-
1
-
-
0030922980
-
Characterization of functional domains within Smad4/DPC4
-
DE CAESTECKER, M.P., HEMMATI, P., LARISCH-BLOCH, S., AJMERA, R., ROBERTS, A.B. and LECHLEIDER, R.J., Characterization of functional domains within Smad4/DPC4. J. Biol. Chem., 272, 13690-13696 (1997).
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 13690-13696
-
-
De Caestecker, M.P.1
Hemmati, P.2
Larisch-Bloch, S.3
Ajmera, R.4
Roberts, A.B.5
Lechleider, R.J.6
-
2
-
-
0030963943
-
DPC4 (SMAD4) mediates transforming growth factor-betal (TGF-betal) induced growth inhibition and transcriptional response in breast tumour cells
-
DE WINTER, J.P., ROELEN, B.A., TEN DIJKE, P., VAN DER BURG, B. and VAN DEN EIJNDEN-VAN RAAIJ, A.J., DPC4 (SMAD4) mediates transforming growth factor-betal (TGF-betal) induced growth inhibition and transcriptional response in breast tumour cells. Oncogene, 14, 1891-1899 (1997).
-
(1997)
Oncogene
, vol.14
, pp. 1891-1899
-
-
De Winter, J.P.1
Roelen, B.A.2
Ten Dijke, P.3
Van Der Burg, B.4
Van Den Eijnden-van Raaij, A.J.5
-
3
-
-
0032101178
-
Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene
-
DENNLER, S., ITOH, S., VIVIEN, D., TEN DIJKE, P., HUET, S. and GAUTHIER, J.M., Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene. EMBO J., 17, 3091-3100 (1998).
-
(1998)
EMBO J.
, vol.17
, pp. 3091-3100
-
-
Dennler, S.1
Itoh, S.2
Vivien, D.3
Ten Dijke, P.4
Huet, S.5
Gauthier, J.M.6
-
4
-
-
16044369574
-
MADR2 maps to 18q21 and encodes a TGF-ßeta-regulated MAD-related protein that is functionally mutated in colorectal carcinoma
-
EPPERT, K. and 12 OTHERS, MADR2 maps to 18q21 and encodes a TGF-ßeta-regulated MAD-related protein that is functionally mutated in colorectal carcinoma. Cell, 86, 543-552 (1996).
-
(1996)
Cell
, vol.86
, pp. 543-552
-
-
Eppert, K.1
-
5
-
-
0032520915
-
Mutations of the DPC4/Smad4 gene in biliary tract carcinoma
-
HAHN, S.A., BARTSCH, D., SCHROERS, A., GALEHDARI, H., BECKER, M., RAMASWAMY, A., SCHWARTE-WALDHOFF, I., MASCHEK, H. and SCHMIEGEL, W., Mutations of the DPC4/Smad4 gene in biliary tract carcinoma. Cancer Res., 58, 1124-1126 (1998).
-
(1998)
Cancer Res.
, vol.58
, pp. 1124-1126
-
-
Hahn, S.A.1
Bartsch, D.2
Schroers, A.3
Galehdari, H.4
Becker, M.5
Ramaswamy, A.6
Schwarte-Waldhoff, I.7
Maschek, H.8
Schmiegel, W.9
-
6
-
-
0030593038
-
DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1
-
HAHN, S.A., SCHUTTE, M., HOQUE, A.T., MOSKALUK, CA., DA COSTA, L.T., ROZENBLUM, E., WEINSTEIN, C.L., FISCHER, A., YEO, C.J., HRUBAN, R.H. and KERN, S.E., DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1. Science, 271, 350-353 (1996).
-
(1996)
Science
, vol.271
, pp. 350-353
-
-
Hahn, S.A.1
Schutte, M.2
Hoque, A.T.3
Moskaluk, C.A.4
Da Costa, L.T.5
Rozenblum, E.6
Weinstein, C.L.7
Fischer, A.8
Yeo, C.J.9
Hruban, R.H.10
Kern, S.E.11
-
7
-
-
0030825516
-
Mutations increasing autoinhibition inactivate tumour suppressors Smad2 and Smad4
-
HATA, A., Lo, R.S., WOTTON, D., LANGA, G. and MASSAGUE, J., Mutations increasing autoinhibition inactivate tumour suppressors Smad2 and Smad4. Nature (Land.), 388, 82-87 (1997).
-
(1997)
Nature (Land.)
