The expression of vascular endothelial growth factor and transforming growth factor-β associates with angiogenesis in epithelial ovarian cancer

International Journal of Gynecological Pathology

Volumn 16, Issue 3, 1997, Pages 256-262

  Nakanishi, Yoshie ^a   Kodama, Junichi ^a   Yoshinouchi, Mitsuo ^a   Tokumo, Keizo ^a   Kamimura, Shigehito ^a   Okuda, Hiroyuki ^a   Kudo, Takafumi ^a  

^a OKAYAMA UNIVERSITY MEDICAL SCHOOL   (Japan)

Author keywords

Angiogenesis VEGF; Epithelial ovarian cancer; TGF

Indexed keywords

TRANSFORMING GROWTH FACTOR BETA; VASCULOTROPIN; VON WILLEBRAND FACTOR;

ANGIOGENESIS; ARTICLE; CANCER SURVIVAL; FEMALE; GENE EXPRESSION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MICROVASCULATURE; NEOVASCULARIZATION (PATHOLOGY); OVARY CANCER; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION;

EID: 0030921126     PISSN: 02771691     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004347-199707000-00011     Document Type: Article

References (34)

1. Folkman J, Shing Y. Angiogenesis. J Biol Chem 1992;267: 10931-4.
2. Folkman J. What is the evidence that tumors are angiogenesis-dependent? J Natl Cancer Inst 1990;82:4-6.
3. Liotta L, Kleinerman J, Saldel G. Quantitative relationships of intravascular tumor cells, tumor vessel, and pulmonary metastases following tumor implantation. Cancer Res 1974;34:997-1004.
4. Folkman J, Klagsburn M. Angiogenic factors. Science 1987;235: 442-7.
5. Weidner N, Semple JP, Welch WR, Folkman J. Tumor angiogenesis and metastasis: correlation in invasive breast carcinoma. N Engl J Med 1991;324:1-8.
6. Fidler IJ, Ellis LM. The implications of angiogenesis for the biology and therapy of cancer metastasis. Cell 1994;79:185-8.
7. Kuwano M, Ushiro S, Ryuto M, et al. Regulation of angiogenesis by growth factors. Gann Monogr Cancer Res 1994;42:113-25.
8. Ishikawa F, Miyazono K, Hellman U, et al. Identification of angiogenic activity and the cloning and expression of platelet-derived endothelial growth factor. Nature 1989;338:557-62.
9. Lyons RM, Moses HL. Transforming growth factors and the regulation of cell proliferation. Eur J Biochem 1990;187:467-73.
10. Massague J. The transforming growth factor-β family. Ann Rev Cell Biol 1990;6:597-641.
11. Cannistra SA. Cancer of the ovary. N Engl J Med 1993;329: 1550-9.
12. Kodama J, Hayase R, Okuda H, Yoshinouchi M, Kudo T. Reverse correlation between P-glycoprotein expression and proliferative activity in endometrial adenocarcinoma. Eur J Obstet Gynecol Reprod Biol 1994:45-51.
13. Van Z, Weich HA, Bernart W, Breckwoldt M, Neulen J. Vascular endothelial growth factor (VEGF) messenger ribonucletic acid (mRNA) expression in luteinized human granulosa cells in vitro. J Clin Endocrinol Metab 1993;77:1723-5.
14. Macchiarini P, Fontanini G, Hardin MJ, Squartini F, Angeletti CA. Relation of neovascularization to metastasis of non-small cell lung cancer. Lancet 1992;340:145-6.
15. Gasparini G, Weidner N, Maluta S, et al. Intratumoral microvessel density and p53 protein: correlation with metastasis in head-and-neck squamous cell carcinoma. Int J Cancer 1993;55:739-44.
16. Wakui S, Furusato M, Itoh T, et al. Tumor angiogenesis in prostatic carcinoma with and without bone metastasis: a morphometric study. J Pathol 1992;168:257-62.
17. Horak E, Leek R, Klenk N, et al. Angiogenesis, assessed by platelet/endothelial cell adhesion molecule antibodies, as an indicator of node metastasis and survival in breast cancer. Lancet 1992;340: 1120-4.
