , pp. 1465-1470
    • Haddow, S.1    Fowlis, D.J.2    Parkinson, K.3    Akhurst, R.J.4    Balmain, A.5
  • 42
    • 0024788078 scopus 로고
    • Transforming growth factor-β switches the pattern of integrins expressed in MG-63 human osteosarcoma cells and causes a selective loss of cell adhesion to laminin
    • Heino, J., and Massague, J. (1989). Transforming growth factor-β switches the pattern of integrins expressed in MG-63 human osteosarcoma cells and causes a selective loss of cell adhesion to laminin. J. Biol. Chem. 36, 21806-21811.
    • (1989) J. Biol. Chem. , vol.36 , pp. 21806-21811
    • Heino, J.1    Massague, J.2
  • 44
    • 0024411678 scopus 로고
    • Integrin heterodimer and receptor complexity in avian and mammalian cells
    • Hynes, R.O., Marcantonio, E.E., Stepp, M.A., Urry, L.A., and Yee, G.H. (1989). Integrin heterodimer and receptor complexity in avian and mammalian cells. J. Cell Biol. 109, 409-420.
    • (1989) J. Cell Biol. , vol.109 , pp. 409-420
    • Hynes, R.O.1    Marcantonio, E.E.2    Stepp, M.A.3    Urry, L.A.4    Yee, G.H.5
  • 45
    • 0027199916 scopus 로고
    • Increased mannose 6-phosphate/insulin-like growth factor II receptor and transforming growth factor β1 levels during monoterpene-induced regression of mammary tumors
    • Jirtle, R.L., Haag, J.D., Ariazi, E.A., and Gould, M.N. (1993). Increased mannose 6-phosphate/insulin-like growth factor II receptor and transforming growth factor β1 levels during monoterpene-induced regression of mammary tumors. Cancer Res. 53, 3849-3852.
    • (1993) Cancer Res. , vol.53 , pp. 3849-3852
    • Jirtle, R.L.1    Haag, J.D.2    Ariazi, E.A.3    Gould, M.N.4
  • 46
    • 0025756331 scopus 로고
    • Secreted or non-secreted forms of acidic fibroblast growth factor produced by transfected epithelial cells influence cell morphology, motility and invasive potential
    • Jouanneau, J., Gavrilovic, J., Caruelle, D., Jaye, M., Moens, G., Caruelle, J.P., and Thiery, J.P. (1991a). Secreted or non-secreted forms of acidic fibroblast growth factor produced by transfected epithelial cells influence cell morphology, motility and invasive potential. Proc. Natl. Acad. Sci. USA 88, 2893-2897.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 2893-2897
    • Jouanneau, J.1    Gavrilovic, J.2    Caruelle, D.3    Jaye, M.4    Moens, G.5    Caruelle, J.P.6    Thiery, J.P.7
  • 48
    • 0028806184 scopus 로고
    • Abnormal lung development and cleft palate in mice lacking TGF-β3 indicates defects of epithelial-mesenchymal interaction
    • Kaartinen, V., Voncken, J.W., Shuler, C., Warburton, D., Bu, D., Heisterkamp, N., and Groffen, J. (1995). Abnormal lung development and cleft palate in mice lacking TGF-β3 indicates defects of epithelial-mesenchymal interaction. Nature Genet. 11, 415-421.
    • (1995) Nature Genet. , vol.11 , pp. 415-421
    • Kaartinen, V.1    Voncken, J.W.2    Shuler, C.3    Warburton, D.4    Bu, D.5    Heisterkamp, N.6    Groffen, J.7
  • 49
  • 50
    • 0023639110 scopus 로고
    • Synergistic induction of mesoderm by FGF and TGF-β and the identification of an mRNA coding for FGF in the early Xenopus embryo
    • Kimelman, D., and Kirschner, M. (1987). Synergistic induction of mesoderm by FGF and TGF-β and the identification of an mRNA coding for FGF in the early Xenopus embryo. Cell 51, 869-877.