, vol.388
, pp. 82-87
-
-
Hata, A.1
Lo, R.S.2
Wotton, D.3
Langa, G.4
Massague, J.5
-
8
-
-
0031438047
-
TGF-ßeta signalling from cell membrane to nucleus through SMAD proteins
-
HELDIN, C.H., MIYAZONO, K. and TEN DUKE, P., TGF-ßeta signalling from cell membrane to nucleus through SMAD proteins. Nature (Lond.), 390, 465-471 (1997).
-
(1997)
Nature (Lond.)
, vol.390
, pp. 465-471
-
-
Heldin, C.H.1
Miyazono, K.2
Ten Duke, P.3
-
9
-
-
0032498326
-
DPC4 splice variants in neuroblastoma
-
KAGEYAMA, H., SEKI, N., YAMADA, S., SAKIYAMA, S. and NAKAGAWARA, A., DPC4 splice variants in neuroblastoma. Cancer Lett., 122, 187-193 (1998).
-
(1998)
Cancer Lett.
, vol.122
, pp. 187-193
-
-
Kageyama, H.1
Seki, N.2
Yamada, S.3
Sakiyama, S.4
Nakagawara, A.5
-
10
-
-
0032474868
-
The oncoprotein Evi-1 represses TGF-ß signalling by inhibiting Smad3
-
KUROKAWA, M., MITANI, K., IRIE. K., MATSUYAMA, T., TAKAHASHI, T., CHIBA, S., YAZAKI, Y., MATSUMOTO, K. and HIRAI, H., The oncoprotein Evi-1 represses TGF-ß signalling by inhibiting Smad3. Nature (Lond.), 394, 92-96 (1998).
-
(1998)
Nature (Lond.)
, vol.394
, pp. 92-96
-
-
Kurokawa, M.1
Mitani, K.2
Irie, K.3
Matsuyama, T.4
Takahashi, T.5
Chiba, S.6
Yazaki, Y.7
Matsumoto, K.8
Hirai, H.9
-
11
-
-
0025933890
-
Multiple K-ras codon 12 mutations in cholangiocarcinomas demonstrated with a sensitive polymerase chain reaction technique
-
LEVI, S., URBANO-ISPIZUA, A., GILL, R., THOMAS, D.M., GILBERTSON, J., FOSTER, C. and MARSHALL, C.J., Multiple K-ras codon 12 mutations in cholangiocarcinomas demonstrated with a sensitive polymerase chain reaction technique. Cancer Res., 51, 3497-3502 (1991).
-
(1991)
Cancer Res.
, vol.51
, pp. 3497-3502
-
-
Levi, S.1
Urbano-Ispizua, A.2
Gill, R.3
Thomas, D.M.4
Gilbertson, J.5
Foster, C.6
Marshall, C.J.7
-
12
-
-
0032481351
-
The L3 loop: A structural motif determining specific interactions between SMAD proteins and TGF-ßeta receptors
-
Lo, R.S., CHEN, Y.G., SHI, Y., PAVLETICH, N.P. and MASSAGUÉ. J., The L3 loop: A structural motif determining specific interactions between SMAD proteins and TGF-ßeta receptors. Embo J., 17, 996-1005 (1998).
-
(1998)
Embo J.
, vol.17
, pp. 996-1005
-
-
Lo, R.S.1
Chen, Y.G.2
Shi, Y.3
Pavletich, N.P.4
Massagué, J.5
-
13
-
-
0028210001
-
Transforming growth factor beta 1 secreted from scirrhous gastric cancer cells is associated with excess collagen deposition in the tissue
-
MAHARA, K., KATO, J., TERUI, T., TAKIMOTO, R., HORIMOTO, M., MURAKAMI, T., MOGI, Y., WATANABE, N., KOHGO, Y. and NIITSU, Y., Transforming growth factor beta 1 secreted from scirrhous gastric cancer cells is associated with excess collagen deposition in the tissue. Br. J. Cancer, 69, 777-783 (1994).
-
(1994)
Br. J. Cancer
, vol.69
, pp. 777-783
-
-
Mahara, K.1
Kato, J.2
Terui, T.3
Takimoto, R.4
Horimoto, M.5
Murakami, T.6
Mogi, Y.7
Watanabe, N.8
Kohgo, Y.9
Niitsu, Y.10
-
14
-
-
0028785603
-
Microsatellite instability and mutations of the transforming growth factor beta type II receptor gene in colorectal cancer
-
PARSONS, R., MYEROFF, L.L., LIU, B., WILLSON, J.K., MARKOWITZ, S.D., KINZLER, K.W. and VOGELSTEIN, B., Microsatellite instability and mutations of the transforming growth factor beta type II receptor gene in colorectal cancer. Cancer Res., 55, 5548-5550 (1995).