18. Bossi P, Viale G, Lee AKC, Alfano RM, Coggi G, Bosari S. Angiogenesis in colorectal tumors: microvessel quantitation in adenomas and carcinomas with clinicopathological correlations. Cancer Res 1995;55:5049-53.
19. Ferrara N, Houck K, Jakeman L, Leung DW. Molecular and biological properties of the vascular endothelial growth factor family of proteins. Endocr Rev 1992;13:18-32.
20. Ferrara N, Leung DW, Cachianes G, Winer J, Henzel WJ. Purification and cloning of vascular endothelial growth factor secreted by pituitary folliculostellate cells. Methods Enzymol 1991;198: 391-405.
21. Houck KA, Ferrara N, Winer J, Cachianes G, Li B, Leung DW. The vascular endothelial growth factor family: identification of a fourth molecular species and characterization of alternative splicing of RNA. Mol Endocrinol 1991;5:1806-14.
22. Yeo T, Senger D, Dvorak H, Freter L, Yeo K. Glycosylation is essential for efficient secretion but not for permeability-enhancing activity of vascular permeability factor (vascular endothelial growth factor). Biochem Biophys Res Commun 1991;3:1568-75.
23. Rak J, Mitsuhashi Y, Bayko L, Filmus J, Shirasawa S, Sasazuki T, Kerbel RS. Mutant ras oncogenes upregulate VEGF/VPF expression: implications for induction and inhibition of tumor angiogenesis. Cancer Res 1995;55:4575-80.
24. Enomoto T, Weghorst CM, Inoue M, Tanizawa O, Rice JM. K-ras activation occurs frequently in mucinous adenocarcinomas and rarely in other common epithelial tumors of the human ovary. Am J Pathol 1991;139:777-85.
25. Senger DR, Galli SJ, Dvorak AM, Perruzzi CA, Harvey VS, Dvorak HF. Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid. Science 1983;219:983-5.
26. Hurteau J, Rodriguez GC, Whitaker RS, et al. Transforming growth factor-beta inhibits proliferation of human ovarian cancer cells obtained from ascites. Cancer 1994;74:93-9.
27. Mukai M, Shinkai K, Komatsu K, Akedo H. Potentiation of invasive capacity of rat ascites hepatoma cells by transforming growth factor-β. Jpn J Cancer Res 1989;80:107-10.
28. Welch DR, Fabra A, Nakajima M. Transforming growth factor β stimulates mammary adenocarcinoma cell invasion and metastatic potential. Proc Natl Acad Sci USA 1990;87:7678-82.
29. Ueki N, Ohkawa T, Yokoyama Y, et al. Potentiation of metastatic capacity by transforming growth factor-β1 gene transfection. Jpn J Cancer Res 1993;84:589-93.
30. Ignotz RA, Massague J. Transforming growth factor-β stimulates the expression of fibronectin and collagen and their incorporation into the extracellular matrix. J Biol Chem 1987;261:4337-45.
31. Ignotz RA, Massague J. Cell adhesion protein receptors as targets for transforming growth factor-β action. Cell 1986;51:189-97.
32. Pepper MS, Vassalli JD, Orci L, Montesano R. Biphasic effect of transforming growth factor-β1 on in vitro angiogenesis. Exp Cell Res 1993;204:356-63.
33. Henriksen R, Gobl A, Wilander E, Oberg K, Miyazono K, Funa K. Expression and prognostic significance of TGF-β isotypes, latent TGF-β1 binding protein, TGF-β type I and type II receptors, and endoglin in normal ovary and ovarian neoplasms. Lab Invest 1995; 73:213-20.
34. Reynolds K, Farzaneh F, Collins WP, et al. Association of ovarian malignancy with expression of platelet-derived endothelial cell growth factor. J Natl Cancer Inst 1994;86:1234-8.