    • (1987) Cell , vol.51 , pp. 869-877
    • Kimelman, D.1    Kirschner, M.2
  • 51
    • 0024469982 scopus 로고
    • Multistage chemical carcinogenesis protocols produce spindle cell carcinomas of the mouse skin
    • Klein-Szanto, A.J., Larcher, F., Bonfil, R.D., and Conti, C.J. (1989). Multistage chemical carcinogenesis protocols produce spindle cell carcinomas of the mouse skin. Carcinogenesis 10, 2169-2172.
    • (1989) Carcinogenesis , vol.10 , pp. 2169-2172
    • Klein-Szanto, A.J.1    Larcher, F.2    Bonfil, R.D.3    Conti, C.J.4
  • 52
    • 0025848971 scopus 로고
    • TGFβ1 and skin carcinogenesis: Antiproliferative effect in vitro and TGFβ1 mRNA during epidermal hyperproliferation and multistage tumorigenesis
    • Krieg, P., Schnapke, R., Furstenberger, G., Vogt, I., and Marks, F. (1991). TGFβ1 and skin carcinogenesis: antiproliferative effect in vitro and TGFβ1 mRNA during epidermal hyperproliferation and multistage tumorigenesis. Mol. Carcinog. 4, 129-137.
    • (1991) Mol. Carcinog. , vol.4 , pp. 129-137
    • Krieg, P.1    Schnapke, R.2    Furstenberger, G.3    Vogt, I.4    Marks, F.5
  • 53
    • 0019403692 scopus 로고
    • Sarcomatoid squamous cell carcinoma of the mucous membranes of the head and neck: A clinicopathologic study of 20 cases
    • Lenventon, G.S., and Evans, H.L. (1981). Sarcomatoid squamous cell carcinoma of the mucous membranes of the head and neck: a clinicopathologic study of 20 cases. Cancer 48, 994-1003.
    • (1981) Cancer , vol.48 , pp. 994-1003
    • Lenventon, G.S.1    Evans, H.L.2
  • 54
    • 0026584374 scopus 로고
    • In vitro apoptosis in the human hepatoma cell line induced by transforming growth factor β1
    • Lin, J., and Chou, C. (1992). In vitro apoptosis in the human hepatoma cell line induced by transforming growth factor β1. Cancer Res. 52, 385-388.
    • (1992) Cancer Res. , vol.52 , pp. 385-388
    • Lin, J.1    Chou, C.2
  • 55
    • 0025880223 scopus 로고
    • Differential sensitivity of human colonic adenoma and carcinoma cells to transforming growth factor β (TGF-β): Conversion of an adenoma cell line to a tumorigenic phenotype is accompanied by a reduced response to the inhibitory effects of TGF-β
    • Manning, A.M., Williams, A.C., Games, S.M., and Paraskeva, C. (1991). Differential sensitivity of human colonic adenoma and carcinoma cells to transforming growth factor β (TGF-β): conversion of an adenoma cell line to a tumorigenic phenotype is accompanied by a reduced response to the inhibitory effects of TGF-β. Oncogene 6, 1471-1476.
    • (1991) Oncogene , vol.6 , pp. 1471-1476
    • Manning, A.M.1    Williams, A.C.2    Games, S.M.3    Paraskeva, C.4
  • 56
    • 0027193233 scopus 로고
    • Expression of E-cadherin in embryogenetic ingression and cancer invasion
    • Mareel, M., Bracke, M., Van Roy, F., and Vakaet, L. (1993). Expression of E-cadherin in embryogenetic ingression and cancer invasion. Int. J. Dev. Biol. 37, 227-235.
    • (1993) Int. J. Dev. Biol. , vol.37 , pp. 227-235
    • Mareel, M.1    Bracke, M.2    Van Roy, F.3    Vakaet, L.4
  • 58
    • 0028603343 scopus 로고
    • TGF-β induced transdifferentiation of mammary epithelial cells to mesenchymal cells: Involvement of type I receptors
    • Miettinen, P.J., Ebner, R., Lopez, A.R., and Derynck, R. (1994). TGF-β induced transdifferentiation of mammary epithelial cells to mesenchymal cells: involvement of type I receptors. J. Cell Biol. 127, 2021-2036.