-
(1995)
Cancer Res.
, vol.55
, pp. 5548-5550
-
-
Parsons, R.1
Myeroff, L.L.2
Liu, B.3
Willson, J.K.4
Markowitz, S.D.5
Kinzler, K.W.6
Vogelstein, B.7
-
15
-
-
0032943080
-
Expression of transforming-growth-factor (TGF)-ß receptors and SMAD proteins in glioblastoma cell lines with distinct response to TGF-ß1
-
PIEK, E., WESTERMARK, U., KASTEMAR, M., HELDIN, C.H., VAN ZOELEN, E.J., NISTER, M. and TEN DIJKE, P.T., Expression of transforming-growth-factor (TGF)-ß receptors and SMAD proteins in glioblastoma cell lines with distinct response to TGF-ß1. Int. J. Cancer, 80, 756-763 (1999).
-
(1999)
Int. J. Cancer
, vol.80
, pp. 756-763
-
-
Piek, E.1
Westermark, U.2
Kastemar, M.3
Heldin, C.H.4
Van Zoelen, E.J.5
Nister, M.6
Ten Dijke, P.T.7
-
16
-
-
0029180204
-
Malignancies of the biliary tract
-
S.A. Wells (ed.), Mosby-Yearbook, St. Louis
-
PITT, H.A., DOOLEY, W.C., YEO, C.J., CAMERON, J.L., Malignancies of the biliary tract. In: S.A. Wells (ed.), Current problems in surgery, Vol. 32, pp. 6-90. Mosby-Yearbook, St. Louis (1995).
-
(1995)
Current Problems in Surgery
, vol.32
, pp. 6-90
-
-
Pitt, H.A.1
Dooley, W.C.2
Yeo, C.J.3
Cameron, J.L.4
-
17
-
-
0000778479
-
Analysis of RNA
-
2nd Ed., Cold Spring Harbor Laboratory Press, New York
-
SAMBROOK, J., FRITSCH, E.F., and MANIATIS, T., Analysis of RNA. In: Molecular cloning, Vol. 1, 2nd Ed., pp. 7.37-7.52. Cold Spring Harbor Laboratory Press, New York (1989).
-
(1989)
Molecular Cloning
, vol.1
, pp. 737-752
-
-
Sambrook, J.1
Fritsch, E.F.2
Maniatis, T.3
-
18
-
-
0022446645
-
Transforming growth factor-beta: Biological function and chemical structure
-
SPORN, M.B., ROBERTS, A.B., WAKEFIELD, L.M. and ASSOIAN, R.K., Transforming growth factor-beta: Biological function and chemical structure. Science, 233, 532-534 (1986).
-
(1986)
Science
, vol.233
, pp. 532-534
-
-
Sporn, M.B.1
Roberts, A.B.2
Wakefield, L.M.3
Assoian, R.K.4
-
19
-
-
0032489508
-
Intestinal tumorigenesis in compound mutant mice of both Dpc4 (Smad4) and Apc genes
-
TAKAKU, K., OSHIMA, M., MIYOSHI, H., MATSUI, M., SELDIN, M.F. and TAKETO, M.M., Intestinal tumorigenesis in compound mutant mice of both Dpc4 (Smad4) and Apc genes. Cell, 92, 645-656 (1998).
-
(1998)
Cell
, vol.92
, pp. 645-656
-
-
Takaku, K.1
Oshima, M.2
Miyoshi, H.3
Matsui, M.4
Seldin, M.F.5
Taketo, M.M.6
-
20
-
-
0031843618
-
Mutation analysis of the Smad2 gene in human colon cancers using genomic DNA and intron primers
-
TAKENOSHITA, S., TANI, M., MOGI, A., NAGASHIMA, M., NAGAMACHI, Y., BENNETT, W.P., HAGIWARA, K., HARRIS, C.C. and YOKOTA, J., Mutation analysis of the Smad2 gene in human colon cancers using genomic DNA and intron primers. Carcinogenesis, 19, 803-807 (1998).
