The TGF-β signaling inhibitor Smad7 enhances tumorigenicity in pancreatic cancer

Oncogene

Volumn 18, Issue 39, 1999, Pages 5363-5372

  Kleeff, J ^a   Ishiwata, T ^a   Maruyama, H ^a   Friess, H ^b   Truong, P ^a   Buchler M W ^b   Falb, D ^c,d   Korc, M ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF BERN   (Switzerland)

^c MILLENNIUM PHARMACEUTICALS INC   (United States)

^d Praecis Pharmaceuticals   (United States)

Author keywords

Cancer; Pancreas; Smad7; TGF

Indexed keywords

MESSENGER RNA; PROTEIN; SMAD PROTEIN; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; UNCLASSIFIED DRUG;

ADOLESCENT; ADULT; AGED; ARTICLE; CANCER CELL; CARCINOGENICITY; CELL NUCLEUS; COMPARATIVE STUDY; CONTROLLED STUDY; FEMALE; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN TISSUE; IN SITU HYBRIDIZATION; MALE; PANCREAS CANCER; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANIMALS; CELL DIVISION; DNA-BINDING PROTEINS; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MALE; MICE; MICE, NUDE; MIDDLE AGED; NEOPLASM TRANSPLANTATION; PANCREAS; PANCREATIC NEOPLASMS; PLASMINOGEN ACTIVATOR INHIBITOR 1; RNA, MESSENGER; SIGNAL TRANSDUCTION; SMAD7 PROTEIN; TRANS-ACTIVATORS; TRANSFORMING GROWTH FACTOR BETA; TUMOR CELLS, CULTURED;

EID: 0033598408     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1202909     Document Type: Article

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