    • (1994) J. Cell Biol. , vol.127 , pp. 2021-2036
    • Miettinen, P.J.1    Ebner, R.2    Lopez, A.R.3    Derynck, R.4
  • 59
    • 0025977578 scopus 로고
    • Embryonic expression patterns of TGFβ1, 2 and 3 suggest different functions in vivo
    • Millan, F.A., Kondaiah, P., Denhez, F., and Akhurst, R.J. (1991). Embryonic expression patterns of TGFβ1, 2 and 3 suggest different functions in vivo. Development 111, 131-144.
    • (1991) Development , vol.111 , pp. 131-144
    • Millan, F.A.1    Kondaiah, P.2    Denhez, F.3    Akhurst, R.J.4
  • 60
    • 0026004630 scopus 로고
    • Escape from transforming growth factor β control and oncogene cooperation in skin tumor development
    • Missero, C., Cajal, S.R.Y., and Dotto, G.P. (1991). Escape from transforming growth factor β control and oncogene cooperation in skin tumor development. Proc. Natl. Acad. Sci. USA 88, 9613-9617.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 9613-9617
    • Missero, C.1    Cajal, S.R.Y.2    Dotto, G.P.3
  • 61
    • 0020403245 scopus 로고
    • Keratin modifications in epidermis, papillomas, and carcinomas during two-stage carcinogenesis in the SENCAR mouse
    • Nelson, K.G., and Slaga, T.J. (1982). Keratin modifications in epidermis, papillomas, and carcinomas during two-stage carcinogenesis in the SENCAR mouse. Cancer Res. 42, 4176-4181.
    • (1982) Cancer Res. , vol.42 , pp. 4176-4181
    • Nelson, K.G.1    Slaga, T.J.2
  • 62
    • 0024271965 scopus 로고
    • Aberrant expression during two-stage mouse skin carcinogenesis of a type I 47 kDa keratin, K13, normally associated with terminal differentiation of internal stratified epithelia
    • Nischt, R., Roop, D.R., Mehrel, T., Yuspa, S.H., Rentrop, M., Winter, H., and Schweizer, J. (1988). Aberrant expression during two-stage mouse skin carcinogenesis of a type I 47 kDa keratin, K13, normally associated with terminal differentiation of internal stratified epithelia. Mol. Carcinog. 1, 96-108.
    • (1988) Mol. Carcinog. , vol.1 , pp. 96-108
    • Nischt, R.1    Roop, D.R.2    Mehrel, T.3    Yuspa, S.H.4    Rentrop, M.5    Winter, H.6    Schweizer, J.7
  • 63
    • 0025018368 scopus 로고
    • Differential expression of genes encoding TGFs β1, β2, and β3 during murine palate formation
    • Pelton, R.W., Hogan, B.L., Miller, D.A., and Moses, H.L. (1990). Differential expression of genes encoding TGFs β1, β2, and β3 during murine palate formation. Dev. Biol. 141, 456-460.
    • (1990) Dev. Biol. , vol.141 , pp. 456-460
    • Pelton, R.W.1    Hogan, B.L.2    Miller, D.A.3    Moses, H.L.4
  • 65
    • 0024413336 scopus 로고
    • Epithelial-mesenchymal cell transformation in the embryonic heart can be mediated, in part, by transforming growth factor β
    • Potts, J.D., and Runyan, R.B. (1989). Epithelial-mesenchymal cell transformation in the embryonic heart can be mediated, in part, by transforming growth factor β. Dev. Biol. 134, 392-401.
    • (1989) Dev. Biol. , vol.134 , pp. 392-401
    • Potts, J.D.1    Runyan, R.B.2
  • 67
    • 0000116653 scopus 로고
    • The transforming growth factor βs
    • M.B. Sporn and A.B. Roberts, eds. (Heidelberg, Federal Republic of Germany: Springer-Verlag)
    • Roberts, A.B., and Sporn, M.B. (1990). The transforming growth factor βs. In Peptide Growth Factors and Their Receptors: Handbook of Experimental Pharmacology, M.B. Sporn and A.B. Roberts, eds. (Heidelberg, Federal Republic of Germany: Springer-Verlag), pp. 419-472.