-
(1998)
Carcinogenesis
, vol.19
, pp. 803-807
-
-
Takenoshita, S.1
Tani, M.2
Mogi, A.3
Nagashima, M.4
Nagamachi, Y.5
Bennett, W.P.6
Hagiwara, K.7
Harris, C.C.8
Yokota, J.9
-
21
-
-
0028105888
-
An immunohistochemical study of p53 protein in gallbladder and extrahepatic bile duct/ampullary carcinomas
-
TEH, M., WEE, A. and RAJU, G.C., An immunohistochemical study of p53 protein in gallbladder and extrahepatic bile duct/ampullary carcinomas. Cancer, 74, 1542-1545 (1994).
-
(1994)
Cancer
, vol.74
, pp. 1542-1545
-
-
Teh, M.1
Wee, A.2
Raju, G.C.3
-
22
-
-
0029773770
-
A transforming growth factor beta type II receptor gene mutation common in sporadic cecum cancer with microsatellite instability
-
TOGO, G., TODA, N., KANAI, F., KATO, N., SHIRATORI, Y., KISHI, K., IMAZEKI, F., MAKUUCHI, M. and OMATA, M., A transforming growth factor beta type II receptor gene mutation common in sporadic cecum cancer with microsatellite instability. Cancer Res., 56, 5620-5623 (1996).
-
(1996)
Cancer Res.
, vol.56
, pp. 5620-5623
-
-
Togo, G.1
Toda, N.2
Kanai, F.3
Kato, N.4
Shiratori, Y.5
Kishi, K.6
Imazeki, F.7
Makuuchi, M.8
Omata, M.9
-
23
-
-
0030849060
-
Mutation analysis of the transforming growth factor-beta type II receptor in human cell lines resistant to growth inhibition by transforming growth factor-beta
-
VINCENT, F., NAGASHIMA, M., TAKENOSHITA, S., KHAN, M.A., GEMMA, A., HAGIWARA, K. and BENNETT, W.P., Mutation analysis of the transforming growth factor-beta type II receptor in human cell lines resistant to growth inhibition by transforming growth factor-beta. Oncogene. 15, 117-122 (1997).
-
(1997)
Oncogene
, vol.15
, pp. 117-122
-
-
Vincent, F.1
Nagashima, M.2
Takenoshita, S.3
Khan, M.A.4
Gemma, A.5
Hagiwara, K.6
Bennett, W.P.7
-
24
-
-
0030056048
-
Reduced expression of transforming growth factor beta type I receptor contributes to the malignancy of human colon carcinoma cells
-
WANG, J., HAN, W., ZBOROWSKA, E., LIANG, J., WANG, X., WILLSON, J.K. V., SUN, L. and BRATTAIN, M.G., Reduced expression of transforming growth factor beta type I receptor contributes to the malignancy of human colon carcinoma cells. J. Biol. Chem., 271, 17366-17371 (1996).
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 17366-17371
-
-
Wang, J.1
Han, W.2
Zborowska, E.3
Liang, J.4
Wang, X.5
Willson, J.K.V.6
Sun, L.7
Brattain, M.G.8
-
25
-
-
0028981089
-
Mutations of p16Ink4/CDKN2 and p15Ink4BMTS2 genes in biliary tract cancers
-
YOSHIDA, S., TODOROKI, T., ICHIKAWA, Y., HANAI, S., SUZUKI, H., HORI, M., FUKAO, K., MIWA, M. and UCHIDA, K., Mutations of p16Ink4/CDKN2 and p15Ink4BMTS2 genes in biliary tract cancers. Cancer Res., 55, 2756-2760 (1995).
-
(1995)
Cancer Res.
, vol.55
, pp. 2756-2760
-
-
Yoshida, S.1
Todoroki, T.2
Ichikawa, Y.3
Hanai, S.4
Suzuki, H.5
Hori, M.6
Fukao, K.7
Miwa, M.8
Uchida, K.9
-
26
-
-
0032544448
-
Smad3 mutant mice develop metastatic colorectal cancer
-
ZHU, Y., RICHARDSON, J.A., PARADA, L.F. and GRAFF, J.M., Smad3 mutant mice develop metastatic colorectal cancer. Cell, 94, 703-714 (1998).
-
(1998)
Cell
, vol.94
, pp. 703-714
-
-
Zhu, Y.1
Richardson, J.A.2
Parada, L.F.3
Graff, J.M.4
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