    • (1990) Peptide Growth Factors and Their Receptors: Handbook of Experimental Pharmacology , pp. 419-472
    • Roberts, A.B.1    Sporn, M.B.2
  • 69
    • 0023898669 scopus 로고
    • Transcriptional control of high molecular weight keratin gene expression in multistage mouse skin carcinogenesis
    • Roop, D.R., Krieg, T.M., Mehrel, T., Cheng, C.K., and Yuspa, S.H. (1988). Transcriptional control of high molecular weight keratin gene expression in multistage mouse skin carcinogenesis. Cancer Res. 48, 3245-3252.
    • (1988) Cancer Res. , vol.48 , pp. 3245-3252
    • Roop, D.R.1    Krieg, T.M.2    Mehrel, T.3    Cheng, C.K.4    Yuspa, S.H.5
  • 70
    • 0026318253 scopus 로고
    • Coordinated regulation of apoptosis and cell proliferation by transforming growth factor β1 in cultured uterine epithelial cells
    • Rotello, R.J., Leiberman, R.C., Purchio, A.F., and Gerschenson, L.E. (1991). Coordinated regulation of apoptosis and cell proliferation by transforming growth factor β1 in cultured uterine epithelial cells. Proc. Natl. Acad. Sci. USA 88, 3412-3415.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 3412-3415
    • Rotello, R.J.1    Leiberman, R.C.2    Purchio, A.F.3    Gerschenson, L.E.4
  • 71
    • 0026535245 scopus 로고
    • Autocrine induction and tumour protease production and invasion by a metalloproteinase-regulated TGFβ1
    • Samuel, S.R., Hurta, R.A.R., Kondaiah, P., Khalil, N., Turley, E.A., Wright, J.A., and Greenberg, A.H. (1992). Autocrine induction and tumour protease production and invasion by a metalloproteinase-regulated TGFβ1. EMBO J. 11, 1599-1605.
    • (1992) EMBO J. , vol.11 , pp. 1599-1605
    • Samuel, S.R.1    Hurta, R.A.R.2    Kondaiah, P.3    Khalil, N.4    Turley, E.A.5    Wright, J.A.6    Greenberg, A.H.7
  • 73
    • 0025354027 scopus 로고
    • Mediation of wound-related rous sarcoma virus tumorigenesis by TGF-β
    • Sieweke, M.H., Thompson, N.L., Sporn, M.B., and Bissell, M.J. (1990). Mediation of wound-related Rous sarcoma virus tumorigenesis by TGF-β. Science 248, 1656-1660.
    • (1990) Science , vol.248 , pp. 1656-1660
    • Sieweke, M.H.1    Thompson, N.L.2    Sporn, M.B.3    Bissell, M.J.4
  • 74
    • 0026600577 scopus 로고
    • Transforming growth factor-β-1 overproduction in prostate cancer: Effects on growth in vivo and in vitro
    • Steiner, M.S., and Barrack, E.R. (1992). Transforming growth factor-β-1 overproduction in prostate cancer: effects on growth in vivo and in vitro. Mol. Endocrinol. 6, 15-25.
    • (1992) Mol. Endocrinol. , vol.6 , pp. 15-25
    • Steiner, M.S.1    Barrack, E.R.2
  • 75
    • 0027200650 scopus 로고
    • The conversion of mouse skin squamous cell carcinomas to spindle cell carcinomas is a recessive event
    • Stoler, A., Stenback, F., and Balmain, A. (1993). The conversion of mouse skin squamous cell carcinomas to spindle cell carcinomas is a recessive event. J. Cell Biol. 122, 1103-1117.
    • (1993) J. Cell Biol. , vol.122 , pp. 1103-1117
    • Stoler, A.1    Stenback, F.2    Balmain, A.3
  • 77
    • 0026629402 scopus 로고
    • Extracellular matrix receptors and mouse skin carcinogenesis: Altered expression linked to early markers of tumor progression
    • Tennenbaum, T., Yuspa, S.H., Grover, A., Castronovo, V., Sobel, M.E., Yamada, Y., and DeLuca, L.M. (1992). Extracellular matrix receptors and mouse skin carcinogenesis: altered expression linked to early markers of tumor progression. Cancer Res. 52, 2966-2976.
    • (1992) Cancer Res. , vol.52 , pp. 2966-2976
    • Tennenbaum, T.1    Yuspa, S.H.2    Grover, A.3    Castronovo, V.4    Sobel, M.E.5    Yamada, Y.6    DeLuca, L.M.7
  • 78
    • 0027491154 scopus 로고
    • The suprabasal expression of α6β4 integrin is associated with a high risk for malignant progression in mouse skin carcinogenesis
    • Tennenbaum, T., Weiner, A.K., Belanger, A.J., Glick, A.B., Henning, H., and Yuspa, S.H. (1993). The suprabasal expression of α6β4 integrin is associated with a high risk for malignant progression in mouse skin carcinogenesis. Cancer Res. 53, 4803-4810.
    • (1993) Cancer Res. , vol.53 , pp. 4803-4810
    • Tennenbaum, T.1    Weiner, A.K.2    Belanger, A.J.3    Glick, A.B.4    Henning, H.5    Yuspa, S.H.6
  • 79
    • 0024381057 scopus 로고
    • Changes in response to, and production of, transforming growth factor type β during neoplastic progression in cultured rat tracheal epithelial cells
    • Terzaghi-Howe, M. (1989). Changes in response to, and production of, transforming growth factor type β during neoplastic progression in cultured rat tracheal epithelial cells. Carcinogenesis 10, 973-980.
    • (1989) Carcinogenesis , vol.10 , pp. 973-980
    • Terzaghi-Howe, M.1
  • 80
    • 0022339811 scopus 로고
    • Keratin gene expression in mouse skin tumors and in mouse skin treated with 12-O-tetradecanoylphorbol-13-acetate
    • Toftgard, R., Yuspa, S.H., and Roop, D.R. (1985). Keratin gene expression in mouse skin tumors and in mouse skin treated with 12-O-tetradecanoylphorbol-13-acetate. Cancer Res. 45, 5845-5850.
    • (1985) Cancer Res. , vol.45 , pp. 5845-5850
    • Toftgard, R.1    Yuspa, S.H.2    Roop, D.R.3
  • 82
    • 0029065125 scopus 로고
    • Mesoderm induction in Xenopus caused by activation of MAP kinase
    • Umbhauer, M., Marshall, C.J., Mason, C.S., Old, R.W., and Smith, J.C. (1995). Mesoderm induction in Xenopus caused by activation of MAP kinase. Nature 376, 58-62.
    • (1995) Nature , vol.376 , pp. 58-62
    • Umbhauer, M.1    Marshall, C.J.2    Mason, C.S.3    Old, R.W.4    Smith, J.C.5
  • 83
    • 0026066351 scopus 로고
    • Adhesion systems in embryonic epithelial-to-mesenchyme transformation and in cancer invasion and metastasis
    • Valles, A.M., Boyer, B., and Thierry, J.P. (1991). Adhesion systems in embryonic epithelial-to-mesenchyme transformation and in cancer invasion and metastasis. Experimentia 59 (Suppl.), 17-34.
    • (1991) Experimentia , vol.59 , Issue.SUPPL. , pp. 17-34
    • Valles, A.M.1    Boyer, B.2    Thierry, J.P.3
  • 84
    • 0023604578 scopus 로고
    • Distribution and modulation of the cellular receptor for transforming growth factor-β
    • Wakefield, L.M., Smith, D.M., Masui, T., Harris, C.C., and Sporn, M.B. (1987). Distribution and modulation of the cellular receptor for transforming growth factor-β. J. Cell Biol. 105, 965-975.
    • (1987) J. Cell Biol. , vol.105 , pp. 965-975
    • Wakefield, L.M.1    Smith, D.M.2    Masui, T.3    Harris, C.C.4    Sporn, M.B.5
  • 85
    • 0025632985 scopus 로고
    • Recombinant latent transforming growth factor β1 has a longer plasma half-life in rats than transforming growth factor β1, and a different tissue distribution
    • Wakefield, L.M., Winokur, T.S., Hollands, R.S., Christopherson, K., Levinson, A.D., and Sporn, M.B. (1990). Recombinant latent transforming growth factor β1 has a longer plasma half-life in rats than transforming growth factor β1, and a different tissue distribution. J. Clin. Invest. 86, 1976-1984.
    • (1990) J. Clin. Invest. , vol.86 , pp. 1976-1984
    • Wakefield, L.M.1    Winokur, T.S.2    Hollands, R.S.3    Christopherson, K.4    Levinson, A.D.5    Sporn, M.B.6
  • 86
    • 0029017485 scopus 로고
    • Autocrine transforming growth factor β1 modulates the expression of integrin α5β1 in human colon carcinoma FET cells
    • Wang, D., Zhou, G., Birkenmeier, T.M., Gong, J., Sun, L., and Brattain, M.G. (1995). Autocrine transforming growth factor β1 modulates the expression of integrin α5β1 in human colon carcinoma FET cells. J. Biol. Chem. 270, 14154-14159.
    • (1995) J. Biol. Chem. , vol.270 , pp. 14154-14159
    • Wang, D.1    Zhou, G.2    Birkenmeier, T.M.3    Gong, J.4    Sun, L.5    Brattain, M.G.6
  • 87
    • 11944255353 scopus 로고
    • Transforming growth factor β1 stimulates mammary adenocarcinoma cell invasion and metastatic potential
    • Welch, D.R., Fabra, A., and Nakajima, M. (1990). Transforming growth factor β1 stimulates mammary adenocarcinoma cell invasion and metastatic potential. Proc. Natl. Acad. Sci. USA 87, 7678-7682.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 7678-7682
    • Welch, D.R.1    Fabra, A.2    Nakajima, M.3
  • 88
    • 0026611442 scopus 로고
    • Involvement of p21 (ras) in Xenopus mesoderm induction
    • Whitman, M., and Melton, M.S. (1992). Involvement of p21 (ras) in Xenopus mesoderm induction. Nature 357, 252-254.
    • (1992) Nature , vol.357 , pp. 252-254
    • Whitman, M.1    Melton, M.S.2
  • 89
    • 0019277862 scopus 로고
    • Keratins as markers of malignancy in mouse epidermal tumors
    • Winter, H., Schweizer, J., and Goerttler, K. (1980). Keratins as markers of malignancy in mouse epidermal tumors. Carcinogenesis 1, 391-398.
    • (1980) Carcinogenesis , vol.1 , pp. 391-398
    • Winter, H.1    Schweizer, J.2    Goerttler, K.3
  • 90
    • 0028330752 scopus 로고
    • Complex patterns of expression suggest roles for the α2β1 integrin in murine development
    • Wu, J.E., and Santoro, S.A. (1994). Complex patterns of expression suggest roles for the α2β1 integrin in murine development. Dev. Dyn. 199, 292-314.
    • (1994) Dev. Dyn. , vol.199 , pp. 292-314
    • Wu, J.E.1    Santoro, S.A.2
  • 91
    • 0026513154 scopus 로고
    • TGF-β 1 is an autocrine-negative growth regulator of human colon carcinoma FET cells in vivo as revealed by transfection of an antisense expression vector
    • Wu, S.P., Theodoresou, D., Kerbel, R.S., Willson, J.K., Mulder, K.M., Humphrey, L.E., and Brattain, M.G. (1992). TGF-β 1 is an autocrine-negative growth regulator of human colon carcinoma FET cells in vivo as revealed by transfection of an antisense expression vector. J. Cell Biol. 116, 187-196.
    • (1992) J. Cell Biol. , vol.116 , pp. 187-196
    • Wu, S.P.1    Theodoresou, D.2    Kerbel, R.S.3    Willson, J.K.4    Mulder, K.M.5    Humphrey, L.E.6    Brattain, M.G.7
  • 92
    • 0027548803 scopus 로고
    • Repression of autocrine transforming growth factor β1 and β2 in quiescent CBS colon carcinoma cells leads to progression of tumorigenic properties
    • Wu, S.P., Sun, L., Willson, J.K.V., Humphrey, L., Kerbel, K., and Brattain, M.G. (1993). Repression of autocrine transforming growth factor β1 and β2 in quiescent CBS colon carcinoma cells leads to progression of tumorigenic properties. Cell Growth Differ. 4, 115-123.
    • (1993) Cell Growth Differ. , vol.4 , pp. 115-123
    • Wu, S.P.1    Sun, L.2    Willson, J.K.V.3    Humphrey, L.4    Kerbel, K.5    Brattain, M.G.6


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